Term
| Klinefelter's has the genotype __ and they have __ of the seminiferous tubules. |
|
Definition
XXY
fibrosis
also have increased risk for breast cancer compared to most males |
|
|
Term
| Lab findings with Klinefelters: |
|
Definition
- High FSH: LH ratio
- Low sperm count
- Low inhibiin
- Small testicular volume
- Normal to low testosterone
- High estrogen |
|
|
Term
| Pts with Klinefelter's Syndrome have __ testosterone: estrogen ratio. |
|
Definition
|
|
Term
| Klinefelters is a ___ testicular problem. |
|
Definition
|
|
Term
| exogenous anabolic steroids> negative feedback to pituitary that there is too much testosterone> decreased LH> Leydig cell not stimulated to make testosterone> Sperm count drops b/c no local testosterone> decreased inhibin> increased FSH |
|
Definition
|
|
Term
| With both Klinefelter's and Anabolic steroid use, ___ is ___. But with Klinefelter's LH is __ to __, whereas with steroids, LH is ___. |
|
Definition
- FSH is high
- Klinefelters LH is normal to low
- Steroids LH is low |
|
|
Term
| 3 options for tmt of BPH: |
|
Definition
- Reductase inhibitors
- Androgen receptor blockers
- GnRH analoge to inhibit LH |
|
|
Term
|
Definition
- Reductase inhibitors
- Androgen receptor inhibitors
- LH inhibition with estrogen or GnRH analogue
- Orchiectomy |
|
|
