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Antiparasitics SG
Her SG
39
Veterinary Medicine
Professional
04/23/2016

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Cards

Term
Which drugs work on invertebrate ligand-gated Cl chh?
Definition
-Macrocyclic Lactones, Fipronil, Afoxalaner (Isoxazolines)
Term
Which drugs work on voltage-gated Na Chh?
Definition
-Pyrethrins/pyrethroids
-indoxacarb
Term
What drugs work as acetylcholinesterase inhibitors? Which is irreversible?
Definition
-Organophosphates & Carbamates
-Organophosphates are irreversible
Term
Which drugs have nicotinic/acetylchline receptor actions?
Definition
-neonicotinoids, pyrantel, levamisole, piperazine
Term
Which durgs are insect development/growth inhibitors?
Definition
-Methoprene, Lufenurone, Pyriproxyfen
Term
Which drug is an arsenical?
Definition
-Melarsomine
Term
Which drugs are beta tubulin polymerazation inhibitors?
Definition
-Benzimidazoles
Term
How do we treat juvenile fleas?
Definition
-Methoprene, Lufenuron, or Pyriproxyfen
Term
How do we treat adult fleas?
Definition
-Fipronil, Imidocloprid, Afoxalaner, Pyrethrin/Pyrethroids, Organophosphates, Carbamates, Nitenpyram, Spinosad, Indoxacarb, some Macrocyclic lactones
Term
How do we treat mites?
Definition
-Macrocyclic lactones, amitraz, lime sulfur
Term
How do we treat lice?
Definition
-macrocyclic lactones, Fipronil, Imidacloprid, Dinotefuran, Organophsophates, Carbamates
Term
How do we treat flies?
Definition
-Pyrethrin/Pyrethroids, Organophosphates, Macrocyclic lactones
Term
How do we treat ticks?
Definition
-Fipronil, Amitraz, Afoxalaner, Pyrethrins/Pyrethroids, Organophosphates, Carbamates, some Macrocyclic lactones
Term
Which drugs are endectocides?
Definition
-Macrocyclic lactones
Term
How do we treat adult heartworms?
Definition
-melarsomine
Term
How do we treat L3, L4 heartworms?
Definition
-Ivermectin, Selamectin, Milbemycin, Moxidectin
Term
How do we treat nematodes?
Definition
-Macrocyclic lactones, Fenbendazole, Pyrantel, Emodepside, Levamisole, Piperazine
Term
How do we treat juvenile flukes?
Definition
-Clorsulon
Term
How do we treat adult flukes?
Definition
-albendazole, clorsulon
Term
How do we treat cestodes?
Definition
-Praziquantel, Epsiprantel, Benzimidazoles, Pyrantel
Term
What do we use for prophylaxiz of coccidia?
Definition
-Decoquinate, Amprolium, Ionophores
Term
How do we treat clinical coccidiosis?
Definition
-Amprolium, sulfonamides, Diclazuril, Ponazuril
Term
How do we treat EPM?
Definition
-Pyremethamine + sulfadiazine, Ponazuril, Diclazuril
Term
How do we treat giardiasis?
Definition
-Fenbendazole, metronidazole
Term
How do we treat Babesia and Theileria?
Definition
-Imidocarb
Term
What are the primary adverse effects we expect to see with macrocyclic lactones?
Definition
-mydriasis, ataxia, CNS depression
Term
What are the primary adverse effects we expect to see with Indoxacarb?
Definition
-wide TI: locak skin reactions
Term
What are the primary adverse effects we expect to see with pyrethroids?
Definition
-CNS signs: tremors, depression, seizures
Term
What are the primary adverse effects we expect to see with anti-acetylchoniesterases (organophosphates & carbamates)? How do we treat?
Definition
-SLUDD
-treat Organophosphate toxicity with 2-PAM and atropine & treat carbamate toxicity with atropine only
Term
What are the primary adverse effects we expect to see with Amitraz?
Definition
-CNS depression
Term
What are the primary adverse effects we expect to see with Imidocarb?
Definition
-nephrotoxicity
Term
What are the primary adverse effects we expect to see with Tetracyclines?
Definition
-nephrotoicity and GI toxicity
Term
What are the primary adverse effects we expect to see with Melarsomine?
Definition
-thromboembolism and arsenical (antidote available), injection site reactions, resp distress, lethargy, ataxia, death
Term
What are the primary adverse effects we expect to see with Benzimidazoles?
Definition
-wide TI: teratogenic (albendazole) and ehpatotoxic
Term
What are the primary adverse effects we expect to see with Nicotinic Rc (Neonicotinoids, Pyrantel, Levamisole, Piperazine)?
Definition
-wide TI: ataxia, nicotinic effects possible
Term
What are the primary adverse effects we expect to see with Spinosad?
Definition
-potential drug interactions with spinosad = ivemermectin = lower seizure threshold
Term
What are the primary adverse effects we expect to see with Praziquantel/epsiprantel?
Definition
-wide TI: GI signs possible
Term
What are the primary adverse effects we expect to see with Fipronil and afoxalaner?
Definition
-none really, wide TI
Term
What are the primary adverse effects we expect to see with Insect Growth Regulators (Methoprene, Lufenuron, Pyriproxyfen)?
Definition
-none really, wide TI
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