Term
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Definition
| Excitatory neurotransmitter |
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Term
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Definition
Class of "dirty" sedative drugs - block many different receptors and so overall decrease in CNS function
e.g. Acepromazine |
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Term
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Definition
Class of "dirty" sedative drugs - block many different receptors and so overall decrease in CNS function
e.g. Haloperidol |
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Term
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Definition
Class of sedatives - activate alpha-2-R (presynaptic) so inhibit NA release
e.g. Xylazine, Medetomidine |
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Term
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Definition
Class of anxiolytic which can be used as weak sedatives - allosteric modulator of GABA-A-R so enhances GABA binding and enhances inhibition (incr. channel openings)
e.g. Diazepam |
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Term
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Definition
Dissociative anaesthetic - blocks NMDA-R, preventing glutamate binding
-Induces sedation, immobility and analgesia, with no CV or resp. depression, but psychic disturbances and invol mvmts.
-also used to induce GA |
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Term
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Definition
a phenothiazine: a "dirty" sedative drug - blocks many different receptors and so overall decrease in CNS function
-used for sedation, often as a pre-med |
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Term
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Definition
an alpha-2-agonist - causes sedation, analgesia, muscle relaxation.
Used in D+C, H |
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Term
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Definition
an alpha-2-agonist- causes sedation, analgesia, muscle relaxation.
Used in D+C (not H) |
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Term
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Definition
an alpha-2-agonist - causes sedation, analgesia, muscle relaxation.
Used in H (not D+C) |
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Term
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Definition
alpha-2 agonist antagonists
i.e. reverses the effects of alpha-2 aginist e.g. reversal of xylazine |
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Term
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Definition
A BZD: an allosteric modulator of GABA-A-R so enhances GABA binding and enhaces inhibition.
used to calm D+C |
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Term
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Definition
-General anaesthetic - used to induce - can't be used repeatedly
-A barbiturate - allosteric modulator of GABA-A-R, so enhances GABA action and enhances inhibtion (prolongs channel opening) |
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Term
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Definition
Injectable general anaesthetics, used for induction
-No CV or resp depression, rapid metabolism and high TI
BUT excitement |
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Term
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Definition
A neurosteroid, used as injectable GA to induce.
-Little resp depression, rapid biotransformation and high TI
BUT excitement and CV depression, contraindicated in dogs (histamine release) |
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Term
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Definition
Injectable general anaesthetics, used for induction
-rapid induction and metabolism, non-cumulative, non-irritant, little excitement |
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Term
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Definition
| Used as a adjunct for GA - not sufficiently potent alone |
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Term
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Definition
| Volative liquids used for maintenance of GA via inhlation |
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Term
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Definition
| v. potent opiod, used for LA (must carry diprenorphine) |
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Term
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Definition
| potent opiod, good for acute pain |
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Term
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Definition
| Opiod - μ-partial agonist. Very long duration |
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Term
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Definition
| Opiod - κ-agonist Short acting so used as sedative |
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Term
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Definition
Opiod - gold standard
NB: can be metabolised to active metabolite |
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Term
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Definition
| Opiod, equal potency to morphine. Long acting and orally active (morphine has low oral bioavailibility). Activates many Rs so much sedation / depression |
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Term
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Definition
| Opiod- weak μ-agonist -good at suppressing pain |
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Term
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Definition
| opiod antagonist, short acting |
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Term
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Definition
| Potent opiod antagonist - must always carry with etorphine |
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Term
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Definition
Local anaesthetic
ester bond so short half life, pKa=8.98 so poor tissue penetration |
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Term
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Definition
Most widely used local anaesthetic
-amide group so long half-life
pKA=8.0 so good tissue penetration |
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Term
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Definition
Atypical, weak local anaesthetic - used for topical pain relief
-no amine group so 100% unionised - works by hydrophobic pathway |
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