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GU: Common Male Disorders
GU: Common Male Disorders
8
Anatomy
Graduate
01/22/2012

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Cards

Term
Klinefelter's has the genotype __ and they have __ of the seminiferous tubules.
Definition
XXY
fibrosis

also have increased risk for breast cancer compared to most males
Term
Lab findings with Klinefelters:
Definition
- High FSH: LH ratio
- Low sperm count
- Low inhibiin
- Small testicular volume
- Normal to low testosterone
- High estrogen
Term
Pts with Klinefelter's Syndrome have __ testosterone: estrogen ratio.
Definition
decreased
Term
Klinefelters is a ___ testicular problem.
Definition
primary
Term
exogenous anabolic steroids> negative feedback to pituitary that there is too much testosterone> decreased LH> Leydig cell not stimulated to make testosterone> Sperm count drops b/c no local testosterone> decreased inhibin> increased FSH
Definition
Term
With both Klinefelter's and Anabolic steroid use, ___ is ___. But with Klinefelter's LH is __ to __, whereas with steroids, LH is ___.
Definition
- FSH is high
- Klinefelters LH is normal to low
- Steroids LH is low
Term
3 options for tmt of BPH:
Definition
- Reductase inhibitors
- Androgen receptor blockers
- GnRH analoge to inhibit LH
Term
Prostate CA tmt options:
Definition
- Reductase inhibitors
- Androgen receptor inhibitors
- LH inhibition with estrogen or GnRH analogue
- Orchiectomy
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