| Term 
 
        | What are the two circuits that the blood flows from the heart? |  | Definition 
 
        | 1. Pulmonary-> Right ventricle-> Lung (for gas exchange(Body has to always be unloading CO2))-> Left Atrium   2. Systemic-> Left ventricle-> Everywhere (Every cell w/ nutrients)-> Right Atrium   Systemic Circuit even nourishes lung and heart tissue |  | 
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        | Term 
 
        | Describe the base of the heart |  | Definition 
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        | Describe the Apex of the heart |  | Definition 
 
        | More narrow and Inferior Points toward the left |  | 
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        | Where does 2/3 of the heart lie? |  | Definition 
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        | What does the pericardium form? |  | Definition 
 
        | The pericardium forrms a sac around the heart |  | 
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        | What is the parietal pericardium? |  | Definition 
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        | What is the visceral pericardium? |  | Definition 
 
        | -Inner layer -In contact with the heart -Produces serous fluid |  | 
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        | What is the pericardial cavity? |  | Definition 
 
        | -Its a space located between parietal and visceral membrane. -It produces pericardial fluid between layers and this reduces friction |  | 
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        | Term 
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        | Inflammation of pericardium |  | 
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        | -Inner layer of the heart wall -Continuous with endothelium (inside of the heart that lines the vessel) of blood vessels |  | 
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        | -Middle layer of the heart wall -Cardiac muscle |  | 
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        | -The outer layer ofthe heart wall -Visceral pericardium |  | 
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        | (Blood supply to Myocardium?) 1. What does the Coronary Arteries do?    2. What do they branch off of?   3. Where does used blood collect and where does it empty into? |  | Definition 
 
        | 1. Supply heart tissue with blood 2. Branch off aorta immediately after aortic valve 3. Used blood collects in coronary sinus and empities into Right Atrium |  | 
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        | Term 
 
        | What is Myocardial Infarction? |  | Definition 
 
        | A heart attack which is an interruption of blood supply to heart tissue which is followed by nercrosis (death) of myocardium.   |  | 
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        | When does blood flow to the heart tissue peak? (Blood supply to myocardium step 1) |  | Definition 
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        | What does the cusps of aortic valve do during systole? (Blood supply to the myocardium step 2) |  | Definition 
 
        | Cusps of aortic valve cover Coronary artery opeing during systole |  | 
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        | What are compressed during systole? (Blood supply to myocardium step 3) |  | Definition 
 
        | Coronary arteries are compressed during systole |  | 
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        | What forces blood back into Coronary arteries? (Blood supply to myocardium step 4) |  | Definition 
 
        | Elastic recoil (the heart has to contract after it expands) of aorta forces blood back into the Coronary Arteries opendings during diastole. |  | 
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        | Does the heart spend more time in diastole or systole? |  | Definition 
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        | What is Angina Perctoris? |  | Definition 
 
        | Ischemia (Lack of blood flow (O2)) to myocardium |  | 
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        | What is the flow chart for Angina Pectoris? |  | Definition 
 
        | Anaerobic resp. --> Lactic acid --> pain/pressure feeling |  | 
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        | Term 
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        | The heart is Autorhythmic -This means no nervous system input is required. |  | 
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        | How do cardiocytes (cardiac muscle cells) look?   |  | Definition 
 
        | -Striated and branched -Joined w/ others by intercalated discs |  | 
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        | Term 
 | Definition 
 
        | -Are used to resist stress of contraction   They are like sutoskeleton that connect to other sytoskelton       |  | 
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        | What do Gap junctions allow? |  | Definition 
 
        | Allow ion flow between cells   (Like tubes that allow action potential) |  | 
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        | What are the two networks of the conduction system and what do they do? |  | Definition 
 
        | Atrial and Ventricular   -Each acts in near unison like single cell |  | 
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        | What is the Sinoatrial (SA) Node, where is it located, and what does it do first? (Step 1 of the Conduction System)  |  | Definition 
 
        | SA Node is a pacemaker -Its in the Right Atrium -Spontainious DEPOLARIZES FIRST |  | 
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        | What does SA not cause the atria to do? (Step 2 of conduction System) |  | Definition 
 
        | Causes both atria to depolarize and contract |  | 
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        | Where is the Atrioventricular (AV) node located and describe what happens with it.  (Step 3 of the conduction System)   Why is there a slight delay? |  | Definition 
 
        | -Located near Right AV valve -Depolarizes in response to artial depolarization.     -There is a slight delay prior to AV depolarization to allow ventricles to fill with blood. |  | 
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        | Where does AV send waves of depolarization? (Step 4 of the Conduction System)   Is the conduction fast or slow? |  | Definition 
 
        | AV sends wave of depolarization through RT and LT AV bundle branches to the apex of the ventricles. |  | 
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        | What do Purkinje fibers do? (Step 5 in the Conduction System)   What happens due to arrangement of cardiac muscle? |  | Definition 
 
        | Purkinji fivers carry the impulse from the end of the bundle braches superiorly to the cardiocytes of the ventricles.   Ventricular contraction from apex upward with a twisting motion do to arrangement of cardiac muscle. |  | 
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        | Why is an inferior to superior contraction useful? Consider where the blood must exit the chambers/ |  | Definition 
 
        | Because the blood has to exit through the aorta. |  | 
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        | What is a normal cardiac rhythm? |  | Definition 
 
        | SA node rhythm= sinus rhythm (70-80 bpm)-the number of times sa depolarizes- (60-100 are within normal range)   normal AV node 70-80 bpm as well because SA controls AV. |  | 
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        | ectopic focus (Cardiac Rhythm) |  | Definition 
 
        | Any other firing region (other than the SA node) |  | 
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        | What happens during Premature ventricular contraction (PVC)?   What kind of feeling does it give and why is it caused? (Cardiac Rhythm) |  | Definition 
 
        | Ventricle depolarizes before the SA node.  Gives an extrasystole (feeling of heart jumping/double beat/ flutter) cased by drugs/ stress/ lack of sleep... |  | 
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        | What is the most common ectopic focus?   When does it occur? |  | Definition 
 
        | AV node= nodal rhythm which = 40-50 bpm   Occurs when SA node is damaged. |  | 
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        | What is any other ectopic focus cause? What do you need to live? What can cause this? |  | Definition 
 
        | 20-40 bpm   Its not survivable   Need artificial pacemaker   Can be caused by heart block (failure of any part of the conduction system- Action potential stops premmature) |  | 
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        | When does action potential occur? (SA Node Physiology)   What is not stable?   What determines time to threshold and action potential? |  | Definition 
 
        | Action potential ovvurs when threshold membrane potential is reached.   RMP is not sbale but always creeps toward threshold as NA+ leaks through the cell membrane.   Rate of NA+ leak determines time to threshold and action potential. |  | 
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        | What are the stages of SA node physiology? |  | Definition 
 
        | 1. Slow Na= influx (leak) 2. Thresold reached 3. Ca++ amd Na+ channels opem (rapid depolarization=action potential) 4. K+ channels open (Ca++, Na+ close) repolarization 5. Repeat... |  | 
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        | What does a electrocardiogram (ECK or EKG) do? Where are electrodes placed to record ECG? |  | Definition 
 
        | Records heart electrical activity   Electrodes are placed on the wrist, ankles, and 6 places on the chest |  | 
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        | What are the three principal deflections of an ECG and what do they do? |  | Definition 
 
        | -P Wave= Atrial depolarization -QRS complex= Ventricular depolarization and Atrial repolarization -T Wave= Ventricular repolarization |  | 
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        | What happens if there are extra p waves? |  | Definition 
 
        | Heart block (not followed with ventricular wave) |  | 
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        | What happens if there and no P Waves? |  | Definition 
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        | What happens if there is and enlarged R? |  | Definition 
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        | they are very valuable for diagnosis of many heart problems. |  | 
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        | One complete contraction and relaxtion of all 4 heart chambers (high to low) |  | 
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        | To understand the cardiac cycle what do we need to consider? |  | Definition 
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        | What is the flood of fluid controled by? (in this case blood) |  | Definition 
 
        | Controlled by pressure and resistance |  | 
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        | What is blood pressure measured with? |  | Definition 
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        | Flow occurs from high to low pressure (down a pressure gradient) |  | 
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        | How do you get blood to go where you want it? |  | Definition 
 
        | The area must have lower pressure than where the blood currently in |  | 
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        | How does one achieve lowering pressure to get it where you want it to go? |  | Definition 
 
        | 1. Increase the blood pressure where it is 2. Decrease the pressure in the area you want it to go |  | 
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        | What kind of chamber is sytole and what does it do? |  | Definition 
 
        | Contracting chamber Inc. BP |  | 
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        | What kind of chamber is diastole and what does it do? |  | Definition 
 
        | Expanding (relaxing chamber) Decreases BP |  | 
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        | What are controlled by pressure in the heart chambers? |  | Definition 
 
        | Heart valve function and flow are controlled by pressure in the heart chamber |  | 
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        | What do systole and dystole normally refer to? What is an example? |  | Definition 
 
        | Systole and Diastole normally refer to ventricular systole and diastole.   (Systolic BP= arterial BP during ventricular systole) |  | 
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        | What happens during ventricular filling? What happens when the atria is 2/3rds full? What is EDV? What stage is this in the Cardiac Cycle? |  | Definition 
 
        | STAGE 1   During ventricular diastole,   AV valves OPEN  Passive flow of blood into ventricles from RT and LT ATRIA.   When 2/3rds full the atria DEPOLARIZES/ CONTRACT FILLING the other 1/3.   EDV= End diastolic volume (volume of ventricle after diastole = 130 ml/ventricle |  | 
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        | Why do both ventricles have to have equal amounts of ventricular filling? |  | Definition 
 
        | If they werent equal it would cause a back up (congestive heart failure) |  | 
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        | What is stage 2 of the Cardiac Cycle? What repolarizes and depolarize? What happens due to depolarization and what does this make? |  | Definition 
 
        | Stage two is Isovolumetric contraction   Atria repolarizes/ relaxes   Ventricles depolarize/ contract   Due to the depolarization there is an increas in pressure= AV valves forced shut from blood pressure against them   The shutting of the AV valves in Heart sound 1 |  | 
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        | What is stage 3 on the Cardiac cycle? What happens to ventricular pressure? What does the semi-lunar valves do? |  | Definition 
 
        | VENTRICULAR EJECTION   Ventricular pressure exceeds Aortic (80mm/hg) and P. Trunk (10mm/hg) pressuer against Semi-lunar valves.    Semi-lunar valves are forced open from blood pressure (120mm/hg from left ventricle and 25mm/hg from right) |  | 
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        | Stage three Ventricular ejection   What is the EDV= What does the SV= What is ESV? Using ESV, what is left in each ventricle after contraction? |  | Definition 
 
        | EDV= 130ml   SV (stroke volume)= 70ml  (the amount ejected)   EDV-SV= ESV (End systolic volume)  Basically what is left.   130-70= 60ml (left in each ventricle after contraction. |  | 
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        | What is stage 4? What happens to the ventricle? What have high pressure and why does it have high pressure? What does this high pressure do and what does it make? Why do AV valves open? |  | Definition 
 
        | ISOVOLUMETRIC RELAXTION   Ventricle repolarizes/ relaxes.   Aortic/ P. Trunk high pressure (Due to elastic recoil of artery walls)   The high pressure forces semilunar valves closed   The vavles closing makes heart sound 2   Av valves open because of low pressure in ventricles...repeat...   |  | 
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        | What is congestive heart failure? What causes it? What is the flow chart? |  | Definition 
 
        | Insufficient ventricular ejection from either ventricle   Cause blood back up in systemic or pulmonary circuit and subsequent edema.   Lt. Ventricle -> pulmonary edema Rt. Ventricle -> systemic edema |  | 
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