| Term 
 
        | Olfactory Nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = I Afferent component = SA, smell, taste, vision, hearing, balance afferents
 Efferent component = NONE
 Exit from skull =Cribriform plate of ethmoid bone
 Function = Smell
 
 LESION: Loss of smell (anosmia), injury to cribriform plate; congenital absence.
 *end up synapsing with secondary neurons in olfactory bulbs
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        | Term 
 
        | Optic Nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = II Afferent component = Smell taste, vision hearing, balance afferent
 Efferent component = NONE
 Exit from skull = Optic canal
 Function = Vision
 
 *return information to brain from photoreceptors in retina
 
 LESION: Blindness/visual field abnormalities, loss of pupillary constriction.  Direct trauam to orbit, disruption of optic pathway.
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        |  | 
        
        | Term 
 
        | Oculomotor nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = III Afferent component = NONE
 Efferent component = General somatic efferent, General visceral efferent
 Exit from skull =Superior orbital fissure
 Function = GSE: 1) levator palpaebrae superioris, 2) rectii muscle (except lateral), 3) inferior oblique muscles.  GVE - innervates 1) sphincter pupillae for pupillary constriction 2) ciliary muscles for accomodation of the lens for near vision
 
 *GVE fibers are parasympathetic! Accomodation for near vision, pupillary constriction
 
 *LESION: Dilated pupil, ptosis, loss of normal pupillary reflex, eye moves down inferiorly and laterally.  Caused by pressure from aneurysm from posterior communicating, posterior cerebral, or superior cerebellar artery, pressure from a herniating cerebral uncus, cavernous sinus mass, or thrombosis
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        |  | 
        
        | Term 
 
        | Trochlear Nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = IV Afferent component = NONE
 Efferent component = GSE
 Exit from skull = superior orbital fissure
 Function = Innervates superior oblique muscle
 
 *The only cranial nerve to exit from posterior surface of brainstem
 
 LESION: Inability to look down and in. Injury along course of nerve around brainstem; orbital fracture.
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        |  | 
        
        | Term 
 
        | Trigeminal Nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = V Afferent component = GSA
 Efferent component = Branchial efferent (motor innervation to skeletal muscles from pharyngeal arch mesoderm)
 Exit from skull = see
 Function = see
 
 *Be - innervates temporalis, masseter, medial and lateral pterygoids, tensor tympani, tensor veli palantini, anterior blely of digastric, and mylohyoid muscles
 
 LESION: Losso f sensation/pain in regions; loss of motored mastication. Problem typically in region of trigeminal ganglion.
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        |  | 
        
        | Term 
 
        | Ophthalmic Division CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = V-1 Afferent component = GSA
 Efferent component = Branchial efferent
 Exit from skull = superior orbital fissure
 Function = eyes, conjuctiva, orbital contents, nasal cavity, frontal sinus, ethmoid sinus, upper eyelid, dorsum of nose, anterior part of scalp
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        |  | 
        
        | Term 
 
        | Maxillary division CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = V-2 Afferent component = GSA
 Efferent component = BE
 Exit from skull = foramen rotundum, enters pterygopalatine fossa
 Function = dura in anterior and middle cranial fossae, nasopharynx, palate, nasal cavity, upper teeth, maxillary sinus, skin covering the side of hte nose, lower eyelid, cheek, upper lip
 |  | 
        |  | 
        
        | Term 
 
        | Mandibular division: CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = V-3 Afferent component = GSA (general somatic afferent = perception of touch, pain temperature)
 Efferent component = BE
 Exit from skull = foramen ovale
 Function = skin of lower face, cheek, lower lip, ear, external acoustic meatus, temporal fossa, anterior 2/3 of tongue, lower teeth, mastoid air cells, mucuous membranes of cheek, mandible, dura in middle cranial fossa
 
 *once it leaves foramen ovale, unites with sensory component of mandibular nerve (V3) outside of skull; only division of trigeminal nerve htat contains a motor component (muscles of mastication (temporalis, massseter, medial/lateral pterygoids, tnesor tympani, tensor veli palatini, digastric anterior belly, and mylohyoid)
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        |  | 
        
        | Term 
 
        | Abducent Nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = VI Afferent component = NONE
 Efferent component = GSE
 Exit from skull = Superior orbital fissure
 Function = Innervates lateral rectus muscle
 
 *arises from brainstem between pons and medulla, passes forward, enters/crosses cavernous sinus just interolateral to internal carotid artery
 
 LESION: Inability to lateral eye movement.  Example, brain lesion or cavernous sinus lesion extending onto the orbit.
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        |  | 
        
        | Term 
 
        | Facial nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = VII Afferent component = GSA (perception of touch, pain, temperature), SA (smell, taste, vision, hearing, balance)
 Efferent component = GVE, BE
 Exit from skull = Internal acoustic meatus
 Function = GSA - sensory from external acoustic meatus, skin posterior ear. SA - taste from anterior 2/3rd of tongue. GVE - motor innervates lacrimal gland, submandibular and sublingual salivary glands, and mucous membranes of nasal cavity, and hard and soft palates. BE - motor innervates muscesl of face (facial expression) and scalp derived from 2nd paryngeal arch, and stapedius, posteriro belly of digastric, stylohyoid muscles
 
 Paralsysi fof faicla muscles below eye.  Abnormal taste sensation of tongue, dry conjuctivae.  Caused by damage to branches within the parotid gland.  Injury to temporal bone; viral inflammation of nerve.  Or brainstem injury.
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        |  | 
        
        | Term 
 
        | Vestibulocochlear nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = VIII Afferent component = SA
 Efferent component = NONE
 Exit from skull = Internal acoustic meatus
 Function = Vestibular division - balance, Cochlear division - hearing
 
 *two divisions combine into single nerve seen in posterior cranial fossa within the substance of the petrous part of the temporal bone
 
 LESION: Progressive unilateral hearing loss and tinnitus (ringing in ear).  Example: tumor at cerebellopontine angle.
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        |  | 
        
        | Term 
 
        | Glossopharyngeal nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = IX Afferent component = GVA, SA
 Efferent component = GVE, BE
 Exit from skull = Jugular foramen
 Function = GVA - sensory from carotid body and sinus, posterior one-third of tongue, palatine tonsils, upper pharynx, and mucosa of middle ear and pharyngotympanic tube.  SA - taste from posterior 1/3 of tongue.  GVE - innervates parotid salivary gland.  BE - innervates stylopharyngeus muscle.
 
 *The glossopharyngeal nerve arises as several rootlets on the anterolateral surface of the upper medulla oblongata.  The rootlets cross the posterior cranial fossa and enter jugular foramen; within foramen, merge to form glossopharyngeal nerve.  WIthin or immediately outside the jugular foramen are two ganglia (superior/inferior ganglia), which contain the cell bodies of the sensory neurons in the glossopharyngeal nerve (IX).
 
 LESION: Loss of taste to posteriro 1/3rd of tongue, sensation of soft palate. Due to brainstem lesion/penetrating neck injury.
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        |  | 
        
        | Term 
 
        | Tympanic Nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = branching from glosspharyngeal nerve within or immediately outside jugular foramen, re-etners temporal bone, enters middle eary cavity, and partiicpates in formation of tympanic plexus.  Also contributes GVE fibers, leave tympanic plexus in lesser petrosal nerve, small nerve that exits the tmeporal bone, descends through foramen ovale to exit the cranial cavity carrying pregnaglionic parasympathetic fibers to otic ganglion. |  | 
        |  | 
        
        | Term 
 
        | Vagus Nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = X Afferent component = GSA, GVA, SA
 Efferent component = GVE, BE
 Exit from skull = Jugular foramen
 Function = GSA - sensory from skin posterior to ear and external acoustic meatus, and dura in posterior cranial ossa. GVA - sensory from aortic body chemoreceptors and aortic arch baroreceptors, mucous membranes of pharynx, larynx, esophagus, bronchi, lungs, heart, and abdominal viscera of the foregut and midgut. SA - taste from epiglottis.  GVE - innervates smooth muscle and glands in the pharynx, larynx, thoracic viscera, and abdominal viscrea of foregut and midgut. BE - innervates one tongue muscle (palatoglossus), muscles of soft palate (except tensor veli palatini), pharynx (except stylopharyngeus), and larynx
 
 *Within or immediately outside the jugular foramen are two ganglia, sueprior/inferior ganglia, contain cell bodies of sensory neurons in vagus nerve
 
 LESION: Soft palate deviation with deviation of uvula to the normal side; vocal cord paralysis.  Due to brainstem lesion; penetrating neck injury.
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        |  | 
        
        | Term 
 
        | Accessory Nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = XI Afferent component = NONE
 Efferent component = BE
 Exit from skull = Jugular foramen
 Function = Innervates sternocleidomastoid and trapezius muscles
 
 *Crouse: arise from motor neurons in upper five segments of cervical spinal cord. These fibers leave hte lateral surface, as they ascend, enter cranial cavity through foramen magnum.  The accessory nerve (XI) continues through the posterior cranial fossa and exits through the jugular foramen.
 
 LESION: paralysis of sternocleidomastoid and trapezius muscles.  Ex) penetrating injury to hte posterior triangle of the neck.
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        |  | 
        
        | Term 
 
        | Hypoglossal nerve CN # =
 Afferent component =
 Efferent component =
 Exit from skull =
 Function =
 |  | Definition 
 
        | CN # = XII Afferent component = NONE
 Efferent component = GSE
 Exit from skull = Hypoglossal canal
 Function = Innervates hypoglossus, genioglossus, and styloglossus muscles and all intrinsic muscles of the tongue
 
 LESION: Atrophy of tongue, speech disturbance.  Penetrating injury to neck and skull base pathology
 
 LESION: atrophy of ipsilateral muscles of tongue, and deviation towards affected side; speech disturbance.
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