| Term 
 
        | Primary purpose of the prostate gland: |  | Definition 
 
        | decrease viscosity of semen to facilitate transport |  | 
        |  | 
        
        | Term 
 
        | Why are prostatic secretions alkalilne? |  | Definition 
 
        | to neutralized the acidity of the male urethra and female vagina during intercourse to preseve intergrity and lifespan of sperm |  | 
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        | Term 
 
        | what age should DRE be discontinued? |  | Definition 
 
        | 75 unless there is an aggressive tumor, in which case they may have substantial benefits |  | 
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        | Term 
 
        | recommended prostate biopsy technique: |  | Definition 
 
        | TRUS- transrectal ultrasound guided prostate biopsy, extended pattern 12 core biopsy- 6 towrads the lateral peripheral zone and 6 torwards abnormal palpable nodule |  | 
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        | Term 
 
        | High grade prostatic intraepithelial neoplasia (HGPIN): |  | Definition 
 
        | - confirms atypical cells that have NOT yet transversed basement membrane |  | 
        |  | 
        
        | Term 
 
        | Atypia, suspicious for cancer: |  | Definition 
 
        | - contains cells that appear atypical but a dx of malignancy cannot be made or ruled out - requires follow-up extended biopsy with additional cores from the atypical region within a 3 month time frame
 |  | 
        |  | 
        
        | Term 
 
        | when is repeat biopsy recommended: |  | Definition 
 
        | - for patients whose PSA levels continue to rise following negative biopsy results 
 2 negative or unequivocal biopsies and pts PSA continues to rise> saturation biopsy
 |  | 
        |  | 
        
        | Term 
 
        | active surveillance/watchful waiting/expectant management/conservative care for prostate cancer: |  | Definition 
 
        | - PSA and DRE every 3-6 months - yearly prostate biopsy
 |  | 
        |  | 
        
        | Term 
 
        | follow up after successful treatment of prostate cancer: |  | Definition 
 
        | - PSA and DRE every 6 months for 5 years - after th3 5 years, annual follow up
 |  | 
        |  | 
        
        | Term 
 
        | overall 5 year survival rate for prostate cancer: |  | Definition 
 | 
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