Shared Flashcard Set

Details

ID Final
Tuberculosis
35
Anatomy
3rd Grade
12/06/2012

Additional Anatomy Flashcards

 


 

Cards

Term
when did resurgence of tuberculosis hit US?
Definition
1992
Term
most new cases come from what citizens?
Definition
foreign born
Term
TB is _ prevelant infectious disease?
Definition
1st most
Term
how is tuberculosis transmitted?
Definition
droplet nuceli (coughing, sneezing)
Term
how long do you need direct contact to contract TB?
Definition
prolonged
Term
risk factros for aquiring TB-6
Definition
exposure to TB person
geography
HIV
race
adult
Term
which gender has higher chance for getting TB
Definition
male
Term
aveolar macrophages ingest _% of bacteria
Definition
90
Term
host immune response-4
Definition
CD4 actiavte macrophages
macrophages eat bacteria
left over bacteria multiple in macrophage and release on its death
the new bacteria attract more macrophages-> granulomas
Term
host develops antibodies after _ weeks
Definition
3
Term
in healthy patients what are the only sequellae?
Definition
calcifications on x-ray
Term
_% of exposed persons go to active disease
Definition
5
Term
granuloma that is stable, limit spread of infection
Definition
proliferatative
Term
granuloma that is unstable, cheese-like, tissue destruction and spread of TB
Definition
caseating
Term
adaptive immune response causes 2 things
Definition
scarring and lung damage
Term
_% of reactivation
Definition
3-5
Term
risk factros for devloping active disease- 5
Definition
children, elderly (2-5x)
renal failure, cancer (4-16 x)
HIV (100x more risk)
Term
presentaiton of active disease-
normal symptoms- 3
pulmonary-3
Definition
low fever, night sweats, decreased appetite
cough, hemoptysis, chest pain
Term
what test do you use with sputum
Definition
acid-fast bacilli
Term
how is TB skin test admin
Definition
intradermal
5 u/mL
Term
positive test for TB skin test:
no risk factros:
at risk and recent immigration:
HIV, immunosuppression:
Definition
>15 mm
>10 mm
>5 mm
Term
how long do you have to wait to do a TB skin test
Definition
2-8 weeks post exposure
Term
who do you never do a TB skin test on?
Definition
previous positive TST
previous TB treatment
Term
what test is used to determine disease status?
Definition
chest radiograph
Term
Latent Infection diaagnosis - 4 things
Definition
no symptoms
TST, IGRA +
normal chest radiograph
resp cultrue negative
Term
Active Disease diagnosis- 4 things
Definition
symptoms present
TST, IGRA usually +
typically normal radiogrpah
resp smear is pos.
Term
treatment of latent TB should be given to those with a pos. ?
Definition
TST
Term
groups at risk of recent infection (treat for risk of active disease)
Definition
homeless, healthcare worker, long term care
Term
with tuberculosis meds what monitoring is needed
Definition
hepatox
Term
higher rates of INH tox in ages>
Definition
55
Term
non pharmacologic care for active TB- 4
Definition
respiratory isolation
contact investigation
nutrition
notify health department
Term
what 3 mycobacteria does active TB treatment cover?
whihc is the largest group?
Definition
extracellular in cavities
mycobacterium in caseating grans
intracell in macrophages;
extracell
Term
TB consists of _ intitation phase and _ continuation phase - except HIV always treat for _ months
Definition
2 month;
4-7 month;
9
Term
MDR and extrememly drug resisitant tuberculosis require _ # of drugs
how long do you treaT?
Definition
4
18 months after negative culture
Term
monitoring:
do culture and sensitivity follow up in _ months
Definition
2
Supporting users have an ad free experience!