| Term 
 
        | Name three types of cartilage |  | Definition 
 
        | - hyaline - elastic
 - fibrocartilage
 |  | 
        |  | 
        
        | Term 
 
        | Name two types cartilage growth |  | Definition 
 
        | - appositional growth - interstitial growth
 |  | 
        |  | 
        
        | Term 
 
        | What is appositional growth? |  | Definition 
 
        | Cartilage growth from perichondirum |  | 
        |  | 
        
        | Term 
 
        | What is interstitial growth? |  | Definition 
 
        | Cartilage growth by chondrocytes |  | 
        |  | 
        
        | Term 
 
        | Name the functions of the Skeletal System |  | Definition 
 
        | 1. support 2. protection
 3. movement
 4. mineral storage
 5. hematopoiesis (blood cell formation)
 |  | 
        |  | 
        
        | Term 
 
        | Name the two layers of perichondrium and their contents |  | Definition 
 
        | 1. fibrous layer - collagen fibers
 - fibroblast
 2. cellular layer
 - chondroblast (chondrogenic cells)
 |  | 
        |  | 
        
        | Term 
 
        | Name the characteristics of specialized cartilage tissue |  | Definition 
 
        | - chondrocytes in lacunae - solid ground substance & fibers
 - avascular
 - no nerves
 - perichondrium
 - water-resilient
 |  | 
        |  | 
        
        | Term 
 
        | Describe long bones and give examples |  | Definition 
 
        | Description: bones longer than they are wide Examples: humerus, phalanges, extremities
 |  | 
        |  | 
        
        | Term 
 
        | Describe short bones and give examples |  | Definition 
 
        | Description: cube shaped Examples: patella, carpal/tarsal bones
 |  | 
        |  | 
        
        | Term 
 
        | Describe flat bones and give examples |  | Definition 
 
        | Description: two plates of compact bone encasing a thin layer of spongy bone (diploe) Example: cranial bones, scapula, sternum, ribs
 |  | 
        |  | 
        
        | Term 
 
        | Describe irregular bones and give examples |  | Definition 
 
        | Description: shapes that doesn't fit in the other categories Example: vertebrae, coxal bones
 |  | 
        |  | 
        
        | Term 
 
        | What does spongy (aka cancellous) bone consist of? |  | Definition 
 
        | - trabeculae - red bone marrow
 |  | 
        |  | 
        
        | Term 
 
        | In compact bone, what does an osteon consist of? |  | Definition 
 
        | - central canal - lamellae
 - osteocyte (in life located in the lacuna)
 - canaliculi
 - volkmann's canal
 |  | 
        |  | 
        
        | Term 
 
        | What is the chemical composition of bone? |  | Definition 
 
        | Organic: cells, collagen fibers, ground substance Inorganic: calcium phosphate, mineral salts
 |  | 
        |  | 
        
        | Term 
 
        | What is ossification (or osteogenisis)? |  | Definition 
 
        | Laying down new bone material by osteoblasts |  | 
        |  | 
        
        | Term 
 
        | In bone deposition, what's the function of osteoblasts? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | In bone reabsorption, what is the function of osteoclasts? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is intramembranous ossification? |  | Definition 
 
        | Development of flat bones from messenchyme (messenchyme cells become osteoblasts > osteoblasts form bone)
 |  | 
        |  | 
        
        | Term 
 
        | What is endochondral ossification? |  | Definition 
 
        | Hyaline cartilage (in epiphyseal plate) is replaced by bone |  | 
        |  | 
        
        | Term 
 
        | Describe the anatomy of the epiphyseal growth area |  | Definition 
 
        | From top to bottom: 1. resting zone
 2. proliferation zone
 3. hypertrophic zone
 4. calsification zone
 5. ossification zone
 |  | 
        |  | 
        
        | Term 
 
        | What happens in the proliferation zone of the epiphyseal plate? |  | Definition 
 
        | Cartilage cells undergo mitosis |  | 
        |  | 
        
        | Term 
 
        | What happens in the hypertrophic zone of the epiphyseal plate? |  | Definition 
 
        | Older cartilage cells enlarge |  | 
        |  | 
        
        | Term 
 
        | What happens in the calcification zones of the epiphyseal plate? |  | Definition 
 
        | Matrix becomes calcified (hardened); cartilage cells die; matrix begins deteriorating |  | 
        |  | 
        
        | Term 
 
        | What happens in the ossification zone of the epiphyseal plate? |  | Definition 
 
        | New bone formation is occurring |  | 
        |  | 
        
        | Term 
 
        | Postnatal growth of Endochondral "long" bones |  | Definition 
 
        | childhood and adolescence, the endochondral bone lengthen by growth of epiphyseal plate, but that plate begins to diminish and thus stops lengthening of the bone during adulthood |  | 
        |  | 
        
        | Term 
 
        | How does the growth hormone effect bones growth? |  | Definition 
 
        | the somatrophic hormone stimulates the growth of the epiphyseal plate |  | 
        |  | 
        
        | Term 
 
        | How does the thyroid hormone effect bone growth? |  | Definition 
 
        | It modulates the growth hormone and leads to a proportional skeleton |  | 
        |  | 
        
        | Term 
 
        | How does the sex hormone effect bone growth? |  | Definition 
 
        | It leads to the  early closure of epiphyseal plate and stops growth |  | 
        |  | 
        
        | Term 
 
        | What are the 4 stages of healing a fracture? |  | Definition 
 
        | 1. hematoma formation 2. fibocartilaginous callus formation
 3. bony callus formation
 4. bone remodeling
 |  | 
        |  | 
        
        | Term 
 
        | When healing a fracture, what happens in hematoma formation? |  | Definition 
 
        | blood is released and clots to form a hematoma |  | 
        |  | 
        
        | Term 
 
        | When healing a fracture, what happens in fibrocartiaginous callus formation? |  | Definition 
 
        | new blood vessels grow in clot and repair tissue called soft callus invade the clot to form DCT |  | 
        |  | 
        
        | Term 
 
        | When healing a fracture, what happens in bony callus formation? |  | Definition 
 
        | by endochondral ossification, trabeculae of new bone begin to form in the callus |  | 
        |  | 
        
        | Term 
 
        | When healing a fracture, what happens in bone remodeling? |  | Definition 
 
        | bony callus is remodeled and new bone is made like the original unbroken bone |  | 
        |  | 
        
        | Term 
 
        | What are the six most common types of fractures? |  | Definition 
 
        | 1. comminuted 2. compression
 3. spiral
 4. epiphyseal
 5. depressed
 6. greenstick
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | low bone mass and deterioration of microscopic architecture of bony skeleton |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | bones are inadequately mineralized resulting in soft and weak bones |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | vitamin D deficiency that results in softening and distortion ex. bow legs
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | excessive rates of bone deposition and bone reabsoption, resulting in soft and weak bones |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | form of bone cancer, cancer cells deriving from osteoblast-like cells |  | 
        |  |