| Term 
 | Definition 
 
        | crescendo mid-late systolic click
 systolic
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | can hear when ascultating on back: |  | Definition 
 
        | - coarction of the aorta - pulmonic stenosis
 - aortic dissection
 |  | 
        |  | 
        
        | Term 
 
        | high blood pressure in UE, low blood pressure in LE: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | coarction of the aorta pts may have __ __ |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Aortic stenosis symptoms: |  | Definition 
 
        | - dyspnea - decreased exercise tolerance
 - fatigue
 - angina
 - syncope
 - sudden death
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - VSD - overriding of aorta over VSD
 - pumonic stenosis
 - RVH
 |  | 
        |  | 
        
        | Term 
 
        | results of not treating tetrology of fallot: |  | Definition 
 
        | pulmonary HTN> polycythemia arrhythmias> stroke |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | transposition of great arteries |  | 
        |  | 
        
        | Term 
 
        | With a junctional rhythm, the __ node is the pacemaker. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | accelerated junctional rhythm is greater than __ bpm. |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - Beta blockers - long term stroke prevention (Warfarin)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | Second degree heart block is block at the __ __. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | often don't treat PVCs. But if chronic PVCs can treat with ___. In an acute setting you can treat PVCs with _ and __. |  | Definition 
 
        | - Beta blockers - lidocaine and procanamide
 |  | 
        |  | 
        
        | Term 
 
        | tmt of complete heart block: |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - antiarrhythmics: vasopressin, amiodarone, procainamide, lidocaine - implant defib (ICD)
 |  | 
        |  | 
        
        | Term 
 
        | PVCs with R on T phenomenon can result in __ __. |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - defib - lidocaine
 - amiodarone
 - procainamide
 - beta blockers
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | results after early PVC with a pause: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Erythromycin and Seldane may cause: |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | magnesium and cardioversion |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - amiodarone - lidocaine
 - procainamide
 - beta blockers
 |  | 
        |  | 
        
        | Term 
 
        | Sodium channel blockers __ __. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Beta blockers and calcium channel blockers __ __ __. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Potassium channel blockers prolong __ __. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | a fib tmt focus is on __. use __ __ and __ . |  | Definition 
 
        | - rate - beta blockers
 - non-dihydropyridine calcium channel blockers
 |  | 
        |  | 
        
        | Term 
 
        | Supraventricular tachycardia tmt: |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | Long QT syndrome can lead to : |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | disease of the ions channel leading to prolonged action potentials, these pts also have increased sympathetic activity in the heart: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | metabolic causes of LQTS: |  | Definition 
 
        | - hypokalemia - hypomagnesia
 - hypocalcemia
 - hypothyroidism
 - anorexia
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - antiarryhtmics- sotalol, amiodarone - macrolides
 - fluroquinolones
 - Psychotropic: Haldol, TCAs, Thloridazine
 - SSRIs: Risperidone Methadone, Droperidol, protease inhibitors
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - Beta blockers - Defibrillator
 |  | 
        |  | 
        
        | Term 
 
        | Genetic disease with EKG changes but structurally normal hearts: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Brugada syndrome is more common at __ |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - RBBB - persistent ST elevation of cove-like morphology
 - T wave inversion in V1, V2, V3
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | coved ST elevation of greater than 2 mm with negative T wave |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | saddleback ST elevated of greater than or equal to 2 mm with ST troughs greater than or eequal to 1 mm |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | coved/saddle ST elveation greater than or equal to 2 mm, with ST trough less than 1 mm |  | 
        |  | 
        
        | Term 
 
        | mutation of Brugada syndrome: |  | Definition 
 
        | SCN5A sodium channel mutation- dominant |  | 
        |  | 
        
        | Term 
 
        | LQTS is more common in men/women? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Most lethal of the cardiac channelopathies: |  | Definition 
 
        | Catecholamine Polymorphic Ventricular Tachycardia (CPVT) |  | 
        |  | 
        
        | Term 
 
        | exertional palpitations and syncope: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Genetic mutations with CPVT: |  | Definition 
 
        | - Ryanodine (RYR2)- most common - Calsequestrin (CASQ2)- recessive
 |  | 
        |  | 
        
        | Term 
 
        | these pts have a NORMAL EKG, but are at great risk for sudden cardiac death: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Brugada pts have a structurally normal heart, but an abnormal EKG. CPVT have normal EKGs. |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - exercise stress test> bidirectional VT with a beta to beat 180 degree rotation of QRS |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | Aschoff body with biopsy indicates: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Rheumatic fever is an __ __ disorder of __ __, __, __, and __ __. |  | Definition 
 
        | - inflammatory autoimmune - connective tissue
 - heart
 - joints
 - blood vessels
 |  | 
        |  | 
        
        | Term 
 
        | Dx of Rheumatic fever requires: |  | Definition 
 
        | - 1 major Jone's criteria - 2 minor Jone's criteria
 - evidence of recent strep infection
 |  | 
        |  | 
        
        | Term 
 
        | Jones major criteria for Rheumatic Fever: |  | Definition 
 
        | Come Meet Corinne Soon Erika. - Carditis
 - Migratory polyarthritis
 - Chorea
 - Subcutaneous nodules- painless
 - Erythema marginatum
 |  | 
        |  | 
        
        | Term 
 
        | Jones minor criteria for rheumatic fever: |  | Definition 
 
        | Can't Find A Lab And Purse. - Clinical
 - Fever
 - Athralgia
 - Labs
 - Acute phase reactants increased (ESR, CRP)
 - Prolonged PR interval
 |  | 
        |  | 
        
        | Term 
 
        | Evidence of recent GAS infection: |  | Definition 
 
        | - positive throat culture - rapid antigen detection
 - increased strep antibody test
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | signs of ascending aortic aneurysm: |  | Definition 
 
        | - distend neck veins (vena cava obstruction) - aortic regurg (displacement of aortic valve)
 - hoarseness (left recurrent laryngeal nerve)
 
 DAH
 |  | 
        |  | 
        
        | Term 
 
        | S/S of descending thoracic aortic aneurysm: |  | Definition 
 
        | - wheezing, stridor, cough (tracheal compression) - dysphagia (esophageal compression)
 |  | 
        |  | 
        
        | Term 
 
        | S/S of acute arterial occlusion: |  | Definition 
 
        | - pain - pallor
 - pulselessness
 - polar sensation (cold)
 - paresthesia
 |  | 
        |  | 
        
        | Term 
 
        | Dx of acute arterial occlusion: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Chronic Arterial Occlusion is aka __ __ __. |  | Definition 
 
        | Peripheral Arterial Disease |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - smoking - HTN
 - dyslipidemia
 - diabetes
 - fhx atherosclerosis
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | ABI ratio (ankle:arm systolic bp ratio) 
 less than 0.9 i s abnormal
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - intermittent claudication - thinning skin/hair on extermities
 - uclers on toes/heals may occur
 - pallor
 - cyanosis
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - exercise - antiplatelets: ASA, clopidogrel
 - Cilostazol (not for CHF)
 - Pentoxifyllin
 |  | 
        |  | 
        
        | Term 
 
        | Tmt of giant cell arteritis: |  | Definition 
 
        | - corticosteroids: prednisone 40-60 mg |  | 
        |  | 
        
        | Term 
 
        | Dx criteria for Temporal Arteritis, must have 3 of the following 5: |  | Definition 
 
        | So Next Time Please Stay - Symptoms in pt older than 50 yrs
 - New onset HA/localized pain
 - Temporal artery tenderness to palpation
 - decreased Pulsations
 - Sed rate great than 50
 |  | 
        |  | 
        
        | Term 
 
        | pt has dull achy legs that feel heavy, worse in evening and after exercise, ankle sweeling, skin is ithciny and thin: |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - compression stockings - sclerotherapy
 - surgical vein ligation and removal
 |  | 
        |  | 
        
        | Term 
 
        | To dx Infectious Endocarditis must have: |  | Definition 
 
        | - 2 major dx criteria OR - 1 major + 3 minor criteria OR
 - 5 minor criteria
 |  | 
        |  | 
        
        | Term 
 
        | Duke Major Dx criteria for Infectious Endocarditis: |  | Definition 
 
        | 1. 2 separate positive blood cultures 2. Positive echo findings
 3. New Valvular Regurgitation
 |  | 
        |  | 
        
        | Term 
 
        | Duke Minor Criteria for Infectious Endocarditis: |  | Definition 
 
        | 1) Predisposition (hx of IV drugs/CHD) 2) Fever with temp greater than 38 C
 3) Vascular phenomenon
 4) Immunologic phenomenon
 5) Positive blood culture w/o meeting above criteria or serologic evidence of active infxn
 |  | 
        |  | 
        
        | Term 
 
        | Infective Endocarditis tmt; |  | Definition 
 
        | Penicillin G for 4 weeks 
 OR
 
 Ceftriaxone + Gentamycin for 2 weeks
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | neoplastic disease of the heart |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | hypotension muffled heart sounds
 JVD
 |  | 
        |  | 
        
        | Term 
 
        | Becks triad and pulsus paradoxus are seen with __ __. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | pulsus paradoxus defined: |  | Definition 
 
        | fall of bp greater than or equal to 10 mmHg with inspiration |  | 
        |  | 
        
        | Term 
 
        | EKG findings of cardiac tamponade: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | drugs that may cause pericardial effusion: |  | Definition 
 
        | - minoxidil - hydralazine
 - phenytoin
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | increased JVP during inspiration |  | 
        |  | 
        
        | Term 
 
        | Pericardial effusion tmt: |  | Definition 
 
        | - NSAIDs - colchicine
 - steroids (may cause relapse)
 
 acute: pericardiocentesis
 chronic: pericardial window
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | diffuse st elevation t wave inversions
 |  | 
        |  | 
        
        | Term 
 
        | diffuse ST elevations, pain is worse when laying down, better sitting up: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Pericarditis usually has a __ cause. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | PRECORDIAL/SUBSTERNAL CHEST SHARP STABBING CHEST PAIN THAT RADIATES TO THE BACK, NECK, LEFT SHOULD, ARM. INSPIRATION AGGRAVATES THE PAIN: |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - treat cause and hemodynamics changes - inflammation: NSAIDs, corticosteroids, Abx
 |  | 
        |  | 
        
        | Term 
 
        | constrictive pericarditis: |  | Definition 
 
        | fibrous changes of pericaridum : caused by radiation, infections, surgery |  | 
        |  | 
        
        | Term 
 
        | constrictive pericarditis has a __ onset. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | aortic stenosis causes a __ S2. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Aortic stensois has a __ pulse pressure. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Aortic regurgitation has Quinckes pulses which alternate __ and __ with __ and __ __. |  | Definition 
 
        | - blanching and flushing with diastole |  | 
        |  | 
        
        | Term 
 
        | Tmt of aortic regurgitation: |  | Definition 
 
        | no tmt if not bad hydralazine
 nifedipine
 ACE-I
 
 (decrease resistance to decrease aortic regurg)
 |  | 
        |  | 
        
        | Term 
 
        | Mitral stenosis symptoms: |  | Definition 
 
        | - exertional dyspnea - paroxysmal nocturnal dyspnea
 - orthopnea
 - LOUD S1 OPENING SNAP
 - LEFT ATRIAL ENLARGEMENT
 |  | 
        |  | 
        
        | Term 
 
        | Mitral stenosis is more common in : |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Mitral stenosis causes enlargement of the __ __, while mitral regurgitation causes enlargment of the __ __. |  | Definition 
 
        | - left atrium - left ventricle
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - hydralazine - nifedipine
 - nitroprusside
 |  | 
        |  | 
        
        | Term 
 
        | Tricuspid stenosis has a prominent __ wave on jugular venous inspection. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Tricuspid regurgitation has a prominent __ wave on jugular venous inspection. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | tmt of tricuspid regurgitation: |  | Definition 
 
        | - diuretics to prevent pulmonary HTN |  | 
        |  | 
        
        | Term 
 
        | 2nd most common congenital heart disease: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Pulmonary HTN results in __ __ called a __ ___ __. |  | Definition 
 
        | - pulmonic regurg - Graham steele murmur
 |  | 
        |  | 
        
        | Term 
 
        | Tmt of pulmonic regurg and tricuspid regurg: |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - beta blockers - CCB
 - anti-arrythmics
 - avoid dehydration
 - septal ablation
 |  | 
        |  | 
        
        | Term 
 
        | with aortic/mitral regurgitaion treatment focus is on decreasing __ __ _ via __, __, and/or __. |  | Definition 
 
        | - systemic vascular resistance - hydralazine
 - dihyrdro CCBs (nifedipine_
 - ACE-I
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MAP= diastolic pressure + (1/3)(pulse pressure) 
 MAP= 1/3 (systolic) + (2/3) (diastolic)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | systolic pressure- diastolic pressure = pulse pressure |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | Ejection fraction formula: |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | highest ankle systolic bp/ highest brachial systolic bp |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | formula for sodium needed: |  | Definition 
 
        | mEq sodium needed = (140-serum sodium)x TBW |  | 
        |  | 
        
        | Term 
 
        | Fractional excretion of sodium formula: |  | Definition 
 
        | FNa= (Urine sodium x Serum Cr)/(Serum sodium x Urine Cr) 
 less than 1= low fluid, normal kidneys
 greater than 1= impaired kidney function
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - normal kidneys, low fluid |  | 
        |  | 
        
        | Term 
 
        | FNa greater than one means; |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | formula for Systemic Vascular Resistance: |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | IV gamma globulin 1-2 g/kg dose given over 12 hours 
 NO LIVE VIRUS VACCINES FOR NEXT 11 MONTHS
 
 80-100mg/kg/day of Aspirin divided into 4-6 doses until fever subsides
 
 Reduce ASA to 2-10mg/kg/day after fever subsides
 
 May need coumadin if pt has large coronary artery aneurysms
 |  | 
        |  | 
        
        | Term 
 
        | If you use coumadin in pts with Kawasakis, what is there target INR? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | symptoms of lymphatic filarisis: |  | Definition 
 
        | episoditc attacks of lymphangitis/adenitis, fever, epididymitis, elephantitis, and lymphedema |  | 
        |  | 
        
        | Term 
 
        | asymptomatic pts with lymphatic filarisis still have hidden damage to the __ __ and __. |  | Definition 
 
        | - lymphatic system and kidneys |  | 
        |  | 
        
        | Term 
 
        | Acute lymphatic filarisis symptoms: |  | Definition 
 
        | - filarial fever: pain/inflammation of lymph nodes/duct, accompanied by fever, nausea, vomiting |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | elephantitis and possibly hydrocele in males and enlarged breasts in females |  | 
        |  | 
        
        | Term 
 
        | dx of lymphatic filarisis: |  | Definition 
 
        | - hard to isolate microfilae b/c they're nocturna - CARD TEST- FINGER STICK TEST THAT DETECTS PARASITE ANTIGEN, does not require lab equipement
 |  | 
        |  | 
        
        | Term 
 
        | Tmt of lymphatic filarisis: |  | Definition 
 
        | - Diethylcarbamazine (DEC): reduces microfillae concenetrations, kills adult worms - Albendazole- kills adult worms
 - Ivermectin-kills microfillae made my adult worms
 - Doxycycline
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - Diabetes - AAA
 - PAD
 - symptomatic carotid artery disease
 - multiple risk factors leading to a 10 year CHD risk of greater than 20%
 |  | 
        |  | 
        
        | Term 
 
        | 0-1 CHD risk factor LDL goal; |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | 2+ CHD risk factors, LDL goal: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | CHD and CHD risk equivalents LDL goal : |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | greater than or equal to 60 |  | 
        |  | 
        
        | Term 
 
        | Total cholesterol should be less than __, between __ and __ is borderline high, and greater than or equal to __ is high. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | causes of secondary dyslipidemia: |  | Definition 
 
        | - Diabetes - Hypothyroidism
 - Obstructive liver disease
 - Chronic renal failure
 - Drugs that raise LDL and lower HDL (progestins, anabolic steroids, corticosteroids)
 |  | 
        |  | 
        
        | Term 
 
        | 5 major risk factors when determing LDL goal: |  | Definition 
 
        | - Hypertension - Smoking
 - Low HDL
 - First degree relative with early CHD (less than 55 in males or less than 65 in females)
 - Age (45 and over for males, 55 and over for females)
 |  | 
        |  | 
        
        | Term 
 
        | When to initial LDL lowering drugs in pts with CHD or CHD risk equivalents: |  | Definition 
 
        | LDL greater than or equal to 130 
 (remember their goal is less than 100)
 |  | 
        |  | 
        
        | Term 
 
        | In patients with 2+ CHD risk factors, their goal LDL is less than __. Initiate drug therapy at __ if their 10 year risk factor is 10-20% or at __ if their 10 year risk factor is less than 105. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | With pts who have 0-1 CHD risk factor initiate drug therapy if their LDL gets to __ or higher. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | General features of metabolic syndrome: |  | Definition 
 
        | - abdominal obesity - atherogenic dislipidemia
 - HTN
 - insulin resistance
 - prothrombic state
 - proinflammatory state
 |  | 
        |  | 
        
        | Term 
 
        | on a TLC diet, saturated fat should be less than __ of your total calories and dietary cholesterol should be less than ___/day. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | LDL lowering therapeutic options: |  | Definition 
 
        | - Plant stanold/sterols (2g/day) - Viscous soluble fiber (10-25 g/day)
 |  | 
        |  | 
        
        | Term 
 
        | saturated fat should be less than 7% daily calories, polyunsaturated fat less than 10%, and monounsaturated fat less than 20% |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Metabolic Syndrome synonyms: |  | Definition 
 
        | - insulin resistance syndrome - metabolic syndrome x
 - Dysmetabolic syndrome
 - Multiple Metabolic syndrome
 |  | 
        |  |