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CHAPTER 2
Cells: the living units
48
Anatomy
Undergraduate 1
03/13/2010

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Term
plasma membrane (plasmalemma)
Definition
outer cell membrane; thin, flexible layer.
Term
integral proteins
Definition
firmly embedded in or strongly attached to lipid bilayer
Term
peripheral proteins
Definition
not embedded in lipid bilayer at all, attach rather loosely to membrane surface
Term
receptors
Definition
membrane proteins that have ability to bind to specific molecules arriving from outside the cell
Term
endocytosis
Definition
mechanism by which large particles and macromolecs enter cells
Term
clathrin
Definition
invagination is called a coated pit in reference to a covering on this protein found on the cytoplasmic face of vesicle
Term
phagocytosis
Definition
"cell eating":
pseudopods protrude and flow around some large material, engulf it
Term
phagosome
Definition
membranous vesicle that engulfs bacteria/debris
Term
pinocytosis (fluid-phase endocytosis)
Definition
"cell drinking":
sampling extracellular fluid
Term
receptor-mediated endocytosis
Definition
exquisitely selective transport process, brings some molecules into cells
Term
caveolae
Definition
other proteins in endocytosis, flasklike inpocketings of the plasma membrane
Term
exocytosis
Definition
mechanism by which substances move from cytoplasm to the outside of the cell.
Term
cytoplasm
Definition
"cell-forming material" -- part of cell that lies internal to the plasma membrane and external to the nucleus
Term
cytosol or cytoplasmic matrix
Definition
jelly-like, fluid-containing substance within which other cytoplasmic elements are suspended.
Term
ribosomes
Definition
assembly line of the manufacturing plan, producing proteins for cellular or extracellular function. (proteins + rRNA)
Term
messenger RNA
Definition
dictates genetic material to the ribosomes (messenger molecules)
Term
free ribosomes
Definition
float freely in cytosol; make the soluble proteins that function within the cytosol itself
Term
endoplasmic reticulum
Definition
a system of membranous envelopes and tubes in the cytoplasm of a cell
Term
rough endoplasmic reticulum
Definition
consists of cisternae...
it's in glad cells (secrete large amounts of protein);
makes digestive enzymes;
makes both integral proteins and phosopholipid molecs of cell's membranes;
"Membrane factory"
Term
cisternae
Definition
stacked envelopes,"fluid-filled cavities"
Term
smooth endoplasmic reticulum
Definition
consists of tubules arranged in branching network;
makes or breaks up fats
Term
Golgi apparatus
Definition
stack of 3-10 disc-shaped envelopes, each bound by a membrane;
sorts, processes, and packages proteins and membranes from rER
Term
cis-Golgi network
Definition
receives spherical, membranous transport vesicles from rER
Term
trans-Golgi network
Definition
vesicles bud off from here to leave apparatus
Term
secretory vesicles (secretory granules)
Definition
pathway 1: gland cells:
contains protein product, ultimately release contents to cell's exterior
Term
lysosomes
Definition
spherical, membrane-walled sacs containing digestive enzymes;
intracellular digestion
Term
mitochonria
Definition
rodlike, double-membrane structures; inner membrane flded into projections called cristae;
site of ATP synthesis
Term
peroxisomes
Definition
membranous sacs of oxidase enzymes;
detoxify number of toxic substances;
catalase breaks down Hydrogen peroxide
Term
microtubules
Definition
cylindrical structures made of tubulin proteins;
supports cells and gives it shape;
involved in intra and cellular movements;
forms centrioles
Term
microfilaments
Definition
fine filaments of contractile protein actin;
involved in muscle contraction and other types of intracell movement;
help form cell's cytoskeleton
Term
intermediate flaments
Definition
protein fibers;
stable cytoskeletal elements, resist tension forces acting on the cell
Term
centrioles
Definition
paired cylindrical bodies, each composed of nine triplets of microtubules;
organize microtubule network during mitosis to form spindle and asters;
form bases of cilia and flagella
Term
nucleus
Definition
surrounded by nuclear envelope; contains fluid nucleoplasm, nucleoli, chromatin;
responsible for transmitting genetic info and providing instructions for protein synthesis
Term
nuclear envelope
Definition
double-membrane struction, pierced with pores, continuous w cytoplasmic ER;
separates nucleplasm from cytoplasm and regulates passage of substances to and from nucleus
Term
nucleoli
Definition
dense spherical (non-membrane-bounded) bodies;
site of ribosome subunit manufature
Term
chromatin
Definition
granular, threadlike material composed of DNA and histone proteins;
DNA constitutes the genes
Term
free-radicals
Definition
agressively reactive molecules, peroxisomes neutralize them to hydrogen peroxide
can destroy cell's proteins, membranes, and DNA
Term
cytoskeleton
Definition
elaborate network of rods running throughout cytosol.
Term
unconventional myosin
Definition
actin filaments interact with this protein to generate contractile forces within cell
Term
centrosome matrix
Definition
outer cloud of protein with centrosome
Term
glycosomes
Definition
store sugar in form of glycogen, which is a long branching chain of glocose molecules, cell's main energy source
Term
DNA
Definition
genetic material, direct's cell's activities by providing instructions for protein synthesis
Term
nuclear lamina
Definition
lines inner membrane of nuclear envelope; protein filaments which maintain shape of nucleus
Term
nucleoli
Definition
in the cell nucleus, dark-staining bodies
Term
transcription
Definition
extended chromatin is where DNA's genetic code is copied onto messenger RNA molecs in this process
Term
histone
Definition
in clusters of eight; disc-shaped protein molecules;
DNA helix wraps around these clusters
Term
nucleosome
Definition
each cluster of DNA and histones
Term
chromosomes
Definition
highest level of chromatin organization....contains single, very long molecule of DNA
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