Term
| What are the two divisons of the pituitary gland? |
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Definition
Neurohypophysis (posterior pituitary)
Adenohypophysis (anterior pituitary) |
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Term
| The Neurohypophysis is composed of axons whose cell bodies reside in the ________ and ______________ of the hypothalamus |
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Definition
| supraoptic and paraventricular nuclei |
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Term
| What are the 3 divsions of the adenohypophysis? |
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Definition
1. pars tuberalis
2. pars intermedia
3. pars distalis |
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Term
| How are neurohypophysis hormones secreted? |
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Definition
| by the cell bodies of neurons in the supraoptic and paraventricular nuclei of the hypothalamus to the NH portion of the pituitary. |
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Term
| how are adenohypophyseal hormones synthesized? |
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Definition
| hypothalamic hormones at the AH down HP stalk by way of "portal veins" and pituitary hormones leave in blood vessels |
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Term
| What influences the hypothalamus? |
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Definition
Sensory input to the brain
thirst, appetite, body temp |
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Term
| Neurotransmitters that influence the hypothalamus....what are they? |
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Definition
NADS!
NE, Ach, Dopamine, Seritonin |
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Term
| Secretion of the hypothalamus is ________________. |
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Definition
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Term
| What are the hypothalamic hormones? |
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Definition
Terry gets charged (for) releasing greg in gorgia (and)promoting promiscutity:
TRH
GnRH
CRH
GHRH
GHIH
PIF
PRF |
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Term
|
Definition
| specific protien transcription factor |
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Term
| what are the 5 trophic cells? |
|
Definition
corticotrophs
thyrotrophs
somatotrophs
gonadotrophs
mammotrophs |
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Term
| Pituitary secretion is ____________. |
|
Definition
|
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Term
| What regulates AH control? |
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Definition
hypothalamus
leptin
interlukins
endogenous cannabionoids |
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Term
| what are the hormones secreted by the adenohypohysis? |
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Definition
all the girls like free products and options
ACH
TSH
GH
LH
FSH
[ADH oxytocin]--> neurohypohysis |
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Term
| what is the prepro of ACTH synthesis? |
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Definition
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Term
| ACTH secretion is _________________. |
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Definition
|
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Term
| what are the gonadotropic hormones? |
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Definition
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Term
| What hormones inhibit LH and FSH? |
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Definition
| inhibin, test/estro, follistatin, melatonin |
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|
Term
| what does prolactin play a role on? |
|
Definition
Lactation-- stimulates the mams
Reproduction -- inhibits GnRH |
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Term
| what is another name for GH? |
|
Definition
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Term
| secretion of GH is ______________. |
|
Definition
| pulsatile with a potential nocturnal peak |
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Term
| what is an anabolic effect? |
|
Definition
| anything that builds up tissues or organs |
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|
Term
| what is a catabolic effect? |
|
Definition
| metabolisim that breaks down molecules and tissues |
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Term
|
Definition
Factor 1: Somatomedian C:predominant
GH dependent
Factor : somatomedian A: fetal growth
not GH dependent |
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Term
| what aer the indirect anabolic effects? |
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Definition
| growth promoting esp of the muscle bones and organs |
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Term
| what mediates the indirect anabolic effect? |
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Definition
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Term
| what does GH directly effect? |
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Definition
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Term
| where are the hormones secreted by the NH produced? |
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Definition
| magnocellular nucli of the hypothalamus |
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Term
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Definition
| terminal swellings of the neural stalk in the neurohypophysis |
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|
Term
|
Definition
peptides that bind to preprohormones and g protiens
*carrier protien down the axons* |
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Term
| ADH is stimulated by what? |
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Definition
1. increased extracellular fluid osmolality
2. decreased blood volume
3. decreased blood pressure |
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Term
| ADH has what affects on the kidney? |
|
Definition
binds to V2 receptors on the plasma membrane. cAMP second messenger forms aquasporin II that allows water to pass through the channels\
**REDUCES FREE WATER CLEARANCE BY THE KIDNEY** |
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Term
| ADH and the vascular smooth muscle bind to what receptors? |
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Definition
V1 receptors
Second Messenger... Ca-Calmodulin and ph |
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