| Term 
 | Definition 
 
        | - abnormally frequent discharge of semisolid or fluid fecal matter from the bowel 
 - > 200 g/day
 - > 15 g/kg under 2 y/o
 |  | 
        |  | 
        
        | Term 
 
        | Medications that may cause diarrhea: |  | Definition 
 
        | - Metformin - Exenatide
 - Theophylline
 - Colchicine
 - PPI's
 - HAART
 - Antibiotics- erythromycin
 - Promotility agents
 - Laxatives
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - loose watery stools - NO blood, mucus, or WBCs
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Metronidazole 250 mg tid x 5 days |  | 
        |  | 
        
        | Term 
 
        | Parasitic cause of diarrhea that is self limiting in most pple, but lifethreatening in AIDs. Tend to have > 17 liters/diarrhea. This parasite has an outer coat so its resistant to chlorine. Leading cause of recreatiional water associated gastroenteritis: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | This type of E.coli adheres to the small bowel and releases 2 enterotoxins: |  | Definition 
 
        | Enterotoxigenic E. coli > Traveler's diarrhea |  | 
        |  | 
        
        | Term 
 
        | Difference b/w diarrhea with Enterohemorrhagic E. coli and Enterotoxigenic E. coli: |  | Definition 
 
        | - Enterohemorrhagic: bloody diarrhea - Enterotoxigenic: no blood, mucus, or WBC
 |  | 
        |  | 
        
        | Term 
 
        | Enteroinvasive bacteria that mimic Shigella by causing local colonic inflammatory response: |  | Definition 
 
        | - Enterotoxigenic E. coli |  | 
        |  | 
        
        | Term 
 
        | Onset of symptoms and duration of symptoms with Salmonella: |  | Definition 
 
        | - onset: 8-48 hours after exposure - duration: 1-2 weeks
 |  | 
        |  | 
        
        | Term 
 
        | What type of diarrhea occurs with salmonella? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Salmonella Typhi symptoms: |  | Definition 
 
        | - Headache - Cough
 - Sore throat
 - Malaise
 - Anorexia
 - Diaphoresis
 - Abdominal pain
 - Constipation
 - Pea soup diarrhea
 |  | 
        |  | 
        
        | Term 
 
        | Shigella diarrhea and other shigella symptoms? |  | Definition 
 
        | - watery diarrhea - tenesmus
 - fever
 - stomach cramps
 |  | 
        |  | 
        
        | Term 
 
        | Shigella causes watery diarrhea, but there may also be __ or __ in the stools. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | complications of shigella: |  | Definition 
 
        | - febrile seizures - encephalopathy
 - Reiter syndrome
 |  | 
        |  | 
        
        | Term 
 
        | With shigella __ should be avoided, but ___ should be used. |  | Definition 
 
        | - antidiarrheals should be avoided - antibiotics should be used
 |  | 
        |  | 
        
        | Term 
 
        | Antibiotis to treat Shigella: |  | Definition 
 
        | - Ceftriazone 250 mg IM - Ciprofloxacin 250 mg bid x 5 days
 - SMZ/TMP bid x 5 days
 - Azithromycin 500 mg for first day, 250 mg for 4 more days
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - loose, watery, or bloody stools |  | 
        |  | 
        
        | Term 
 
        | Campylobacter is self-limiting but has a shorter course with antibiotics, what antibiotics would you use? |  | Definition 
 
        | - Erythromycin 250-500 mg/day for 5-7 days - Ciprofloxacin 500 mg BID x 3 days
 |  | 
        |  | 
        
        | Term 
 
        | Complications of Campylobacter jejuni? |  | Definition 
 
        | - Hemolytic Uremic Syndrome (HUS) - Guillain Barre (40%)
 |  | 
        |  | 
        
        | Term 
 
        | 2 bacterial causes of diarrhea that may cause HUS: |  | Definition 
 
        | - Enterohemorrhagic E. coli - Campylobacter jejuni
 |  | 
        |  | 
        
        | Term 
 
        | Bacterial diarrhea from undercooked pork products: |  | Definition 
 
        | - Yersinia enterocolitica |  | 
        |  | 
        
        | Term 
 
        | bacterial diarrhea that makes you unable to chelate iron? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | bacterial diarrhea that causes pseudoappendicitis? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Complications of Yersinia enterocolitica: |  | Definition 
 
        | - Erythema nodosum - Reiter syndrome
 |  | 
        |  | 
        
        | Term 
 
        | Two causes of bacterial diarrhea that can result in Reiter Syndrome: |  | Definition 
 
        | - Shigella - Yersinia enterocolitica
 |  | 
        |  | 
        
        | Term 
 
        | Tmt for Yersinia enterocolitica: |  | Definition 
 
        | - Levofloxacin - Ciprofloxacin
 - SMZ/TMP
 - Ceftriaxone
 |  | 
        |  | 
        
        | Term 
 
        | Causes of Clostridium difficile: |  | Definition 
 
        | - Cephalosporins - Clindamycin
 - Ampicllin
 - Amoxicillin
 - Chemo
 |  | 
        |  | 
        
        | Term 
 
        | Complications of C. diff: |  | Definition 
 
        | - Pseudomembranous colitis: 2-10 mm plaques, up to 25% of pts with mild disease - Toxic megacolon
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - Vancomycin 125 mg QD for 10-14 days - Metronidazole 250 mg QD for 10-14 days
 - Bacteriotherapy- stool transfer from someone else
 |  | 
        |  | 
        
        | Term 
 
        | Vibrio parahaemolyticus is found in __ __ and is associated with __ __. |  | Definition 
 
        | - brackish saltwater - undercooked shellfish
 |  | 
        |  | 
        
        | Term 
 
        | Vibrio parahaemolyticus symptoms: |  | Definition 
 
        | - watery diarrhea - abomdinal cramping
 - nausea
 - vomiting
 - fever
 - chills
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - watery rice water stools - vomiting
 - leg cramps
 |  | 
        |  | 
        
        | Term 
 
        | Where does Vibrio cholera occur: |  | Definition 
 
        | - Indian subcontinents - sub-Sarahan Africa
 - coastal TX and LA
 |  | 
        |  | 
        
        | Term 
 
        | focus of tmt with Vibrio cholera: |  | Definition 
 
        | - rehydration more important than antibiotics |  | 
        |  | 
        
        | Term 
 
        | What type of bacterial diarrhea will antibiotics not work against and why? |  | Definition 
 
        | Staphylococcus aureus b/c the abx won't kill the toxin and thats what makes you sick |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - undercooked meats, poultry, or legumes - diarrhea and cramps
 - treat with rehydration
 |  | 
        |  | 
        
        | Term 
 
        | Screen and dx for Celiac Disease: |  | Definition 
 
        | Screen with autoantibodies: - Anti-tissue transglutaminase (tTGA)
 - IgA Anti-gliadin antibodies
 - IgA Anti-endomysial antibodies
 
 Diagnsosis
 - Fecal fat Sudan stain
 - GOLD STANDARD: SMALL BOWEL BIOPSY
 |  | 
        |  | 
        
        | Term 
 
        | Foods pts with Celiac can eat: |  | Definition 
 
        | CRAP and more 
 - Corn
 - Rice
 - Arrowroot
 - Potatoes
 - Soy
 - Buckwheat
 - Quinoa
 - Flax
 - Tapioca
 |  | 
        |  | 
        
        | Term 
 
        | Symptoms of Whipple's Syndrome: |  | Definition 
 
        | - Arthralgias - Weight loss
 - Diarrhea
 - Abdominal pain
 - Cough
 - Lymphadenopathy
 - Fever
 
 results in MALABSORPTION fatal if untreated
 |  | 
        |  | 
        
        | Term 
 
        | Examples of conditoin that can lead to bacterial overgrowth and thus malabsorption: |  | Definition 
 
        | - Gastric achlorhydria- due to gastric surgery or chronic PPI use - Radiation enteritis
 - Motility disordres
 - Fistulas
 - Elderly
 |  | 
        |  | 
        
        | Term 
 
        | one of the most common complications of having gall bladder removed: |  | Definition 
 
        | diarrhea after surgery, can be acute or chronic 
 treat with cholestyramine
 |  | 
        |  | 
        
        | Term 
 
        | Chronic diseases tha may cause diarrhea: |  | Definition 
 
        | - IBD - Microscopic colitis
 - Radiation colitis
 |  | 
        |  | 
        
        | Term 
 
        | Microscopic colitis treatment: |  | Definition 
 
        | - Loperamide or Diphoxylate/atropine - Bismuth subsalicylate
 - 5 ASA/Sulfasalzine
 - Budesonide or Prednisone
 |  | 
        |  | 
        
        | Term 
 
        | Examples of diseases that cause motility disorders of the gut: |  | Definition 
 
        | - IBS - DM
 - Scleroderma
 - Hyperthyroidism
 - Addison's
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Antispasmodics: - Hyoscamine
 - Dicyclomine
 |  | 
        |  | 
        
        | Term 
 
        | Sign of colonoscopy of laxative abuse: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Diverticulosis coli usually affects the __ colon. |  | Definition 
 | 
        |  |