| Term 
 
        | Role of the alimentary canal |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Structures of the alimentary canal |  | Definition 
 
        | Mouth, pharynx, esophagus, stomach, small intestine, and large intestine |  | 
        |  | 
        
        | Term 
 
        | Accessory digestive organs |  | Definition 
 
        | teeth, tongue, gallbladder, salivary glands, liver, and pancreas |  | 
        |  | 
        
        | Term 
 
        | Role of accessory digestive organs |  | Definition 
 
        | produce secretions that help digest food |  | 
        |  | 
        
        | Term 
 
        | Six essential activities of the digestive process |  | Definition 
 
        | Ingestion, Mechanical digestion, Propulsion, Chemical digestion, Absorption, Defecation |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | taking food into the digestive tract |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | chewing, mixing, and churning food |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | swallowing and peristalsis |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | waves of contraction and relaxation of muscles in the organ walls |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | rhythmic constriction of the intestines that mixes food with digestive juices |  | 
        |  | 
        
        | Term 
 
        | Gastrointestinal activities |  | Definition 
 
        | Chemical digestion, absorption, defecation |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | catabolic breakdown of food |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | movement of nutrients from the GI tract to the blood or lymph |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | elimination of indigestible solid wastes |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | external environment for the digestive process |  | 
        |  | 
        
        | Term 
 
        | Regulation of digestion involves? |  | Definition 
 
        | Mechanical and chemical stimuli, extrinsic control, intrinsic controls |  | 
        |  | 
        
        | Term 
 
        | Regulation of digestion: Mechanical and chemical stimuli |  | Definition 
 
        | stretch receptors, osmolarity, presence of substrate in the lumen |  | 
        |  | 
        
        | Term 
 
        | Regulation of digestion: Extrinsic control |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Regulation of digestion: Intrinsic control |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Receptors of the GI tract: What do mechano- and chemoreceptors respond to? |  | Definition 
 
        | stretch, osmolarity, and pH. Presence of substrate, and end products of digestion |  | 
        |  | 
        
        | Term 
 
        | Mechano and chemoreceptors initiate what reflexes? |  | Definition 
 
        | activate or inhibit digestive glands. mix lumen contents and move them along |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | serous membrane of the abdominal cavity |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | covers external surface of most digestive organs |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | lubricates digestive organs. allows them to slide across one another |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | double layer of peritoneum |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Vascular and nerve supplies to the viscera. hold digestive organs in place and store fat |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | organs outside the peritoneum |  | 
        |  | 
        
        | Term 
 
        | Peritoneal organs (intraperitoneal) |  | Definition 
 
        | organs surrounded by peritoneum |  | 
        |  | 
        
        | Term 
 
        | Splanchnic Circulation: Hepatic artery serves what organ? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Splanchnic Circulation: Splenic artery serves what organ? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Splanchnic Circulation: Left gastric artery serves which organ? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Splanchnic Circulation: Inferior mesenteric artery serves which organ? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Splanchnic Circulation: Superior mesenteric artery serves what organ? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Hepatic portal circulation: Collection |  | Definition 
 
        | Takes nutrient-rich venous blood from the digestive viscera |  | 
        |  | 
        
        | Term 
 
        | Hepatic portal circulation: Delivery |  | Definition 
 
        | Blood is delivered to the liver for metabolic processing and storage |  | 
        |  | 
        
        | Term 
 
        | Histology of the Alimentary Canal |  | Definition 
 
        | From esophagus to the anal canal the walls of the GI tract have the same four tunics |  | 
        |  | 
        
        | Term 
 
        | What are the four tunics? |  | Definition 
 
        | Lumen outward: Mucosa, submucosa, muscularis externa, and serosa |  | 
        |  | 
        
        | Term 
 
        | Specificity of the tunics? |  | Definition 
 
        | Each tunic has a predominant tissue type, specific digestive function |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | Mucus, digestive enzymes, and hormones |  | 
        |  | 
        
        | Term 
 
        | Mucosa: Digestive functions |  | Definition 
 
        | Absoprtion of digestion and products into blood (small intestine) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | protects against infection |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | Lamina propia of the mucosa |  | Definition 
 
        | contains capillaries that nourish the epithelium and collects digested material |  | 
        |  | 
        
        | Term 
 
        | Muscularis mucosae of the mucosa |  | Definition 
 
        | smooth muscle layers that produce local movement of mucosa |  | 
        |  | 
        
        | Term 
 
        | Submucosa: anatomy basics |  | Definition 
 
        | connective tissue pouch that helps organs, especially the stomach expand.  sheath that "holds" inner layers intact |  | 
        |  | 
        
        | Term 
 
        | Muscularis externa: Basic anatomy |  | Definition 
 
        | Layer of smooth muscle cells that perform segmentation or peristalsis |  | 
        |  | 
        
        | Term 
 
        | Muscularis externa: "Blocker" |  | Definition 
 
        | Thickened areas, called sphincters, prevent backflow |  | 
        |  | 
        
        | Term 
 
        | Muscularis externa: Inner layer |  | Definition 
 
        | runs with the circumference of tube, pushes forward, circular muscle |  | 
        |  | 
        
        | Term 
 
        | Muscularis Externa: Outer layer |  | Definition 
 
        | Longitudinal muscle. Runs the length of the tube. Pushes forward |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | "Sausage Casing" Visceral peritoneum that holds everything together |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | bounded by the lips and cheeks externally, and teeth and gums internally |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | area that lies within the teeth and gums |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | median fold that joins the internal aspect of each lip to the gum |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | underlain by palatine bones and palatine processes of maxillae |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | assists the tongue in chewing |  | 
        |  | 
        
        | Term 
 
        | Anatomy of the hard palate |  | Definition 
 
        | Slightly corrugated on either side of the raphe (midline ridge) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | mobile fold formed mostly of skeletal muscle |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Closes off the nasopharynx during swallowing |  | 
        |  | 
        
        | Term 
 
        | Soft palate - projections |  | Definition 
 
        | Uvula projects downward from its free edge |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Lingual frenulum secures the tongue to the floor of the mouth |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Produce and secrete saliva |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Cleanses the mouth, moistens and dissolves food chemicals, aids in bolus formation, contains enzymes that break down starch |  | 
        |  | 
        
        | Term 
 
        | Three pairs of extrinsic salivary glands |  | Definition 
 
        | Parotid, submandibular, sublingual |  | 
        |  | 
        
        | Term 
 
        | Parotid gland: Opens into... |  | Definition 
 
        | The vestibule next to second upper molar |  | 
        |  | 
        
        | Term 
 
        | Submandibular gland opens into... |  | Definition 
 
        | the base of the lingual frenulum |  | 
        |  | 
        
        | Term 
 
        | Sublingual gland opens... |  | Definition 
 
        | via 10-12 ducts into the floor of the mouth |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | secreted from serous and mucous cells of salivary glands |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Containing a lower concentration of osmotically active components than a standard solution. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 97-99.5% water, hypo-osmotic, slightly acidic solution |  | 
        |  | 
        
        | Term 
 
        | What does saliva contain? |  | Definition 
 
        | Electrolytes, digestive enzyme, proteins, metabolic wastes |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Na+, K+, Cl-, PO4 2-, HCO3- |  | 
        |  | 
        
        | Term 
 
        | Digestive enzyme of saliva |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | mucin, lysozyme, defensins, and IgA |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | Immunogoblin A, Antibody A |  | 
        |  | 
        
        | Term 
 
        | Metabolic wastes of saliva |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What do salivary glands secrete serous, enzyme-rich saliva in response to? |  | Definition 
 
        | Ingested food wich stimulates chemoreceptors and pressoreceptors, and the thought of food |  | 
        |  | 
        
        | Term 
 
        | What system inhibits salivation and results in dry mouth? |  | Definition 
 
        | Strong sympathetic stimulation |  | 
        |  | 
        
        | Term 
 
        | The mouth, the oro- and laryngopharanx allow passage of what? |  | Definition 
 
        | Food and fluids to the esophagus. air to the trachea |  | 
        |  | 
        
        | Term 
 
        | What is the pharynx lined with? |  | Definition 
 
        | Stratified squamous epithelium and mucus glands |  | 
        |  | 
        
        | Term 
 
        | What are the two skeletal muscle layers of the Pharynx? |  | Definition 
 
        | Inner longitudinal, Outer pharyngeal constrictors |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Muscular tube going from the laryngopharynx to the stomach |  | 
        |  | 
        
        | Term 
 
        | What does the esophagus travel through? |  | Definition 
 
        | The mediastinum and pierces the diaphragm |  | 
        |  | 
        
        | Term 
 
        | Where do the esophagus join the stomach? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | nonkeratinized stratified squamous epithelium |  | 
        |  | 
        
        | Term 
 
        | What is the shape of the esophagus when it is empty? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the shape of the esophagus when food is present? |  | Definition 
 
        | Flattened from resting position |  | 
        |  | 
        
        | Term 
 
        | What are the changes in the muscularis as the bolus moves from superior to inferior portions? |  | Definition 
 
        | Skeletal and smooth muscle respectively |  | 
        |  | 
        
        | Term 
 
        | Digestive Processes in the Mouth: Step 1 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Digestive Processes in the Mouth: Step 2 |  | Definition 
 
        | Mechanical digestion begins, mastication |  | 
        |  | 
        
        | Term 
 
        | Digestive Processes in the Mouth: Step 3 |  | Definition 
 
        | Propulsion is initiated by swallowing |  | 
        |  | 
        
        | Term 
 
        | Digestive Processes in the Mouth: Step 4 |  | Definition 
 
        | Salivary amylase begins breakdown of starch and simple sugars |  | 
        |  | 
        
        | Term 
 
        | Digestive Processes in the Mouth: Step 5 |  | Definition 
 
        | Pharynx and esophagus serve as conduits to pass food from the mouth to the stomach |  | 
        |  | 
        
        | Term 
 
        | Digestive Processes in the Mouth: Step 5 |  | Definition 
 
        | Oral cavity shapes the broken down mass into a bolus that is swallowed |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is swallowing (deglutition)? |  | Definition 
 
        | Coordinated activity of the tongue, soft palate, pharynx, esophagus, and 22 separate muscle groups |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | Tip of tongue must press against roof of mouth |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Bolus is forced into the oropharynx |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Once bolus is past the uvula swalling is out of our control |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Uvula and soft palette ascend and close off nasopharynx |  | 
        |  | 
        
        | Term 
 
        | Pharyngeal-esophygeal phase |  | Definition 
 
        | controlled by the medulla and lower pons |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Epiglottis descends blocking off trachea |  | 
        |  | 
        
        | Term 
 
        | Pharyngeal-esophygeal phase: Step 1 |  | Definition 
 
        | All routes except into the digestive tract are sealed off |  | 
        |  | 
        
        | Term 
 
        | Pharyngeal-esophygeal phase: Step 2 |  | Definition 
 
        | Peristalis moves food through the pharynx to the esophagus |  | 
        |  | 
        
        | Term 
 
        | Pharyngeal-esophygeal phase: Solids |  | Definition 
 
        | Food travels to the stomach in 8-10 seconds |  | 
        |  | 
        
        | Term 
 
        | Pharyngeal-esophygeal phase: Liquids |  | Definition 
 
        | Water, saliva, liquds reach stomach in 1-2 seconds |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Gastroesophageal reflux disease: Characterized by gastroesophageal sphincter not working properly |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Upper esophageal sphincter |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Gastroesophageal Sphincter |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | What chemical breakdown occurs in the stomach? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | 15 to 25 cm long. 50 ml volume. Can hold up to 4L when full. |  | 
        |  | 
        
        | Term 
 
        | What happens when the stomach is empty? |  | Definition 
 
        | Collapses into folds called rugae - the sound of stomach growling |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | surrounds the cardiac orifice |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Dome-shaped region beneath the diaphragm |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | midportion of the stomach |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | made up of the antrum and canal which terminates at the pylorus |  | 
        |  | 
        
        | Term 
 
        | What is the pylorus continuous with? |  | Definition 
 
        | The duodenum through the pyloric sphincter |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Pyloric Sphincter, active sphincter |  | 
        |  | 
        
        | Term 
 
        | Greater curvature of the stomach |  | Definition 
 
        | entire extent of the convex lateral surface |  | 
        |  | 
        
        | Term 
 
        | Lesser curvature of the stomach |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the stomach held in place by? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Two mesentearies of the stomach |  | Definition 
 
        | Lesser omentum, greature omentum |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Runs from the liver to the lesser curvature |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | drapes inferiorly from the greater curvature to the small intestine |  | 
        |  | 
        
        | Term 
 
        | Microscopic modifications of the anatomy of the stomach |  | Definition 
 
        | Muscularis - has an additional oblique layer |  | 
        |  | 
        
        | Term 
 
        | Role of the oblique layer of the muscularis |  | Definition 
 
        | Allows the stomach to churn, mix, and pummel food physically. Breaks down food into smaller fragments |  | 
        |  | 
        
        | Term 
 
        | What is the epithelial lining of the stomach composed of? |  | Definition 
 
        | Goblet cells that produce a coat of alkaline mucus |  | 
        |  | 
        
        | Term 
 
        | What is the role of the alkaline mucus produced by the goblet cells? |  | Definition 
 
        | Traps a bicarbonate-rich fluid beneath it |  | 
        |  | 
        
        | Term 
 
        | What do gastric pits contain? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What do gastric glands secrete? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What does gastric juice contain? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | hormone that stimulates secretion of gastric acid |  | 
        |  | 
        
        | Term 
 
        | Gastric glands of the fundus and body have what secretory cells? |  | Definition 
 
        | mucous neck cells, parietal cells |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | secrete HCL and intrinsic factor |  | 
        |  | 
        
        | Term 
 
        | What do Chief cells produce? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | How is pepsinogen activated by? |  | Definition 
 
        | HCl in the stomach. Pepsin itself via a positive feedback mechanism |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | enzyme that digests proteins into peptides |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | secrete digestive hormones into the lamina propia |  | 
        |  | 
        
        | Term 
 
        | What is the role of Cholecystokinin? |  | Definition 
 
        | A stimulating hormone which turns on enzymes that stimulate intestinal digestion of fats and proteins |  | 
        |  | 
        
        | Term 
 
        | What is the role of Somatostatin? |  | Definition 
 
        | Inhibitory hormone that suppresses gastrin release |  | 
        |  | 
        
        | Term 
 
        | What protective systems does the mucosal barrier contain? |  | Definition 
 
        | Thick coat of bicarbonate-rich mucus on the stomach wall. Epithelial cells that are joined by tight junctions. Gastric glands that have cells impermeable to HCl |  | 
        |  | 
        
        | Term 
 
        | Digestion in the stomach: Physical |  | Definition 
 
        | Holds ingested food. Degrades the food, deliver chyme to the small intestine, rolls and churns food |  | 
        |  | 
        
        | Term 
 
        | Digestion in the Stomach: Chemical |  | Definition 
 
        | Enzymatically digest proteins with pepsin, secretes intrinsic factor required for absorption of vitamin B12 |  | 
        |  | 
        
        | Term 
 
        | Three phases of digestion |  | Definition 
 
        | Cephalic control, gastric phase, intestinal phase |  | 
        |  | 
        
        | Term 
 
        | Cephalic Phase: Excitatory Events |  | Definition 
 
        | Triggers: sight smell, taste, thought of food Vagus nerve transmits signals to stomach glands
 |  | 
        |  | 
        
        | Term 
 
        | Cephalic Phase: Inhibitory Events |  | Definition 
 
        | Loss of appetite, Depressions, Decrease in in stimulation of the parasympathetic division |  | 
        |  | 
        
        | Term 
 
        | Gastric phase: Excitatory events |  | Definition 
 
        | Stomach distension, 3-4 hours long, 2/3 of gastric juices released during this time, activation of chemoreceptors by peptides caffeine, and rising pH, release of gastrin into blood |  | 
        |  | 
        
        | Term 
 
        | Gastric Phase: Inhibitory events |  | Definition 
 
        | a pH lower than 2, emotional upset that overrides the parasympathetic division |  | 
        |  | 
        
        | Term 
 
        | Intestinal Phase: Excitatory Phase |  | Definition 
 
        | low pH; partially digested food enters the duodenum and encourages gastric gland activity |  | 
        |  | 
        
        | Term 
 
        | Intestinal Phase: Inhibitory Phase |  | Definition 
 
        | distension of duodenum, presence of fatty, acidic, or hypertonic chyme, and /or irritants in the duodenum |  | 
        |  | 
        
        | Term 
 
        | Intestinal Phase: Inhibitory Action |  | Definition 
 
        | Initiates inhibition of local reflexes and vagal nuclei. Closes the pyloric sphincter. Releases enterogastrone that inhibits gastric secretion |  | 
        |  | 
        
        | Term 
 
        | Regulation and Mechanism of HCl secretion: What is HCl secretion stimulated by? |  | Definition 
 
        | Acetycholine, histamine, gastrin through second-messenger systems |  | 
        |  | 
        
        | Term 
 
        | When is release of HCl acid low? |  | Definition 
 
        | If only one ligand binds to parietal cells |  | 
        |  | 
        
        | Term 
 
        | When is release of HCl acid high? |  | Definition 
 
        | If all three ligands bind to parietal cells. |  | 
        |  | 
        
        | Term 
 
        | What role do antihistamines play in HCl release? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | How quick is muscle adaptation in stomach? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | At what point does stomach pressure cease to be constant? |  | Definition 
 
        | Until about 1L of food is ingested |  | 
        |  | 
        
        | Term 
 
        | How is the unchanging pressure of the stomach maintained? |  | Definition 
 
        | Reflex-mediated relaxation and plasticity |  | 
        |  | 
        
        | Term 
 
        | What are the reflex-mediate events? |  | Definition 
 
        | Receptive relaxation, adaptive releaxation |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | as food travels in the esophagus, stomach muscles relax |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | the stomach dilates in response to gastric filling |  | 
        |  | 
        
        | Term 
 
        | What is the basic electrical rhythm (BER) of gastric contractile activity initiated by? |  | Definition 
 
        | Pacemaker cells (Cells of Cajal) |  | 
        |  | 
        
        | Term 
 
        | Where does the most vigorous peristalsis and mixing occur? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What happens with chyme in the stomach? |  | Definition 
 
        | Delivered in small amounts to the duodenum. Forced backward into stomach for further mixing. |  | 
        |  | 
        
        | Term 
 
        | How is gastric emptying regulated? |  | Definition 
 
        | The neural enterogastric reflex. Hormonal (enterogastrone) mechanisms |  | 
        |  | 
        
        | Term 
 
        | What type of chyme moves faster through the duodenum? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | type of chyme is digested more slowly? What does this cause? |  | Definition 
 
        | Fat-laden. Food remains in the stomach longer |  | 
        |  | 
        
        | Term 
 
        | Small Intestine: Gross anatomy |  | Definition 
 
        | Runs from pyloric sphincter to the ileocecal valve. 20 ft long by 1-1.5" in diameter. |  | 
        |  | 
        
        | Term 
 
        | What are the three subdivisions of the small intestine? |  | Definition 
 
        | Duodenum, jejunum, and ileum |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | Duodenum: Physical role in digestion |  | Definition 
 
        | Site where food transfers from the stomach, along with bile and pancreatic juice |  | 
        |  | 
        
        | Term 
 
        | How is the Sphincter of Oddi regulated? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What part of the small intestine is the hepatopancratic ampulla? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the hepatopancratic ampulla? |  | Definition 
 
        | Site where the bile duct and main pancreatic duct enter the small intestine. Controlled by the hepatopancreatic sphincter |  | 
        |  | 
        
        | Term 
 
        | Other name for the hepatopancreactic sphincter |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What part of the small intestine joins the large intestine? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Where do the small intestine and large intestine meet? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | How are the jejunum and ileum organized? |  | Definition 
 
        | Hang like sausage links in the central and lower abdominal cavity |  | 
        |  | 
        
        | Term 
 
        | What are the jejunum and ileum suspended by? |  | Definition 
 
        | A thick fan-like mesentary |  | 
        |  | 
        
        | Term 
 
        | What do the structural modifications of the small intestine wall do? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the plicae circulares? |  | Definition 
 
        | Deep circular folds of the mucosa and submucosa |  | 
        |  | 
        
        | Term 
 
        | What are the villi of the small intestine? |  | Definition 
 
        | finger like extensions of the mucosa |  | 
        |  | 
        
        | Term 
 
        | What are the microvilli of the small intestine? |  | Definition 
 
        | Tiny projections of absorptive mucosal cells plasma membranes |  | 
        |  | 
        
        | Term 
 
        | What are the 4 modifications of the small intestine? Their role? |  | Definition 
 
        | Length, plicae circularis, Villi, Microvilli. To increase Surface area |  | 
        |  | 
        
        | Term 
 
        | What is the epithelium of the mucosa made up of? |  | Definition 
 
        | Absorptive cells and goblet cells. Enteroendocrine cells. Interspersed T-cells called intraepithelia lymphocytes |  | 
        |  | 
        
        | Term 
 
        | What is the role of intraepithelial lymphocytes (IELs)? |  | Definition 
 
        | Immediately release cytokines upon encountering a foreign protein (antogen) |  | 
        |  | 
        
        | Term 
 
        | What cells secrete intestinal juice? |  | Definition 
 
        | Cells of intestinal crypts (Crypts of Kieberkuhn) |  | 
        |  | 
        
        | Term 
 
        | What do the intestinal crypts (of Lieberkuhn) secrete intestinal juice in response to? |  | Definition 
 
        | Distension or irritation of the mucosa |  | 
        |  | 
        
        | Term 
 
        | What is intestinal juice made up of? |  | Definition 
 
        | Slighty alkaline, isotonic with blood plasma, largely water, enzyme poor, contains mucus |  | 
        |  | 
        
        | Term 
 
        | What is the largest gland in the body? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the four lobes of the liver? |  | Definition 
 
        | right, left, caudate, and quadrate |  | 
        |  | 
        
        | Term 
 
        | What separates the right and left lobes anteriorly? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What does the falciform ligament do? |  | Definition 
 
        | Suspends the liver from the diaphragm and anterior abdominal wall. |  | 
        |  | 
        
        | Term 
 
        | What is the ligamentum teres? |  | Definition 
 
        | A remnant of the fetal umbilical vein |  | 
        |  | 
        
        | Term 
 
        | What runs along the free edge of the falciform ligament? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What role does the lesser omentum play with the liver? |  | Definition 
 
        | Anchors it to the stomach |  | 
        |  | 
        
        | Term 
 
        | Where do the hepatic blood vessels enter the liver at? |  | Definition 
 
        | The porta hepatis - gateway to the liver |  | 
        |  | 
        
        | Term 
 
        | Where does the gallbladder rest? |  | Definition 
 
        | in a recess on the inferior surface of the right lobe |  | 
        |  | 
        
        | Term 
 
        | What two ducts form the bile duct? |  | Definition 
 
        | cystic duct and hepatic duct |  | 
        |  | 
        
        | Term 
 
        | What two ducts fuse to become the common hepatic duct? |  | Definition 
 
        | Right and Left Hepatic duct |  | 
        |  | 
        
        | Term 
 
        | How does bileve leave the liver? |  | Definition 
 
        | Via the hepatic duct and cystic duct |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | yellow-green, alkaline solution containing bile salts, bile pigments, cholesterol, neutral fats, phospholipids, and electrolyes |  | 
        |  | 
        
        | Term 
 
        | What are the bile slats derivatives of? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the roles of bile salts? |  | Definition 
 
        | Emulsify fat, facilitate fat and cholesterol absorption, help solubilize cholesterol |  | 
        |  | 
        
        | Term 
 
        | What happens with bile after being used? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the chief bile pigment |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is bilirubin a waste product of? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Gallbladder: Physical anatomy |  | Definition 
 
        | thin-walled green muscular (smooth muscle) sac on the ventral surface of the liver |  | 
        |  | 
        
        | Term 
 
        | What does the gallbladder store and concentrate? |  | Definition 
 
        | bile by absorbing its water and ions |  | 
        |  | 
        
        | Term 
 
        | How does the gallbladder release bile? |  | Definition 
 
        | Via the cystic duct, which flows into the bile duct |  | 
        |  | 
        
        | Term 
 
        | Regulation of Bile release: Step 1 |  | Definition 
 
        | Acidic, fatty chyme causes the duodenum to release CCK and secretin into the bloodstream |  | 
        |  | 
        
        | Term 
 
        | Regulation of Bile Release: Step 2 |  | Definition 
 
        | Bile salts and secretin transported in blood stimulate the liver to produce bile |  | 
        |  | 
        
        | Term 
 
        | Regulation of Bile Release: Step 3 |  | Definition 
 
        | CCK causes the gallbaldder to contract, the hepatopancreatic sphincter to relax |  | 
        |  | 
        
        | Term 
 
        | Regulation of Bile: Step 4 |  | Definition 
 
        | Result: bile enters the duodenum |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Lies deep to the greater curvature of the stomach. The head is encircled by the duodenum and the tail abuts the spleen |  | 
        |  | 
        
        | Term 
 
        | Pancreas: Exocrine Function |  | Definition 
 
        | Secretes pancreatic juice which breaks down all categories of foodstuff. Acini (clusters of secretory cells) contain zymogen granules with digestive enyzmes |  | 
        |  | 
        
        | Term 
 
        | Pancreas: Endocrine function |  | Definition 
 
        | release of insulin and glucagon |  | 
        |  | 
        
        | Term 
 
        | Composition of Pancreatic Juice |  | Definition 
 
        | Water soluition of enzymes and electrolytes (primarily bicarbonate HCO3-) |  | 
        |  | 
        
        | Term 
 
        | Function of pancreatic juice |  | Definition 
 
        | Neutralizes acidic chyme, provides optimal environment for pancreatic enzymes |  | 
        |  | 
        
        | Term 
 
        | What form are the enzymes when they are released from the pancreas? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Where do the inactive enzymes released from the pancreas become activated? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | How are the inactive enzymes of the pancreas activated in the duodenum? |  | Definition 
 
        | Via membrane-bound enteropeptidase |  | 
        |  | 
        
        | Term 
 
        | Wjat is trypsinogen activated to? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is chymo-tripsinogen activated into? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is procarboxypeptidase activated to? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the active enzymes secreted by the pancreas? |  | Definition 
 
        | Amylase (sugar) and lipases (fats) |  | 
        |  | 
        
        | Term 
 
        | What do amylase and lipases require for optimal activity? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Regulation of Pancreatic Secretion: Step 1 |  | Definition 
 
        | Secretin and CCK are released when fatty or acidic chyme enters the duodenum |  | 
        |  | 
        
        | Term 
 
        | Regulation of Pancreatic Secretion: Step 2 |  | Definition 
 
        | CCK and secretin enter the bloodstream |  | 
        |  | 
        
        | Term 
 
        | Regulation of Pancreatic Secretion: Step 3 |  | Definition 
 
        | CCK and secretin reach the pancreas via bloodstream |  | 
        |  | 
        
        | Term 
 
        | Regulation of Pancreatic Secretion: Step 3 |  | Definition 
 
        | CCK and secretin reach the pancreas via bloodstream |  | 
        |  | 
        
        | Term 
 
        | Regulation of Pancreatic Secretion: Step 4 |  | Definition 
 
        | CCK induces teh secretion of enzyme-rich pancreatic juice. Secretin causes secretion of bicarbonate-rich pancreatic juice |  | 
        |  | 
        
        | Term 
 
        | As chyme enters the duodenum: How digested are carbohydrates? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | As chyme enters the duodenum: How digested are proteins? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | As chyme enters the duodenum: How digested are fats? |  | Definition 
 
        | No digestion has taken place |  | 
        |  | 
        
        | Term 
 
        | What is the main function of the colon? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the large intestine dividied into? |  | Definition 
 
        | the cecum, appendix, colon, rectum, and anal canal |  | 
        |  | 
        
        | Term 
 
        | Where does the saclike cecum lay? |  | Definition 
 
        | below the ileocecal valve in the right iliac fossa |  | 
        |  | 
        
        | Term 
 
        | What does the cecum contain? |  | Definition 
 
        | A wormlike vermiform appendix |  | 
        |  | 
        
        | Term 
 
        | Features of the large intestine |  | Definition 
 
        | Tenia coli, haustra, epiploic appendages |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | three bands of longitudinal smooth muscle in its muscularis |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | pocketlike sacs caused by the tone of the teniae coli |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | fat-filled pouches of visceral peritoneum |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, and sigmoid colon |  | 
        |  | 
        
        | Term 
 
        | What does the sigmoid colonjoin? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What segment opens to the exterior at the anus? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Function of the rectal valves |  | Definition 
 
        | stop feces from being passed with gas |  | 
        |  | 
        
        | Term 
 
        | Two sphincters of the anus |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Internal sphincter composed of what? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Role of the internal sphincter |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Role of the external sphincter |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | External anal sphincter composed of what? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | When are the anal sphincters not closed? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What do the bacterial flora of the large intestine consist of? |  | Definition 
 
        | Bacteria surviving the small intestine that enter the cecum and those entering via the anus |  | 
        |  | 
        
        | Term 
 
        | What do bacterial flora do? |  | Definition 
 
        | Colonize the colon. Ferment indigestible carbohydrates. Release irritating acids and gases (flatus) synthesize B complex vitamins and vitamin K |  | 
        |  | 
        
        | Term 
 
        | Functions of the large intestine: Digestion |  | Definition 
 
        | Digestion of enteric bacteria, no further digestion takes place |  | 
        |  | 
        
        | Term 
 
        | Functions of the large intestine: Vitamins, minerals, and electrolytes |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Large intestine: Major function |  | Definition 
 
        | Propulsion of fecal material toward teh anus |  | 
        |  | 
        
        | Term 
 
        | Motility of the Large Intestine: Haustral Contractions |  | Definition 
 
        | Slow segmenting movements that move the contents of the colon. Haustra sequentially contract as they are stimulated by distension |  | 
        |  | 
        
        | Term 
 
        | Motility of the Large Intestine: Presence of food in the stomach |  | Definition 
 
        | Activates the gastrocolic reflex. Initiates peristalsis that forces contents toward the rectum |  | 
        |  |