Term
| 1. 4 outcomes of acute inflammation. |
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Definition
| 1) COMPLETE RESOLUTION, 2) HEALING BY FIBROSIS/ORGANIZATION, 3) ABSCESS FORMATION, 4) CHRONIC INFLAMMATION |
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Term
| 2. Abscess formation generally leads to _____ necrosis. |
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Definition
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Term
| 3. Liquefactive necrosis is generally causes by _____ infections. |
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Definition
| BACTERIAL (STREPTO AND STAPHYLOCOCCUS) |
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Term
| 4. _____ is inflammation of prolonged duration (weeks, months, years or life) in which active inflammation, tissue destruction, and attempts at healing are all proceeding simultaneously. |
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Definition
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Term
| 5. 3 causes of chronic inflammation that can arise without a pre-existing acute inflammatory component. |
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Definition
| 1) PERSISTENT MICROBACTERIUM TUBERCULOSIS, 2) PROLONGED EXPOSURE TO EXOGENOUS OR ENDOGENOUS TOXIC AGENTS, 3) AUTOIMMUNE DISEASE |
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Term
| 6. The predominant cell of granulomatous inflammation is the _____, which possesses a modified epithelial (epithelioid) like appearance. |
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Definition
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Term
| 7. 5 cell types involved in granulomatous inflammation. |
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Definition
| 1) MULTINUCLEATED GIANT CELLS, 2) LYMPHOCYTES, 3) NECROSIS, 4) FIBROBLASTS, 5) ACTIVATED MACROPHAGES |
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Term
| 8. _____ is a focal area of granulomatous inflammation consisting of a central zone of necrosis surrounded by microscopic aggregates of epithelioid cells, lymphocytes, and fibroblasts. |
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Definition
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Term
| 9. 4 general causes of granuloma formation. |
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Definition
| 1) IMMUNE REACTIONS, 2) CHRONIC IRRITATION, 3) UNDIGESTIBLE FOREIGN MATERIAL, 4) UNKNOWN CAUSES |
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Term
| 10. 6 specific causes of granulomatous inflammation. |
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Definition
| 1) TB, 2) LEPROSY, 3) SYPHILIS, 4) SARCOIDOSIS, 5) FUNGAL INFECTION, 6) SUTURE |
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Term
| 11. 4 morphologic patters in acute and chronic inflammation. |
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Definition
| 1) SEROUS INFLAMMATION, 2) FIBRINOUS INFLAMMATION, 3) SUPPURATIVE INFLAMMATION, 4) ULCERATION |
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Term
| 12. _____ inflammation is thin/watery inflammation. |
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Definition
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Term
| 13. _____ inflammation is thick gooey inflammation that has a lot of protein. |
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Definition
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Term
| 14. _____ is when we separate the pericardium and myocardium and we see a stringy like complexion. |
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Definition
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Term
| 15. _____ inflammation occurs in pyogenic infections. |
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Definition
| SUPPURATIVE (PURULENT) INFLAMMATION |
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Term
| 16. _____ is a condition that has suppurative/purulent inflammation. |
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Definition
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Term
| 17. _____ inflammation is erosion of the epithelium lining. |
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Definition
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Term
| 18. _____ is an example of ulceration. |
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Definition
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Term
| 19. Repair mechanisms following acute and chronic inflammation involve these 4 components. |
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Definition
| 1) ANGIOGENESIS, 2) MIGRATION AND PROLIFERATION OF FIBROBLASTS, 3) DEPOSITION OF EXTRACELLUR MATRIX, 4) REMODELING OF CONNECTIVE TISSUE |
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Term
| 20. _____ is migration and proliferation of endothelial cells. |
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Definition
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Term
| 21. _____ cells are responsible for secreting extracellular matrix (scar tissue). |
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Definition
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Term
| 22. Fibroblasts form scar tissue by laying down _____. |
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Definition
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Term
| 23. _____ are cells responsible for having a contractile ability that aids in helping the contracture of a wound minimizing scar formation. |
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Definition
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Term
| 24. The older the scar the more _____ it is. |
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Definition
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Term
| 25. _____ is the hallmark tissue of early healing by fibrosis. |
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Definition
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Term
| 26. _____ is the earliest form of scarring (pre-scar). |
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Definition
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Term
| 27. 4 components of granulation tissue. |
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Definition
| 1) PROLIFERATING SMALL CAPILLARIES, 2) PROLIFERATING FIBROBLASTS/MYOFIBROBLASTS, 3) EXTRACELLULAR FLUID, 4) MACROPHAGES |
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Term
| 28. 4 functions of granulation tissue. |
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Definition
| 1) FILLS IN TISSUE GAPS, 2) REMOVES DEAD CELL DEBRIS, 3) AIDS IN WOUND CONTRACTION, 4) FORM EARLY PRE-SCARS |
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Term
| 29. _____ is healing by primary union/intention. |
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Definition
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Term
| 30. 7 steps in the mechanism of skin-wound healing by primary union/intention. |
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Definition
| 1) BLOOD CLOT FILLS INCISIONAL SPACE, 2) NUTROPHL INFILTRATION, 3) EPITHELIAL CONTINUITY RESTORED, 4) MACROPHAGE INFILTRATION, 5) GRANULATION TISSUE FILLS SPACE, 6) PROGRESSIVE COLLAGENIZATION, 7) REMODELING |
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Term
| 31. 4 steps in the mechanism of skin-wound healing by secondary union/intention. |
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Definition
| 1) LARGE AMOUNTS OF GRANULATION TISSUE ARE REQUIRED, 2) INFLAMMATORY REACTION IS MORE PROLONGED, 3) MORE DEBRIS AND INFLAMMATORY EXUDATE, 4) MORE PRONOUNCED SCAR FORMATION |
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Term
| 32. 7 local factors which influence wound healing. |
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Definition
| 1) TYPE, 2) SIZE, 3) LOCATION, 4) VASCULAR SUPPLY, 5) INFECTION, 6) MOVEMENT |
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Term
| 33. 3 systemic factors which influence wound healing. |
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Definition
| 1) CIRCULATORY STATUS, 2) INFECTION, 3) MALNUTRITION |
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Term
| 34. _____ is a complication of normal wound healing when there is excessive granulation tissue. |
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Definition
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Term
| 35. _____ is a complication of normal wound healing when there is hypertrophic scar formation/excessive collagen deposition. |
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Definition
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Term
| 36. _____ is a complication of normal wound healing caused by mechanical stress, usually seen in abdominal and open heart surgery. |
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Definition
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Term
| 37. _____ is a complication of normal wound healing when there is excessive wound contraction caused by excessive myo-fibroblast activity. |
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Definition
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