Term
| impact of fractures affects? |
|
Definition
|
|
Term
| is osteoporosis preventable? |
|
Definition
|
|
Term
| 2 broad non-pharm ways to prevent osteoporosis |
|
Definition
increase bone mass
social and diet changes |
|
|
Term
when does bone mass peak?
when would be best to try to increase this mass? |
|
Definition
|
|
Term
what age is social/diet change msot important?
what are 3 points to this change? |
|
Definition
any age
smoking cessation, only 2 drinks/day, decrease caffeine |
|
|
Term
| what are 2 fall prevention techniques |
|
Definition
strength exercises
safe home env |
|
|
Term
| what is a surrogate marker? |
|
Definition
|
|
Term
| evidence of benefits of men comes from? |
|
Definition
|
|
Term
| adequate_ and _ intake is absolute |
|
Definition
|
|
Term
what dose of Ca is needed to see benefit
what is neede in combo to decrease fractures? |
|
Definition
|
|
Term
| what does NOF reccomend for Ca intake? |
|
Definition
|
|
Term
what elemental Ca has the most %?
which has the least? |
|
Definition
Calcium carbonate
calcium gluconate |
|
|
Term
insoluble/soluble Ca is favored in most?
do you take it with meals?
what pH is needed? |
|
Definition
|
|
Term
| soluble/insoluble Ca is preferred in acholhydria? |
|
Definition
| soluble (doesnt need acidic pH) |
|
|
Term
Calcium carbonate:
dose?
cost?
meal? |
|
Definition
1 tab per dose
cheap
needs meals |
|
|
Term
clacium citrate
dose?
cost?
meals? |
|
Definition
2 tabs per dose
expensive
doesnt need meals |
|
|
Term
| which Ca is better for acholhydria or older patients? |
|
Definition
|
|
Term
_ needs to be replete prior to osteoporosis therapy?
what shows this? |
|
Definition
Vit D
25-Oh greater than 30 |
|
|
Term
| risk factors for Vit D deficiency-6 |
|
Definition
limited sun
malabsorption
meds
dark skin
obese
CKD |
|
|
Term
| NOF reccomneds Vit D intake of- |
|
Definition
|
|
Term
repletion doses for Vit D2
for D3
how long do you treat for? |
|
Definition
ergocalciferol
cholecaliferol
8-12 weeks |
|
|
Term
| > _ mg of vit D or Ca wont be absorbed per meal |
|
Definition
|
|
Term
| what is the most common ADE of Ca or Vit D |
|
Definition
|
|
Term
| BPs approved by FDA to prevent and AND treat osteoporosis? |
|
Definition
|
|
Term
BPS shown to decrease what fractures?
which specific one decreases mortality |
|
Definition
hip, verrtebral
zoledronic |
|
|
Term
| which Ca meds are insoluble |
|
Definition
|
|
Term
do you not take BPs?
what do you take? |
|
Definition
Food! low orlal bioavailability
full glass of water |
|
|
Term
| what intake must be adequiate to use BPs |
|
Definition
|
|
Term
| what patients should BP be avoided-2 |
|
Definition
|
|
Term
|
Definition
osteonecrosis of jaw
atrial fib
muscoskel pain
femur fractures |
|
|
Term
| what is the 1st line therapy for OP |
|
Definition
|
|
Term
| which med is approved for ppl at high risk of future fracture? |
|
Definition
|
|
Term
how is teriparatide dosed and admin?
max yrs of use? |
|
Definition
|
|
Term
| teriparatide is best if used? |
|
Definition
|
|
Term
| Denosumab is approved for? -4 |
|
Definition
post menopausal OP
OP in men
adrogen bone loss in men w/ prost cancer
aromatse bone loss in women w/ breat cancer |
|
|
Term
| what med supresses bone turnover? |
|
Definition
|
|
Term
| what med is FDA approved for prevention of post menopausal OP? |
|
Definition
|
|
Term
what is the dose for estrogen?
need to utilize _ if have intact uterus |
|
Definition
.625 or lower of CEE
progestin |
|
|
Term
| estrogen/ non estorgen for 1st line prevention? |
|
Definition
|
|
Term
| if use estrogen need to emphasize need for _ |
|
Definition
|
|
Term
| which med is a estrogen receptor modulator |
|
Definition
|
|
Term
what is raloxifene approved for?
what is the dose |
|
Definition
prevention and treatment
60 mg 1x daily |
|
|
Term
| what is ADE of raloxifene |
|
Definition
hot flashes
thromboembo events (clot) |
|
|
Term
| if immobility is planned need to stop raloxifene _ days before |
|
Definition
|
|
Term
calcitonin is admin 2 ways-
which is cheaper and better tolerated? |
|
Definition
|
|
Term
| _ adequate intake is needed to take calcitonin |
|
Definition
|
|
Term
| calcitonin is primarily used in ppl with _ associated wiht OP |
|
Definition
|
|
Term
| men comprise _/5 hip fracture |
|
Definition
|
|
Term
| do men or women have hgiher mortality with hip fracture? |
|
Definition
|
|
Term
| what hormone plays role in men's OP |
|
Definition
|
|
Term
| whcih med needs perosn to be upright 30 min |
|
Definition
|
|
Term
|
Definition
|
|
Term
| what two meds arent for treatment in OP for men? |
|
Definition
|
|
Term
how often should DXA be done
-what can pay for this? |
|
Definition
|
|
