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AnChap3
Cells
41
Anatomy
Undergraduate 3
10/01/2011

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Term
Ribosomes
Definition
no membrane; structural support and enzyme activity to amino acids to form protein; rough ER (protein synthesis); smooth ER (lipid synthesis)
Term
Golgi apparatus
Definition
stack of flattened, membranous sacs; modifies, packages, and delivers proteins
Term
Vesicles
Definition
membranous sacs; store substances; transport material around cell
Term
Mitochondria
Definition
membranous sacs w/ inner partitions; ATP generated
Term
Lysosomes
Definition
garbage enzyme-containing sacs; digest worn out cell parts or unwanted substances
Term
Centrosome
Definition
Two rod-like centrioles; produce cilia and flagella; distributes chromosomes during cell division
Term
Cilia
Definition
short hair-like projections; propel substances on cell surface
Term
Flagellum
Definition
Long tail-like projection; provides mobility to sperm
Term
Microfilaments/microtubules
Definition
thin rods and tubules; support cytoplasm; allows for movement of organelles
Term
Nucleolus
Definition
Dense collection of RNA and proteins; site of ribosome production
Term
Chromatin
Definition
Fibers of DNA and proteins; stores info for synthesis of proteins
Term
Cell membrane
Definition
composed of phospholipids, proteins, carbs, other lipids
transport in/out of cell
small, uncharged particles pass through
selectively permeable
cholesterol stabilizes membrane
Term
Proteins
Definition
receptors, pores, channels and carriers, enzymes (chemical reactions can occur) CAMS (cell adhesion molecules) self-markers
Term
Passive process
Definition
no cell energy; simple diffusion; O, CO2 and lipid-soluble substances (Ions go through protein, phospholipids too charged)
facilitated diffusion, osmosis, filtration
Term
simple/facilitated diffusion
Definition
movement of substance from regions high to low concentration; diffusion across membrane w/ help of a channel or carrier molecule, glucose/amino acid (protein may change shape to become carrier pore)
Term
Filtration
Definition
movement of water through selectively permeable membrane from high to low; water follows salt
Term
Osmosis
Definition
Water moves towards solutions of greater osmotic pressure; isotonic same osmotic pressure
Term
Hypertonic
Definition
makes cell shrink; higher osmotic pressure
Term
Hypotonic
Definition
make cell burst; lower osmotic pressure
Term
Active process
Definition
require cell energy; endocytosis, exocytosis, transcytosis; move across gradient; carrier molecules transport from low to high; sugars, amino acids, sodium ions
Term
Sodium-Potassium pump
Definition
active transport; balance by "pumping" 3 Na+ OUT and 2 K+ INTO cell
Term
Endocytosis
Definition
Cell engulfs a substance by forming a vesicle around the substance; includes pinocytosis, phagocytosis, and receptor-mediated endocytosis
Term
Pinocytosis
Definition
part of endocytosis; substance is mostly water; membrane engulfs droplets of liquid from surroundings
Term
Phagocytosis
Definition
part of endocytosis; substance is a solid; membrane engulfs solid particles from surroundings
Term
Receptor-mediated endocytosis
Definition
part of endocytosis; requires substance to bind to a membrane-bound receptor; membrane engulfs selected molecules combines with receptor proteins
Term
Exocytosis
Definition
exiting cell; substances in a vesicle fuse with cell membrane; release of neurotransmitters from nerve cells
Term
Transcytosis
Definition
Combines receptor-mediated endocytosis and exocytosis to ferry particles through a cell
Term
CAMS (cell adhesion molecules)
Definition
Guide cells on move
selectin: allows white cells to "anchor"
Integrin: guides white cells through capillary walls
imp. for growth of embryonic tissue and nerve cells
Term
Chromosomes
Definition
DNA packaged with protein (46-humans)
Term
INTERPHASE (S)ynchronize
Definition
DNA replication (92)
Active; cell grows/maintains routine functions; synthesizes new organelles to prepare for cytoplasmic division
(G) phase: grows/synthesizes structures other than DNA
Term
MITOSIS
Definition
produces two daughter cells from an original somatic cell
Karyokinesis: nucleus divides
Cytokinesis: cytoplasm divides
Phases: prophase, metaphase, anaphase, telophase
Term
PROPHASE
Definition
(1)Chromosomes form; nuclear envelope disappears
Term
METAPHASE
Definition
(2)Chromosomes align midway b/w centrioles
Term
Anaphase
Definition
(3)Chromosomes separate and move to centrioles; begin cytokinesis
Term
Telophase
Definition
(4)chromatin forms; nuclear envelopes form
Term
Cytokinesis
Definition
cell growth check point; anaphase-telophase; contractile ring pinches cytoplasm in half
Term
Tumors
Definition
consequence of loss of cell cycle control
benign: localized
malignant: invasive and cancerous
Term
Gene
Definition
piece of DNA that has code for a specific protein; use to generate RNA then protein
Term
Oncogenes/Tumor suppressor genes
Definition
two major types of genes that cause cancer
oncogenes: activate other genes that increase cell division
TSG: normally regulate mitosis; if inactive they're unable to regulate mitosis; cells known as "immortal"
Term
Stem cell/progenitor
Definition
can divide to form new stem cells or a stem and progenitor cell
Totipotent: rise to every cell
Pluripotent: rise to restricted number of cell types; progenitor is only
Term
Apoptosis
Definition
cell death; happens during cytokinesis
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