Term
|
Definition
Rhodesian ridgebacks
Epithelial lined tube
Located long dorsal midline
Incomplete separation between ectoderm and neural tube
Connection between skin surface down to meninges
surgical excision to maintain sterility |
|
|
Term
|
Definition
defect in collagen synthesis
increased skin laxity and fragilit
avoid trauma and declaw cats |
|
|
Term
|
Definition
Shar Peis
increased mucin in dermis leads to excessive skin folds with vesicles filled with mucin
increased mucin in oropharynx may impair respiration |
|
|
Term
| Cutaneous Mucinosis Treatment |
|
Definition
corticosteroids can be used to decrease mucin production
pentoxifylline may be beneficial to block collagenase activity |
|
|
Term
| Canine Familial Dermatomyositis |
|
Definition
Shelties and Collies
Show up in young puppies around the time they are weaned |
|
|
Term
| Canine Familial Dermatomyositis Lesions |
|
Definition
scarring, alopecia, blisters around eyes and on bridge of nose
hairless tip to their tail
hocks, perianal region, and extremities affected |
|
|
Term
| Canine Familial Dermatomyositis Signs |
|
Definition
difficulty swallowing and see food being washed into water bowl when drinking
high stepping gait
atrophy of muscles of head and limbs
megaesophagus
aspiration pneumonia
all associated signs with myositis |
|
|
Term
| Canine Familial Dermatomyositis Diagnosis |
|
Definition
biopsy of affected skin and muscle
EMG
vacuolar changes in basal cells
occasional apoptotic basal cell
follicular atrophy and fibrosis
vasculitis/vasculopathy may be present |
|
|
Term
| Canine Familial Dermatomyositis Treatment |
|
Definition
pentoxiphylline
tetracyline
prednisolone
tacrolimus
neuter |
|
|
Term
|
Definition
separation between epidermis and dermis
defects in proteins in basement membrane
dystrophic type=defective Type VII collagen
junctional type= defective laminin 5 |
|
|
Term
| Epidermolysis Bullosa Signs |
|
Definition
| blistering and sloughing of skin subjected to trauma |
|
|
Term
| Epidermolysis Bullosa Diagnosis |
|
Definition
positive Nikolski sign
biopsy |
|
|
Term
| Epidermolysis Bullosa Treatment |
|
Definition
avoid trauma
antibiotics to treat secondary infections |
|
|
Term
| Acral Mutilation Syndrome |
|
Definition
German Short-Haired Pointers, English pointers
sensory neuropathy
chew off toes
no effective treatment |
|
|
Term
|
Definition
Bull Terriers
Can't absorb zinc
Zinc is an important cofactor for everything in the body
Can't make proteins
Toes and toenails grow abnormally
Tend to be aggressive
autosomal recessive |
|
|
Term
| Lethal Acrodermatitis Signs |
|
Definition
growth retardation
progressive acrodermatitis
chronic pyoderma
chronic paronychia
diarrhea
pneumonia
abnormal behavior
survive around 7 months
neutrophilia, hypercholesterolemia, low ALP, low plasma zinc |
|
|
Term
| Lethal Acrodermatitis Management |
|
Definition
treat skin infections
zinc and fatty acid supplements
aloe vera cream
liquid diet
probiotics/yogurt |
|
|
Term
|
Definition
mutations of gene
occurs in German Shepherds
autosomal dominant
multiple nodules develop over limbs and head
dogs usually older than 3 years
associated with renal cystadenocarcinomas and uterine leiomyoma |
|
|
Term
| Nodular Dermatofibrosis Signs |
|
Definition
renal lesions in dogs less than 1 year old
skin biopsies show dense collagen (collagenous nevi) |
|
|
Term
|
Definition
hair loss at birth or within first few months of life
faulty development of hair follicles
other adnexal structure and/or teeth may be abnormal
Chinese crested dog, sphinx cat, Mexican hairless dog |
|
|
Term
| Congenital Hypotrichosis Management |
|
Definition
|
|
Term
| Black Hair Follicle Dysplasia |
|
Definition
Large Munsterlanders dogs, Terriers, Chihuahuas, mixed breeds
black areas have broken hairs and hair loss
white areas have normal hair |
|
|
Term
| Black Hair Follicle Dysplasia Diagnosis |
|
Definition
| trichogram shows clumped melanin and distorted hairs |
|
|
Term
| Black Hair Follicle Dysplasia Management |
|
Definition
emollients
ethyl lactate shampoo
melatonin |
|
|
Term
|
Definition
produced by pineal gland during periods of darkness
stimulates anagen (growth phase)
may also down-regulate androgen receptor activity |
|
|
Term
|
Definition
aka Blue domerman syndrome
any blue colored dogs can be affected
melanin clumping in hair bulbs and shafts results in brittleness
hairs break
secondary infections common |
|
|
Term
| Color Mutant Alopecia Management |
|
Definition
follicle flushing shampoos
antibiotics for secondary infections
melatonin |
|
|
Term
| Canine Recurrent Flank Alopecia |
|
Definition
Airdale terries, boxers, english bulldogs
genetic cyclic follicular dysplasia associated with deficiency of melatonin
onset may be fall or spring
not pruritic |
|
|
Term
| Canine Recurrent Flank Alopecia Diagnosis |
|
Definition
rule out other causes of multifocal alopecia
biopsy shows market follicular hyperkeratosis
follicular plugging results in distortion of hair follciles |
|
|
Term
| Canine Recurrent Flank Alopecia Management |
|
Definition
|
|
Term
| Follicular Dysplasia of Curly-Coated Breeds |
|
Definition
Irish Water Spaniels
Chesapeake Bay Retrievers
Portugese Water Dogs
Siberian huskies
primary hairs break
secondary hairs are lighter and more wooly
hair loss on trunk, thighs, neck |
|
|
Term
| Follicular Dysplasia of Curly-Coated Breeds Diagnosis |
|
Definition
rule out other causes
biopsies |
|
|
Term
| Follicular Dysplasia of Curly-Coated Breeds Management |
|
Definition
ethyl lactate shampoo
antiseborrheic shampoos and sprays
melatonin
treat secondary infections |
|
|
Term
|
Definition
| Daschund, Boston terrier, Chihuahua, Whippet, Italian greyhoud, Greyhoud, Boxer, Mini pin, Manchester terrier |
|
|
Term
| Canine Pattern Baldness Signs |
|
Definition
4 common patterns
pinnal alopecia
neck, thigh and tail alopecia
caudal thighs and ventral abdomen alopecia
post-auricular, ventral neck, ventral abdomen, thigh alopecia |
|
|
Term
| Canine Pattern Baldness Diagnosis |
|
Definition
rule out other signs
biopsy |
|
|
Term
| Canine Pattern Baldness Management |
|
Definition
|
|
Term
|
Definition
| Daschund, Boston terrier, Chihuahua, Whippet, Italian greyhoud, Greyhoud, Boxer, Mini pin, Manchester terrier |
|
|
Term
| Canine Pattern Baldness Signs |
|
Definition
4 common patterns
pinnal alopecia
neck, thigh and tail alopecia
caudal thighs and ventral abdomen alopecia
post-auricular, ventral neck, ventral abdomen, thigh alopecia |
|
|
Term
| Canine Pattern Baldness Diagnosis |
|
Definition
rule out other signs
biopsy |
|
|
Term
| Canine Pattern Baldness Management |
|
Definition
observation
melatonin
methytestosterone
ketoconazole
triostane
op'DDD |
|
|
Term
| Schnauzer Comedo Syndrome |
|
Definition
miniature Schnauzer affected
along dorsal midline see comedones and crusted papules
due to hair follicle keratinization defect |
|
|
Term
| Schnauzer Comedo Syndrome Diagnosis |
|
Definition
|
|
Term
| Schnauzer Comedo Syndrome Management |
|
Definition
follicle flushing shampoos
antiseptic wipes
antibiotics |
|
|
Term
|
Definition
normal is 21 days
time for cell to move from basal cell layer to stratum corneum for exfoliation
inflammation speeds up keratinization |
|
|
Term
|
Definition
| develops if changes in mitotic rate, process of keratinization, or abnormalities in desquamation |
|
|
Term
|
Definition
| accumulation of scales and/or sebum on skin surface that is dry |
|
|
Term
|
Definition
| accumulation of scales and/or sebum on skin surface that is dry that is oily |
|
|
Term
|
Definition
| accumulation of scales and/or sebum on skin surface that is dry that is inflamed |
|
|
Term
|
Definition
| hereditary abnormality in keratin formation, sebum formation, or intercellular lipids |
|
|
Term
|
Definition
| underlying disease, drug, or environmental condition responsible for development |
|
|
Term
| Primary Seborrhea in Cocker Spaniels |
|
Definition
epidermal cell renewal time of 8 days compared to normal time of 21 days
basal mitotic index may be 3-4X normal |
|
|
Term
|
Definition
antiseborrheic shampoos
control of secondary infections
moisturizers
vitamin A
acriretin
isotretinoin
topical retinoids |
|
|
Term
|
Definition
breaks down junctions between cells in stratum cornea
Makes them look better right away
breaks down keratin |
|
|
Term
|
Definition
Decreases DNA synthesis in stratum basale
Slows down mitotic rate
Has to penetrate through epidermis to get down that deep
10 minute contact time
The longer the contact time the better
Need to do this every day or every other day for a while
Won't dry out their hair coats with these medicated shampoos |
|
|
Term
|
Definition
solubilizes lipids
suppresses sebaceous glands |
|
|
Term
|
Definition
| restores intercellular lipids |
|
|
Term
|
Definition
primary keratinzation problem
abundant scales
keratinous projections |
|
|
Term
| Epidermolytic Canine Ichthyosis |
|
Definition
| Norfolk terrier, rhodesian ridgeback, lab, cavalier king charles spaniel |
|
|
Term
| Nonepidermolytic Canine Ichthyosis |
|
Definition
Jack Russell terrier, Australian terrier, Cairn terrier, Norfolk terrier, American bulldog, Golden retriever
defect in intercellular lipids, cornified envelop, or desmosomes
skin does not exfoliate correctly
need EM to diagnose |
|
|
Term
| Canine Ichthyosis Management |
|
Definition
hydrotherapy
topical antiseborrheics
emollients
reitnoids
vitamin A |
|
|
Term
|
Definition
Standard poodle, Akit, Vizsla, Samoyed
young to middle aged |
|
|
Term
|
Definition
symmetrical alopecia, scaling
dry coat on dorsum, nose, tail, pinna, trunk
follicular casts and matting
moth-eaten alopecia
secondary pyoderma
hairs epilate easily and lots of derbis around hair shafts |
|
|
Term
| Sebaceous Adenitis Treatment |
|
Definition
follicle flushing shampoos
moisturizers
isotretinoin
vitamin A
tetracycline
cyclosporine
treat secondary infections
no cure |
|
|
Term
| Exfoliative Cutaneous Lupus Erythematosus |
|
Definition
German Shorthaired pointers
autosomal recessive
lesion starts 6 mo - 3 years |
|
|
Term
| Exfoliative Cutaneous Lupus Erythematosus Signs |
|
Definition
scaling on face, ears, dorsum
painful and pruritic
may wax and wane
peripheral lymphadenopathy
secondary pyoderma |
|
|
Term
| Exfoliative Cutaneous Lupus Erythematosus Treatment |
|
Definition
antiseborrheaic therapy
treat secondary pyoderma
cyclosporin helps but doesn't cure
prognosis is guarded
omega 3 FA
carprofen for pain |
|
|
Term
|
Definition
Their skin becomes very thickened and wrinkled due to intense lichenification
look like armadillo |
|
|
Term
|
Definition
Daschunds
or due to secondary problems
darkening of skin
Vitamin E and lose weight |
|
|
