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Chapter 8 medical term
Cardiovascular system
94
Anatomy
Graduate
09/27/2009

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Term
Autonomic nervous system
Definition
Portion of the nervous system that regulates involuntary actions, such as heart rate, digestion, and peristalsis
Term
Leaflet
Definition
Thin, flattened structure; term used to describe the leaf-shaped structures that compose a heart valve
Term
Lumen
Definition
Tubular space or channel within any organ or structure of the body; space within an artery, vein, intestine, or tube
Term
Regurgitation
Definition
Backflow or ejecting of contents through an opening
Term
Sphincter
Definition
Circular muscle found in a tubular structure or hollow organ that cocnstricts or dilates to regulate passage of substances through its opening
Term
Vasoconstriction
Definition
Narrowing of the lumen of a blood vessel that limiits blood flow, usually as a result of diseases, medications, or physiological processes.
Term
Vasodilation
Definition
Widening of the lumen of a blood vessel caused by the relaxing of the muscles of the vascular walls
Term
viscosity
Definition
state of being sticky or gummy (a solution that has high viscosity is relatively thick and flows slowly)
Term
aneurysm/o
Definition

widened blood vessel

anerysmorrhaphy: suture of an aneurysm

Term

angi/o

vascu/o

aort/o

Definition

vessel (usually blood or lymph)

i.e. angioplasty (angioplasty includes any endovascular procedure that reopens narrowed blood vessels and restores blood flow

Vasculitis: inflammation of blood vessels

aortostenosis: narrowing of the aorta

Term
arteriol/o
Definition
arteriole
Term
atri/o
Definition

atrium

i.e. atriomegaly

Term
arther/o
Definition

fatty plaque

atheroma: tumor of fatty plaque (artheromas are formed when fatty plaque builds up on the inner lining of arterial walls.  As calcium and other minerals are absorbed by plaque, the vessel hardens.

Term
cardi/o
Definition
heart
Term
embol/o
Definition

embolus (plug)

i.e. embolectomy: removal of an embolus (an embolectomy is the removal of a clot or other foreign material from a blood vessel.  Most emboli are blood clots - thrombi- htat have been transported from a distant vessel by the blood.

Term
hemangi/o
Definition

blood vessel

i.e hemangioma: tumor of blood vessels.  infantile hemangiomas are also called birthmarks.  They are not considered malignant and usually disappear over time.

Term
my/o
Definition
muscle
Term

phleb/o

ven/o

Definition

vein

i.e.

phlebectasis: expansion of a vein

Term
scler/o
Definition

hardening; sclera (white of eye)

aiel arteriosclerosis - the most common cause of arteriosclerosis is the presence of an arteroma in te vessel.  other common causes include smoking, diabetes, hig blood pressure, obesity, and family tendency.

Term
sept/o
Definition

septum

i.e. septostomy: a temporary procedure performed to increase systemic oxygenation in infants with congenital heart defects until corrective surgery can be performed.

Term
sphygm/o
Definition

pulse

i.e. sphygmoid: resembling a pulse

Term
sten/o
Definition

narrowing, stricture

ie. stenotic: pertaing to a narrowing or a stricture

Term
thromb/o
Definition

blood clot

i.e. thrombolysis: in thrombolysis, ezymens that destroy blood clots are infused into the occluded vessel.

Term
ventricul/o
Definition
ventricle ( of the heart or brain)
Term
-sphyxia
Definition

pulse

ie: asphyxia - without a pulse; also called suffocation.  Te term asphyxia usually refers to death caused by anoxia

Term
extra-
Definition

outside

ie; extravascular

Term
trans-
Definition

across

i.e. transeptal: across the septum

Term
aneurysm
Definition
Localized abnormal dilation of a vessel, usually an artery
Term

Arrest

cardiac

circulatory

Definition

Condition of being stopped or bringing to a stop

 

loss of effective cardiac function, which results in cessation of circulation.  Cardiac arrest may be due to ventricular fibrillation or asystole in which there there is no observable myocardial activity.

 

Cessation o fthe circulation of blood due to ventricular standsill or fibrillation

Term
Arrythymia
Definition
Inability of the heart to maintain a normal sinus rhytm, possibly including a rapid or slow beat or "skipping" a beat; also called dysrhythmia
Term
bruit
Definition
soft blowing sound heard on auscultation, possibly due to vibrations associated with the movement of blood, valvular action, or both; also called murmur
Term
cardiomyopathy
Definition
Any disease or weakening of heart muscle that diminishes cardiac function.  causes of cardiomyopathy include viral or bacterial infections, metabolic disorders, or general systemic disease
Term
catheter
Definition
thin flexible hollow plastic tube that is small enough to be threaded through a vein, artery, or tubular structure
Term
coarctation
Definition
narrowing of a vessel, esp. the aorta
Term
deep vein thrombosis (DVT)
Definition

blood clot that forms in the deep veins of the body, esp. those in the legs or thights.

In DVT, blood clots may break away from the vien wall and travel in the body.  If they lodge in the lung, the condition is called pulmonary embolism.  Pulmonary embolism may be life threatening if a large portion of the lung is damaged.

Term
Ejection Fraction (EF)
Definition
Calculation of how much blood a ventricle can eject with one contraction.  The left ventricular EF averages 50-75% in healthy hearts but can be markedly reduced if part of the heart muscle dies, as evident after na MI or in cardiomyopathy or valvular heart disease.
Term
Heart Failure
Definition
Failure of the heart to supply an adequate amount of blood to tissues and organs.  HF is commonly caused by impaired coronary blood flow, cardiomyopathies, and heart valve disease.
Term
embolus
Definition
mass of undissolved matter (foreign object, air, gas, tissue, thrombus) circulating in blood or lymphatic channels until it becomes lodged in a vessel.
Term
Fibrillation
Definition
Quivering or spontaneous muscle contractions, especially of the heart, causing ineffectual contrations.  Fibrillation is commonly corrected with a defibrillator
Term
Hemostasis
Definition
arrest of bleeding or circulation
Term
hyperlipidemia
Definition
excessive amounts of lipids (cholesterol, phospholipids, and triglycerides in the blood.  teh term hypercholesterolemia refers to elevation of cholesterol in the blood. It has been associated with an increased risk of atherosclerosis.
Term
Hypertension (HTN)
Definition

common disorder characterized by elevated bp persistently exceeding 149mm Hg systolic or 90mm Hg diastolic

Primary HTN in which there is no identifiable cause; also called essential hypertension: iit is the most common form of HTN and is associated with obesity, a high serum sodium level, hypercholesterolemia, or family history.

Secondary HTN results from an underlying identifible commonly correctable cause.

Term
Hypertensive heart disease
Definition
Any heart disorder cuased by prolonged hypertension including left ventricular hypertrophy, coronary artery disease,cardiac arrhythmias, and HF
Term
Implantable cardioverterdefibrillator (ICD)
Definition
implantable battery-powered device that monitors and automatically corrects ventricular tachycardia or fibrillation by sending electrical impulses to the heart.  In ventricular fibrillation, the heart quivers rather than beats, and blood is not pumped to the brain.  Unless tx is received within 5-10 minutes, ventricular fibrillation causes death.
Term
Infarct
Definition
Area of tissue that undergoes necrosis following cessation of blood supply.
Term
Ischemia
Definition
Local and temporary deficiency of blood supply due to circulatory obstruction
Term
Mitral valve prolapse (MVP)
Definition
common and occasionally serious condition in which the leaflets of the heart and occasionally, panic attacks with pounding heartbeat.  Because of the possibility of valve infection, prophylactic treatement with antibiotics is suggested before undergoing invasive procedrues such as dental work.
Term
radioisotope
Definition
chemical radioactive material used as a tracer to follow a substance through the body or a structure
Term
palpitation
Definition
sensation that the heart is not beating normally, possibly including thumping, fluttering, skipped beats, or a pounding feeling in the chest.  Alhtough most palpitations are harmless, those caused by arrhythmias may be serious.  Medical attention should be sought if palpitations are accompanied by pain, dizziness, overall weakness, or SOOB
Term
Patent ductus arteriousus
Definition
Failure of the ductus arteriosis to close after birth, allowingblood to flow from the aorta into the pulmonary artery
Term
Perfusion
Definition
circulation of blood through tissues or the passage of fluids through vessels of an organ
Term
Tetralogy of Fallot
Definition
Congenital anomaly consisting of four elements: 1 pulmonary artery stenosis, 2, interventricular septal defect, 3 transposition of the aorta so that both ventricles empty into the aorta, aand 4 right ventricular hypertrophy caused by increased workload of the right ventricle.
Term
stent
Definition
slender or threadlike device used to hold open vessels, tubes, or obstructed arteries. stents are used to support tubular structures that are being anastomosed or to induce or maintain patency within these tubular structures.
Term
Thrombus
Definition
Blood clot that obstructs a vessel
Term
caridac catheterization
Definition
passage of a catheter into the heart through a vein or artery to provide a comprehensive evaluation of the heart.  CC gathers information about the heart, such as blood supply through the coronary arteries and blood flow and pressure in the chambers of the ehart as well as enabling blood sample collection and xrays of the heart
Term
electrocardiogram (EKG, ECG)
Definition
graphic line recordeing that shows the spread of electrical excitation to different parts of the heart using small metal electrodes applied to the chest, arms, and legs
Term
Hoter monitor test
Definition
ECG taken with a small portable recording system capable of storing up to 24 hours of ECG tracings.  useful in obtaining a cardia arrhythmia record that would be missed during an ECG of only a few minutes duration
Term
Stress test
Definition
ECG taken under controlled exersie stress conditions. A stress test may show abnormal ECG tracings that do not appear during an ECG taken when the patient is resting.
Term
Nuclear
Definition
ECG that utilizes a radioisotope to evaluate coronary blood flow. In a nuclear stress test, the radioisotope is injected at the height of exercise. The area not recieving sufficient oxygen is visualized by decrease uptake of the isotope.
Term
Cardiac enzyme studies
Definition
Blood test that measures troponin T, troponin I, and creatinine kinase. Their presence in a blood specimen is consistent with myocardial damage.
Term
Lipid panel
Definition
series of tests (total cholesterol, high density lipoprotein, low density lipoprotein, and triglycerides) used to assess risk factors of ischemic heart disease.
Term

Angiography

 

Definition

Radiographic imaging of the heart and blood vessels after injection of a contrast dyd.

 

coronary: angiography to determine the degree of obstruction of the arteries that supply blood to the heart. in coronary angiography, a cateter is inserted into the femoral artery and threaded to the aorta. the contrast dye outlines the coronary arteries and show narrowin, stenosis, or blockage.

Digital subtraction: angiography in which two radiographic images are obtained, the first one without contrast material and the second one after a contrast material has been injected, and then compared by a computer that digitally subtracts the images of soft tissues, bones, and muscles, leaving only the images of vessels with contrast.

Term
Aortography
Definition
radiological examination of the aorta and its branches following injection of a contrast medium via a catheter
Term
echocardiography (ECHO)
Definition

noninvasive diagnostic method that uses ultrasound to visualize internal cardiac structures and produce images of the heart.  A transducer is placed on the chest to direct ultra-high frequency sound waves toward cardiac structures. Refelcted echoes are then converted to electrical impulses and displayed on a screen.

 

Doppler ultrasound: noninvasive adaptation of ultrasound technology in which blood flow velocity is assessed in different areas of the heart. Sound waves strike moving red blood cells and are reflected back to a recording device that graphically records blood flow through cardiac structures.

Term
Magnetic resonance imaging (MRI)
Definition
noninvasive technique that uses radiowaves and a strong magnetic field rather than an x-ray beam to produce multiplanar cross-sectional images of blood vesels.  MRI provide info about aneurysms, cardiac structures, and cardiac output.  Magnetic resonance angiography (MRA) is a type of MRI that provides hightly detailed images of the blood vessels. MRA is used to view arteries and blockages within the arteries.  A radiopaque contrast dye can be injected to provide greated detail of body structures.
Term
Multiple-gated acquisition (MUGA)
Definition
Nuclear procedrue that uses radioactive tracers to produce movie-like images of the structures of the heart, including the myocardium and the mitral and tricuspid valves.  The MUGA scan show the motion of the heart wall muscle and the ventricle's ability to eject blood (ejection fraction).
Term
Phonocardiography
Definition
Imaging technique that provides a graphic display of heart sounds and murmurs during the cardiac cycle.  In phonocardiogrphy, a transducer sends ultrasonic pulses through the chest wall and the echoes and converted into images on a monitor to assess overall cardiac performance.
Term
Scintigraphy
Definition

Diagnostic test that uses radiation emitted by the body after an injection of radioactive substances to create images of various organs or identify body functions and diseases.  Scintigraphy identifies infarcted or scarred areas of the heart that show up as cold spots (areas of reduced radioactivity), taken when the patient is at rest.

 

Thallum Study-scinitgraphy procedure that uses injected radioactive thallium and records the uptake of the iostope with a gamma camera to produce an image.

A stress thallium study is commonly performed at the same tiem as a resting study, and the two images are compared to further identify abnormalities.

Term
Sclerotherapy
Definition
Injection of a chemical irritant (sclerosing agent) into a vein to produce inflammation and fibrosis that destroys the lumen of the vein.  Sclerotherapy is commonly performed to treat varicose veins and sometimes telangiectasis
Term
Venography
Definition
Radiography of a vein after injection of a contrast medium to detect incomplete filling of a vewin, which indicates obstruction.  Venography is used primarily to locate blood clots in veing of the leg.
Term
Cardioversion
Definition
Procedure to restore normal rhythm of the heart by applying a controlled electrical shock to the exterior of the chest.
Term
Embolization
Definition
Technique used to block blood flow to a site by passing a catheter to the area and injecting a synthetic material or medication specially designed to occlude the blood vessel. 
Term

Angioplasty

 

Coronary artery bypass graft

 

Percutaneous transluminal coronary angioplasty (PTCA)

Definition

Procedure that alters a vessel through surgery or dilation of the vessel using a balloon catheter.

 

Coronary artery bypass graft: Surgical proceddure that uses a vessel graft from another part of the body to bypass the blocked art of a coronary artery and restore blood supply to the heart muscle.

 

PTCA: Dilation of an occluded vessel using a ballon catether under fluoroscopic guidance.  IN PTCA, the physician inserts a catheter transcutaneously, inflates the balloon thereby dilating the narrowed vessel, and commonly positions a stent to hold the vessel open

 

Term
Artherectormy
Definition
Removal of material from an occluded vessel using a specially designed catheter fitted with a cutting or grinding device.
Term
Biopsy
Definition

Removal and examination of a small piece of tissue for diagnostic purposes

 

Arterial biopsy: Removal and examination of a segment of an arterial vessel wall to confirm inflammation of the wall or arteritis, a type of vasculitis.

Term
catheter ablation
Definition
Destruction of conduction tissue of the heart to interrupt the abnormal conduction pathway causing the arrhythmia, thus allowing normal heart rhythm to resume.  Catheter ablation is usually performed under fluoroscopic guidance.
Term
Commissurotomy
Definition

Surgical separation of the leaflets of the mitral valve, which have fused together at their "commissures" (points of touching)

Many candidates for commissurotomy are now treated with balloon mitral valvuloplasty

Term
Laser ablation
Definition
Procedure used to remove or treat varicose veins.  In laser ablation, the laser's heat coagulates blood inside the vessel, causing it to collapse and seal.  Later, the vessels dissolve within the body, becoming less visible, or dissapear altogether
Term
Ligation and stripping
Definition

Tying a varicose vein (ligation) followed by removal (stipping) of the affected segment.

Ligation and stripping are procedruees performed for heavily damaged or diseased veins.  Usual treatment for varicose veins is laser ablation in combination with microplebectomies and sclerotherapy

Term
open heart surgery
Definition
Surgical procedrue performed on or within the exposed heart, usually iwth the assistance of a heart lung machine.  During the operation, the heart-lung machine takes over circulation to allow surgery on the resting (Nonbeating) heart.  After the heart has been restarted and is beating, the patient is disconnected from the heart-lung machine.  Types of open heart surgery include coronary artery bypass graft, valve replacement, and heart transplant.
Term
Pericardiocentesis
Definition
Puncturing of the pericardium to remove excess fluid from the pericardial sac or to test for protein, sugar, and enzymes or determine the causitive organism of pericarditis.
Term

Thrombolysis

 

Intravascular

Definition

Destruction of a blood clot using aticlotting agents called clot-busters, such as tissue plaminogen activator.  Prompt thrombolysis can restore blood flow to tissue before serious irreversible damage occurs.  However, many thrombolytic agents also pose the risk of hemorrhage.

 

Infusion of a thrombolytic agent into a vessel to dissolve a blood clot

Term
Valvotomy
Definition
Incision of a valve to increase the size of the opening; used in treating mitral stenosis.
Term
Venipuncture
Definition
Puncture of a vein by a needle attached to a syringe or catheter to withdraw a specimen of blood; also called phlebotomy
Term
Angiotensin-converting enzyme inhibitors
Definition
Lower blood pressure by inhibiting the conversion of angiotensin 1 (an inactive enzyme) to angiotensin II (a potent vasoconstrictor)  Angiotensin-converting enzyme (ACE) inhibitors are also used to treat hypertension alone or with other agents and aid in the management of heart failure.  I.E. Benazepril - Lotensin, Captopril - Capoten
Term
Antiarrhythmics
Definition
Prevent, alleviate, or correct cardiac arrhythmias (dysrhythmias) by stabilizing the electrical conduction of the heart.  Antiarrhythmics are used to treat atrial and ventricular dysrhythmias.  I.e. Flecainide -Tambacor
Term
Beta-blockers
Definition
Block the effect of adrenaline on beta receptors, which slow nerve pulses that pass through the heart, thereby causing a decrease heart rate and contractility. i.e. atenolol - tenormin, Metoprolol - Lopressor, Toprol-XL
Term
Calcium Channel Blockers
Definition
Block movement of calcium (required for blood vessel contraction) into myocardial cells and arterial walls, causing heart rate and blood pressure to decrease.  Calcium channel blockers are used to treat angina pectoris, hypertension, arrhythmias, and heart failure. I.E. amlodipine - Norvasc, Diltiazem-Cardizem CD, Nifedipine - Adalat CC, Procardia
Term
Diuretics
Definition
Act on kidneys to increase excretion of water and sodium.  Diuretics reduce fluid build-up in the body, including fluid in the lungs, a common symptom of heart failure.  Diuretics are also used to treat hypertension. I.e. Furoseminde - Lasix
Term
Nitrates
Definition
Dialate blood vessels of the heart, causing an increase in the amount of oxygen delivered to the myocardium, and decrease venous return and arterial resistance, which decreases myocardial oxygen demand and relieves angina.  Nitrates can be administered in several ways: sublingually as a spray or tablet, orally as a tablet, transdermally as a patch, topically as an ointment, or intravenously in an emergency setting.  I.e. Nitroglycerin, Nitrolingual, Nitrogard, Nitrostat
Term
Statins
Definition
Lower cholesterol in the blood and reduce its production in the liver by blocking the enzyme that produces it.  Vitorin, a statin drug, combined with a cholesterol absorption inhibitor not only lowers cholestero in the blood and reduces its production in the liver, but also decreases absorption of dietary cholesterol from the intestine.  Hypercholesterolemia is a major factor in the development of heart disease.  Dilate arteres in skeletal muscles, thus improving peripheral blood flow.  i.e. Atorvastatin - Lipitor; Simvastatin - Zocor; Simvastatin and ezetimibe - Vytorin
Term
Peripheral Vasodilators
Definition
Peripheral vasodilators treat periperal vascular diseases, diabetic peripheral vascular insufficiecy, and Taynaud disease. I.e. Cyclandelate - cyclan; Isoxsuprine - Vasodilan
Term
Abreviations
Definition

AAA - Abdominal aortic aneurysm

ACE: Angitensin - converting enzyme (inhibitor)

AF: Atrial Fibrillation

AS: Aortic Stenosis

ASD: Atrial Septal Defect

ASHD: Arteriosclerotic heart disease

AST: Angiontensin Sensitivity test

AV: Atrioventricular; arteriovenous

BBB: Bundle-branch block

BP, B/P: Blood Pressure

CA: Cancer; chronological age, cardiac arrest

CABG: Coronary artery bypass graft

CAD: Coronary artery disease

CC: Cardiac catheterization

CCU: Coronary care unit

CHD: Coronary Heart disease

Chol: Cholesterol

CK: creatine kinase (cardiac enzyme); conductive keratoplasty

CPR: Cardiopulmonary resuscitation

CV: Cardiovascular

DES: Drug-eluting stent

DOE: dyspnea on exertion

DSA: Digital subtraction angiography

DVT: Deep vein thrombosis, deep venous thrombosis

ECG, EKG: electrocardiogram; electrocardiography

ECHO: echocardiogram echocardiography; echoencephalogram, echoencephalography

EF: ejection fraction

ETT: Exercise tolerance test

HDL: High density liproproteins

HF: Heart Failure

HTN: Hypertension

ICD: Implantable cardioverter defibrillator

IV: Intravenous

LA: Left atrium

LD: Lactate dehydrogenase; lactic acid deydrogenase (cardiac enzyme)

LDL: low-density lipoprotein

LV: left ventricle

MI: myocardial infarction

MR: mitral regurgitation

MRA: Magnetic resonance angiogram; magnetic resonance angiography

MRI: magnetic resonance imaging

MS: musculoskeletal; multiple sclerosis; mitral stenosis; mental status

MUGA: Multiple-gated acquisition (scan)

MVP: Mitral valve prolapse

NSR: normal sinus rhythm

PAC: premature atrial contraction

PTCA: percutaneous transluminal coronary angioplasty

PV: premature ventricular contraction

RA: right atrium

RV: residual volume; right ventricle

SA, S-A: Sinoatrial

SOB: Shortness of breath

VSD: ventricular septal defect

VT: Ventricular tachycardia.

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