Term
| Flaviridae Characteristics |
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Definition
enveloped, ssRNA, positive sense
labile, short incubation
E protein-surface glycoprotein with hemagglutination activity, neutralizing target
Pesitvirus, Falvivirus, Hepacivirus |
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Term
| Flaviridae Entry, Replication, Release |
|
Definition
receptor mediated endocytosis
replication in cytoplasm
gets envelope in RER
exocytosis by cytoplasmic vesicles and then cytolysis |
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Term
|
Definition
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Term
|
Definition
pestivirus-lymphoid tissue and epithelium
flavivirus-neurons |
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Term
| Bovine Viral Diarrhea Virus Characteristics |
|
Definition
type 1 - classic BVDV
type 2- atypical (virulent for all ages) |
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Term
| Bovine Viral Diarrhea Virus Signs |
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Definition
type 2-hemorrhagic syndrome, anorexia, respiratory disease, diarrhea, death in 2 days
virus induced immunosuppression |
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Term
| Bovine Viral Diarrhea Virus Biotypes |
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Definition
for type 1
noncytopathic- most common, establishes persistent infection
cytopathic- acute infections, mutant of ncp or exogenous |
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Term
| Bovine Viral Diarrhea Virus Tropism |
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Definition
lymphoid tissue
mucosal epithelium |
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Term
| Bovine Viral Diarrhea Virus Transmission |
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Definition
orofecal route
repiratory
urine and semen
transplacental
swine, sheep, goats, deer are reservoirs |
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Term
| Bovine Viral Diarrhea Virus Enteric Disease |
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Definition
acute BVDV infection of immunocompetent animals
mild enteric disease
virus-induced immunosuppression |
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Term
| Bovine Viral Diarrhea Virus In utero |
|
Definition
death of calf or peristent infection
cypathic biotype before 150days gestation = abortion
noncytopathic biotype before 150 days gestation = immune tolerance and PI calf or congenital malformations
noncytopathic biotype after 150 days gestation = normal calf |
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Term
| Bovine Viral Diarrhea Virus Diagnosis |
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Definition
PI animal is sero-negative
life-long shedding of virus |
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Term
| Bovine Viral Diarrhea Virus Control |
|
Definition
cull PI animals
keep only seropositive animals
MLV vaccine
booster with killed product
animals will shed MLV vaccine virus |
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Term
| Classic Swine Fever Virus Characteristics |
|
Definition
aka hog cholera
REPORTABLE
eradicated in US |
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Term
| Classic Swine Fever Virus Tropism |
|
Definition
| reticuloendothelial and endothelium |
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Term
| Classic Swine Fever Virus Signs |
|
Definition
acute febrile hemorrhagic disease
subacute or chronic wasting with hemorrhages and reproductive problems |
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Term
| Classic Swine Fever Virus Transmission |
|
Definition
in utero
fetus is immunologically tolerant resulting in PI or death
virus sheds in all secretions/excretions
garbage feeding |
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Term
| Classic Swine Fever Virus Control |
|
Definition
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Term
| West Nile Virus Characteristics |
|
Definition
enzootic in USA since 2003
zoonotic
equids are dead end hosts |
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Term
|
Definition
neurons
endothelium, dendritic, or lymphoid tissue |
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Term
| West Nile Virus Transmission |
|
Definition
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Term
|
Definition
vector control
equine vaccine |
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