Term
| Eczema is characterized histologically by intercellular edema called ___. |
|
Definition
|
|
Term
|
Definition
- Acute- vesicles
- Subacute- papules
- Chronic lichenification |
|
|
Term
| Essential dermatitis is a ___ ___ diagnosis in which the underlying ___ cannot be found (allergen/irritant) and it fits no defined ____ such as atopic or seborrheic dermatitis. |
|
Definition
- nonspecific idiopathic
- cause
- pattern |
|
|
Term
| Dyshydrotic eczema aka ___ presents as vesicles on ___, ___, and sides of ___. It is described as ___ __. |
|
Definition
- pompholyx
- palms, soles, and sides of digits
- tapioca pudding |
|
|
Term
| __ __ is generalized dermatitis following localized acute dermatitis. |
|
Definition
|
|
Term
| ___ __ occurs in the elderly. It is common on the lower extremities in the winter due to low humidity. |
|
Definition
|
|
Term
| __ ___ presents as oval patches. |
|
Definition
|
|
Term
| Therapy for eczema and dermatitis: |
|
Definition
- topical corticosteroids (mainstay)
- topical immunomodulators (Pimecrolimus and Tacrolimus)these are good for face and intertigenous areas, do not cause atrophy
- astringent dressings for weeping eczema
- antihistamines
- antibiotics for secondary bacterial infections |
|
|
Term
| Contact dermatitis is either __ or __. |
|
Definition
|
|
Term
| 70% of contact dermatitis is due to an ___ that has a direct toxic effect (chemicals, acids, alkaloids, water). 30% of contact dermatitis is due to ___, which is a type IV hypersenstivity reaction (nickel, poison ivy/oak/sumac, rubber compounds, medications) . |
|
Definition
|
|
Term
| Lady that is OCD and washes her hands way too much will get __ ___ __. |
|
Definition
| irritant contact dermatitis |
|
|
Term
| linear streaks of papules and vesicles with indurated plaques and patches. |
|
Definition
| allergic contact dermatitis (poison ivy) |
|
|
Term
| Smoke of burning plants can result in confluent severe dermatitis of exposed skin (poison ivy). |
|
Definition
|
|
Term
| Diaper rash is a form of __ __ __, it spares the __ __. |
|
Definition
- irritant contact dermatitis
- spares the skin folds |
|
|
Term
| With allergic contact dermatitis, short term you can treat with topical corticosteroid but in the long term... |
|
Definition
| must discontinue exposure to allergen (nickel) |
|
|
Term
| Treatment for severe and generalized contact dermatitis: |
|
Definition
| 40 mg Prednisone daily for 10 days |
|
|
Term
| Treatment for milder dermatitis: |
|
Definition
| topical steroids/topical immunomodulators with antihistamines as needed |
|
|
Term
| 6 types of Eczematous Eruptions: |
|
Definition
- Essential dermatitis
- Contact dermatitis
- Atopic dermatitis
- Seborrheic dermatitis
- Stasis dermatitis
- Lichen simplex chronicus |
|
|
Term
| Atopic dermatitis diagnostic criteria: |
|
Definition
- Pruritus
- typical morphology and distribution
- flexural lichenification in adults and older children
- facial and extensor papulovesicles in infancy
- chronic-relapsing course
- personal or family history of atopic disease (allergic rhinitis, asthma, atopic dermatitis) |
|
|
Term
| Atopic dermatitis usually starts in __ ___. |
|
Definition
| young children (2 months - 5 years) |
|
|
Term
| ___ is the clinical hallmark of chronic atopic dermatitis. |
|
Definition
|
|
Term
| Normal distribution for atopic dermatitis in children: |
|
Definition
- face/head
- hands
- groin
- front of knees
- feet |
|
|
Term
| Normal distribution for atopic dermatitis in older children and adults: |
|
Definition
- forehead, lower face
- upper chest
- neck
- back of hands
- wrists
- antecubital and popliteal fossase |
|
|
Term
| atopic dermatitis therapy: |
|
Definition
- moisturizers/bath oil
- topical steroids/immune modulators
- mild soaps
- treatment of any superimposed bacterial infection
severe cases: short course of cyclosporine
(with this condition you don't have normal lipid layer in epidermis, so try to replace it with lotions)
chronic relapsing condition, but many outgrow it by late adolescence |
|
|
Term
| __ __ is a chronic superficial inflammatory process affecting hairy regions of the body, espcially the __, __, and __. |
|
Definition
- Seborrheic dermatitis
- scalp, eyebrows, and face |
|
|
Term
| Seborrheic dermatitis is caused by ___ ___ aka ___ ___. It is associated with Parkinson's disease and AIDs. |
|
Definition
| - Pityrosporum Ovale aka Malassezia globosa |
|
|
Term
| Seborrheic dermatitis is characterized by patches and plaques with __ __, mild to moderate __, and a __ ___ ___. |
|
Definition
- indistinct margins
- erythema
- yellowish, greasy scaling |
|
|
Term
| atopic dermatitis therapy: |
|
Definition
- moisturizers/bath oil
- topical steroids/immune modulators
- mild soaps
- treatment of any superimposed bacterial infection
severe cases: short course of cyclosporine
(with this condition you don't have normal lipid layer in epidermis, so try to replace it with lotions)
chronic relapsing condition, but many outgrow it by late adolescents |
|
|
Term
| __ __ is a chronic superficial inflammatory process affecting hairy regions of the body, espcially the __, __, and __. |
|
Definition
- Seborrheic dermatitis
- scalp, eyebrows, and face |
|
|
Term
| Seborrheic dermatitis is characterized by plaques and patches with __ __, mild to moderate ___, and a __ __ __. |
|
Definition
- indistinct borders
- erythema
- yellowish greasy scaling |
|
|
Term
| Distribution of Seborrheic dermatitis: |
|
Definition
- scalp
- eyebrows
- eyelids
- nasolabial creases
- ears
- chest
- intertriginous areas
- axilla
- groin
- buttocks
- inframammary folds |
|
|
Term
| ___ is the mildest form of seborrhiec dermatitis in which one sees fine white scales without erythema or pruritis. |
|
Definition
|
|
Term
| Seborrheic dermatitis therapy: |
|
Definition
- nonprescription and antiseborrheic shampoos containing zinc pyrithione (head and shoulders), selenium sulfide (head and shoulders intensive treatment) or Ketoconazole (must be left on skin for 3-5 minutes before rinsing)
- topical steroids/immune modulators
(avoid high potency steroids on face)
( in lecture he said treat with the topical, then maitenance with antifungal) |
|
|
Term
| __ __ is an eczematous eruption of the lower legs secondary to peripheral venous disease. |
|
Definition
Stasis dermatitis
- Venous incompetence causes increased hydrostatic pressure and capillary damage leading to edema, inflammation, fibrin deposition, tissue hypoxia and overlying skin change. |
|
|
Term
| With stasis dermatitis you will often see __ __ and/or __ __. The involved skin has __ ___ , __ __, petechiae, ___ __, scaling, and/or weeping. |
|
Definition
- varicose veins or pitting edema
- BROWNISH HYPERPIGMENTATION
- DULL ERYTHEMA
- THICKENED SKIN |
|
|
Term
| Stasis dermatitis therapy: |
|
Definition
- prevent venous stasis and edema: supportive hose, compression stockings, lose weight, elevate legs above heart, topical steroids
- can lead to leg ulceration if uncontrolled
- beware of causing allergy with use of topical corticosteroids |
|
|
Term
| Lichen simplex chronicus is aka ___. It is a chronic eczematous eruption of skin that results from scratching. Can be located anywhere within fingers reach, but common on __ of males. Produces a chronic itch-scratch cycle. |
|
Definition
- Neurodermatitis
- scrotum |
|
|
Term
| ___ ___ are linear "dug out" lesions everywhere, except the mid-back, where typically neurotic women cannot reach. |
|
Definition
|
|
Term
| __ ___ are self inflicted injuries for secondary gain. They are often ulcerated and have __ or ___ outlines. |
|
Definition
- Factitious dermatitis
- linear or geometric |
|
|
Term
| __ __ __ occurs when a patient is convinced that they are harboring parasites. They often bring in specimens to prove their case. Usually excoriations and ulcerations are seen secondary to picking. |
|
Definition
|
|
Term
| Darier's Disease aka __ ___ is an autosomal ___ ___. This presents as tan, pink, brown rough feeling ___ coalescing into __ __ on seborrheic areas like the __, __, __, and __. These plaques often become secondarily infected. |
|
Definition
- keratosis follicularis
- dominant genodermatosis
- papules
- large plaques
- scalp, face, neck, trunk |
|
|
Term
| With Darier's disease the papules and plaques __ ___ __, they may __, and there is a __ __. A __ is done to confirm the diagnosis. |
|
Definition
- never go away
- smell
- family history
- biopsy |
|
|
Term
| With Darier's disease, the skin biopsy would show __ ___ __ with __ ___. |
|
Definition
- epidermal suprabasalar clefts
- acantholytic keratinocytes |
|
|
Term
| Glucagonoma Syndrome aka ___ __ ___ is a multisystem disorder caused by a __ __ of the __ __ cell. |
|
Definition
- Necrolytic Migratory Erythema
- pancreatic tumor of the islet alpha cell |
|
|
Term
| With Glucagonoma Syndrome/Necrolytic Migratory Erythema you would see periorificial, acral, and flexural erythematous scaling __, __, and __ with associated ___. A skin biopsy would show __ __ __. These people are really sick (weight loss, anemia, diarrhea, diabetes) |
|
Definition
- papules, patches, and plaques
- glossitis
- superficial epidermal necrosis |
|
|
Term
| Langerhans cell histiocytosis formerly known as __ __ is a __ of the Langerhans cells. . |
|
Definition
- Histiocytosis X
- neoplasm |
|
|
Term
| Langerhan cell histiocytosis forms (3): |
|
Definition
- Acute disseminated (Letterer-Siwe Disease)
- Chronic multifocal (Hand-Schuller-Christian disease)
- Localized (Eosinophilic granuloma) |
|
|
Term
| Acute disseminated histiocytosis presents in ___ as ___ __ __. See pink, sometimes hemorrhagic, papules and scaling with slightly eroded patches. Skin biopsy shows proliferation of __ __, stain for __ __ and see __ __ on electron microscopy. |
|
Definition
- infancy
- recalcitrant diaper rash
- Langerhan cells
- S-100
- Birbeck granules |
|
|
Term
| With lichen sclerosis you will see ivory white __ ___, often in the __ area. Treat early to prevent scarring. |
|
Definition
- atrophic patches
- genital area |
|
|
Term
| Pemphigus Foliaceus is a very rare ___ disease similar to pemphigus vulgaris. You will see erythematous scaling with some crusting with ___ __ and ___. No __ __ is seen. Dx with skin biopsy and direct immunoflourescence. |
|
Definition
- flaccid bullae and erosions
- NO mucosal involvement is seen |
|
|
Term
| Wiskott-Aldrich syndrome is a rare __ __ ___ disorder. You will see diffuse erythematous __ and ___ with ___. These kids have recurrent __ __ b/c they have impaired __ __, decreased IgM, increased __ and __, ___, and platelet dysfunction. |
|
Definition
- x-linked recessive
- papules and macules with petechia
- recurrent severe infections
- impaired cell immunity
- increased IgE and IgA
- thrombocytopenia |
|
|
Term
| Inherited zinc deficiency is called: |
|
Definition
| Acrodermatitis Enteropathica |
|
|
Term
| With zinc deficiency, you will see ___, ___, and __ dermatitis with ___. Confirm diagnosis with low serum zinc level. |
|
Definition
- perioral, genital, and acral
- diarrhea |
|
|
Term
| Types of idiopahtic eczema: |
|
Definition
- Dishidrotic
- Autosensitization aka Id eruption
- Xerotic
- Nummular |
|
|
