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        | second messenger system of body |  | Definition 
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        | endocrine systems uses __________ that are released into blood |  | Definition 
 
        | chemical messages (hormones) |  | 
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        | hormones control 5 major processes |  | Definition 
 
        | "reproduction, growth and development, mobiliazation of body defenses, maintenance of much of homeostasis, regulation of metabolism" |  | 
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        | 3 ways hormones can be classified |  | Definition 
 
        | "amino acid-based (proteins, peptides, amines), steroids (made from cholesterol), and prostaglandins (made from highly active lipids)" |  | 
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        | "hormones circulate to all organs, but a given hormone affects only certain tissue cells or organs" |  | 
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        | specific protein receptors |  | 
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        | typical effects caused by hormones (4) |  | Definition 
 
        | "(1) changes in plasma membrane permeability or electrical state; (2) symthese of proteins, such as enzymes; (3) activation or inactivation of enzymes; (4) stimulation of mitosis" |  | 
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        | steroid hormone action (5) |  | Definition 
 
        | "(1) diffuse through plasma membrane of target cells, (2) enter nucleus, (3) bind to a specific protein within nucleus, (4) (protein and steroid unit bind to specivid sites on cell's DNA, (5) then activate genes (via mRNA) that result in synthesis of new proteins" |  | 
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        | nonsteroid hormone action (4) |  | Definition 
 
        | (1) nonsteroid hormone (first messenger) binds to receptor on cell membrane but does NOT enter cell; (2) this sets off series of reactions that activates an enzyme; (3) catalyzes a reaction that produces a second messenger molecule; (4) oversees additional intracellular changes to promote a specific response (such as glycogen breakdown) |  | 
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        | negative feedback mechanisms |  | Definition 
 
        | chief way of regulating blood levels of nearly all hormons; stumulus or low hormone levels in blood triggers release of more hormone; hormone release stops once an appropriate level in blood is reached |  | 
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        | hormonal stimulus of endocrine glands |  | Definition 
 
        | endocrine glands are activated by other hormones |  | 
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        | humoral stimulus of endocrine glands |  | Definition 
 
        | changing blood levels of certain ions (i.e. calcium) stimulate hormone release |  | 
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        | neurla stimulus of endocrine glands |  | Definition 
 
        | nerve impulses stimulate hormone release (most are under control of sympathetic nervous system) |  | 
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        | major endocrine organs include…(8) |  | Definition 
 
        | "pituitary gland, thyroid gland, parathyroid gland, adrenal gland, pineal gland, thymus gland, pancreas, gonads (ovaries and testes)" |  | 
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        | location of pituitary gland |  | Definition 
 
        | hangs by stalk from hypothalamus and is protected by sphenoid bone |  | 
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        | 2 functional lobes of pituitary gland |  | Definition 
 
        | anterior pituitary (glandular tissue) and posterior pituitary (nervous tissue) |  | 
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        | which glands are ductless? |  | Definition 
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        | ductless glands that empty hormones directly into blood |  | 
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        | glands with ducts through which secretions are carried to a particular site |  | 
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        | hormones of anterior pituitary (6) |  | Definition 
 
        | "growth hormone (GH), prolactin (PRL) affect non-endocrine targets; thyroid-stimulating or thyrotropic (TSH or TH), follicle-stimulating (FSH), luteinizing (LH), and adrenocorticotropic (ACTH) are all tropic hormones (stimulate other endocrine glands)" |  | 
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        | 3 characteristics of all anterior pituitary hormones |  | Definition 
 
        | "proteins (or peptides); act throuh second-messenger systems; regulated by hormonal stimuli, mostly negative feedback" |  | 
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        | growth hormone--major effects directed to growth of skeletal muscles and long bones |  | 
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        | prolactin--stimulates and maintains milk production following childbirth |  | 
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        | adrenocorticotropic hormone--regulated endocrine activity of adrenal cortex |  | 
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        | thyroid-stimulating hormone--influences growth and activity of thyroid |  | 
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        | FSH--stimulates follicle development in ovaries and sperm development in testes; LH--trigers ovulations and stimulates testosterone production |  | 
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        | known as the master endocrine gland |  | Definition 
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        | hormones of posterior pituitary (2) |  | Definition 
 
        | oxytocin--stimulates contractions of uterus and causes milk ejection; antidiuretic (ADH) hormone--can inhibit urine production and in large amounts causes vasoconstriction leading to increased blood pressure |  | 
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        | location of thyroid gland |  | Definition 
 
        | base of throat--consists of 2 lobes and connecting isthmus |  | 
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        | thyroid gland produces 2 hormones |  | Definition 
 
        | thyroid hormone (T4--have a lot; T3--most potent) and calcitonin |  | 
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        | the body's major jetabolic hormone |  | Definition 
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        | regulates calcium balance |  | 
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        | location of parathyroid glands |  | Definition 
 
        | posterior surface of thyroid gland |  | 
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        | parathyroid glands secrete |  | Definition 
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        | functions of parathyroid hormone (3) |  | Definition 
 
        | stimulate osteoclasts to remove calcium from bone; stimulate kidneys and intestine to absorb more calcium; raise calcium level in blood |  | 
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        | location of adrenal glands |  | Definition 
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        | 2 parts to adrenal glands |  | Definition 
 
        | cortex (outer glandular region in 3 layers) and medulla (inner neural tissue region) |  | 
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        | hormones of adrenal cortex (3) |  | Definition 
 
        | "corticosteroids (mineralocorticoids, glucocorticoids, sex hormones)" |  | 
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        | "produced in outer adrenal cortex and regulate mineral content in blood, water  and electorlyte balance (target organ is kidney)" |  | 
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        | produced in middle layer of adrenal cortex and promote normal cell metabolism (released in response to increased blood levels of ACTH) |  | 
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        | produced in inner layer of adrenal cortex--androgens (male) and some estrogen (femail) |  | 
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        | hormones of adrenal medulla |  | Definition 
 
        | catecholamines (epinephrine and norepinephrine)--prepare body to deal with short-term stress |  | 
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        | best0hidden endocrine glands in body |  | Definition 
 
        | pancreatic islets (islets of Langerhans) |  | 
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        | exocrine (enzyme-producing) part of pancreas acts as part of the… |  | Definition 
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        | hormones produced by islets of pancreas (2) |  | Definition 
 
        | insulin (allows glucose to cross plasma membranes into cells from beta cells) and glucagon (allows glucose to enter blood from alpha cells) |  | 
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        | function of insulin and glucagon |  | Definition 
 
        | antagonists that maintain blood sugar homeostasis |  | 
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        | found on third ventricle of brain |  | 
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        | secretes melatonin (helps establish body's wake/sleep cycles) |  | 
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        | produces thymosin which matures some types of WBCs and important in developing the immune system |  | 
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        | estrogens and progesterone |  | 
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        | "(produced by Graafian follicles or placenta) stimulates development of secondary female characteristics; matures female reproductive organs, helps perpare uterus to receive fertilized egg; helps maintain pregnancy; prepares breasts to produce milk" |  | 
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        | progesterone functions (2) |  | Definition 
 
        | (produces by corpus luteum) acts with estrogen to bring about menstrual cycle and helps in implantation of embryo in uterus |  | 
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        | produces several androgens; testosterone is most important |  | 
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        | testosterone functions (3) |  | Definition 
 
        | responsible for adult male secondary sex characteristics; promotes growth and maturation of male reproductive system; required for sperm cell production |  | 
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        | other hormone-producing tissues and organs (4) |  | Definition 
 
        | "parts of small intestine, parts of stomach, kidneys, heart" |  | 
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        | endocrine functions of placenta (3) |  | Definition 
 
        | "produces hormones to maintain pregnancy; some hormones play part in delivery of baby; produces HCG in addition to estrogen, progesterone, and other hormones" |  | 
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