| Term 
 
        | What is the flow of blood through? |  | Definition 
 
        | a closed circuit of hollow tubes (vessels) 2 Circuits
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        | Term 
 
        | What are the two circuits called? |  | Definition 
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        | Term 
 
        | What are the functions of the blood? |  | Definition 
 
        | carries respiratory gases, nutritents, and hormones. helps regulate temperature
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        | Term 
 
        | What is the blood volumes? |  | Definition 
 
        | males: 5-6L Females: 4-5L
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        | Term 
 
        | What components make up blood? |  | Definition 
 
        | cellular and liquid components |  | 
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        | Term 
 
        | Blood is a specialized -- |  | Definition 
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        | Term 
 
        | What are the formed elements in blood, and what is the fluid portion? What is serum? |  | Definition 
 
        | blood cells are the formed elements plasma is the fluid portion
 Serum=plasma minus clotting proteins
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        | Term 
 | Definition 
 
        | percent red blood cells Males: 47%
 Females 42%
 Both +or- 5%
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        | Term 
 
        | What is blood plasma? How much of whole blood is it? |  | Definition 
 
        | Straw-colored sticky fluid portion of blood 55% of whole blood
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        | Term 
 
        | how much of blood plasma is water? |  | Definition 
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        | Term 
 
        | What does blood plasma contain? |  | Definition 
 
        | ions nutrients wastes and proteins |  | 
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        | Term 
 
        | What are the 3 main proteins in blood plasma? |  | Definition 
 
        | albumin globulins
 fibrnogen
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        | Term 
 | Definition 
 
        | most abundant maintains osmotic pressure
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        | Term 
 | Definition 
 
        | many varieties 1. alpha and beta globulins: transport metal ions (iron copper) some transport lipids, incluiding lipid hormones
 2. Gamma globulins: immunoglobulins (antibodies)
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        | Term 
 | Definition 
 
        | converted to fibrin- major component of blood clot |  | 
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        | Term 
 | Definition 
 
        | Erythrocytes leukocytes
 platelets
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        | Term 
 
        | How does the staining of blood cells turn out? |  | Definition 
 
        | Acidic dye-eosin, stains pink Basic dye- hematoylin or methylene blue- stains blue and purple
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        | Term 
 
        | What does seperating blood components create? |  | Definition 
 
        | three layers: 1. RBCs
 2. Buffy coat
 3. Plasma
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        | Term 
 
        | What are Erythrocytes? transport? diameter? Shape? Life span? Originate?  |  | Definition 
 
        | red blood cells (RBC) Oxygen transporting cells (7.5 micromettees diameter) Biconcave shape 30% more surface area Live 100-120 days Originate in bone marrow |  | 
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        | Term 
 
        | What is the oxygen carrying protein? |  | Definition 
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        | Term 
 
        | What is the most numerous of the formed elements? |  | Definition 
 
        | RBC, erthrocytes Femals have 4.3-5.3 million cells/cubic millimete of blood
 Males have 5.2-5.8 million
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        | Term 
 
        | What does a mature Erythrocyte/RBC have? |  | Definition 
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        | Term 
 | Definition 
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        | Term 
 
        | Leukocytes/WBCs size and function |  | Definition 
 
        | 4800-11000/cubic millimeter Protect body from infectious microorganisms, function outside the bloodstream in loose connective tissue
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        | Term 
 | Definition 
 
        | circulating leukocytes leave the capillaries by squeezing between endothelial cells |  | 
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        | Term 
 
        | What are the types of leukocytes? |  | Definition 
 
        | granulocytes: contain enzyme filled vessicles (look like small granules) in cytoplasm Agranulocytes: lack vesicles
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        | Term 
 
        | When leukocytes is leaving the bloodstream per diapedsis, what is the loss of formed elements through ruptured vessel called? |  | Definition 
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        | Term 
 
        | What are the types of granulocytes? |  | Definition 
 
        | 1. neutrophils 2. Eosinophiles
 3. Basophils
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        | Term 
 | Definition 
 
        | most numerous WBC -phagocytize bacteria
 -granules contain enzymes to destroy bacteria
 -Nucleus is multi-lobed (2-6 lobes)
 --aka polymorphonucleated granulocytes PMNs
 --Immature cells dont have multi-lobed nuclei=band cells
 -Granules pick up acidic and basic stains, appear neutral colored -nuceli stain purple/blue
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        | Term 
 | Definition 
 
        | compose 1-4% of all WBC -granules stained by eosin )pink)
 Plays a role in:
 1. allergic reactions
 2. parasitic infections
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        |  | 
        
        | Term 
 | Definition 
 
        | .5% of all leukocytes (least common) -nucleus usually 2 lobes
 -Granules stained by basic dyes (purp)
 -Granules secrete histamine
 -function in inflammation mediation- similar to mast cells in function
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        | Term 
 
        | What are the types of Agranulocytes? |  | Definition 
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        | Term 
 | Definition 
 
        | compose of 20-45% WBC Most important cell in immune sys
 Nucleus is dark purple, cytoplasm looks smooth
 -efective in fighting infectious organisms
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        | Term 
 
        | What are the classes of lymphocytes? |  | Definition 
 
        | Tcells-attack foreign cells directly B cells-multiply to become plasma cells and secrete antibodies
 -Act against a specific foreign molecules (antigen)
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        | Term 
 
        | In lymphocytes, what is the nucleus volume/cytoplasm ratio? How does the cytoplasm stain? |  | Definition 
 
        | High ratio of nuc volume to cyto volume Stains blue or purple slightly
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        | Term 
 | Definition 
 
        | 4-8% WBCs Largest leukocytes
 Nucleus is kidney shaped
 Transform into macrophages, leave blood stream and enter loose (areolar) connective tissue
 -phargocytic cells
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        |  | 
        
        | Term 
 | Definition 
 
        | cells fragements- break off from megakaryocytes in bone marrow -have vesicles containing molecules that help initiate the clotting of blood
 -form platelet plug to prevent loss of blood from injured blood vessel
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