| Term 
 
        | Location and Orientation within the Thorax Heart – weighs 250–__ grams  cone-shaped, oblique position
 ___est organ of the mediastinum
 Located between the lungs
 Posterior to the sternum
 Apex lies to the ___ of the midline
 Base is the broad _____ surface
 |  | Definition 
 
        | Location and Orientation within the Thorax Heart – weighs 250–350 grams  cone-shaped, oblique position
 Largest organ of the mediastinum
 Located between the lungs
 Posterior to the sternum
 Apex lies to the left of the midline
 Base is the broad posterior surface
 |  | 
        |  | 
        
        | Term 
 
        | The Heart A muscular double pump
 Pulmonary circuit – takes blood to and from the ___
 Systemic circuit – vessels transport blood to and from _____
 Atria – receive blood from the ___ and ____ circuits
 Ventricles – the ____ chambers of the heart
 |  | Definition 
 
        | The Heart A muscular double pump
 Pulmonary circuit – takes blood to and from the lungs
 Systemic circuit – vessels transport blood to and from body tissues
 Atria – receive blood from the pulmonary and systemic circuits
 Ventricles – the pumping chambers of the heart
 |  | 
        |  | 
        
        | Term 
 
        | The Pulmonary and Systemic Circuits Four “Corners” of the Heart
 Superior right point – at costal cartilage of ____ rib and sternum
 Inferior right point– at costal cartilage of ___ rib lateral to the sternum
 Superior left point– at costal cartilage of ___ rib lateral to the sternum
 Inferior left point– lies in the ____ intercostal space at the ____ line
 |  | Definition 
 
        | The Pulmonary and Systemic Circuits Four “Corners” of the Heart
 Superior right point – at costal cartilage of third rib and sternum
 Inferior right point– at costal cartilage of sixth rib lateral to the sternum
 Superior left point– at costal cartilage of second rib lateral to the sternum
 Inferior left point– lies in the fifth intercostal space at the midclavicular line
 |  | 
        |  | 
        
        | Term 
 
        | Structure of the Heart – Layers of the Heart Wall ______:
 Visceral layer of the serous pericardium
 _______:
 Consists of cardiac muscle
 Muscle arranged in circular and spiral patterns
 ________:
 Endothelium resting on a layer of connective tissue
 Lines the internal walls of the heart;
 chamber lining & valves
 |  | Definition 
 
        | Structure of the Heart – Layers of the Heart Wall Epicardium
 Visceral layer of the serous pericardium
 Myocardium
 Consists of cardiac muscle
 Muscle arranged in circular and spiral patterns
 Endocardium
 Endothelium resting on a layer of connective tissue
 Lines the internal walls of the heart;
 chamber lining & valves
 |  | 
        |  | 
        
        | Term 
 
        | Pericardium -around the heart ____ layer sac that encloses the heart Fibrous pericardium – ___ layer. Strong layer of __ connective tissue.Adheres to diaphragm inferiorly. Holds the heart in place, prevents _____
 Serous pericardium – formed from ___ layers
 Outer layer parietal layer of the ___ pericardium
 Visceral layer of the serous pericardium or ___. Lies on the heart. Considered as part of the heart
 Pericardial cavity slit like space between ___ and ___ pericardium
 Lubricating film of serous fluid. Reduces friction of beating heart and outer wall of pericardial sac
 |  | Definition 
 
        | Pericardium -around the heart tripled layer sac that encloses the heart Fibrous pericardium – outer layer. Strong layer of dense connective tissue.Adheres to diaphragm inferiorly. prevents overstretching. Holds the heart in place
 Serous pericardium – formed from two layers
 Outer layer parietal layer of the serous pericardium
 Visceral layer of the serous pericardium or epicardium. Lies on the heart. Considered as part of the heart
 Pericardial cavity slit like space between fibrous and serous pericardium
 Lubricating film of serous fluid. Reduces friction of beating heart and outer wall of pericardial sac
 |  | 
        |  | 
        
        | Term 
 
        | Walls differ in thickness Atria – ___ walls
 Ventricles – ____ walls
 |  | Definition 
 
        | Walls differ in thickness Atria – thin walls
 Ventricles – thick walls
 |  | 
        |  | 
        
        | Term 
 
        | Left ventricle – three times ____ than right Exerts ____ pumping force
 Flattens right ventricle into a ____ shape
 |  | Definition 
 
        | Left ventricle – three times thicker than right Exerts more pumping force
 Flattens right ventricle into a crescent shape
 |  | 
        |  | 
        
        | Term 
 
        | Internal divisions Two atria and two ventricles
 Inter___ and inter_____ septa (septum)
 |  | Definition 
 
        | Internal divisions Two atria and two ventricles
 Interventricular and interatrial septa (septum)
 |  | 
        |  | 
        
        | Term 
 
        | External markings ___ sulcus; between the atria and the ventricles
 ______ sulcus; anterior position of the interventricular septum between the two _______ sulcus; separates the two ventricles on inferior surface of the heart
 |  | Definition 
 
        | External markings Coronary sulcus; between the atria and the ventricles
 Anterior interventricular sulcus; anterior positionof the interventricular septum between the two ventricles
 Posterior interventricular sulcus; separates the two ventricles on inferiro surface of the heart
 |  | 
        |  | 
        
        | Term 
 
        | Right atrium receives O2-___ blood from the ____ circuit 3 veins - superior and inferior ____ ,+ ____ sinus
 Right auricle external
 Right ventricle receives blood from the right ___ and pumps it into the ___ circuit via the pulmonary ___ (artery)
 Externally it forms most of the ____ surface of the heart
 ____valve (atrioventricular valve) opening between atrium and ventricle
 ____ valve opening between the right ventricle and the pulmonary trunk
 |  | Definition 
 
        | Right atrium receives O2-poor blood from the systemic circuit 3 veins - superior and inferior vena cava (SVC IVC), coronary sinus
 Right auricle external
 Right ventricle receives blood from the right atrium and pumps it into the pulmonary circuit via the pulmonary trunk (artery)
 Externally it forms most of the anterior surface of the heart
 Tricuspid valve (atrioventricular valve) opening between atrium and ventricle
 Pulmonary valve opening between the right ventricle and the pulmonary trunk
 |  | 
        |  | 
        
        | Term 
 
        | Left atrium makes most of the heart ___ surface receives O2-___ blood from the __ via two right and two left ___ veins Left auricle
 ___ valve(atrioventricular) opening between atrium and ventricle
 Left ventricle forms the ____ of the heart. Pumps blood into the ___circuit via the aorta via the ____ valve (aortic valve)
 |  | Definition 
 
        | Left atrium makes most of the heart posterior surface receives O2-rich blood from the lungs via two right and two left pulmonary veins Left auricle
 Mitral valve(atrioventricular) opening between atrium and ventricle
 Left ventricle forms the apex of the heart. Pumps blood into the systemic circuit via the aorta via the semilunar valve (aortic valve)
 |  | 
        |  | 
        
        | Term 
 
        | Right Atrium Forms right border of heart
 Receives blood from ____ circuit
 _____ muscles
 Ridges inside anterior of right atrium
 _____ terminalis
 Landmark used to locate veins entering right atrium
 ____ ovalis
 Depression in interatrial septum
 Remnant of foramen ovale
 |  | Definition 
 
        | Right Atrium Forms right border of heart
 Receives blood from systemic circuit
 Pectinate muscles
 Ridges inside anterior of right atrium
 Crista terminalis
 Landmark used to locate veins entering right atrium
 Fossa ovalis
 Depression in interatrial septum
 Remnant of foramen ovale
 |  | 
        |  | 
        
        | Term 
 
        | ____ beats/minute at rest Systole – _______
 Diastole – ______
 Systole and diastole also refer to:
 Stage of heartbeat when ventricles contract and expand
 |  | Definition 
 
        | 70–80 beats/minute at rest Systole – contraction
 Diastole – expansion
 Systole and diastole also refer to:
 Stage of heartbeat when ventricles contract and expand
 |  | 
        |  | 
        
        | Term 
 
        | Heart Valves – Valve Structure Each valve composed of:
 _____ with connective tissue core
 ____ (AV) valves – between atria and ventricles
 ___ and ____ valves – at junction of ventricles and great arteries
 |  | Definition 
 
        | Heart Valves – Valve Structure Each valve composed of:
 Endocardium with connective tissue core
 Atrioventricular (AV) valves – between atria and ventricles
 Aortic and pulmonary valves – at junction of ventricles and great arteries
 |  | 
        |  | 
        
        | Term 
 
        | “Lub-dup” – sound of valves closing First sound “lub” – the ___ valves closing
 Second sound “dup” – the ____ valves closing
 |  | Definition 
 
        | “Lub-dup” – sound of valves closing First sound “lub” – the AV valves closing
 Second sound “dup” – the semilunar valves closing
 |  | 
        |  | 
        
        | Term 
 
        | Each valve sound – best heard near a different heart corner ____ valve – superior left corner
 ____ valve – superior right corner
 ____ (bicuspid) valve– at the apex
 ____ valve – inferior right corner
 |  | Definition 
 
        | Each valve sound – best heard near a different heart corner Pulmonary valve – superior left corner
 Aortic valve – superior right corner
 Mitral (bicuspid) valve– at the apex
 Tricuspid valve – inferior right corner
 |  | 
        |  | 
        
        | Term 
 
        | Fibrous Skeleton Surrounds all four valves
 Composed of dense connective tissue
 Functions
 Anchors valve cusps
 Prevents ____ of valve openings
 Main point of ____ for cardiac muscle
 Blocks direct spread of _____
 |  | Definition 
 
        | Fibrous Skeleton Surrounds all four valves
 Composed of dense connective tissue
 Functions
 Anchors valve cusps
 Prevents overdilation of valve openings
 Main point of insertion for cardiac muscle
 Blocks direct spread of electrical impulses
 |  | 
        |  | 
        
        | Term 
 
        | Conducting System Cardiac muscle tissue has intrinsic ability to:
 Generate and conduct __
 Signal these cells to ____ rhythmically
 Conducting system
 A series of specialized cardiac muscle cells
 ___ (SA) node sets the inherent rate of contraction
 |  | Definition 
 
        | Conducting System Cardiac muscle tissue has intrinsic ability to:
 Generate and conduct impulses
 Signal these cells to contract rhythmically
 Conducting system
 A series of specialized cardiac muscle cells
 Sinoatrial (SA) node sets the inherent rate of contraction
 |  | 
        |  | 
        
        | Term 
 
        | Heart rate is altered by external controls Nerves to the heart include:
 Visceral ____ fibers
 Parasympathetic branches of the ___nerve
 Sympathetic fibers – from ___ and upper thoracic chain _____
 |  | Definition 
 
        | Heart rate is altered by external controls Nerves to the heart include:
 Visceral sensory fibers
 Parasympathetic branches of the vagus nerve
 Sympathetic fibers – from cervical and upper thoracic chain ganglia
 |  | 
        |  | 
        
        | Term 
 
        | Blood Supply to the Heart Functional blood supply
 ___ arteries
 Arise from the ____
 Located in the ____ sulcus
 Main branches
 Left and right _____ arteries
 |  | Definition 
 
        | Blood Supply to the Heart Functional blood supply
 Coronary arteries
 Arise from the aorta
 Located in the coronary sulcus
 Main branches
 Left and right coronary arteries
 |  | 
        |  | 
        
        | Term 
 
        | The Heart Throughout Life Blood vessels
 Begin as condensations of mesodermal ____
 Embryonic heart
 Pair of __ fuse at day ___
 Heart starts pumping at day __
 ____develop along heart tube
 |  | Definition 
 
        | Blood Supply to the Heart The Heart Throughout Life
 Blood vessels
 Begin as condensations of mesodermal mesenchyme
 Embryonic heart
 Pair of tubes fuse at day 21
 Heart starts pumping at day 22
 Bulges develop along heart tube
 |  | 
        |  | 
        
        | Term 
 
        | The Heart in Adulthood and Old Age Age-related changes
 ____ and ____ of valve cusps
 Decline in cardiac ____
 ____ control over heart is less efficient
 Less severe in the physically active
 Fibrosis of cardiac muscle tissue
 Lowers the amount of___ the heart can pump
 |  | Definition 
 
        | The Heart in Adulthood and Old Age Age-related changes
 Hardening and thickening of valve cusps
 Decline in cardiac reserve
 Sympathetic control over heart is less efficient
 Less severe in the physically active
 Fibrosis of cardiac muscle tissue
 Lowers the amount of blood the heart can pump
 |  | 
        |  |