| Term 
 
        | Rostral – toward the ___ Caudal – toward the ____
 |  | Definition 
 
        | Rostral – toward the nose Caudal – toward the tail
 |  | 
        |  | 
        
        | Term 
 
        | Brain arises from the ___ part of the neural tube Three primary brain vesicles in 4-week embryo
 Prosencephalon – the _____
 Mesencephalon – the ______
 Rhombencephalon – the _____
 |  | Definition 
 
        | Brain arises from the rostral part of the neural tube Three primary brain vesicles in 4-week embryo
 Prosencephalon – the forebrain
 Mesencephalon – the midbrain
 Rhombencephalon – the hindbrain
 |  | 
        |  | 
        
        | Term 
 
        | Cortex – ____ layer of ____ matter Formed from neuronal cell ____
 Located in cerebrum and cerebellum
 |  | Definition 
 
        | Cortex – outer layer of gray matter Formed from neuronal cell bodies
 Located in cerebrum and cerebellum
 |  | 
        |  | 
        
        | Term 
 
        | Ventricles of the Brain Expansions of the brain’s ___ cavity
 Deep within the brain
 Filled with ____ fluid
 Lined with ____ cells
 Continuous with each other
 Continuous with the central canal of the spinal cord
 |  | Definition 
 
        | Ventricles of the Brain Expansions of the brain’s central cavity
 Deep within the brain
 Filled with cerebrospinal fluid
 Lined with ependymal cells
 Continuous with each other
 Continuous with the central canal of the spinal cord
 |  | 
        |  | 
        
        | Term 
 
        | _____ (pair)– located in cerebral hemispheres(called first and second in the past) Horseshoe-shaped from bending of the cerebral hemispheres
 ___ ventricle – lies in _______
 Connected with lateral ventricles by interventricular foramen
 _____ – connects 3rd and 4th ventricles
 Fourth ventricle – lies in ____, thin tube-like cavity
 Connects to the central canal of the spinal cord
 |  | Definition 
 
        | Lateral ventricles (pair)– located in cerebral hemispheres(called first and second in the past) Horseshoe-shaped from bending of the cerebral hemispheres
 Third ventricle – lies in diencephalon
 Connected with lateral ventricles by interventricular foramen
 Cerebral aqueduct – connects 3rd and 4th ventricles
 Fourth ventricle – lies in hindbrain, thin tube-like cavity
 Connects to the central canal of the spinal cord
 |  | 
        |  | 
        
        | Term 
 
        | The Cerebral Hemispheres Account for ___ of brain mass
 Fissures – deep grooves – separate major regions of the brain
 ____ fissure – separates cerebrum and cerebellum
 ____ fissure – separates cerebral hemispheres
 |  | Definition 
 
        | The Cerebral Hemispheres Account for 83% of brain mass
 Fissures – deep grooves – separate major regions of the brain
 Transverse fissure – separates cerebrum and cerebellum
 Longitudinal fissure – separates cerebral hemispheres
 |  | 
        |  | 
        
        | Term 
 
        | The Cerebral Hemispheres ____ – grooves on the surface of the cerebral hemispheres ____ – twisted ridges between ___ Prominent ___ and ___ are similar in all people Deeper sulci divide cerebrum into lobes Lobes are named for the skull bones overlying them ____ sulcus separates frontal and parietal lobes |  | Definition 
 
        | The Cerebral Hemispheres Sulci – grooves on the surface of the cerebral hemispheres Gyri – twisted ridges between sulci Prominent gyri and sulci are similar in all people Deeper sulci divide cerebrum into lobes Lobes are named for the skull bones overlying them Central sulcus separates frontal and parietal lobes |  | 
        |  | 
        
        | Term 
 
        | Deep gray matter of the cerebrum (basal _____) |  | Definition 
 
        | Deep gray matter of the cerebrum (basal ganglia) |  | 
        |  | 
        
        | Term 
 
        | The Cerebral Cortex External ___ matter region of the cerebral hemispheres
 Home of our conscious mind
 Enables us to:
 Be aware of ourselves and our sensations
 Initiate and control ____ movements
 Communicate, remember, and understand
 Determines Intelligence・Determines Personality・Interpretation of Sensory Impulses・Motor Function・Planning and Organization・Touch Sensation
 Brodmann (1909) divided cortex into __ structurally different areas
 |  | Definition 
 
        | The Cerebral Cortex External gray matter region of the cerebral hemispheres
 Home of our conscious mind
 Enables us to:
 Be aware of ourselves and our sensations
 Initiate and control voluntary movements
 Communicate, remember, and understand
 Determines Intelligence・Determines Personality・Interpretation of Sensory Impulses・Motor Function・Planning and Organization・Touch Sensation
 Brodmann (1909) divided cortex into 52 structurally different areas
 |  | 
        |  | 
        
        | Term 
 
        | The Cerebral Cortex Composed of gray matter
 Neuronal cell ___, ____, and short ___ (no ____)
 Folds in cortex – triples its size
 Approximately __ of brain’s mass
 |  | Definition 
 
        | The Cerebral Cortex Composed of gray matter
 Neuronal cell bodies, dendrites, and short axons (no myelin)
 Folds in cortex – triples its size
 Approximately 40% of brain’s mass
 |  | 
        |  | 
        
        | Term 
 
        | Three kinds of functional areas ____ areas -control voluntary motor functions
 ____ areas - conscious awareness of sensation
 ____ areas - integrate diverse information to enable a purposeful action
 |  | Definition 
 
        | Three kinds of functional areas Motor areas -control voluntary motor functions
 Sensory areas - conscious awareness of sensation
 Association areas - integrate diverse information to enable a purposeful action
 |  | 
        |  | 
        
        | Term 
 
        | Motor Areas – Primary Motor Cortex Controls motor functions
 Primary motor cortex ( motor area) -___ lobe
 ____ cells – large neurons of primary motor cortex descend through brainstem and spinal cord
 Their axons signal motor neurons to control skilled movements
 |  | Definition 
 
        | Motor Areas – Primary Motor Cortex Controls motor functions
 Primary motor cortex (somatic motor area) -frontal lobe
 Pyramidal cells – large neurons of primary motor cortex descend through brainstem and spinal cord
 Their axons signal motor neurons to control skilled movements
 |  | 
        |  | 
        
        | Term 
 
        | ______ – pyramidal axons cross over to opposite side of the brain and spinal cord Right controls left side and vice and versa
 |  | Definition 
 
        | Contralateral – pyramidal axons cross over to opposite side of the brain and spinal cord (contra=opposite) Right controls left side and vice and versa
 |  | 
        |  | 
        
        | Term 
 
        | Specific pyramidal cells control specific areas of the body Face and hand muscles – controlled by __ pyramidal cells
 |  | Definition 
 
        | Specific pyramidal cells control specific areas of the body Face and hand muscles – controlled by many pyramidal cells
 |  | 
        |  | 
        
        | Term 
 
        | Motor homunculus – ___ of the motor cortex |  | Definition 
 
        | Motor homunculus – body map of the motor cortex |  | 
        |  | 
        
        | Term 
 
        | ______ – body is represented spatially in many parts of the CNS |  | Definition 
 
        | Somatotopy – body is represented spatially in many parts of the CNS |  | 
        |  | 
        
        | Term 
 
        | Motor Areas – Premotor Cortex Located ____ to the precentral gyrus
 Controls more ____ movements
 Receives processed sensory information
 Visual, auditory, and general somatic sensory
 Controls ____ actions dependent on sensory feedback
 Involved in the _____ of movements
 |  | Definition 
 
        | Motor Areas – Premotor Cortex Located anterior to the precentral gyrus
 Controls more complex movements
 Receives processed sensory information
 Visual, auditory, and general somatic sensory
 Controls voluntary actions dependent on sensory feedback
 Involved in the planning of movements
 |  | 
        |  | 
        
        | Term 
 
        | Motor Areas – Frontal Eye Field Lies_____to the premotor cortex
 Controls ____ movement of the eyes
 Especially when moving eyes to follow a moving target
 |  | Definition 
 
        | Motor Areas – Frontal Eye Field Lies anterior to the premotor cortex
 Controls voluntary movement of the eyes
 Especially when moving eyes to follow a moving target
 |  | 
        |  | 
        
        | Term 
 
        | Motor Areas – Broca’s Area Located in ___ cerebral hemisphere
 Manages ___ production
 Corresponding region in the right cerebral hemisphere
 Controls _____ overtones to spoken words
 |  | Definition 
 
        | Motor Areas – Broca’s Area Located in left cerebral hemisphere
 Manages speech production
 Corresponding region in the right cerebral hemisphere
 Controls emotional overtones to spoken words
 |  | 
        |  | 
        
        | Term 
 
        | Cortical areas (cortex) involved in conscious awareness of sensation Located in ___, __, and ___ lobes
 Distinct area for each of the major senses
 (6)
 |  | Definition 
 
        | Cortical areas (cortex) involved in conscious awareness of sensation Located in parietal, temporal, and occipital lobes
 Distinct area for each of the major senses
 Primary somatosensory
 Somatosensory association
 Vision
 Hearing
 Balance
 Taste
 |  | 
        |  | 
        
        | Term 
 
        | Sensory Areas – Primary Somatosensory  Cortex 
 Involved with conscious awareness of general somatic senses
 Sensory info picked up by sensory ____ in the periphery and relayed via spinal cord and brain stem
 
 Spatial discrimination – precisely locates a stimulus
 
 Projection is _____
 
 Damage to it, destroys ability to feel and localize touch, pressure, and vibrations on the skin. Ability to feel pain and temperature is lost
 |  | Definition 
 
        | Sensory Areas – Primary Somatosensory  Cortex 
 Involved with conscious awareness of general somatic senses
 Sensory info picked up by sensory receptors in the periphery and relayed via spinal cord and brain stem
 Spatial discrimination – precisely locates a stimulus
 Projection is contralateral
 Damage to it, destroys ability to feel and localize touch, pressure, and vibrations on the skin. Ability to feel pain and temperature is lost
 |  | 
        |  | 
        
        | Term 
 
        | Sensory Areas – Somatosensory  Association Area Lies _____ to the primary somatosensory cortex
 Integrates different sensory inputs
 Touch, pressure, and others
 Draws upon stored ____ of past sensory experiences
 |  | Definition 
 
        | Sensory Areas – Somatosensory  Association Area Lies posterior to the primary somatosensory cortex
 Integrates different sensory inputs
 Touch, pressure, and others
 Draws upon stored memories of past sensory experiences
 |  | 
        |  | 
        
        | Term 
 
        | Sensory Areas – Visual Areas Primary visual cortex
 On the ___ and ___ part of the occipital lobe
 Receives visual information that originates on the retina
 First of a series of areas that interprets visual input
 |  | Definition 
 
        | Sensory Areas – Visual Areas Primary visual cortex
 On the posterior and medial part of the occipital lobe
 Receives visual information that originates on the retina
 First of a series of areas that interprets visual input
 |  | 
        |  | 
        
        | Term 
 
        | Visual association area ____ the primary visual area
 Continues the processing of visual
 information
 Visual information proceeds in __ streams
 ____ stream –
 Responsible for recognizing objects, words, and faces
 ____ stream –
 Perceives spatial relationships
 ____ and ____ streams
 The “what” and “where” pathways
 |  | Definition 
 
        | Visual association area Surrounds the primary visual area
 Continues the processing of visual information
 Visual information proceeds in two streams
 Ventral stream –
 Responsible for recognizing objects, words, and faces
 Dorsal stream –
 Perceives spatial relationships
 Ventral and dorsal streams
 The “what” and “where” pathways
 |  | 
        |  | 
        
        | Term 
 
        | Sensory Areas – Auditory Areas Primary auditory cortex
 Function – conscious awareness of sound
 Location – ___ edge of the ____ lobe
 Auditory association area
 Lies ____ to the primary auditory cortex
 Permits evaluation of different sounds
 Involved in recognizing and understanding speech
 |  | Definition 
 
        | Sensory Areas – Auditory Areas Primary auditory cortex
 Function – conscious awareness of sound
 Location – superior edge of the temporal lobe
 Auditory association area
 Lies posterior to the primary auditory cortex
 Permits evaluation of different sounds
 Involved in recognizing and understanding speech
 |  | 
        |  | 
        
        | Term 
 
        | Sensory Areas – Gustatory Cortex Involved in the conscious awareness of ____ stimuli
 |  | Definition 
 
        | Sensory Areas – Gustatory Cortex Involved in the conscious awareness of taste stimuli
 |  | 
        |  | 
        
        | Term 
 
        | Sensory Areas – Vestibular Cortex ____. Sense of _____
 |  | Definition 
 
        | Sensory Areas – Vestibular Cortex Equilibrium. Sense of balance
 |  | 
        |  | 
        
        | Term 
 
        | Sensory Areas – Olfactory Cortex Lies on the ___ aspect of the cerebrum Located in a region called the ___ lobe Olfactory nerves transmit impulses to the olfactory cortex Provides conscious awareness of smells Part of the ____ – “nose brain” Includes – the ____ lobe, olfactory ___, and olfactory ____ Connects to the ___ system Explains why smells trigger emotions ____ cortex Involved with consciously identifying and recalling specific smells |  | Definition 
 
        | Sensory Areas – Olfactory Cortex Lies on the medial aspect of the cerebrum Located in a region called the piriform lobe Olfactory nerves transmit impulses to the olfactory cortex Provides conscious awareness of smells Part of the rhinencephalon – “nose brain” Includes – the piriform lobe, olfactory tract, and olfactory bulb Connects the brain to the limbic system Explains why smells trigger emotions Orbitofrontal cortex Involved with consciously identifying and recalling specific smells |  | 
        |  | 
        
        | Term 
 
        | Association Areas Include all cortical regions other than the ___ sensory and ___ areas
 Make associations between different types of sensory information
 Associate new sensory input with memories of past experiences
 New name for association areas – higher order _____ areas
 |  | Definition 
 
        | Association Areas Include all cortical regions other than the primary sensory and motor areas
 Make associations between different types of sensory information
 Associate new sensory input with memories of past experiences
 New name for association areas – higher order processing areas
 |  | 
        |  | 
        
        | Term 
 
        | Association Areas – Prefrontal Cortex Large region of the frontal lobe ____ to motor areas
 Performs cognitive functions
 All aspects of thinking and perceiving
 Remembering and recalling information
 Also related to mood
 Has close links to the ___ part of the forebrain
 Functional neuroimaging techniques
 Reveal functions of specific parts of the prefrontal cortex
 Anterior pole of frontal cortex
 Active in solving the ____ problems
 Functional areas located on the medial side of the frontal lobe
 Regions near the corpus callosum
 Involved in complex____ and ____ interactions
 Involved in “mentalization”
 |  | Definition 
 
        | Association Areas – Prefrontal Cortex Large region of the frontal lobe anterior to motor areas
 Performs cognitive functions
 All aspects of thinking and perceiving
 Remembering and recalling information
 Also related to mood
 Has close links to the limbic part of the forebrain
 Functional neuroimaging techniques
 Reveal functions of specific parts of the prefrontal cortex
 Anterior pole of frontal cortex
 Active in solving the most complex problems
 Functional areas located on the medial side of the frontal lobe
 Regions near the corpus callosum
 Involved in complex personal and social interactions
 Involved in “mentalization”
 |  | 
        |  | 
        
        | Term 
 
        | Association Areas – General Interpretation Area Function is currently under investigation
 Located at the interface of:
 The __, __, and ____ association areas
 Newer studies show most of this region is involved in the __ processing of ___ relationships
 |  | Definition 
 
        | Association Areas – General Interpretation Area Function is currently under investigation
 Located at the interface of:
 The visual, auditory, and somatosensory association areas
 Newer studies show most of this region is involved in the visual processing of spatial relationships
 |  | 
        |  | 
        
        | Term 
 
        | Association Areas – Language Area Surrounds the ____ sulcus in the __ cerebral hemisphere
 Five parts have been identified
 1.speech ____
 2.speech ______
 3.conceptual analysis of spoken words
 4.Coordination of ____ and ___ aspects of language
 5.Parts of the insula
 Initiation of ______
 Recognition of rhymes and sound sequences
 |  | Definition 
 
        | Association Areas – Language Area Surrounds the lateral sulcus in the left cerebral hemisphere
 Five parts have been identified
 speech production
 speech comprehension
 conceptual analysis of spoken words
 Coordination of auditory and visual aspects of language
 Parts of the insula
 Initiation of word articulation
 Recognition of rhymes and sound sequences
 |  | 
        |  | 
        
        | Term 
 
        | Association Areas – Insula Functions of its cortex – not well understood
 Some parts function in ____ and the sense of _____
 Other parts – visceral function
 _____ perception of:
 Upset stomach
 Full bladder
 Some aspects of the sense of _____
 |  | Definition 
 
        | Association Areas – Insula Functions of its cortex – not well understood
 Some parts function in language and the sense of balance
 Other parts – visceral function
 Conscious perception of:
 Upset stomach
 Full bladder
 Some aspects of the sense of smell
 |  | 
        |  | 
        
        | Term 
 
        | Lateralization of Cortical Functioning The two hemispheres control opposite sides of the body
 Hemispheres are specialized for different _____ functions
 Left cerebral hemisphere – more control over:____Language abilities, ____, and ___
 Right cerebral hemisphere – more involved with:
 ___-spatial skills
 Reading ____ expressions
 ____,____,____ and ____ skills
 |  | Definition 
 
        | Lateralization of Cortical Functioning The two hemispheres control opposite sides of the body
 Hemispheres are specialized for different cognitive functions
 Left cerebral hemisphere – more control over:
 Language abilities, math, and logic
 Right cerebral hemisphere – more involved with:
 Visual-spatial skills
 Reading facial expressions
 Intuition, emotion, artistic and musical skills
 |  | 
        |  | 
        
        | Term 
 
        | Cerebral White Matter Under gray matter
 Different areas of the cerebral cortex communicate:
 With _____
 With the ____ and ____
 Fibers are usually ___ and bundled into _____
 Tracts are classified based on where they run
 |  | Definition 
 
        | Cerebral White Matter Under gray matter
 Different areas of the cerebral cortex communicate:
 With each other
 With the brainstem and spinal cord
 Fibers are usually myelinated and bundled into tracts
 Tracts are classified based on where they run
 |  | 
        |  | 
        
        | Term 
 
        | Cerebral White Matter Commissures – composed of commissural ___ Allows communication between ____ Corpus callosum – the ___est commissure -____ to lateral ventricles  Association fibers Connect different parts of ____ Projection fibers – run ____ Descend from the cerebral cortex Ascend to the cortex from lower regions |  | Definition 
 
        | Cerebral White Matter Commissures – composed of commissural fibers Allows communication between cerebral hemispheres Corpus callosum – the largest commissure -superior to lateral ventricles Association fibers Connect different parts of the same hemisphere Projection fibers – run vertically Descend from the cerebral cortex Ascend to the cortex from lower regions |  | 
        |  | 
        
        | Term 
 
        | Deep Gray Matter of the Cerebrum Consists of:
 Basal ____ nuclei – associated with ___
 Basal ___ – involved in ___ control
 Claustrum – a ___ of unknown function
 Amygdala – located in ___ but is considered part of the of the ___ system
 |  | Definition 
 
        | Deep Gray Matter of the Cerebrum Consists of:
 Basal forebrain nuclei – associated with memory
 Basal ganglia – involved in motor control
 Claustrum – a nucleus of unknown function
 Amygdala – located in cerebrum but is considered part of the of the limbic system
 |  | 
        |  | 
        
        | Term 
 
        | Basal Forebrain Nuclei Functions are related to ___, ____, ___, and ____ control
 Degeneration is associated with Alzheimer
 |  | Definition 
 
        | Basal Forebrain Nuclei Functions are related to arousal, learning, memory, and motor control
 Degeneration is associated with Alzheimer
 |  | 
        |  | 
        
        | Term 
 
        | Basal Ganglia A group of ____ deep within the cerebral white matter
 Together, these nuclei are called the corpus _____
 Cooperate with the cerebral cortex in controlling ____
 Receive input from many cortical areas
 Evidence shows that they:
 Start, stop, and regulate intensity of _____ movements
 In some way estimate the passage of time
 |  | Definition 
 
        | Basal Ganglia A group of nuclei deep within the cerebral white matter
 Together, these nuclei are called the corpus striatum
 Cooperate with the cerebral cortex in controlling movements
 Receive input from many cortical areas
 Evidence shows that they:
 Start, stop, and regulate intensity of voluntary movements
 In some way estimate the passage of time
 |  | 
        |  | 
        
        | Term 
 
        | The Diencephalon Forms the center core of the ______
 Surrounded by the cerebral hemispheres
 Composed of three paired structures:
 ___, ____, and ____ (pineal gland)
 Border the ___ ventricle
 Primarily composed of __ matter
 |  | Definition 
 
        | The Diencephalon Forms the center core of the forebrain
 Surrounded by the cerebral hemispheres
 Composed of three paired structures:
 Thalamus, hypothalamus, and epithalamus (pineal gland)
 Border the third ventricle
 Primarily composed of gray matter
 |  | 
        |  | 
        
        | Term 
 
        | The Diencephalon – The Thalamus Makes up __ of the diencephalon
 Superolateral walls of the ___ ventricle
 Thalamus = “inner room”
 Contains approximately a dozen major ___
 Send axons to regions of the ___
 Nuclei act as relay stations for incoming ___ messages
 ____ impulses converge on the thalamus
 Is the “gateway” to the cerebral cortex
 Every part of the brain that communicates with the cerebral cortex must relay its signals through a nucleus of the thalamus
 Nuclei ___ and ___ or ___ signals
 Each nucleus of the thalamus sends its axons to a particular portion of the cerebral cortex
 Processes and relays information to the cerebral cortex
 |  | Definition 
 
        | The Diencephalon – The Thalamus Makes up 80% of the diencephalon
 Superolateral walls of the third ventricle
 Thalamus = “inner room”
 Contains approximately a dozen major nuclei
 Send axons to regions of the cerebral cortex
 Nuclei act as relay stations for incoming sensory messages
 Afferent impulses converge on the thalamus
 Is the “gateway” to the cerebral cortex
 Every part of the brain that communicates with the cerebral cortex must relay its signals through a nucleus of the thalamus
 Nuclei organize and amplify or tone down signals
 Each nucleus of the thalamus sends its axons to a particular portion of the cerebral cortex
 Processes and relays information to the cerebral cortex
 |  | 
        |  | 
        
        | Term 
 
        | The Diencephalon – The Hypothalamus Lies between the ___chiasm and the ___ bodies
 Pituitary gland projects ____ly
 Contains approximately a ___ nuclei
 Main ___ control center of the body
 ~ __ nuclei of ___ matter
 |  | Definition 
 
        | The Diencephalon – The Hypothalamus Lies between the optic chiasm and the mammillary bodies
 Pituitary gland projects inferiorly
 Contains approximately a dozen nuclei
 Main visceral control center of the body
 ~ 12 nuclei of gray matter
 |  | 
        |  | 
        
        | Term 
 
        | The Diencephalon – The Hypothalamus Functions include the following: Control of the ____ nervous system Peripheral ___ neurons that regulates contraction of ___ and ___ muscles and secretion of glands Regulation of ___ rate, ___ pressure, movement of ____, secretion of ___ and ___ glands Control of emotional responses -___ system Rage fear, sex drive, pleasure Regulation of body ___ Induce __ Regulation of ___ and ___ sensations Control of behavior Regulation of ____ cycles Control of the ____ system Control secretion of hormone by __ gland Formation of ____ |  | Definition 
 
        | The Diencephalon – The Hypothalamus Functions include the following: Control of the autonomic nervous system Peripheral motor neurons that regulates contraction of smooth and cardiac muscles and secretion of glands Regulation of heart rate, blood pressure, movement of digestive tube, secretion of sweat and salivary glands Control of emotional responses -limbic system Rage fear, sex drive, pleasure Regulation of body temperature -thermostat Induce fever, body cooling and heating Regulation of hunger and thirst sensations Control of behavior Regulation of sleep-wake cycles Control of the endocrine system Control secretion of hormone by pituitary gland Formation of memory |  | 
        |  | 
        
        | Term 
 
        | The Diencephalon – The Epithalamus Forms part of the “roof” of the ___ventricle
 Consists of a tiny group of nuclei
 Includes the ___ gland
 Secretes the hormone ____
 Under influence of the ____
 |  | Definition 
 
        | The Diencephalon – The Epithalamus Forms part of the “roof” of the third ventricle
 Consists of a tiny group of nuclei
 Includes the pineal gland (pineal body)
 Secretes the hormone melatonin
 Under influence of the hypothalamus
 |  | 
        |  | 
        
        | Term 
 
        | The Brain Stem Includes the ___, ___, and ____
 Make up ~2.5% total brain mass
 Several general functions
 Produces ___ behaviors necessary for survival
 Passageway for all fiber ___ running between the ___ and spinal cord
 Heavily involved with the innervation of the __ and ___
 __ of the 12 pairs of cranial nerves attach to it
 |  | Definition 
 
        | The Brain Stem Includes the midbrain, pons, and medulla oblongata
 Make up ~2.5% total brain mass
 Several general functions
 Produces automatic behaviors necessary for survival
 Passageway for all fiber tracts running between the cerebrum and spinal cord
 Heavily involved with the innervation of the face and head
 10 of the 12 pairs of cranial nerves attach to it
 |  | 
        |  | 
        
        | Term 
 
        | The Brain Stem – The Midbrain Involved with “_____” reaction
 Mediates response to ___ pain
 Lies between the ____ and the pons
 Central cavity – the cerebral ____
 |  | Definition 
 
        | The Brain Stem – The Midbrain Involved with “fight-and-flight” reaction
 Mediates response to visceral pain
 Lies between the diencephalon and the pons
 Central cavity – the cerebral aqueduct
 |  | 
        |  | 
        
        | Term 
 
        | The Brain Stem – The Pons Located between the midbrain and medulla oblongata
 Bridge between right and left halves of the ____
 Contains the nuclei of cranial nerves (3)
 |  | Definition 
 
        | The Brain Stem – The Pons Located between the midbrain and medulla oblongata
 Bridge between right and left halves of the cerebellum
 Contains the nuclei of cranial nerves V-enervates skin and face (trigeminal), VI-eye movement, and VII-muscels of the face
 |  | 
        |  | 
        
        | Term 
 
        | The Brain Stem – The Medulla Oblongata Most caudal level of the brain stem
 Continuous with the spinal cord
 Choroid plexus lies in the roof of the fourth ventricle
 Cranial nerves _____ attach to the medulla
 |  | Definition 
 
        | The Brain Stem – The Medulla Oblongata Most caudal level of the brain stem
 Continuous with the spinal cord
 Choroid plexus lies in the roof of the fourth ventricle
 Cranial nerves VIII–XII attach to the medulla
 |  | 
        |  | 
        
        | Term 
 
        | The Brain Stem – The Medulla Oblongata The core of the medulla contains:
 Much of the ___ formation
 Nuclei influence ____ functions
 ____ centers of the reticular formation include:
 (7)
 |  | Definition 
 
        | The Brain Stem – The Medulla Oblongata The core of the medulla contains:
 Much of the reticular formation
 Nuclei influence autonomic functions
 Visceral centers of the reticular formation include:
 Cardiac center
 Vasomotor center (blood pressure)
 The medullary respiratory center
 Centers for hiccupping, sneezing, swallowing, and coughing
 |  | 
        |  | 
        
        | Term 
 
        | The Cerebellum Located dorsal to the pons and medulla
 Smoothes and coordinates body ___ directed by other brain regions
 Helps maintain __ and ____
 |  | Definition 
 
        | The Cerebellum Located dorsal to the pons and medulla
 Smoothes and coordinates body movements directed by other brain regions
 Helps maintain posture and equilibrium
 |  | 
        |  | 
        
        | Term 
 
        | The Cerebellum Consists of two cerebellar hemispheres
 ~__% of total brain mass
 
 Surface folded into ridges called ___
 Separated by _____
 Hemispheres each subdivided into __ lobes
 |  | Definition 
 
        | The Cerebellum Consists of two cerebellar hemispheres
 ~11% of total brain mass
 
 Surface folded into ridges called folia
 Separated by fissures
 Hemispheres each subdivided into 3 lobes
 |  | 
        |  | 
        
        | Term 
 
        | The Cerebellum Composed of three regions
 Cortex – ___ matter
 Internal ___ matter
 Deep cerebellar __ – deeply situated ___ matter
 Cerebellum must receive information
 On equilibrium
 On current movements of limbs, neck, and trunk
 From the ____ cortex
 Damages to the cerebellum leads to coordination disorders, such as jerky movements
 People cannot touch with their finger their nose with closed eyes
 |  | Definition 
 
        | The Cerebellum Composed of three regions
 Cortex – gray matter
 Internal white matter
 Deep cerebellar nuclei – deeply situated gray matter
 Cerebellum must receive information
 On equilibrium
 On current movements of limbs, neck, and trunk
 From the cerebral cortex
 Damages to the cerebellum leads to coordination disorders, such as jerky movements
 People cannot touch with their finger their nose with closed eyes
 |  | 
        |  | 
        
        | Term 
 
        | The Cerebellum – Cerebellar Peduncles Thick tracts connecting the ___ to the ___
 Fibers to and from the cerebellum are ___lateral
 Run to and from ___ side of the body
 |  | Definition 
 
        | The Cerebellum – Cerebellar Peduncles Thick tracts connecting the cerebellum to the brain stem
 Fibers to and from the cerebellum are ipsilateral
 Run to and from the same side of the body
 |  | 
        |  | 
        
        | Term 
 
        | Functional Brain Systems Networks of neurons functioning together despite large distances within the brain
 The limbic system – spread widely in the _____
 The reticular formation – spans the ___
 |  | Definition 
 
        | Functional Brain Systems Networks of neurons functioning together despite large distances within the brain
 The limbic system – spread widely in the forebrain
 The reticular formation – spans the brain stem
 |  | 
        |  | 
        
        | Term 
 
        | Functional Brain Systems – The Limbic System Location
 _____ aspect of cerebral hemispheres
 Also within the _____
 The ____ and other tracts link the limbic system together
 Emotional brain
 Consolidates and retrieves ____
 Amygdala
 Contain nuclei for processing __ and than stimulating the appropriate sympathetic response to fear
 Allows people to recognize menacing facial expressions and
 detect the precise direction of the gaze of someone looking at them
 |  | Definition 
 
        | Functional Brain Systems – The Limbic System Location
 Medial aspect of cerebral hemispheres
 Also within the diencephalon
 The fornix and other tracts link the limbic system together
 Emotional brain
 Consolidates and retrieves memory
 Amygdala
 Contain nuclei for processing fear and than stimulating the appropriate sympathetic response to fear
 Allows people to recognize menacing facial expressions and
 detect the precise direction of the gaze of someone looking at them
 |  | 
        |  | 
        
        | Term 
 
        | Functional Brain Systems – The ____ System Encodes , consolidates and retrieves memories of facts and events
 |  | Definition 
 
        | Functional Brain Systems – The Limbic System Encodes , consolidates and retrieves memories of facts and events
 |  | 
        |  | 
        
        | Term 
 
        | Functional Brain Systems – The Reticular Formation Runs through the central core of the __, ___, and ___
 Widespread connections
 Ideal for arousal of the brain as a whole
 Reticular activating system (RAS)
 Maintains ___ and alertness
 Functions in ___ and arousal from __
 |  | Definition 
 
        | Functional Brain Systems – The Reticular Formation Runs through the central core of the medulla, pons, and midbrain
 Widespread connections
 Ideal for arousal of the brain as a whole
 Reticular activating system (RAS)
 Maintains consciousness and alertness
 Functions in sleep and arousal from sleep
 |  | 
        |  | 
        
        | Term 
 
        | Protection of the Brain The brain is protected from injury by
 (4)
 |  | Definition 
 
        | Protection of the Brain The brain is protected from injury by
 The skull
 Meninges
 Cerebrospinal fluid
 Blood-brain barrier
 |  | 
        |  | 
        
        | Term 
 
        | Protection of the Brain – Meninges 
 Three extensions of the dura mater separate parts of the brain: (3)
 |  | Definition 
 
        | Protection of the Brain – Meninges 
 Three extensions of the dura mater separate parts of the brain: the falx cerebri, falx cerebelli, and the tentorium cerebelli.
 |  | 
        |  | 
        
        | Term 
 
        | Protection of the Brain – Meninges Cover and protect the CNS
 Enclose and protect the ___ that supply the CNS
 Contain the ___ fluid
 External to internal the meninges are the
 (3)
 |  | Definition 
 
        | Protection of the Brain – Meninges Cover and protect the CNS
 Enclose and protect the vessels that supply the CNS
 Contain the cerebrospinal fluid
 External to internal the meninges are the
 Dura matter
 Arachnoid mater
 Pia mater
 |  | 
        |  | 
        
        | Term 
 
        | The Dura Mater Strongest of the meninges
 Composed of two layers
 ___ layer
 ___ layer
 Two layers are fused except to enclose the ___ sinuses
 |  | Definition 
 
        | The Dura Mater Strongest of the meninges
 Composed of two layers
 Periosteal layer
 Meningeal layer
 Two layers are fused except to enclose the dural sinuses
 |  | 
        |  | 
        
        | Term 
 
        | The Dura Mater Largest sinus – the superior ___sinus
 Dura mater extends inward to subdivide the cranial cavity to form flat partitions
 |  | Definition 
 
        | The Dura Mater Largest sinus – the superior sagittal sinus
 Dura mater extends inward to subdivide the cranial cavity to form flat partitions
 |  | 
        |  | 
        
        | Term 
 
        | The Arachnoid Mater Located beneath the dura mater
 ____ space
 Potential space between dura and arachnoid mater
 
 ____ space - deep to arachnoid matter
 
 Filled with CSF (cerebral spinal fluid)
 Contains the blood vessels that supply the brain
 Arachnoid ____ (movement)
 Allow CSF to pass into the dural blood sinuses
 |  | Definition 
 
        | The Arachnoid Mater Located beneath the dura mater
 Subdural space
 Potential space between dura and arachnoid mater
 Subarachnoid space
 Filled with CSF (cerebral spinal fluid)
 Contains the blood vessels that supply the brain
 Arachnoid villi
 Allow CSF to pass into the dural blood sinuses
 |  | 
        |  | 
        
        | Term 
 
        | The Pia Mater Delicate connective tissue
 Clings tightly to the ___ of the brain
 Follows all convolutions of the cortex
 |  | Definition 
 
        | The Pia Mater Delicate connective tissue
 Clings tightly to the surface of the brain
 Follows all convolutions of the cortex
 |  | 
        |  | 
        
        | Term 
 
        | Protection of the Brain – Cerebrospinal Fluid (CSF) Provides a liquid cushion for the brain and spinal cord
 The brain “floats” in CSF-reduces its weight by ~97%
 CSF nourishes the brain, removes ____ produce by neurons and hormones between different parts of the CNS
 100-160 ml is present at any time
 Formed in ____ in the brain ventricles
 Filtrate of the blood
 Resembles blood plasma but has more Na+ and Cl- and less ____
 Filtrate moves out of the capillaries, processed by the ____ cells, enters the ventricles, median and lateral apertures, subarachnoid space, arachnoid villi and into the blood of the superior sagittal sinus. Also into central canal of spinal cord
 |  | Definition 
 
        | Protection of the Brain – Cerebrospinal Fluid (CSF) Provides a liquid cushion for the brain and spinal cord
 The brain “floats” in CSF-reduces its weight by ~97%
 CSF nourishes the brain, removes wastes produce by neurons and hormones between different parts of the CNS
 100-160 ml is present at any time
 Formed in choroid plexuses in the brain ventricles
 Filtrate of the blood
 Resembles blood plasma but has more Na+ and Cl- and less protein
 Filtrate moves out of the capillaries, processed by the ependymal cells, enters the ventricles, median and lateral apertures, subarachnoid space, arachnoid villi and into the blood of the superior sagittal sinus. Also into central canal of spinal cord
 |  | 
        |  | 
        
        | Term 
 
        | Protection of the Brain – Blood-Brain Barrier Brain has a rich supply of capillaries
 Prevents most blood-borne toxins from entering the brain
 ____ capillaries - endothelium of capillary walls form ___ junctions
 Not an absolute barrier
 Nutrients such as __ pass through
 Allows alcohol, nicotine, and ___ through
 |  | Definition 
 
        | Protection of the Brain – Blood-Brain Barrier Brain has a rich supply of capillaries
 Prevents most blood-borne toxins from entering the brain
 Impermeable capillaries - endothelium of capillary walls form tight junctions
 Not an absolute barrier
 Nutrients such as oxygen pass through
 Allows alcohol, nicotine, and anesthetics through
 |  | 
        |  | 
        
        | Term 
 
        | The Spinal Cord Runs through the vertebral canal
 Extends from the ___ to the level of the vertebra __ or __
 Functions:
 Via spinal nerves, involved in ___ and ___ innervation of the entire body inferior to the head
 Two-ways conduction pathway for signals between body and brain
 Major center for _____
 Protected by __, ____, and ___
 Dura mater of the spinal cord is called the ____ – only one layer
 |  | Definition 
 
        | The Spinal Cord Runs through the vertebral canal
 Extends from the foramen magnum to the level of the vertebra L1 or L2
 Functions:
 Via spinal nerves, involved in sensory and motor innervation of the entire body inferior to the head
 Two-ways conduction pathway for signals between body and brain
 Major center for reflexes
 Protected by bone, meninges, and CSF
 Dura mater of the spinal cord is called the spinal dural sheath – only one layer
 |  | 
        |  | 
        
        | Term 
 
        | The Spinal Cord ___ and ___ enlargements Where nerves for upper and lower limbs arise ___ – collection of nerve roots that decend inferiorily past the end of the spinal cord. 31 pairs of spinal nerves (PNS) attach to the spinal cord through ventral and dorsal roots |  | Definition 
 
        | The Spinal Cord Cervical and lumbar enlargements Where nerves for upper and lower limbs arise Cauda equina – collection of nerve roots 31 pairs of spinal nerves (PNS) attach to the spinal cord through ventral and dorsal roots |  | 
        |  | 
        
        | Term 
 
        | Gray Matter of the Spinal Cord and Spinal Roots Shaped like the letter H
 Mixture of (4)
 ____ horns – contain cell bodies of motor neurons
 ____ horns – consist of interneurons
 Gray matter – divided according to ___ and ____ regions
 |  | Definition 
 
        | Gray Matter of the Spinal Cord and Spinal Roots Shaped like the letter H
 Mixture of cell bodies, short unmyelinated axons and dentrites and neuroglia
 Anterior horns – contain cell bodies of motor neurons
 Posterior horns – consist of interneurons
 Gray matter – divided according to somatic and visceral regions
 |  | 
        |  | 
        
        | Term 
 
        | White Matter of the Spinal Cord Composed of myelinated and unmyelinated axons
 Three types of fibers
 (3)
 |  | Definition 
 
        | White Matter of the Spinal Cord Composed of myelinated and unmyelinated axons
 Three types of fibers
 Ascending
 Descending
 Commissural
 |  | 
        |  | 
        
        | Term 
 
        | White Matter of the Spinal Cord Ascending
 Most of ascending fibers in the spinal cord carry ___ information from the ___ neurons of the body up to the ___
 Descending
 Most descending fibers carry ____ instructions from the ___ to the spinal cord, to stimulate __________
 Commissural
 Some fibers ______
 |  | Definition 
 
        | White Matter of the Spinal Cord Ascending
 Most of ascending fibers in the spinal cord carry sensory information from the sensory neurons of the body up to the brain
 Descending
 Most descending fibers carry motor instructions from the brain to the spinal cord, to stimulate contraction of the body muscles and gland secretions
 Commissural
 Some fibers cross from one side to the other
 |  | 
        |  | 
        
        | Term 
 
        | Sensory and Motor Pathways Most motor pathways:
 Consist of a chain of ___ neurons
 Exhibit ____ = Tracts arranged according to the body region they supply
 All pathways are ___
 One of each on each side of the body
 |  | Definition 
 
        | Sensory and Motor Pathways Most motor pathways:
 Consist of a chain of two or three neurons
 Exhibit somatotopy
 Tracts arranged according to the body region they supply
 All pathways are paired
 One of each on each side of the body
 |  | 
        |  | 
        
        | Term 
 
        | Ascending (Sensory) Pathways Conduct general somatic ___ impulses
 Chains of neurons
 Four main ascending pathways
 |  | Definition 
 
        | Ascending (Sensory) Pathways Conduct general somatic sensory impulses
 Chains of neurons
 Four main ascending pathways
 |  | 
        |  | 
        
        | Term 
 
        | Descending (Motor) Pathways Deliver ___ instructions from the brain to the spinal cord
 Divided into two groups
 |  | Definition 
 
        | Descending (Motor) Pathways Deliver motor instructions from the brain to the spinal cord
 Divided into two groups
 |  | 
        |  |