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| The 5 functions of the skeletal system |
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| Mobility, Production of blood cells, Protection of vital organs, Structure, and Storage of minerals (MoPPSS) |
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| Stem cells from which ALL connective tissue descends |
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| cartilage low in fiber content, found in tip of nose and costal cartilage of (true) ribs |
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| high in collagen; characterized by large red bands |
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| cartilage high in elastin; characterized by thin bands; found in ears |
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| Connective tissue that is bone to muscle vs. bone to bone |
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| cells which form the matrix of hyaline cartilage |
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| cells found in hyaline cartilage which maintain the matrix; housed in lacunae |
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| made up of collagen fibers (though not to the extent of fibrocartilage) and proteoglycans for strength and resiliency respectively |
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Two layers of connective tissue surrounding cartilage: Inner--less fibers, contains chondroblasts Outer--vasculated cells, provide nutrients |
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| degree of vascularization of cartilage |
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Definition
| 0. All cartilage is AVASCULAR. |
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| covers bones at joints; no perichondrium |
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| new chondrocytes/matrix at periphery |
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| chondrocytes divide, and add more matrix b/t cells |
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| CaPO4 crystals, makes up the inorganic portion of the bone matrix (stiffness) |
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| collagen fibers and proteoglycans (durability) |
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| 3 types of bone cells and purposes |
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Definition
osteoblasts: precursor, forms matrix through osteogenesis/ossification osteocytes: maintenence osteoclasts: remolding, maintains Ca2+ concentration in BLOOD; multinucleated |
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randomly oriented collagen fibers found in newly formed bone (fetal, fracture repair) |
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mature bone (sheets), formed in concentric circles around central/haversian canals remodelled from woven |
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| "spongy" bone: contains trabeculae, spaces filled w/marrow |
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| dense bone; built through endochondral ossification |
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| osteogenesis/ossification |
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collagen produced by ER of osteoblasts, released by exocytosis via golgi; hydroxyapatite precursors stored in vesicles and released via exocytosis Osteoblasts communicate through gap junctions |
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| space occupied by osteocyte |
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| spaces occupied by osteocyte cell processes |
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| ruffled border on osteoclast: releases H+'s and enzymes to break down bone |
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| osteoclast precursors formed from red marrow stem cells |
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| Osteochondral progenitor cells |
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| precursors of osteoblasts and chondroblasts |
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| interconnecting rods/plates of bone; covered w/ endosteum; oriented along stress lines |
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| parallel to long axis of bone, contain vessels |
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| perforating/volkmann's canal |
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| perpendicular to long axis of bone, vessels |
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layers of bone that can be any of the following: concentric--layered in circles around a central canal interstitial--filling spaces between osteons circumferential--layered around edge of bone, just deeper than periosteum |
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| a central canal and it's surrounding lamellae, osteocytes, and their contents |
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long (longer than wide) short (nearly cuboid) flat (ex: ribs, sternum, skull, scapulae) irregular (ex: vertebrae, facial) |
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growth plate in epiphysis, hyaline cartilage present until growth stops, then ossifies into epiphyseal line |
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| cavity central in bone; red marrow becomes yellow marrow in limbs and skull(except epiphyses in long bones), all others stay red |
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| double layer: outer is highly fibrous (tendons become continuous herewith), inner is a layer of 'blasts, 'clasts, and progenitors; if outer is lost, important cells are exposed |
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| penetrate from outer periosteum into bone, strengthens tendons |
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| similar to periosteum, more cellular; lines all inner spaces of bone |
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