| Term 
 
        | The Lymphatic Elaborate system of (6) which run throughout the body
 |  | Definition 
 
        | The Lymphatic Elaborate system of lymphoid organs,  nodes, ducts, tissues, capillaries and  vessels which run throughout the body
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        | Term 
 
        | Collect fluid - lymph - from ____ tissue around blood  capillaries |  | Definition 
 
        | Collect fluid - lymph - from loose  connective tissue around blood  capillaries |  | 
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        | Term 
 
        | Carry lymph to _____ Lymph flows only towards the ____
 Carry fluid to great veins in the ___
 Lymphatic vessels one way system
 |  | Definition 
 
        | Carry lymph to greater veins Lymph flows only towards the heart
 Carry fluid to great veins in the neck
 Lymphatic vessels one way system
 |  | 
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        | Term 
 
        | Functions of Lymphatic System Removal of excess _____ from body tissues
 Absorption of ____ and transport of fat as ___ to the circulatory system
 Production of immune cells such as ____
 Blood capillaries are surrounded by ____ tissue that contain tissue fluid - ____
 |  | Definition 
 
        | Functions of Lymphatic System Removal of excess fluids from body tissues
 Absorption of fatty acids and transport of fat as chyle to the circulatory system
 Production of immune cells such as lymphocytes
 Blood capillaries are surrounded by loose connective tissue hat contain tissue fluid - lymph
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        | Term 
 
        | Lymph arises from ____ filtered through capillary walls Lymph consists of:
 (5)
 Return tissue ___ and blood ____ to bloodstream
 Blockage of lymphatic vessels - ____
 |  | Definition 
 
        | Lymph arises from blood filtered through capillary walls Lymph consists of:
 Small molecules, water, ions, CO2/O2, nutrients
 Return tissue fluid and blood proteins to bloodstream
 Blockage of lymphatic vessels - edema
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        | Term 
 
        | Orders of Lymphatic Vessels Lymph _____ – smallest – first receive lymph
 Lymphatic ____ – collect from lymph capillaries
 Lymph ____ – scattered along collecting vessels
 Lymph _____ – collect lymph from collecting vessels
 Lymph ____ – empty into veins of the neck
 |  | Definition 
 
        | Orders of Lymphatic Vessels Lymph capillaries – smallest – first receive lymph
 Lymphatic collecting vessels – collect from lymph capillaries
 Lymph nodes – scattered along collecting vessels
 Lymph trunks – collect lymph from collecting vessels
 Lymph ducts – empty into veins of the neck
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        | Term 
 
        | Lymph Capillaries Located near _____ capillaries
 Widespread, almost everywhere blood capillaries occur
 Receive tissue fluid from connective tissue
 Increased volume of tissue fluid
 ____ flaps open and allow fluid to enter
 High permeability allows:
 Uptake of tissue fluid
 Entrance of bacteria, viruses, and cancer cells can travel throughout the body. Can be averted partially with lymph ___ which destroy most pathogens
 |  | Definition 
 
        | Lymph Capillaries Located near blood capillaries
 Widespread, almost everywhere blood capillaries occur
 Receive tissue fluid from connective tissue
 Increased volume of tissue fluid
 Minivalve flaps open and allow fluid to enter
 High permeability allows:
 Uptake of tissue fluid
 Entrance of bacteria, viruses, and cancer cells can travel throughout the body. Can be averted partially with lymph nodes which destroy most pathogens
 |  | 
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        | Term 
 
        | Lymph Capillaries _____  – specialized lymphatic  capillaries
 Located in the ___ of the small  intestines
 Receive digested ___
 Fatty lymph – ___
 |  | Definition 
 
        | Lymph Capillaries Lacteals  – specialized lymphatic  capillaries
 Located in the villi of the small  intestines
 Receive digested fats
 Fatty lymph – chyle
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        | Term 
 
        | From lymph capillaries, lymph enters lymphatic ______ Accompany blood vessels
 Superficial collecting vessels in the skin travel with superficial ___
 Deep one from trunk and digestive viscera travel with deep _____
 Narrow and delicate
 Composed of the same three ____ as blood vessels, but wall thinner because lymph flows under low ____ - not connected to the heart
 |  | Definition 
 
        | From lymph capillaries, lymph enters lymphatic collecting vessels Accompany blood vessels
 Superficial collecting vessels in the skin travel with superficial veins
 Deep one from trunk and digestive viscera travel with deep arteries
 Narrow an delicate
 Composed of the same three tunics as blood vessels, but wall thinner because lymph flows under low pressure - not connected to the heart
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        | Term 
 
        | Lymphatic Collecting Vessels To direct flow, they contain more ___ than veins
 At the base of each ___, vessel ____, forms a pocket in which lymph collects
 Forces ___ to close
 Looks like a string of beads
 Lymph propelled by __ mechanisms than blood :
 Bulging of ____ muscles
 Pulsing of nearby ______
 Tunica ____ of the lymph vessels contracts
 Very slow and weak lymph flow - ___
 |  | Definition 
 
        | Lymphatic Collecting Vessels To direct flow, they contain more valves than veins
 At the base of each valve, vessel bulges, forms a pocket in which lymph collects
 Forces valves to close
 Looks like a string of beads
 Lymph propelled by weaker mechanisms than blood :
 Bulging of skeletal muscles
 Pulsing of nearby arteries
 Tunica media of the lymph vessels contracts
 Very slow and weak lymph flow - edema
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        | Term 
 
        | Lymph Nodes Cleanse the lymph of _____
 Situated along the lymphatic collecting  _____
 Human body contains approximately  ___ nodes , 1-25mm
 Lymph nodes are organized in clusters
 |  | Definition 
 
        | Lymph Nodes Cleanse the lymph of pathogens
 Situated along the lymphatic collecting  vessels
 Human body contains approximately  500 nodes , 1-25mm
 Lymph nodes are organized in clusters
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        | Term 
 
        | ___ nodes: superficial, along the jugular veins and carotid arteries, ____ nodes: armpit ____ nodes: superior thigh, filters lymph from upper and lower limbs
 _____ nodes: deep, in the mediastinum, filter lymph from thoracic viscera
 ____ nodes: deep, along abdominal aorta, filter lymph from posterior abdominal wall
 ____ nodes: deep, along the iliac arteries, filter lymph from pelvic organs and lower limbs
 |  | Definition 
 
        | Cervical nodes: superficial, along the jugular veins and carotid arteries, receives lymph from the head and neck Axillary nodes: armpit
 Inguinal nodes: superior thigh, filters lymph from upper and lower limbs
 Tracheobronchial nodes: deep, in the mediastinum, filter lymph from thoracic viscera
 Aortic nodes: deep, along abdominal aorta, filter lymph from posterior abdominal wall
 Iliac nodes: deep, along the iliac arteries, filter lymph from pelvic organs and lower limbs
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        | Term 
 
        | Lymph Trunks Large lymphatic collecting vessels  converge into:
 Five major lymph trunks
 ____ trunk  – receives lymph from  lower limbs
 _____ trunk  – receives chyle from  digestive organs
 ______ trunk  – collects  lymph from thoracic viscera
 ______ trunk  – receive lymph from  upper limbs and thoracic wall
 ______ trunk  – drain lymph from the  head and neck
 |  | Definition 
 
        | Lymph Trunks Large lymphatic collecting vessels  converge into:
 Five major lymph trunks
 Lumbar trunk  – receives lymph from  lower limbs
 Intestinal trunk  – receives chyle from  digestive organs
 Bronchomediastinal trunk  – collects  lymph from thoracic viscera
 Subclavian trunk  – receive lymph from  upper limbs and thoracic wall
 Jugular trunk  – drain lymph from the  head and neck
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        | Term 
 
        | Lymph Ducts Lymph trunks drain into the largest  lymphatic vessels: the lymph ducts
 ____ duct – ascends along vertebral  bodies
 Drains three quarters of the body
 right lymphatic duct
 Empties into right internal ____ and  ____ veins
 |  | Definition 
 
        | Lymph Ducts Lymph trunks drain into the largest  lymphatic vessels: the lymph ducts
 Thoracic duct – ascends along vertebral  bodies
 Drains three quarters of the body
 Right lymphatic duct
 Empties into right internal jugular and  subclavian veins
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        | Term 
 
        | The Immune System Recognizes specific foreign molecules
 Destroys pathogens effectively
 Key cells – ______
 Also includes ___ tissue and ___ organs
 |  | Definition 
 
        | The Immune System Recognizes specific foreign molecules
 Destroys pathogens effectively
 Key cells – lymphocytes
 Also includes lymphoid tissue and lymphoid organs
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        | Term 
 
        | Lymphocytes – compose ____% of WBCs The most important cells of the immune system
 Nucleus – stains ____ and occupies __ of the cytoplasm
 Function mainly outside of the blood vessels in connective tissues
 Effective in fighting infectious organisms
 Act against a specific foreign molecule (____)
 Two classes attack antigens in different ways
 T cells
 B cells
 |  | Definition 
 
        | Lymphocytes – compose 20–45% of WBCs The most important cells of the immune system
 Nucleus – stains dark purple occupies most of the cytoplasm
 Function mainly outside of the blood vessels in connective tissues
 Effective in fighting infectious organisms
 Act against a specific foreign molecule (antigen)
 Two classes attack antigens in different ways
 T cells
 B cells
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        | Term 
 
        | Lymphocyte Activation Lymphocytes
 Infectious organisms attacked by inflammatory response
 Macrophages, then _____
 B lymphocytes – become _____ cells
 Secrete _____
 Cytotoxic T lymphocytes
 Destroy ____-bearing cells
 |  | Definition 
 
        | Lymphocyte Activation Lymphocytes
 Infectious organisms attacked by inflammatory response
 Macrophages, then lymphocytes
 B lymphocytes – become plasma cells
 Secrete antibodies
 Cytotoxic T lymphocytes
 Destroy antigen-bearing cells
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        | Term 
 
        | Lymphocyte Activation Lymphoid Tissue
 Most important tissue of the immune system
 Two general locations
 ____ membranes of:
 Digestive, urinary, respiratory, and reproductive tracts
 Mucosa-associated lymphoid tissue (____)
 Lymphoid organs
 |  | Definition 
 
        | Lymphocyte Activation Lymphoid Tissue
 Most important tissue of the immune system
 Two general locations
 Mucous membranes of:
 Digestive, urinary, respiratory, and reproductive tracts
 Mucosa-associated lymphoid tissue (MALT)
 Lymphoid organs
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        | Term 
 
        | Lymphoid Organs Designed to gather and destroy infectious microorganisms
 Thymus
 Immature lymphocytes develop into _____
 
 Most active in childhood
 Functional tissue atrophies with age
 |  | Definition 
 
        | Lymphoid Organs Designed to gather and destroy infectious microorganisms
 Thymus
 Immature lymphocytes develop into T  lymphocytes
 
 Most active in childhood
 Functional tissue atrophies with age
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        | Term 
 
        | Lymph Nodes Function
 Lymph percolates through lymph ____
 Most antigenic challenges occur in lymph nodes
 Antigens destroyed – and activate ______
 |  | Definition 
 
        | Lymph Nodes Function
 Lymph percolates through lymph sinuses
 Most antigenic challenges occur in lymph nodes
 Antigens destroyed – and activate B and T lymphocytes
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        | Term 
 
        | Spleen Largest lymphoid organ
 Two main blood-cleansing functions
 Removal of blood-borne _____
 Removal and destruction of  _______
 Site of _____ in the fetus
 |  | Definition 
 
        | Spleen Largest lymphoid organ
 Two main blood-cleansing functions
 Removal of blood-borne antigens
 Removal and destruction of  old/defective blood cells
 Site of hematopoiesis in the fetus
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        | Term 
 
        | Tonsils Simplest lymphoid organs
 Four groups of tonsils (4) tonsils
 Arranged in a ring to gather and remove  pathogens
 |  | Definition 
 
        | Tonsils Simplest lymphoid organs
 Four groups of tonsils
 Palatine, lingual, pharyngeal, and tubal  tonsils
 Arranged in a ring to gather and remove  pathogens
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        | Term 
 
        | Aggregated Lymphoid Nodules and the Appendix ___ (in the ______)– abundant in walls of intestines
 Fight invading bacteria
 Generate a wide variety of ____  lymphocytes
 Appendix - tubular offshoot of the  ___
 |  | Definition 
 
        | Aggregated Lymphoid Nodules and the Appendix MALT (in the lamina propria)– abundant in walls of intestines
 Fight invading bacteria
 Generate a wide variety of memory  lymphocytes
 Appendix - tubular offshoot of the  cecum
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