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Chapter 6: BONES
Bone structures, classifications, and disorders
26
Anatomy
Undergraduate 2
09/30/2013

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Term
osteocyte
Definition
mature bone cells that cannot divide
Term
osteoblast
Definition
mature bone cell that produces new bony matrix
Term
osteoprogenitor cells
Definition
mesenchymal cells that produce cells that differentiate into osteoblast
Term
osteoclasts
Definition
remove and remodel bone matrix
Term
Functions of skeletal system:
Definition
1. support 2. storage of minerals 3.leverage 4. blood cell production 5. protection
Term
Classifications of bones (6):
Definition
1. long 2. short 3. sesamoid 4. flat 5. sutural 6. irregular
Term
206 total bones: How many in axial skeleton and appendicular skeleton?
Definition
axial= 80 bones
appendicular= 126 bones
Term
appositional bone growth..
Definition
increases bone diameter of existing bones
Term
2 layers of periosteum
Definition
-fibrous outer layer
-cellular inner layer
Term
periosteum functions (3):
Definition
1) isolate bone from surrounding tissue
2) route for blood and nervous supply
3) actively participate in bone growth and repair
Term
Perforating fibers...
Definition
strongly connect tendons, ligaments, and joint capsules to bone through periosteum
Term
endosteum
Definition
incomplete cellular layer lining the medullary cavity
Term
achondroplasia
Definition
limbs are short, trunk is normal size
Term
pituitary growth failure
Definition
reduction in growth hormone leads to short bones
Term
gigantism
Definition
overproduction of growth hormone before puberty
Term
marfan syndrome
Definition
causes long slender limbs, may also cause cardiovascular issues
Term
acromegaly
Definition
growth hormone levels rise causing thicker bones (esp in face) after puberty
Term
fibrodysplasia ossificans progressive (FOP)
Definition
gene mutation that causes bones deposition around skeletal muscles
Term
most abundant mineral in the body is...
Definition
calcium
~99% deposited in skeleton
Term
levels of calcium controlled by activities of:
Definition
intestines, bones, and kidneys
Term
As a calcium reserve, skeleton has primary role in ________
Definition
calcium homeostasis
Term
fracture
Definition
crack or break in bone due to extreme mechanical stress
Term
steps of fracture repair (4):
Definition
1) fracture hematoma develops (blood clot)
2) calluses form
3) calluses replaced and dead bone removed
4) remodeling of healed bone
Term
completely internal fractures (only seen on xrays) are known as ________
Definition
closed or simple
Term
fractures that project through the skin are known as _________
Definition
open or compound
Term
open or compound fractures are more dangerous because ______________
Definition
uncontrolled bleeding and infection
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