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| another way cells bind to one another; neighboring cell’s plasma membranes are linked by integral proteins; three major types exist |
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| three major types of cell junctions: |
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| hold cells closely together; space between is impermeable to movement of macromolecules |
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| In tight junctions, integral proteins of adjacent cell's plasma membranes are ______ _________; form seal around apical perimeter of cell. This seal may not be complete, allowing for ________ in some tissues. |
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| tight junctions example: tight junctions exist inside the _______ ________ to keep _______ from.... |
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digestive tract; bacteria; entering other tissues
[note how it keeps something from entering a nearby tissue] |
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| linking integral proteins; allow for materials in extracellular fluid to pass through space between cells |
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| desmosomes increase strength of tissue by..........; mechanical stress is more ____ ______ |
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| holding cells together; evenly distributed |
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| ______________________ are attached to ___________ of cytoskeleton for structural reinforcement in desmosomes |
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| integral "linker" proteins; intermediate filaments |
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| desmosomes can be found in... |
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| tissues subjected to a great deal of mechanical stress (epithelia of skin) |
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| desmosome example: exist in _____ to .... |
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| bladder; hold cells together as bladder fills |
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small pores formed by protein channels between adjacent cells; allow small substances to flow freely between each cell’s cytoplasm such as ions |
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| gap junctions are located in... |
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–In between cells that communicate with electrical signals such as cardiac muscle cells. |
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| Cell–Cell Communication Core Principle |
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on every internal and external body surface; barrier between body and external environment; line organs and fluid-filled cavities |
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