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Chapter 22 - The Respiratory System
Human Anatomy and Physiology by Elaine Marieb
81
Anatomy
Undergraduate 1
11/19/2012

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Term
Pulmonary ventilation
Definition
Breathing; consists of inspiration and expiration
Term
External respiration
Definition
Oxygen diffuses from the lungs to the blood and carbon dioxide diffuses from the blood to the lungs
Term
Internal respiration
Definition
Exhange of gases between blood and tissue fluid and between tissue fluid and cells
Term
Nares
Definition
Nostrils
Term
Nasal septum
Definition
Divides the naval cavity; Formed anteriorly by the septal cartilage and posteriorly by the vomer bone and perpendicular plate of the ethmoid bone
Term
Intrapulmonary pressure
Definition
(P pul) pressure in the alveoli. It rises and falls with the phases of breathing, but it always equalizes with the atmospheric pressure eventually.
Term
Intrapleural pressure
Definition
(P ip) pressure in the pleural cavity. Fluctuates with breathing phases, but is always about 4 mm Hg less than P pul. That is P ip is always negative relative to P pul
Term
Atmospheric pressure
Definition
Force that air exerts on the surface of the body (760mm Hg at sea level)
Term
Transpulmonary pressure
Definition
The difference between the intrapulmonary and intrapleural pressures (Ppul - Pip) that keeps the air spaces of the lungs open, ie. keeps the lungs from collapsing
Term
Boyle's law
Definition
states that when the temperature is constant the pressure of gas varies inversely with its volume.
Term
Inspiration
Definition
air moving into the lungs
Term
Expiration
Definition
air moving out of the lungs
Term
Surfactant
Definition
secretion produced by certain cells of the alveoli that reduces the surface tension of water molecules thus preventing the collapse of the alveoli after each expiration
Term
Tidal volume (TV)
Definition
respiratory volume - during normal, quiet breathing about 500ml of air moves into and then out of the lungs with each breath.
Term
Inspiratory reserve volume (IRV)
Definition
the amount of air that can be inspired forcibly beyond the tidal volume (2100 - 3200ml)
Term
Expiratory reserve volume (ERV)
Definition
the amount of air normally 100-1200 ml that can be expelled from the lungs after a normal tidal volume expiration
Term
Residual volume (RV)
Definition
amount of air remaining in lungs even after the most strenuous expiration - about 1200 ml. This helps to keep the alveoli patent (open) and prevent lung collapse
Term
Inspiratory capacity (IC)
Definition
the total amount of air that can be inspired after a normal tidal volume expiration; TV + IRV
Term
Functional residual capacity (FRC)
Definition
represents the amount of air remaining in the lungs after a normal tidal volume expiration; RV + ERV
Term
Vital capacity (VC)
Definition
total amount of exchangeable air. TV + IRV + ERV. Approximately 4800 ml in healthy young males.
Term
Total lung capacity (TLC)
Definition
sum of all lung volumes and is normally aroung 6,000 ml
Term
Anatomical dead space
Definition
volume of inspired air that fills the conducting respiratory passageways and never contributes to gas exhange in the alveoli - amounts to approx. 150ml
Term
Spirometer
Definition
a small electronic device which measures various lung volumes and capacities.
Term
Minute ventilation
Definition
the total amount of gas that flows into or out of the respiratory track in one minute. Usually about 6L/minute
Term
Forced vital capacity (FVC)
Definition
Measures the amount of gas expelled when a subject takes a deep breath and the forcefully exhales maximally and as rapidly as possible.
Term
Dalton's law
Definition
states that the total pressure exerted by a mixture of gases is the sum of the pressures exerted independently by each gas in the mixture
Term
Henry's law
Definition
states that when a gas is in contact with a liquid the gas will dissolve in the liquid in proportion to its partial pressure
Term
Oxyhemoglobin
Definition
osygen-bound form of hemoglobin/ oxygen binds to iron
Term
Deoxyhemoglobin
Definition
hemoglobin that has released oxygen; Reduced hemoglobin.
Term
Abdominal thrust maneuver
Definition
a first aid procedure used to treat choking. The patient's diaphragm is pressured by the performer's thumb knuckle to expel air and thereby dislodging the obstruction in the windpipe.
Term
Adult respiratory distress syndrome(AARDS)
Definition
a dangerous lung condition that can develop after severe illness or injury to the body. Neutrophils leave the body's capillaries in large numbers and then secrete chemicals that increase capillary permeability. The capillary rich lungs are heavily affected. As the lungs fill with fluid the patient suffocates. Even with mechanical ventilation it is hard to control and often lethal.
Term
Adenoidectomy
Definition
surgical removal of an infected pharyngeal tonsil (adenoids)
Term
Apnea
Definition
Breathing cessation
Term
Asbestosis
Definition
a lung disease resulting from the inhalation of asbestos particles
Term
Asphyxia
Definition
a condition arising when the body is deprived of oxygen, causing unconsciousness or death; (suffocation, asphyxy - asphyxiation)
Term
Aspiration
Definition
(1) Inhaling or drawing something into the lungs or respiratory passages. Pathological aspiration -drawing vomit or excessive mucus into the lungs - may occur when a person is unconscious or anesthetized: turning the head to one side is preventive. (2) with drawing fluid by suction (use of an aspirator) done during surgery to keep an area free of blood and other body fluids; mucus is aspirated from the trachea of tracheotomy patients.
Term
Asthma
Definition
characterized by episodes of coughing, dyspena, wheezing and chest tightness - alone or in combination.
Term
Black lung disease
Definition
anthracosis: lung disease caused by inhaling coal dust.
Term
Bronchitis
Definition
a condition in which the bronchial tubes become inflamed. These tubes carry air to your lungs. People with this often have a cough that brings up mucus. Mucus is a slimy substance made by the lining of the bronchial tubes. It may also cause wheezing (a whistling or squeaky sound when you breathe), chest pain or discomfort, a low fever and shortness of breath.
Term
Bronchogenic carcinoma
Definition
lung cancer.
Term
Bronchoscopy
Definition
use of a viewing tube inserted through the nose or mouth to examine the internal surface of the main bronchi in the lung. Forceps attached to the tip of the tube can remove trapped objects or take samples of mucus for examination.
Term
Cheyne-Stokes breathing
Definition
abnormal breathing pattern sometimes seen just before death (death rattle) and in people with combined neurological and cardiac disorders.
Term
Chronic obstructive pulmonary disease (COPD)
Definition
Emphysema and chronic bronchitis - an irreversible decrease in the ability to force air out of the lungs.
Term
Coryza
Definition
profuse discharge from the mucous membrane of the nose; runny nose.
Term
Cystic fibrosis
Definition
genetic disorder in which secretion of overly viscous mucus clogs the respiratory passages, predisposes to fatal respiratory infection.
Term
Deviated septum
Definition
condition in which the nasal septum takes a more lateral course than usual and may obstruct breathing; often manifests in old age or from nose trauma.
Term
Dyspnea
Definition
difficult or labored breathing; air hunger.
Term
Emphysema
Definition
distinguished by permanent enlargement of the alveoli, accompanied by destruction of the alveolar walls.
Term
Endotracheal tube
Definition
a thin plastic tube threaded into the trachea through the nose or mouth; used to deliver oxygen to patients who are breathing inadequately, in a coma, or under anesthesia.
Term
Epistaxis
Definition
Nosebleed; commonly follows trauma to the nose or excessive nose blowing.
Term
Histotoxic hypoxia
Definition
occurs when body cells are unable to use oxygen even though adequate amounts are delivered.
Term
Hypoventilation
Definition
a decrease in the depth and rate of breathing characterized by an increase in blood carbon dioxide.
Term
Hypoxemic hypoxia
Definition
indicated by reduced arterial oxygen pressure.
Term
Hypoxia
Definition
condition in which inadequate oxygen is available to tissues.
Term
Infant respiratory distress syndrome (IRDS)
Definition
too little surfactant is present, causing surface tension to collapse the avleoli; peculiar to premature babies.
Term
Influenza
Definition
a viral infection that affects mainly the nose, throat, bronchi and, occasionally, lungs. Infection usually lasts for about a week, and is characterized by sudden onset of high fever, aching muscles, headache and severe malaise, non-productive cough, sore throat and rhinitis.
Term
Ischemic hypoxia
Definition
results from impaired or blocked blood circulation. stagnant
Term
Lung cancer
Definition
leading cause of cancer death in North America.
Term
Mechanical ventilation
Definition
mechanically assisted breathing.
Term
Nasal polyps
Definition
mushroomlike benign growths of the nasal mucosa; sometimes caused by infections, but most often cause is unknown. May block air flow.
Term
Orthopnea
Definition
inability to breathe in the horizontal (lying down) position.
Term
Otorhinolaryngology
Definition
branch of medicine that deals with diagnosis and treatment of diseases of the ears, nose, and throat.
Term
Pneumonia
Definition
infectious inflammation of the lungs, in which fluid accumulates in the alveoli; the 8th most common cause of death in the US.
Term
Pulmonary edema
Definition
leakage of fluid into the air sacks and tissue of the lungs.
Term
Pulmonary embolism
Definition
obstruction of the pulmonary artery or one of its branches by an embolus (most often a blood clot that has been carried from the lower limbs and through the right side of the heart into the pulmonary circulation). Symptoms are chest pain, productive bloody cough, tachycardia, and rapid, shallow, breathing.
Term
Pulmonary fibrosis
Definition
formation or development of excess fibrous connective tissue in the lungs; "scarring of the lung".
Term
Pertussis
Definition
whooping cough; a disease of the respiratory mucous membrane.
Term
Rales
Definition
an abnormal ratling sound heard when examining unhealthy lungs.
Term
Respirator
Definition
an apparatus used to induce artificial respiration.
Term
Rhinitis
Definition
inflammation of the nasal mucosa accompanied by excessive mucus production, nasal congestion, and postnasal drip.
Term
Severe acute respiratory syndrome (SARS)
Definition
a serious, potentially life-threatening viral infection caused by a previously unrecognized virus from the Coronaviridae family.
Term
Sinusitis
Definition
inflamed sinuses.
Term
Sleep apnea
Definition
cessation of breathing temporarily during sleep.
Term
Sputum
Definition
a mixture of saliva and mucus coughed up from the respiratory tract.
Term
Strep throat
Definition
an infection of the oral pharynx and tonsils by streptococcus.
Term
Stuttering
Definition
a problem of voice production in which the first syllable of words is repeated in "machine-gun" fashion.
Term
Sudden infant death syndrome (SIDS)
Definition
unexpected death of an apparently healthy infant during sleep.
Term
Tachypnea
Definition
abnormally rapid breathing.
Term
Tracheotomy
Definition
surgical opening of the trachea; done to provide an alternate route for air to reach the lungs when more superior respiratory passageways are obstructed (as by food or a crushed larynx).
Term
Tuberculosis (TB)
Definition
infectious disease spreadby coughing and primarily enters the body in inhaled air.
Term
Wheeze
Definition
a continuous, coarse, whistling sound produced in the respiratory airways during breathing, as a result of obstruction in the air passages.
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