Term
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Definition
T cells
B cells
Natural killer cells |
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Term
Function of primary lymphoid tissue
Give an example of primary tissue |
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Definition
where lymphocytes mature
(bone marrow, thymus) |
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Term
| Function of secondary lymphoid tissue, give an example |
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Definition
Where APCs interact with T or B cells to present antigens
e.g. lymph nodes, spleen, peyers patches, bone marrow |
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Term
| Afferent vs efferent lymphatic vessels |
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Definition
afferent = brings lymph into the lymph node, bringing antigen with it
efferent - activated effector cells (B cells, T cells) leave the nodes and go to their targets |
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Term
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Definition
A motisis-inducing molecule
-can activate B and T cells non-specifically, recruiting abnormally high numbers of lymphocytes without the normal need for a recptor-mediated recognition of the antigen |
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Term
| What are the 2 triggers for Natural Killer cell-mediated killing |
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Definition
-if a cell cuts back on the amount of MHC class I molecules it is expressing, the NK cells will be more likely to kill it
-expression of stress proteins on cells ("kill me pls") |
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Term
| What trimolecular complex is require for NKT cell activation? |
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Definition
| An invariant T cell receptor responds to a special MHC class I molecule caleld CD1d, and then gets activated by glycolipid antigens |
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Term
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Definition
A 'hybrid' between cells of the innate and acquired immune system.
-Have T cell receptor, but can respond to glycolipid antigens, not just peptides, and respond more quickly than normal T cells |
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