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400
Veterinary Medicine
Graduate
05/12/2012

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Term
Pectoral abscesses in horses ("Pigeon Fever") are a result of infection with which organism?
Definition
Corynebacterium pseudotuberculosis
Term
What are two common differential diagnoses for multiple homogenous gray-white nodules in the kidney of a cat?
Definition
Lymphosarcoma, Feline Infectious Peritonitis (FIP)
Term
Name 3 cutaneous manifestations of hepatic failure
Definition
icterus, necrolytic dermatitis, photosensitization, ecchymoses/bruising, poor wound healing
Term
What is the most common type of oral neoplasm in cats?
Definition
SCC
Term
A mare presents with a history of stallion-like behavior and a large ovarian mass, which on cut surface is cystic. What is the likely diagnosis?
Definition
Granulosa Cell Tumor
Term
The the two most common pathogenic bacteria associated with canine keratomalacia?
Definition
Strep and Staph spp.
Term
Renal conjugation of bilirubin with urinary excretion is seen in which domestic species?
Definition
Dogs
Term
Intradermal skin testing for mycobacterium bovis is an example of what type of hypersensitivity reaction?
Definition
Type IV
Term
since striated muscle cells do not replicate, physiologic enlargement is due to ___ of myocytes.
Definition
Hypertrophy
Term
How do dogs typically become infected by Neorickettsia helminothoeca?
Definition
Ingestion of raw fish parasitized by Nanophyteus salmincola (trematode) carrying nanophyteus helminthoeca
Term
Necrosis in the CNS is typically of which pathological type?
Definition
Liquefactive
Term
Which gram-negative RBC parasite causes anemia in cats?
Definition
Mycoplasma haemofelis (Hemobartonella felis)
Term
Which organism is the most common cause of fungal nasal infections in dogs?
Definition
Aspergillus fumigatus
Term
Leishmania spp. are intracellular parasites of which cell type, primarily?
Definition
macrophages
Term
Upon ligation of a PDA, the aortic and carotid baroreceptors sense a rise in blood pressure, triggering the Branham reflex. What is the response?
Definition
Decrease in heart rate
Term
What is the etiologic agent associated with equine sarcoids?
Definition
Bovine papillomavirus 1 & 2
Term
At rest, skin, erythrocytes, brain, skeletal muscle, and intestine all produce lactate. Which of these are the major producers of lactate during systemic tissue hypoxia?
Definition
Skeletal muscle & intestine
Term
What is the mechanism of edema caused by inflammation?
Definition
Endothelial damage leading to increased vascular permeability
Term
In myocaridal infarction, the primary type of healing involves which type of cell?
Definition
fibroblast
Term
Right heart failure affects which zone of the hepatic lobule?
Definition
centrilobular (zone 3)
Term
What is the causative agent of infectious canine hepatitis?
Definition
canine adenovirus 1
Term
Foxglove, Lily of the valley, and Oleander plants all contain the same toxic agent. What is it?
Definition
Digitalis glycosides causing cardiac arrhythmias, anorexia, lethargy, and nausea
Term
What are the average RBC lifespans in circulation for the cow and the horse?
Definition
Cow: 160 d; Horse: 145 d
Term
What does a V/Q mismatch of infinity mean? In what clinical situation may this occur?
Definition
Alveoli are receiving ventillation but have no blood flow (V/Q=1/0), as many occur with a pulmonary embolus
Term
What effect does aldosterone have on the collecting duct of the kidney?
Definition
enhances resorption of sodium & water
Term
Where is renin produced?
Definition
juxtaglomerular cells of the kidney
Term
What is the minimum number of weeks of oral antibiotic administration typically recommended for treatment of superficial pyodermas?
Definition
3-4 weeks
Term
Which hormone is most important in fine regulation of blood calcium levels, with highest levels being elicited when blood calcium levels are low?
Definition
PTH
Term
What is the potential concern with combining Tramadol with a pure mu-receptor agonist opioid (e.g. morphine, hydromorphone)?
Definition
Compounding CNS and respiratory depression
Term
Do T lymphocytes function primarily in cell-mediated or humoral (antibody-mediated) immunity?
Definition
cell-mediated (CMI)
Term
Which porcine virus causes disease that is characterized by SMEDI (stillbirth, mummification, early embryonic death, and infertility)?
Definition
porcine parvovirus (PPV)
Term
What is the etiologic agent for bacillary hemoglobinuria (icterohemoglobinura)?
Definition
Clostridium hemolyticum/C. novyi type D ("Red water")
Term
This trematode causes severe disease in sheep but often mild clinical disease in cattle and cervids?
Definition
Facioloides magna
Term
Which bacterial etiologic agent is responsible for septic vasculitis with secondary thrombosis in the CNS of cattle?
Definition
Histophilus somni
Term
What are the three classical histologic findings in the liver resulting from pyrrolizidine alkaloid toxicosis in herbivores?
Definition
1) fibrosis 2) bile duct proliferation 3) megalocytosis
Term
What is the effect of hypomagnesemia on the cell membrane threshold potential?
Definition
decreased threshold potential (increased cellular excitability)
Term
Rhodococcus equi, an obligate intracellular bacterium infects which immune cell?
Definition
macrophage
Term
How does severe hypophosphatemia cause anemia?
Definition
Hemolysis due to cell membrane deformity (also decreased ATP availability)
Term
One which ionic process are oxytocin-induced uterine contractions dependent?
Definition
Adequate influx of extracellular calcium
Term
What is the most common cause of fungal infection of the nail in dogs? cats?
Definition
Dogs: Trichophyton mentagrophytes; Cats: Microsporum canis
Term
Which structure in birds is the location of B cell differentiation?
Definition
Bursa of fabricius
Term
Name 2 classes of antibiotics that act by inhibiting cell wall synthesis?
Definition
Penicillins & Cephalosporins
Term
Newcastle disease is caused by a virus of which family?
Definition
Paramyxoviridae
Term
Bromethalin rodenticide intoxication affects which body system?
Definition
CNS
Term
Which component of a blood pressure measurement (systolic, diastolic, or mean) is the best determinant of organ perfusion?
Definition
Mean Arterial Pressure (MAP)
Term
Name 3 drugs that reduce circulating thyroid hormone levels?
Definition
sulfonamides, CS, phenobarbitol, clomipramine, NSAIDS, methimazole
Term
What is the intermediate host for the tapeworm Dipylidium caninum?
Definition
The flea
Term
___ is the major intracellular cation and ___ is the major extracellular cation?
Definition
K+, Na+
Term
Which 2 domestic animal species are most susceptible to infection with Bacillus anthracis?
Definition
Cattle & Sheep
Term
Canine localized demodicosis most often produces lesions localized to these areas of the body?
Definition
Face & Forelimbs
Term
Cephalexin is a member of which class of antibiotics?
Definition
First generation Cephalosporin
Term
What is the maximum rate of decrease in plasma sodium levels during the treatment of chronic (>24 h) severe hypernatremia
Definition
8-12 mEq/L/d (or 0.5 mEq/l/h); a more rapid rate of correction risks cerebral edema
Term
Rocky Mountain Spotted Fever is a tick-borne zoonosis caused by this gram negative obligate intracellular parasite?
Definition
Rickettsia rickettsii
Term
Which organ system in which livestock species is the reservoir for Brachyspira hyodysenteriae?
Definition
Porcine gastrointestinal tract
Term
Deficient production or lack of response to this hormone results in diabetes insipidus?
Definition
ADH (vasopressin)
Term
Zinc-responsive dermatosis is a zinc deficiency-induced disorder of keratinization common in this type of dog breed?
Definition
Northern (Siberian husky, Samoyed, Alaskan malamute)
Term
The Cushing reflex/Cushing response is activated with severe increases in intracranial pressure. What is the expected change in arterial blood pressure that occurs as a result of the Cushing reflex?
Definition
Systemic arterial hypertension
Term
Which phase of estrus in dogs and cats is predominantly characterized by high circulating levels of progesterone?
Definition
Diestrus
Term
What kind of virus are the parvoviruses?
Definition
Single stranded, negative-sense DNA viruses
Term
What is the most common clinical manifestation of brucellosis in males?
Definition
Orchitits and epididymitis
Term
Brucellosis is a disease of worldwide importance and affects a number of animal species. What is the most common clinical manifestation in females?
Definition
Abortion
Term
Necropsy of an equine fetus aborted at 9 months of gestation reveals multifocal pinpoint hepatic necrosis and severe pulmonary edema. What is the likely etiology of the abortion?
Definition
EHV-1
Term
Which bacterium is the causative agent of "circling disease"
Definition
listeria monocytogenes
Term
Which commonly used class of OTC human medicaitons is often associated with gastric erosive-ulcerative disease and may also cause acute renal failure?
Definition
NSAIDS
Term
Immune-mediated polyarthritis is the result of which type of immune reaction?
Definition
Type III
Term
Bovine pyelonephritis and ovine posthitis ("pizzle rot") are associated with infection with which organism?
Definition
Corynebacterium renale
Term
Amoxicillin, Metronidazole, or Trimethoprim-sulfa. Which of these is the most appropriate oral antibiotic treatment for giardiasis?
Definition
Metronidazole. Fenbendazole is the treatment of choice.
Term
Plants of the genus Lantana can be toxic to cattle. Which 2 organ systems are affected?
Definition
Liver (hepatotoxicosis), Integument (photoxicosis)
Term
Brightly-colored ornamental beads made from tropical seed pods and used for jewelry classically contain which toxin?
Definition
Castor bean
Term
Pimobendan exerts its effect via which mechanism?
Definition
PDE (phosphodiesterase inhibitor) and Calcium sensitization; increases myocardial contractility and arterial dilation
Term
Which physiologic stimulus leads to ADH release from the pituitary?
Definition
increased plasma osmolality
Term
Which antibiotic is best known for causing esophageal strictures in cats?
Definition
Doxycycline
Term
If nystagmus changes direction with head position, is the vestibular lesion most likely peripheral or central?
Definition
central. Nystagmus due to peripheral (middle/inner ear) lesions does not change directions with changes in head position
Term
Does chocolate toxicosis cause an increase or a decrease in CNS activity?
Definition
increase
Term
Which bacterium is most commonly impacted in cases of pyoderma in the dog?
Definition
Staph pseudintermedius
Term
In cants and dogs, the presence of renal tubular necrosis with large numbers of intratubular calcium oxalate crystals on microscopic examination of the kidney is characteristicc of which chemical intoxication?
Definition
Ethylene glycol
Term
A deficiency in these nutrients is associated with muscle necrosis and mineralization in calves, lambs, and foals (White Muscle Disease). Name the nutrients.
Definition
Selenium & vitamin E
Term
How many types of toxin are produced by Clostridium botulinum, and what are they?
Definition
Seven: A,B,C1,D,E,F,G. A,B,E,F cause human disease. C & D cause disease in birds and mammals. (>99% of canine cases are caused by type C)
Term
What is the causative agent of Q Fever?
Definition
Coxiella burnetii
Term
Treatment of adult heartworm infection in dogs now involves administration of doxycycline in addition to adulticide drugs. Why?
Definition
Wohlbachia spp. - a bacteria that live inside heartworms and without which the worms are weakened and mroe susceptible to adulticide drugs
Term
The anti-ulcer drug omeprazole functions by which mechanism?
Definition
proton-pump inhibitor of the gastric parietal cell (inhibits H+/K+/ATPase pump)
Term
What is the most common histologic diagnosis in feline mammary tumors?
Definition
adenocarcinoma
Term
What is the causative agent of infectious canine thrombocytopenia?
Definition
Anaplasma platys
Term
Canine distemper virus is a member of which genus and family?
Definition
Genus: Morbillivirus; Family: paramyxoviridae
Term
postmortem examination of a sheep with a history of decreased appetite, diarrhea, and wasting reveals marked irregular thickening of the abomasal wall with a convoluted appearance (sometimes likened to Morocco leather). What is the most likely cause?
Definition
Ostertagia circumcincta
Term
What is the mechanism of action of toxicosis from ingestion of Poinsettia plants?
Definition
oral mucosal irritation
Term
Nigropalladial encephalomalacia (necrosis of the substantia nigra) is the characteristic lesion of which plant toxicosis in horses?
Definition
Yellow Star Thistle (Russia Knapweed)
Term
A serum deficiency in which electrolyte causes muscular weakness and cardiac conduction disturbances due to decreased cell membrane excitability?
Definition
K+
Term
Name the medication used in the treatment of hyperadrenocorticism that blocks the conversion of pregnenolone to progesterone in the adrenal gland?
Definition
Trilostane
Term
The descending loop of Henle is: A) permeable to water but rather impermeable to solute or B) rather impermeable to water but permeable to solute?
Definition
A) permeable to water but rather impermeable to solute
Term
What is the main excitatory neurotransmitter in the brain and spinal cord?
Definition
Glutamate
Term
Total body water makes up approximately which percentage of the total body weight in healthy, non-obese adult animals?
Definition
60%
Term
Which gram-negative bacterium is the causative agent of plague?http://www.flashcardmachine.com/my-flashcards/quick-editor.cgi?topic_id=2020728&row_offset=100
Definition
Yersina pestis
Term
Anticoagulant rodenticides inhibit the activation of all these coagulation factors with the exception of ...? II, III, VII, IX, or X
Definition
Factor III
Term
Doramectin, milbemycin, and abamectin belong to which class of antiparasitic drugs?
Definition
Macrolides
Term
On which part of the kidney does furosemide exert its primary diuretic effects?
Definition
Thick ascending loop of Henle
Term
What are the mechanism and site of diuretic action of spironolactone?
Definition
Late distal tubule and Collecting duct of the nephron; Antagonize aldosterone
Term
Macrophages are derived from which circulating blood cell?
Definition
Monocyte
Term
In health, approximately how long does a neutrophil stay in the blood?
Definition
10 h
Term
A dog has seizures and hyperthermia. The owners recently "treated" their yard due to a snail infestation. What is the likely toxin?
Definition
Metaldehyde
Term
Which cytologic changes in nuclear morphology are characteristic of neoplastic cells and are criteria for malignancy?
Definition
Presence of nucleoli, anisokaryosis, clumped chromatin, high nuclear to cytoplasmic ratio
Term
What is the most sensitive and specific blood test for the diagnosis of canine and feline pacreatitis?
Definition
Species-specific serum pancreatic lipase (pLI)
Term
Which urinary stones are radiopaque, and which are not?
Definition
Most radiopaque: calcium phosphate, calcium oxalate, struvite,

Least: cystine and urate ("I can't CU")

Term
Feline asthma is characterized by which radiographic findings?
Definition
bronchial pattern, hyperinflation of lungs, increased lung radiolucency, flattened diaphragm, normal radiographs do not rule our asthma
Term
Hyperglycemia, glucosuria, ketonuria, and metabolic acidosis are the hallmark findings of which endocrine disorder?
Definition
Diabetes ketoacidosis
Term
What avian blood cell (granulocyte) is analogous to the mammalian neutrophil?
Definition
Heterophil
Term
A puppy with respiratory signs, conjunctivitis, vomiting and bloody diarrhea is suspected to have distemper. What is the diagnostic test of choice?
Definition
Indirect fluorescent antibody test of conjuctival swabs, or white blood cells from circulating blood, or blood searms for virus isolation
Term
Which type of urinary crystal is observed in normal Dalmatian dogs or dogs with liver disease?
Definition
Ammonium biurate
Term
When a standing lateral thoracic radiograph of a horse is taken, which lung is most clearly seen: the lung field closest to the cassette, or the opposite lung field?
Definition
Lung field closest to the cassette. The opposite lung field gets distorted due to the great width of the equine chest.
Term
Decreased production of which substance causes non-regenerative anemia in animals with chronic kidney disease?
Definition
erythropoietin (EPO)
Term
A right lateral radiograph of a dog's abdomen shows a gas distended stomach. There is a reverse C sign appearance to the stomach. What is the diagnosis?
Definition
Gastric dilatation volvulus (GDV)
Term
At which sites in the canine stifle does osteochondrosis dissecans (OCD) occur most commonly?
Definition
Lateral and medial femoral conyles
Term
In dogs and cats, what is the most reliable blood test for detecting liver disease such as portosystemic shunt (PSS)?
Definition
Serum bile acids (elevated postprandial bile acid level)
Term
Name a circulating cardiac biomarker that indicates elevated intraventricular pressures (as seen with congestive heart failure) and another cardiac biomarker that indicates myocardial damage (as seen with myocarditis)?
Definition
Elevated intraventricular pressure: natriuretic peptides (NT-proBNP or B-type natriuretic peptide)

Myocardial damage: cardiac troponins, cTn-1 and cTn-T

Term
Which diagnostic procedure differentiates hematuria from hemoglobinuria and myoglobinuria?
Definition
Urine sediment analysis
Term
Which of the following does polymerase chain reaction (PCR) detect: 1)antibody; 2)protein; C)nucleic acid; or d)antigen?
Definition
nucleic acid
Term
What are typical radiographic features of advanced but compensated ("asymptomatic" or "murmur only") chronic mitral valve insufficiency in dogs?
Definition
left atrial enlargement, left-sided cardiomegaly, possibly pulmonary venous enlargement; absence of an interstitial pattern (no pulmonary edema)
Term
An electrocardiogram shows unusually tall P waves. What structural change in the heart is suspected, and what is the Latin term that describes tall P waves associated which such a change?
Definition
Right atrial enlargement. "P pulmonale"
Term
In a case of septic peritonitits, is the blood glucose concentration higher or lower than the glucose level in the free abdominal fluid?
Definition
Higher, generally >20 mg/dl (>1.1 mmol/L) difference. This is attributed to anaerobic glycolysis by leukocytes in the abdominal exudate.
Term
In patients that suffer from Addison's disease (hypoadrenocorticism), what are the two most common electrolyte disturbances?
Definition
Hyperkalemia and hyponatremia
Term
With hepatic lipidosis in cats, on ultrasound examination is the liver hyperechoic or hypoechoic?
Definition
Hyperechoic (fatty infiltrate). "big and bright"
Term
Is the ELISA test for Johne's disease more sensitive when used in clinically diseased animals or in subclinically infected animals?
Definition
clinically diseased
Term
What is the typical acid/base abnormality found with ethylene glycol toxicosis?
Definition
metabolic acidosis
Term
Name 3 screening tests for hyperadrenocorticism in the dog?
Definition
Low-dose dexamethasone suppression test, urine cortisol:creatinine ratio, adrenocorticopropic hormone stimulation test
Term
Which form of canine hyperadrenocoricism is most likely if a 4-hour serum [cortisol] <50% of baseline is reported on a low-dose dexamethasone suppression test?
Definition
Pituitary dependent hyperadrenocorticism, because this result indicates suppression. A primary adrenocortical tumor would be associated with [cortisol] >50% (failure to suppress)
Term
In the canine hemogram, which changes constitute a stress leukogram?
Definition
neutrophilia, lymphopenia, eosinopenia, monocytosis
Term
Which diagnostic test is most likely to help determine whether the patient is truly hypothyroid or is affected by euthyroid sick syndrome?
Definition
Free T4 by equillibrium dialysis; total T4 and concurrent thyroid stimulating hormone (TSH) measurements are also acceptable
Term
What are the radiographic signs of left-sided congestive heart failure?
Definition
Pulmonary venous enlargement, unstructured interstitial pattern (right caudal lung lobe often affected first in the dog), possibly pleural effusion (cats)
Term
What is the difference between an osteophyte and an enthesiophyte?
Definition
osteophyte: bony outgrowths caused by abnormal joint wear in osteoarthritis, seen at articular cartilage margins.

enthesiophytes: bony outgrowths at an enthesis (where soft tissue inserts on bone [tendon, joint capsule, ligament or fascial])

Term
Name 3 radiographic signs of osteoarthritis?
Definition
Joint effusion; widening and/or thinning of radiolucent joint space; enthesiophyte formation on non-weight bearing surfaces; remodeling of subchondral bone; mineralization of intraarticular and periarticular soft tissues; formation of subchondral cysts; sublusxation (coxofemoral)
Term
Which structure, producing the "sail sign" might be seen cranial to the heart on a ventrodorsal thoracic radiograph of a young dog?
Definition
Thymus
Term
Central diabetes insipidus can be differentiated from nephrogenic diabetes insipidus using which test?
Definition
ADH response test. Note that a water deprivation test does not distinguish between central and nephrogenic forms.
Term
When performing a thoracocentesis, should you advance the needle into the thorax off the cranial or caudal aspect of the rib?
Definition
Cranial aspect to avoid the intercostal vessels and nerves located (projected) caudal to each rib
Term
Which characteristic finding is seen in a fresh saline preparation of whole blood from a dog with immune-mediated hemolytic anemia (IMHA), and what is its major differential diagnosis (microscopically)?
Definition
In-saline autoagglutination; not to be confused with rouleaux formation (roll-of-coins appearance)
Term
A mild neutrophilia, a mild monocytosis and a moderate lymphopenia in a car are most compatible with which of the following: stress (cortisol effects), excitement (epinephrine effects), or inflammation?
Definition
Stress (cortisol effects)
Term
Which fecal diagnostic test is optimal for identifying Cryptosporidium oocysts?
Definition
Flotation with saturated sugar (centrifugaion will improve recovery of oocysts)
Term
What is the most likely source of high serum gamma glutamyltransferase (GGT) levels in a 1 week-old calf?
Definition
Passive transfer through colostrum
Term
Would severe hemophilia A be expected to result in a prolonged prothrombin time (PT), a prolonged partial thromboplastin time (PTT) or both?
Definition
prolonged partial thromboplastin time (PTT) - factor VIII deficiency
Term
A normal prothrombin time (PT), prolonged partial thromboplastin time (PTT) and a normal thrombin time (TT) fits with an abnormality in which part of the coagulation cascade - common, extrinsic or intrinsic?
Definition
Instrinsic
Term
During which season is blastomycosis most commonly diagnosed in North America
Definition
Fall, likely due to increase moisture content of soil (allowing release of fungal spores)
Term
Which event in the heart is represented by the T wave on an electrocardiogram?
Definition
Ventricular repolarization
Term
When sampling the lower respiratory tract of a horse with suspected bacterial pneumonia, which diagnostic procedure is preferred for obtaining a bacterial culture sample?
Definition
Tracheal aspiration (bronchoalveolar lavage is for cytology only)
Term
Patients with acute hemorrhagic diarrhea can rapidly lose large amounts of fluid from the GI tract. What is a common abnormality noted initially on a CBC in such patients?
Definition
Elevated PCV (relative polycythemia from hemoconcentration)
Term
On ECG, P waves occur at regular intervals, and wide, bizarre QRS complexes occur at a much slower rate, unrelated to the P waves. What is the diagnosis?
Definition
Third degree (complete) AV block. The wide, bizarre QRS complexes are ventricular escape beats.
Term
Which test is currently the most widely used and preferred method of diagnosing rabies infection in animals?
Definition
Direct fluorescent antibody testing (DFAT) of brain tissue
Term
On an echocardiogram, an anechoic (black) space is apparent adjacent to the epicardium. What is the diagnosis?
Definition
Pericardial effusion
Term
Anal sac adenocarcinoma is commonly associated with which serum biochemical abnormality?
Definition
Hypercalcemia
Term
An audible S4 gallop on auscultation is usually associated with what type of lesion of the ventricles?
Definition
Hypertrophy and stiffness. It occurs due to the resonance/vibration of ventricular walls during end-diastole (atrial contribution to ventricular filling)
Term
Arrhythmogenic right ventricular cardiomyopathy (formerly called Boxer cardiomyopathy) is characterized by which type of cardiac arrhythmia?
Definition
Premature ventricular complexes (right-sided) and ventricular tachycardia
Term
Name 2 erythrocyte features that are normal in Akitas but are not found in most other dog breeds?
Definition
Microcytosis (or low mean corpuscular volume) and very high intracellular potassium. Thus, in this breed and other Japanese breeds (Shiba Inu, Tosa Inu), in vitro hemolysis can cause marked (but artifactual) hyperkalemia.
Term
Does the feline leukemia (FeLV) ELISA test detect antigen, antibody, or both?
Definition
Antigen only. This is why the result is unaffected by previous vaccination.
Term
What is the most reliable diagnostic test for feline hypertrophic cardiomyopathy?
Definition
An echocardiogram. Genetic testing of a blood sample for the beta-myosin heavy chain mutation is simpler but less reliable (many false negatives).
Term
When performing pericardiocentesis, which intercostal space should be entered, and at which landmark?
Definition
5th ICS, at the costochondral junction (typically from the right side to minimize the risk of catheter-induced coronary artery laceration)
Term
Which form of Blastomyces dermatitidis is most commonly found on cytological or histopathological preparations of infected tissues?
Definition
Yeasts (classical broad-based budding). Never cultured in-house (risk of aerosol transmission causing zoonosis)
Term
Whcih forms of Coccidioides immitis may be found on cytological or histopathological preparations of infected tissues?
Definition
Spherules (containing endospores). Never culture in-house because aerosolization causes zoonosis.
Term
What is the most common serum biochemical abnormality in dogs with primary hypothyroidism?
Definition
Fasting hypercholesterolemia
Term
Where would you expect to find the point of maximal intensity (PMI) of a murmur associated with tricuspid insufficiency?
Definition
Right side of thorax, over the cardiac apex (approximately 4th ICS)
Term
What is the diagnostic test of choice for confirming chlamydophilosis in a pet bird?
Definition
Histologic or cytologic demonstration of the organism (elementary bodies) in smears, fluids, or tissue. PCR demonstration of DNA, or specialized culture isolation, are also possible but less practical.
Term
What is the name of the ultrasound principle that provides information on velocity and direction of blood flow?
Definition
Doppler (color or spectral [pulsed-or continuous wave])
Term
Acid-fast, intranuclear inclusions in the proximal convoluting tubular epithelium are diagnostic for?
Definition
Lead poisoning
Term
Which serum liver enzyme may be elevated due to normal bone growth or exposure to corticosteroids in dogs?
Definition
Alkaline phosphatase (ALP)
Term
On radiographs of the equine tarsus, where are the 2 most common locations of osteochondrosis?
Definition
1) Cranial aspect of the intermediate ridge of the distal tibia, 2) lateral trochlear ridge of the talus
Term
Laminar cerebrocortical necrosis and eosinophils in the meninges and Virchow-Robin spaces are characteristic histopathological findings of which disease of swine?
Definition
Salt toxicity (sodium poisoning and water intoxication)
Term
Which endocrine test should be performed on an animal with gastrointestinal signs, lethargy, and the lack of a stress leukogram on its CBC?
Definition
Adrenocorticotropic hormone stimulation test (rule in or out hypoadrenocorticism)
Term
Which cardiac arrhythmia is most commonly noted in dogs with GDV?
Definition
Premature ventricular complexes (PVCs). some patients also develop transient atrial fibrillation, often if fluid resuscitated rapidly and treated with opioid drugs.
Term
Tortuous pulmonary arteries, right ventricular enlargement, and a main pulmonary artery bulge are radiographically suggestive of which infectious disease of dogs?
Definition
Heartworm disease
Term
What does an elevated serum l-lactate value indicate? How would this affect the anion gap?
Definition
Poor tissue perfusion, decreased oxygenation, anaerobic respiration. It would result in an increased anion gap.
Term
Approximately which percentage of the funcational hepatocytes must be lost before alteratations of hepatic function are detectable by serum biochemical testing?
Definition
70%. Indicators of hepatic function (bilirubin, albumin, cholesterol) are distinct from hepatic damage (ALT, AST, etc.) - a common oversight.
Term
Besides the liver, elevations in aminotransferase (AST) may originate from which other tissue?
Definition
Muscle, and minscule amounts from the kidney, RBCs, brain, and placenta
Term
Adequate renal concentrating ability is presumed to exist if the urine specific gravity (USG) is greater than which value in dogs?
Definition
1.030
Term
In cats, at which approximate absolute reticulocyte count would you say regeneration is occuring?
Definition
>60,000/microliter = regenerative response, though 50,000/microliter could still be classified as a "slight" degree of regeneration
Term
What is the most common cause of macrocytosis?
Definition
Reticulocytosis, typically as part of a regenerative anemia
Term
With a primary glomerular disease, would you expect a mild, moderate, or severe proteinuria?
Definition
Severe proteinuria with urine protein: urine creatinine ratios often >3 and usually >5
Term
After approximatley how many days would you expect to see signs of regeneration following acute blood loss in a dog?
Definition
2-3 days, and reach maximum regeneration approximately 7 days post onset of hemorrhage
Term
The minimum inhibitory concentration (MIC) breakpoint for Ampicillin is
Definition
Sensitive
Term
You suspect an outbreak of Marek's disease in chickens. Name 2 diagnostic tests that can be useful for confirming diagnosis.
Definition
Histopathological examination of nerevs and tumors; PCR; Virus isolation; bird challenge experiments; serologic titers only in specific pathogen-free (SPF) flocks.
Term
Which percentage of dogs with appendicular osteosarcoma have pulmonary metastasis visible on thoracic radiographs at the time of diagnosis: <10%, 15-30%, 40-60%, or >75%?
Definition
<10%
Term
In a dog, what are parameters that allow you to determine whether the diameter of the small intestine is enlarged on a radiograph?
Definition
The normal diameter of the jejunum should not exceed 2x the width of a rib and not exceed the height of the central part of the vertebral body of the second lumbar vertebra
Term
On a cat's radiograph, the normal diameter of the jejunum should not exceed...
Definition
12 mm, or twice the height of the central portion of L4
Term
Which 2 abnormal erythrocyte morphologies are associated with canine splenic hemangiosarcoma?
Definition
Schistocytes & Acanthocytes
Term
Which species normally has the least prominent retinal vessels on funduscopic visualization of the optic disk: ovine, bovine, equine, canine, or feline?
Definition
Equine
Term
What is the purpose of gonioscopy?
Definition
To assess the iridocorneal angle for sings that could indicate predisposition to glaucoma (narrow/closed/obstructed iridocorneal angle)
Term
On a patient's electrocardiogram, ST segment depression becomes apparent. What does this usually indicate?
Definition
Myocardial hypoxia
Term
When would you expect to see reticulocytes in the blood of horses?
Definition
Never. Reticulocytes are absent in the blood of horses, both in health and regenerative anemias.
Term
Which is more echogenic in the dog and cat: the liver or the spleen?
Definition
The Spleen is usually slightly more echogenic (also has a finer/less coarse echotexture)
Term
A normal cat's abdominal ultrasound image shows 2 gallbladders within 2 livers, one of each on each side of the diaphragm. How is this observation explained?
Definition
Mirror-image artifact, a result of reflection of ultrasound waves on the concave surface of the diaphragm
Term
Which common fungal organism has a distinguishing polysaccharide capsule?
Definition
Cryptococcus spp.
Term
Cats with acetaminophen toxicosis can present with which hemoglobin abnormality?
Definition
Methemoglobinemia
Term
What is the simplest test for confirming patency of the nasolacrimal duct (Jones Test)?
Definition
Application of fluorescein stain on the eye, and observation for its emergence at the nasolacrimal puncta
Term
Why does a very deep corneal ulcer show no central uptake of fluorescein?
Definition
Descemet's membrane does not retain fluorescein stian (desmetocele). Beware of perforation at this stage - no juglar pressure, and use caution when handling the eye/administering ocular medications.
Term
What is the purpose of using a Schiotz tonometer?
Definition
Measuring intraocular pressure (IOP) (glaucoma, uveitis)
Term
Describe the expected serum ionized calcium, parathyroid hormone (PTH), and parathyroid hormone related protein (PTHrP) concentrations in primary hyperparathyroidism.
Definition
Elevated ionized calcium with normal to elevated PTH, or normal ionized calcium with elevated PTH; undetectable PTHrP in either case
Term
Which ultrasound mode is most useful for precisely measuring the dimensions and relative movements of the left ventricle over several heartbeats: A-mode, B-mode, or M-mode?
Definition
M-mode. The name is a contraction of "Motion-mode", which is an obsolete, 1-dimensional modality from the early days of ultrasonography.
Term
Wood's lamp examination, direct microscopic hair examination, and culture with microscopic identification are tests used for diagnosing which zoonotic, cutaneous disease of dogs and cats?
Definition
Dermatophytosis
Term
Unlike dogs, which serum liver enzyme in cats is not easily affected by corticosteroid exposure?
Definition
Alkaline phosphatase (ALP)
Term
Which group of dog breeds has higher Hct values than established reference ranges for other breeds?
Definition
Sight hounds (greyhounds, Afghan hounds, etc.)
Term
In a biopsy specimen from a patient with hepatic amyloidosis, in which anatomic region does the amyloid accumulate?
Definition
Space of Disse
Term
Name two ways to confirm a suspected diagnosis of retinal detachment in a blind animal?
Definition
Fundic examination and ocular ultrasound examination. Only ultrasound is effective if there is severe hyphema, obscuring the anterior and posterior chambers.
Term
During echocardiography, the left atrium is usually compared to which structure for deciding whether left atrial enlargement is present? (a ratio of about 1:1 s expected in most animals)
Definition
Aorta. The proximal aortia is achored tothe fibrous cardiac skeleton and therefor almost never changes in size with any heart disease, making it an excellent reference point.
Term
Which bacterium is most commonly isolated in uncomplicated canine infectious tracheobronchitis?
Definition
Bordetella bronchiseptica. Mycoplasma spp. is also acceptable (though rarely cultured). Several other bacterial species may be involved later as secondary opportunists.
Term
In patients that suffer from Addison's disease (hypoadrenocorticism), what are the two most common electrolyte disturbances?
Definition
Hyperkalemia and hyponatremia. Azotemia (especially BUN elevation), hypoalbuminemia, hypoglycemia, and hypercalcemia can also occur.
Term
What blood type is considered the universal donor?
Definition
Dog erythrocyte antigen (DEA) 1.1, 1.2, 3, 4, 5, and 7 negative. For practical purposes, DEA 1.1 negative is considered sufficient by some clinicians.
Term
What is the most common cause of hypercalcemia in cats?
Definition
Idiopathic (unlike the dog, where malignancy-associated hypercalcemia is more common)
Term
Other than idiopathic disease, what are the 2 major causes of non-traumatic chylothorax in the cat?
Definition
Neoplasia (mediastinal lymphoma), congestive heart failure
Term
What is the most common cause of canine maternal origin dystocia and how is it treated?
Definition
Uterine inertia; oxytocin, or if ineffective, caesarean section
Term
What type of diet may aid in reducing insulin requirements and improve clinical diabetic control in cats?
Definition
Low simple-carbohydrate, high protein, high-fiber diet
Term
Which four pathological conditions are associated with canine elbow dysplasia?
Definition
1)FCP-fragmented medial coronoid process, 2) UAP-ununited anconeal process, 3) OCD-osteochondrosis, 4) elbow incongruity
Term
What is the most commonly diagnosed neoplasm in the cat?
Definition
Lymphoma
Term
Why should a pregnant bitch's diet not be supplemented with calcium?
Definition
Excessive intake of calcium during pregnancy may predispose the bitch to puerperal tetany (eclampsia) during lactation)
Term
What is the most common cause of hypoglycemia in the dog?
Definition
Insulinoma (beta-islet cell tumor)
Term
What is the most common brain tumor in cats and dogs?
Definition
Meningioma
Term
Which dog breeds are predisposed to development of exocrine pancreatic insufficiency (EPI)?
Definition
German shepherd dog (GSD), rough coated collie, cavalier King Charles spanial, chow chow
Term
Your patient is a 2-year-old male castrated German shepherd dog with a chief complaint of regurgitation; the acetylcholine receptor antibody test is strongly positive. What is the diagnosis?
Definition
Myasthenia gravis causing megaesophagus
Term
Which group of antimicrobials is recommended to treat feline hemotrophic mycoplasmosis?
Definition
Tetracyclines. Doxycycline is preferred, with a recommended treatment duration of 3 weeks.
Term
What is the name of a rare complication of hypothyroidism characterized by nonpitting thickening of the skin, especially of the eyelids, cheeks, and forehead?
Definition
Myxedema
Term
Which secondary organ is most commonly affected by systemic hypertension in the dog and cat?
Definition
The eye (retinal hemorrhage, retinal detachment)
Term
Which algae species found in soil, sewage, and tree slime flux causes large bowel diarrhea, CNS signs, and ocular manifestations in dogs?
Definition
Prototheca spp.
Term
Which two theraputic agents can be used for treating cats with clinical Aelurostrongylus abstrusus infection?
Definition
Fenbendazole and Ivermectin
Term
The Cavalier King Charles spaniel breed of dog is predisposed to which cardiac disease?
Definition
Chronic degenerative atrioventricular valve disease (endocardiosis or myxomatous valvular degeneration)
Term
What is the typical signalment of dogs affected by fibrocartilagenous embolism?
Definition
Adult, large and giant breed, non-chondrodystrophic breeds
Term
While all mammals are susceptible, generally this toxicosis is seen in cats fed a diet high in raw liver. What is it?
Definition
Vitamin A toxicosis
Term
Name 3 treatments for hyperthyroidism in cats?
Definition
Radioactive iodine therapy, surgical removal of the gland, and antithyroid drugs (methimazole, carbimazole, ipodate)
Term
In everyday practice, what is the treatment of choice for benign prostatic hyperplasia (BPH)?
Definition
Castration; estrogens, progestins, 5-alpha reducatse inhibitors (e.g. finasteride), and gonadotropin releaseing hormone (GnRH) also may help reduce prostatic size
Term
What is the main physical examination finding in dogs with trigeminal neuritis?
Definition
Bilateral paralysis of the masticatory muscles (dropped jaw; inability to close the jaw)
Term
What is a common sequela of feline hypertrophic cardiomyopathy besides congestive heart failure?
Definition
Aortic thromboembolism; rarely syncope or sudden death
Term
Although not pathognomonic, myoclonus is a movement disorder most commonly associated with which specific central nervous systemic (CNS) infection in dogs?
Definition
canine distemper virus (CDV) infection
Term
What are the primary chronic, cumulative side effects of doxorubicin therapy in dogs and cats?
Definition
Cardiomyopathy mainly in dogs; nephrotoxicity in cats
Term
What are some emetics to consider for toxicological emergencies in dogs and cats?
Definition
Dogs: apomorphine, hydrogen peroxide, syrup of ipecac. Cats: medetomidine, xylazine, hydrogen peroxide, syrup of ipecac. Salt is contraindicated due to risk of severe hypernatremia if emesis does not occur.
Term
Which testicular tumor of dogs is known to produce estrogen?
Definition
Sertoli cell tumor (causing feminizing syndrome)
Term
Ingestion of garlic or onions by dogs produces which hematologic disorder?
Definition
Heinz body hemolytic anemia. This is dose-dependent, and toxicity persists even if the onions/garlic are cooked or dried.
Term
How is feline leukemia virus (FeLV) primarily transmitted?
Definition
Close contact, grooming, social behavior (saliva, secretions)
Term
What is the name of the most common tick-borne disease caused by a hemoprotozoan parasite that infects red blood cells (RBCs) of dogs?
Definition
Babesiosis
Term
In dogs affected with Chagas' disease (American trypanosomiasis), which organ is characteristically the site of the most life-threatening lesions?
Definition
The heart. Initially, myocarditits can occur, but in most chronic cases, a dilated cardiomyopathy (DCM)-like syndrome eventually emerges and it is often difficult to treat
Term
In gastric dilation/volvulus, which abnormality of serum potassium is often present?
Definition
Hypokalemia. Serum potassium may further decrease with correction of acidosis.
Term
What is the most commonly described paraneoplastic syndrome related to thymomas in dogs?
Definition
Myasthenia gravis (including megaesophagus)
Term
What is the most common clinical feature of feline hyperthyroidism?
Definition
Weight loss (>80% of cases). Newer case series report clinical signs that are less dramatic, possibly because of earlier detection or disease variation over time.
Term
Which flea species is most commonly associated with dogs and cats?
Definition
Ctenocephalides felis felis
Term
What are the four "Ps" that characterize the clinical signs seen in the distal extremities of cats with aortic thromboembolism?
Definition
Pain, paralysis, pulselessness, pallor. The footpads also are often cool to the touch.
Term
What is the most common cause for hypercholesterolemia and no other complete blood count/serum biochemistry abnormalities in an adult, fasted dog?
Definition
Hypothyroidism
Term
What is the most likely diagnosis in a Basenji dog with a history of polydipsia and polyuria, and glucosuria or urinalysis in the face of a normal blood glucose?
Definition
Fanconi syndrome, an inherited proximal tubular defect that most commonly occurs in this breed.
Term
Why may it be useful to distinguish between superficial and deep corneal vascularization?
Definition
Superficial suggests superfical corneal or external ocular disease; deep suggests corneal stromal or intraocular disease
Term
Which electrolyte disturbance is most common in cats with chronic kidney disease?
Definition
Hypokalmia (note: hyperphosphatemia is also common, but strictly speaking, phosphorous is a mineral, not an electrolyte)
Term
Which NSAID can be used for treating transitional cell carcinoma of the urinary bladder in dogs?
Definition
Piroxicam (brand name: Feldene)
Term
Panosteitis is a disease of dogs of which age group? a)neonatal; b)juvenile; c)middle-aged adult; d)geriatric; e)no age predilection
Definition
b)juvenile dogs
Term
A 10 month-old mixed breed dog presents with exercise intolerance and differential cyanosis. What is your top differential diagnosis?
Definition
Reversed (right to left shunting) patent ductus arteriosus (PDA) is the only malformation that produces cyanosis in the caudal half of the body with normal, pink mucous membranes of the head (differential cyanosis).
Term
A 40 kg dog is presented witha transverese, mildly comminuted fracture of the tibia. Which option for fracture fixation will LEAST likely provide adequate return to function? A)Cerclage wire B)External skeletal fixator C)Bone plate with screws
Definition
A)Cerclage wires
Term
Acetaminophen hepatotoxicity in dogs results primarily form a low level of which enzyme?
Definition
Hepatic glutathione (hence the usefulness of s-adenosylmethionine (SAMe) during treatment)
Term
Feline infectious peritonitis (FIP) is caused by a mutation in which virus?
Definition
Feline enteric coronavirus. since it is an in vivo mutation, a positive serologic titer does not distinguish between coronaviral enteritis and FIP.
Term
A pale, icteric dog has hemoglobinuria and hemoglobinemia. An echocardiogram reveals a mass of worms in the tricuspid valve. Which syndrome does this dog have?
Definition
Caval syndrome (class 4 heartworm disease)
Term
Which of the following is least likely to produce ventricular premature complexes (VPCs) in dogs or cats: blunt chest trauma, hypercalcemia, splenic mass, hypokalemia?
Definition
Hypercalcemia, which raises the threshold for depolarization (i.e., decreases arrhythomogenicity). The others are commonly associated with VPCs.
Term
What is the difference between Hansen type I and type II intervertebral disk disease?
Definition
Hansen type I: acute extrusion of nucleus pulposus into vertebral canal; Hansen type II: slow chronic protrusion of annulus fibrosis into vertebral canal
Term
Where are the most common site for intussuception to occur in a small animal?
Definition
ileocolic and jejunojejunal; however they can occur anywhere in the gastrointestinal tract
Term
Which nontraumatic disease is the most common cause for petechiae and ecchymoses in the adult dog?
Definition
Immune-mediated thrombocytopenia (not anticoagulant toxicosis, which instead produces signs of factor deficiency: overt bleeding, bleeding into body cavities, etc.)
Term
What is the most common cause of constipation/obstipation in the cat?
Definition
Idiopathic megacolon
Term
What is the protocol for leptospirosis vaccination for dogs living in endemic areas?
Definition
Initially during puppyhood: 3 vaccinations @ 3-4 weeks apart, then at least every 6 months. Leptospira titers are present for only 3-6 months.
Term
An older Shetland sheepdog has had lethargy, anorexia and bone pain for weeks. Bone marrow plasmacytosis and osteolytic bone lesions are present. What is the most likely diagnosis?
Definition
Multiple myeloma
Term
This skin tumor, the most common cutaneous malignancy in the dog, cause gastric ulcers and Darier's sign.
Definition
Mast cell tumor. Darier's sign is the local erythema (due to mast cell degranulation) seen after physical manipulation of a mast cell tumor).
Term
Which organ system is most commonly affected when lymphoma occurs in a feline leukemia virus-negative cat?
Definition
Gastrointestinal tract (alimentary lymphoma)
Term
Lung lobe torsion most commonly occurs in which lobe of large breed dogs?
Definition
Right middle lobe. Afghan hounds are overrepresented; many pugs also have been diagnosed with lung lobe torsion.
Term
Which IV fluid would be most appropriate for resuscitation of a patient in an acute hypoadrenocortical (Addisonian) crisis?
Definition
0.9% sodium chloride to treate hyponatremia (no potassium, because the hyperkalemia is usually present in crisis)
Term
What is the most common cause of death in dogs with immune-mediated hemolytic anemia (IMHA)?
Definition
Thromboembolism ("not" anemia)
Term
Which body system is mainly affected in cases of metronidazole toxicosis in dogs?
Definition
CNS
Term
What are the feline blood types?
Definition
Types A, B, and AB
Term
In cryptorchid dogs or cats, which testicle is more likely to be retained?
Definition
Right (2x as likely to be retained as the left)
Term
Why is it useful to determine the immunophenotype (T cell or B cell) of canine lymphoma?
Definition
Because dogs with T cell (CD3 immunoreactive) lymphoma have been reported to have shorter remission and survival durations (memory aid: "B is bad, T is terrible").
Term
What is the most common cause of hypercalcemia of malignancy in the dog?
Definition
Lymphoma (most common anatomic site is cranial mediastinum)
Term
A dog with a head tilt to the left, vertical nystagmus, ataxia, absent facial sensation ipsilaterally, and poor proprioception of the left forelimbs and hindlimbs has a neurological lesion of which specific anatomical location?
Definition
Left-sided central vestibular system (medulla, cerebellar peduncles, cerebellum, or combination)
Term
A middle-aged cat has upper respiratory tract infection, bilateral conjunctivitis, and a dendritic ulcer. This is most consistent with which infectious disease?
Definition
Feline herpesvirus 1 (FHV-1)
Term
Which 3 ingredients account for close to 90% of all adverse food reactions in cats?
Definition
Beef, dairy products, fish
Term
In growing dogs, the anconeal process should be fused to the olecranon within what time frame?
Definition
150 days (~5 months) of age
Term
Infection with which tick-borne parasite causes cyclic thrombocytopenia in dogs?
Definition
Anaplasma platys (formerly Ehrlichia platys)
Term
Name the hydrophillic bile acid commonly used in the treatment of hepatobiliary disease in the dog and cat. What is the main contraindication to its use?
Definition
Ursodeoxycholic acid (urodiol or decholate). Contraindicated with gallbladder obstruction because it induces gallbladder contraction.
Term
What is the most common adverse effect of acetaminophen? Are dogs or cats more susceptible to an equivalent dose?
Definition
Methemoglobinemia causing life-threatening hemolytic anemia. Cats are much more susceptible to toxic effects (develop toxicosis at lower doses and have more severe signs at equivalent doses).
Term
What type of heart disease is most common in the doberman breed?
Definition
Dilated cardiomyopathy
Term
In dogs with traumatic coxofemoral luxation, what is the most common direction of displacement of the femoral head?
Definition
Craniodorsal displacement
Term
Name 3 disorders that cause insulin resistance in the dog.
Definition
Hyperadrenocorticism, hypothyroidism, diestrus, glucagonoma, pacreatitis, exocrine pancreatic insufficiency (EPI), congestive heart failure (CHF), and infection
Term
What is the mechanism of polyuria/polydypsia in the dog with pyometra?
Definition
E. coli endotoxin interferes with antidiuretic hormone in the renal tubule
Term
With which canine breed is malignant histiocytosis most commonly associated?
Definition
Burmese mountain dog
Term
What is the major route of infection for Coccidioides immitis in dogs and what is the name of the infectious spore stage of the organism?
Definition
Airborne infection (inhalation of arthroconidia from dry desert topsoil)
Term
Which type of tumor should be suspected in a dog with unilateral thoracic limb lameness and ipsilateral Horner's syndrome?
Definition
Nerve sheath tumor (T1 or T2 nerve roots are affected; deep palpation cranial to the first rib may elicit a pain response)
Term
Dogs (and humans) mainly acquire blastomycosis via which route?
Definition
Inhalation of conidia from the environement
Term
Which vaccine adjuvant has been implicated in injection-site sarcomas of cats?
Definition
Aluminum hydroxide
Term
What are the 2 most common congeintal heart defects in the dog?
Definition
Patent ductus arteriosus (PDA) and Subaortic stenosis (SAS)
Term
What is the infective larval stage of Dirofilaria immitis (heartworm)?
Definition
L3, which the mosquito deposits into the animal during a bloodmeal and which travels through the host's tissues for 70-120 days on its way to the venous circulation
Term
An older male, intact dog is incidentally-discovered symmetrical nonpainful prostatomegaly on rectal examination. What is the top differential diagnosis?
Definition
Benign prostatic hyperplasia
Term
What is the most common hereditary feline coagulation factor deficiency?
Definition
Factor XII deficiency (Hageman trait)
Term
During which phase of the estrous cycle does pyometra usually occur in dogs?
Definition
Diestrus
Term
What is the most common etiology of canine hypothyroidism?
Definition
Primary hypothoyroidism (destruction of the thyroid gland itself) by lymphocytic thryroiditis or idiopathic thyroid atrophy. Secondary (pituitary lesion) and tertiary (hypothalamic lesion) are very rare.
Term
What is the most common etiology of hyperadrenocorticism in the dog?
Definition
Pituitary-dependent hyperadrenocorticism characterized by overproduction of adrenocorticotropic hormone (ACTH) in the pituitary gland and secondary oversecretion of adrenocortical hormones
Term
Name the resiratory deformity of the older, small, and miniature-breed dogs that is classically characterized by a "goose-honk" type cough.
Definition
Collapsing trachea
Term
Which ornamental flower has been implicated in the greatest number of cases of acute renal failure in cats?
Definition
Lilium spp. (lillies)
Term
Which endocrine abnormality is known to cause cataract formation in the dog?
Definition
Diabetes mellitus
Term
During cranial cruciate ligament repair, the meniscal attachments often are deliberately transected. This procedure is known as:
Definition
Meniscal release. The purpose is to offer greater meniscal mobility to reduce the likelihood of meniscal injury.
Term
With splenectomy alone, expected median survival times for dogs with splenic hemangiosarcoma is: A)19-86 days B)103-155 day C)297-392 days
Definition
A)19-86 days
Term
Surgical reduction of a pelvic fracture typically may no longer be possible after how many days: 2, 4, or 7?
Definition
7
Term
A dog hit by a car has bilateral hindlimb paralysis and forelimb extensor hypertonia, with preserved voluntary movement and proprioception in the forelimbs. What is the term for this posture? Where it the lesion?
Definition
Schiff-Sherrington psoture; thoracic or cranial lumbar spinal cord
Term
What are two drugs that act on sodium channels and thus have been used in the therapy for canine distemper-induced myoclonus?
Definition
Lidocaine and Procainamide. They are more commonly used for their cardiac antiarrhythmic effects, or local anesthetic effects (lidocaine)
Term
An adult cat has anorexia and bilateral mucopurulent nasal discharge. The owner has a flock of messenger pigeons. Which infection in dogs and cats is most likely responsible?
Definition
Cryptococcosis (Cryptococcus neoformans infection)
Term
Which type of urolith is most likely to be found in a dog with a portosystemic shunt?
Definition
Ammonium urate
Term
Stomatitis in cats can be assicated with which viruses?
Definition
Feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), calcivirus, and feline herpesvirus
Term
Is fremitus of the middle uterine artery in the bovine considered a cardinal sign of pregnancy? At which gestational age is it first detectable?
Definition
It is not considered a cardinal sign of pregnancy (too variable), but when it is present, it is first detectable from 110-150 days of gestation
Term
Which 2 body systems are most commonly affected in the crhonic form of infection with Erysipelothrix rusiopathiae in pigs?
Definition
Musculoskeletal (arthritis) and cardiovascular (endocarditis)
Term
Which breed of cattle is most commonly affected by ocular squamous cell carcinoma?
Definition
Herefords
Term
Which anatomical structure prevents urinary catheterization of bulls?
Definition
Urethral diverticulum
Term
Bovine ulcerative mammilitis is caused by which virus?
Definition
Bovine herpesvirus type 2
Term
What is the most common clinical sign of Mycoplasma hyopneumoniae infection in pigs?
Definition
Chronic, persistent, non-productive cough
Term
What is the normal range of urine pH in ruminants?
Definition
6.0-9.0. A pH > 8.0 can cause a flase-positive reading on protein dipstick squares, which should not be misinterpreted as indicated proteinuria.
Term
What is the most common cause of viral diarrhea in foals?
Definition
Rotavirus
Term
Which immune-mediated ocular disease is one of the most common causes of blindness in horses?
Definition
Equine recurrent uveitis (ERU, "moon blindness")
Term
Name the causative agent of equine ehrlichiosis?
Definition
Anaplasma phagocytophilum
Term
Name 3 systemic infectious diseases associated with ulcerative and/or erosive lesions in the gastrointestinal tract of ruminants?
Definition
bovine viral diarrhea virus (BVDV), rinderpest, malignant catarrhal fever (MCF) (AHv1/OvH2)
Term
Which gross lesion is characteristic of Glasser's disease in pigs?
Definition
Fibrinous polyserositis and meningitis (cause is Haemophilus parasuis infection)
Term
What are two common viral etiologies of respiratory disease in pigs?
Definition
Swine influenza (SIV) and Porcine respiratory and reproductive syndrome (PRRS)
Term
Horses of which breed appear to be predisposed to congenital cardiac defects?
Definition
Arabian
Term
Which parasite that causes diarrhea in 5 to 15 day-old calves is a potential zoonosis?
Definition
Cryptosporidium parvum (cryptosporidiosis is one of the most common causes of protozoal diarrhea in people)
Term
Which vesicular disease causes oral mucosal lesions in pigs, ruminants, and horses?
Definition
Vesicular stomatitis. Foot and mouth disease (FMD) is not infectious to horses.
Term
What is the most common adnexal ocular tumor in the horse, typically seen in breeds such as Belgian, Clydesdale, Appaloosa, and Paint?
Definition
SCC. It occurs commonly on unpigmented/white skin.
Term
Insidious onset but progressive clinical signs of apprehensive behavior, aggressiveness, hyperesthesia, and incoordination, which are mainly seen in older dairy cows, and are indicative of which infectious disease first reported in 1986?
Definition
Bovine spongiform encephalopathy (BSE). The most important differential is rabies, due to its zoonotic potential.
Term
What is the cause of equine coital exanthema?
Definition
Equine herpesvirus 3 (EHV-3)
Term
Which tick-borne disease of cattle is associated with high fever, intravascular hemolysis, neurologic signs, and death?
Definition
Babesiosis (also known as "red water" or "tick fever")
Term
In horses, chronic lower respiratory disease characterized by periods of reversible airway obstruction and neutrophilic pulmonary inflammation is termed:
Definition
Recurrent airway obstruciton (RAO), formerly known as chronic obstructive pulmonary disease (COPD) and commonly referred to as "heaves"
Term
Risk factors for enterolith formation in horses include decreased daily access to pasture grasses and a diet high in which type of hay?
Definition
Alfalfa (due to high protein content)
Term
Which drug is commonly used for treating cows that have follicular cysts?
Definition
Gonadotropin releasing hormone (GnRH), which causes release of FHS and LH fromt he anterior pituitary
Term
Which statement is false regarding Brucella abortus infection? A)Infected horses can develop fistulous withers B) Uterine infection occurs during the second trimester C)Bison and elk are considered a reservoir D)It is highly prevalent in North American cattle
Definition
D) is false. Bovine brucellosis has been nearly eradicated in North America.
Term
What are the 2 known definitive hosts for Neospora caninum?
Definition
Coyote and dog
Term
Within how many hours of birth should a neonatal foal be able to stand?
Definition
Within 2 hours
Term
Atrophy of which laryngeal muscle leads to laryngeal hemiplegia in the horse?
Definition
Cricoarytenoideus dorsalis, innervated by the recurrent laryngeal nerve
Term
What is the most common skin tumor of horses?
Definition
Equine sarcoid
Term
Which heritable muscle disease of quarter horses is characterized by episodes of muscular fasciculations and weakness?
Definition
Hyperkalemic periodic paralysis (HYPP)
Term
What is the most likely direction of a femoral head dislocation in a cow?
Definition
Craniodorsal
Term
Bog spavin is the common term for chronic distension of which joint?
Definition
Tibiotarsal (joint capsule of the hock) - causing a swelling of the dorsomedial aspect of the hock joint
Term
Which coccidian parasite is associated with post-weaning diarrhea in 5-6 week-old piglets?
Definition
Isospora suis
Term
Which statement is false regarding equine viral arteritis? A)It is an RNA virus. B)Mortality is high. C)Standardbreds are particularly susceptible. D)It is diagnosed by virus isolation or serology.
Definition
B)Mortality is high.
Term
In layperson's terms, congenital erythropoietic porphyria in calves is known as: (The name is also helpful in making this diagnosis)
Definition
Pink tooth
Term
A newborn foal is considered premature if it is delivered prior to which gestation age?
Definition
320 days
Term
The most common testicular neoplasm in the aged stallion is: A)teratoma, B)sertoli cell carcinoma, C)seminoma, D)interstitial cell carcinoma
Definition
C)seminoma
Term
In the mare, the embryo is mobile during early pregnancy. The embyro becomes fixed (implanted) by day: !)16-17, B)12-14, C)8-10, D)5-7
Definition
A)16-17
Term
The expected rate of growth for an ovarian follicle in the mare is: A)11-12 mm/day, B)8-9 mm/day, C)6-8 mm/day, D)3-5 mm/day
Definition
D)3-5 mm/day
Term
What is meant by "drying off" a cow, and when is it done?
Definition
Cessation of milk production, at least several weeks prior to parturition. Thus, milking cows typically are pregnant but not lactating for 2 months prepartum, lactating but not pregnant for 2 months postpartum, and both pregnant and lactating for the rest of the year.
Term
What is the minimal gestational age for viability in sheep?
Definition
138 days
Term
What is the adverse effect associated with a cow's consumption of Ponderosa pine tree needles in the last trimester of pregnancy?
Definition
Abortion
Term
Which parasite can cause respiratory distress in cattle, similar to bacterial infections such as those caused by Pasteurella multocida and Mannheimia haemolytica?
Definition
Dictyocaulus viviparus
Term
Which telltale medication history often preceeds the diagnosis of right dorsal colitis in horses?
Definition
NSAIDS, especially Phenylbutazone
Term
Ingestion of which toxic plant can cause arthrogryposis in foals?
Definition
Locoweed (also possibly hybrid Sudan pasture)
Term
Which body systems are affected in horses with white snakeroot poisoning?
Definition
Mainly skeletal and cardiac muscle, which explains the muscle tremors, weakness, choke, and cardiac arrhythmias observed clinically.
Term
A pregnant cow's calf is dead in utero and you are about to perform a fetotomy. Which additional piece of equipment do you need: Krey hook, Gigli saw/wire, wire introducer, wire handles, threader and brush, and disposables (gloves, lubes, etc).
Definition
You need a fetotome, through which to run the saw wire safely inside the cow
Term
Deficiency in which trace mineral is best known for causing muscle weakness and dysphagia in crias?
Definition
Selenium
Term
Is stringhalt an excessive flexion or an excessive extension of the limbs in a horse? Forelimbs or hindlimbs?
Definition
Flexion, hindlimbs. The hallmark sign is spasmodic myoclonus, most pronounced when the horse is made to walk backwards.
Term
Which disorder of sheep is commonly caused by Dichelobacter (formerly Bacteroides) nodosus and is treated topically with copper sulfate?
Definition
Footrot (pododermatitis)
Term
If trephination of the maxillary sinus in a horse exceeds the dorsal boundary for this procedure, which important structure can be lacerated?
Definition
The nasolacrimal duct
Term
Name the 3 site for venipuncture in an awake pig.
Definition
Pinna (convex surface, near lateral border: lateral auricular vein), jugular groove (internal jugular, external jugular, and/or brachiocephalic veins), and orbital venous sinus
Term
In a cow with mastitis, the mammary lymph nodes may be enlarged. Where are these nodes located?
Definition
Dorsal to the udder, between the medial and lateral laminae of the suspensory apparatus of the udder and cranial to the thick, fat-filled connective tissue in the perineum below the ischial arch.
Term
A herd of pigs shows acute thirst, constipation, and sporadic seizures, characteristically beginning with a sitting position and progressing to opisthotonus. Histologically, there ais cerebral polioencephalomalacia. What is the most likely cause?
Definition
"Salt poisoning" (actually, water deprivation causing hypernatremia; true ingestion of excessive salt causing vomiting and diarrhea)
Term
What is the etiologic agent of equine protozoal myelitis (EPM)?
Definition
Sarcocystis neurona (+/- rarely Neospora hughesii)
Term
Hematuria after exercise in the horse is most likely cause by:
Definition
Cystic calculi (urolithiasis)
Term
Bacterial pneumonia in adult horses is most commonly associated with which organism?
Definition
Streptococcus equi zooepidemicus
Term
A 3-month old foal is presented in respiratory distress, with a WBC of 23,500 cells/ul and a fibrinogen of 600 mg/dl. What is the most likely etiology in this case?
Definition
Rhodococcus equi pneumonia
Term
Normal foals consume approximately what percentage of their body weight in milk per day?
Definition
20-27%
Term
Which infectious disease of cattle typically can occur after contact with wildebeest or sheep? What is the causative agent?
Definition
Malignant catarrhal fever (MCF); alcelaphine herpesvirus type 1 (AlHV-1, African strain), ovine herpesvirus type 2 (OvHV-2, sheep isolate
Term
At a hobby farm, a cows and 2 sheep have a 2-day history of sever pruritis and self-trauma. On exam: weakness, recumency, hypersalivarion. These animals have been exposed to feral pigs. What is the most likely diagnosis?
Definition
Aujeszky's disease (pseudorabies)
Term
What is the name of the nasal bot of sheep?
Definition
Oestrus ovis
Term
In a sheep with chronic copper toxicosis, massive release of copper from the liver can trigger which life-threatening event?
Definition
Sever, acute intravascular hemolysis
Term
In horses, which endocrinopathy is associated with hirsutism due to failure of seasonal haircoat shedding?
Definition
Pituitary pars intermdia dysfunction (e.g., adenoma)
Term
This disease of sheep and goats is seen in Africa, India, and the Middle East. Characteristic signs include purulent ocular discharge and erosive stomatitis.
Definition
Peste des pestits reminants
Term
You are living in the mid-Atlantic region of the US and are presented with a six year old Quarter Horse gelding with acute, severe diarrhea, depression and high fever in August. What is the primary initial rule-out?
Definition
Neorickettsia risticii infection (Potomac horse fever)
Term
Which antimicrobial drug is most commonly used for treatment of suspected anaerobic bacterial involvement in horses with pleuropneumonia?
Definition
Metronidazole
Term
What is the causative agent of equine strangles?
Definition
Streptococcus equi subspecies equi
Term
Which horse breed is best known for having a gentic defect leading to severe combined immunodeficiency (SCID)?
Definition
Arabian
Term
What is the retinal pattern of the equine fundus?
Definition
Paurangiotic. That is, it has blood vessels that radiate only a short distance from the optic disk.
Term
Which 2 coccidia species are responsible for hemorrhagic diarrhea in cattle?
Definition
Eimeria bovis and Eimeria zuernii
Term
Bovine trichomoniasis is caused by which organism?
Definition
Tritrichomonas feotus
Term
What is the causative agent of blackleg?
Definition
Clostridium chauvoei
Term
In horses, laryngeal hemiplegia/roaring typically is an idiopathic condition affecting which nerve on which side?
Definition
Left recurrent laryngeal nerve. It is longer than the right and thus thought to be more prone to damage.
Term
Differential diagnoses for vesicles on the lips, nostrils, and coronary bands of pigs consist of which 4 disease?
Definition
Foot and mouth disease (FMD), swine vesicular disease (SVD), vesicular exanthema (VE), and vesicular stomatitis (VS)
Term
What is omphalophlebitis, and how is it best prevented in calves?
Definition
Infection of the umbilical veins (usually ascending). Prevention mainly requires optimal hygiene and sanitation (e.g., clean bedding) at the time of birth; application of such antiseptics as chlorhexidine to the umbilicus may also be beneficial
Term
Which drug can cause unwanted (and potentially long-lasting) penile prolapse int he horse? What is the synonym for penile prolapse?
Definition
Acepromazine; paraphimosis
Term
Which additive in a cow's diet alters rumen metabolism and improved feed efficiency, but can cause cardiotoxicosis in horses?
Definition
Ionophores (e.g., monensin)
Term
Which disease in cattle is thought to be related to Crohn's disease (a chronic enteropathy in humans)
Definition
Johne's disease (Mycobacterium paratuberculosis infection, which produces a granulomatous enteritis similar to Crohn's disease)
Term
The most common ovarian neoplasm in the mare is: A)cystadenoma, B)dysgerminoma, C)granulosa tecal cell tumor, D)teratoma
Definition
C)granulosa thecal cell tumor
Term
Which of the following is a commercially available leutenizing hormone agonist that can be used for hastening ovulation in the mare? A)altrenogest, B)epineprhine, C)follicle stimulating hormone (FSH), D)humane chorionic gonadotropin (HCG)
Definition
D)human chorionic gonadotropin (HCG)
Term
Pneumovagina in the mare is associated with chronic inflammation and infection of the reproductive tract. It is associated with: A)the long vaginal tract in large mares, B)a wide pelvis, C)excessive body condition, D)poor perineal conformation
Definition
D)poor perineal conformation
Term
A viral disease of mice which can result in late gestation pregnancy loss and disease in nursing piglets in swine herds is: A)encephalomyocarditis virus, B)Japanese B encephalitis virus, C)porcine parvovirus, D)porcine rubulovirus
Definition
A)encephalomyocarditis virus
Term
Pigs in modern, intensive, produciton units are weaned at approximately which age: A)3 weeks (range 3-4 weeks), B)4 weeks (range 4-5 weeks), C)5 weeks (range 5-6 weeks), D) 6 weeks (range 6-7 weeks)?
Definition
A)3 weeks (range 3-4 weeks)
Term
In horses, which body system is affected in cases of Arabian fading syndrome?
Definition
The integument. It is an idiopathic, acquired loss of pigmentation of the skin, or vitiligo (the name refers to fading color, not loss of stamina).
Term
Pasteruziation requires heating milk to 161oF (71.7oC) to kill this ubiquitous zoonotic organism, which also causes neurologic disease when it infects cattle and sheep.
Definition
Listeria monocytogenes
Term
What is the most common cause of abomasal impaction?
Definition
Poor quality/coarse roughage as the sole feed (typically used in overwintering beef cows)
Term
What is a common cause of ataxia and proprioceptive deficits in horses that can be found worldwide?
Definition
Cervical vertebral stenotic myelopathy ("Wobbler syndrome")(CSM)
Term
Match the species of Brucella to the principal host: abortus, melitensis, suis; pig, cow, sheep. Only 1 does not also infect bison. Which one?
Definition
B. abortus: cow. Be melitensis: sheep. B suis: pig. B. melitensis does not infect bison.
Term
What causes transmissible gastroenteritis (TGE) in pigs?
Definition
Coronavirus
Term
You are presnted with a depressed, two day-old colt; bloodwork reveals profound azotemia, hyponatremia, and hyperkalemia. What is the primary rule-out?
Definition
Uroperitoneum secondary to urinary bladder rupture; this can occur during parturition or as a result of excessive handling of the foal, especially if the foal is lifted from under the abdomen, which should be avoided
Term
What is the treatment for ketosis in dairy cattle?
Definition
Parentral glucose administration; oral propylene glycol; possibly insulin; possilby corticosteroids
Term
What is the etiology of equine motor neuron disease?
Definition
Vitamin E deficiency
Term
Name 2 species of mites that can infect horses.
Definition
Sarcoptes scabei, Chorioptes equi, Psorptes equi, Pyemotes tritici
Term
Lymphoma associated with bovine leukemia virus occurs most often in which of the following age groups: a)<6 months; B)1-2 years; C)>5 years
Definition
c)>5 years
Term
What are the porential outcomes of toxoplasmosis in a pregnant ewe?
Definition
Embryonic death & resorption, fetal death & mummification, abortion, stillbirth, and neonatal death (~SMEDI)
Term
What is the name of the condition in which a calf has female external gentalia but male gonads and reproductive tract?
Definition
Male pseudohermaphrodism. A true hermaphrodite has both male and female reproductive organs.
Term
What is the major route of transmission for Neospora caninum in cattle?
Definition
Transplacental (vertical) transmission
Term
Infection with Streptococcus equi equi can result in pharyngeal obstruction after abscessation of which lymph nodes?
Definition
Medal and lateral retropharyngeal
Term
What is the common mineral compsition of an equine enterolith?
Definition
Magnesium-ammonium-phosphate cyrstals (struvite)
Term
What is the mean gestation length of the mare?
Definition
340-342 days (based on data in Thoroughbreds; range 325-357 days)
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