Term
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Definition
gall bladder stones
incidental in animals that are chronically ill and not eating
seldomly cause obstruction in animals |
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Term
|
Definition
Canine Distemper Virus
Infectious Canine Hepatitis
necrosis of gall bladder epithelium with secondary hemorrhage |
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Term
|
Definition
Salmonella enteriditis in calves
migrates up biliary tract from gut
fibrinous exudate and edema of gall bladder wall |
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Term
|
Definition
small breed dogs
gallbladder fills with mucous until it ruptures
hyperplasia of gall bladder epithelium produces abundant mucous |
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Term
| Cystic Mucosal Hyperplasia |
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Definition
dogs, sheep
incidental finding
mucous production that does not rupture the gall bladder |
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Term
| Incidental Lesions of the Pancreas |
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Definition
infiltration of mesenteric fat in interlobular interstitium makes it look atrophied
pancreatic calculi in ruminants |
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Term
| Juvenile Pancreatic Atrophy |
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Definition
German Shepherds, Collies 6-12 months old
immune mediated apoptosis of pancreatic acinar cells |
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Term
|
Definition
overweight sedentary female dogs
necrosis is major problem
regeneration can occur if there is no neutrophil infiltration
once fibrosis starts, connective tissue traps and squeezes down on remaining acinar cells |
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Term
| Causes of Acute Pancreatitis |
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Definition
Three mechanisms:
Biliary Reflux due to obstruction on biliary outflow which activates pancreatic enzymes prematurely
Direct damage to acinar cells from trauma, toxin
Overstimulation of acinar cells causing zymogen to spread in pancreas and digest it with neutrophil infiltration |
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Term
| Gross Features of Acute Pancreatitis |
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Definition
prominent interstitial edema in mild cases
hemorrhagic, pale foci of necrosis and saponified fat in severe cases |
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Term
| Histopathology of Acute Pancreatitis |
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Definition
necrosis and inflammation beginning at edges of lobules or from ducts and moving out
fibrinous adhesions of abdominal organs |
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Term
| Sequelae to Acute Pancreatitis |
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Definition
Abscesses
Adhesions
Intra-abdominal hemorrhage
Icterus due to extrahepatic cholestasis
Vascular damage, shock, DIC, pulmonary edema, myocardial depression |
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Term
|
Definition
from repeated acute pancreatitis or biliary reflux
interstitial and periductal lymphocytic infiltration and fibrosis
lumpy shrunken pancreas |
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Term
| Causes of Chronic Pancreatitis |
|
Definition
Cats- ascending bacterial infection
Sheep- zinc toxicosis
Horses- fluke migration and bacterial infection |
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Term
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Definition
incidental finding in old dogs/cats
multifocal raised, smooth, uniform gray nodules
acinar cells are slightly enlarged but normal |
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Term
|
Definition
rare
large hyperplastic nodule with thin capsule |
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Term
|
Definition
uncommon
solitary or multicentric
invasive and rapidly spreading
abundant fibrotic response so tumor adheres to anything in its vicinty |
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