Term
protective barrier
regulation of body temp
excretion of salts
vitamin d synthesis
sensory reception |
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Definition
| what skin does for the body |
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Term
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Definition
| keratinized stratified squamous epithelium |
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Term
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Definition
| another name for epithelial cells |
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Term
stratum basale (germinativum)
stratum spinosum
stratum granulosum
stratum lucidum
stratum corneum |
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Definition
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Term
| stratum basale (germinativum) |
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Definition
highest cell proliferation
desmosomes between cells
hemidesmosomes anchor to basal lamina |
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Term
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Definition
spiny appearance due to keratin filament bundles
adjacent cellular processes connect by desmosomes
keratin production
some cell proliferation |
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Term
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Definition
keratinosomes
keratinohyaline granules |
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Term
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Definition
| complex hydrophobic glycophospholipids, released when cells die, bind to keratin filaments and act as cement |
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Term
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Definition
| protein granules interact with keratin and cell membrane |
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Term
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Definition
distinguished as separate layer only thick skin
loss of organelles, cells die |
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Term
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Definition
acellular layer composed of compact keratin
regulates balance btwn cell proliferation and cell shedding
cells in basal layers have high proliferatioin rate and begin to synthesize keratin
cells stop dividing and accumulate keratin as the move up in epidermal layers until they are shed
thick skin vs thin skin
epidermal ridges |
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Term
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Definition
synthesize melanin
transported by microtubles to cell processes
exocytosed from cell processes
endocytosed by keratinocytes in stratum basale and spinosum
keratinocyte lysosomes degrade melanin |
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Term
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Definition
| protects against non-ionizing uv irradiation |
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Term
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Definition
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Term
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Definition
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Term
# of melanin granules synthesized
rates of transfer of melanin to keratinocytes
reaction with lysosomes |
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Definition
| melanin pigmentation depends on what |
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Term
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Definition
| localized benign melanocyte proliferation, can become dysplastic |
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Term
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Definition
radial growth has better prognosis than vertical growth into deeper skin levels
initial spread to regional lymph nodes, then blood stream |
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Term
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Definition
located in all layers of epidermis
dendritic processes extend btwn keratinocytes
act as antigen-presenting cells
facilitate uptake of microbial fragments |
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Term
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Definition
| form synapses on peripheral nerves, believed to fxn as tactile receptors |
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Term
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Definition
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Term
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Definition
| makes up papillary layer of dermis |
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Term
| dense irregular CT with elastic fibers |
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Definition
| makes up reticular layer of dermis |
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Term
| superficial and deep vascular plexi |
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Definition
| play role in thermoregulation |
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Term
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Definition
| arteriovenous anastomoses located in the dermis |
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Term
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Definition
| another term for hypodermis |
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Term
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Definition
looser CT
adipose
movement of skin over underlying structures |
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Term
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Definition
| accessory structure derived from epidermis |
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Term
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Definition
| produces hair shaft and internal root sheath |
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Term
hair bulb
dermal papilla
hair shaft
root sheaths
CT sheath |
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Definition
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Term
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Definition
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Term
| follicle and sebaceous gland |
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Definition
| outermost CT sheath encloses what |
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Term
| sebaceous glands (holocrine) |
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Definition
ducts open into hair follicle
complex lipid secretion
low production until puberty |
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Term
| merocrine (eccrine) and apocrine |
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Definition
| components of sweat glands |
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Term
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Definition
over most of the body
water secretion with NaCl and K |
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Term
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Definition
perineum, anus, axilla
viscous secretion triggered by external stimulus |
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Term
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Definition
| two modified apocrine glands |
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Term
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Definition
free nerve endings in epidermis
merkel cells
meissner's corpuscle (tactile)
paccinian corpuscle (pressure) |
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Term
| meissner's corpuscle (tactile) |
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Definition
| encapsulated in papillary layer of dermis |
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Term
| paccinian corpuscle (pressure) |
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Definition
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Term
collagen fibers thicken
decreased collagen synthesis
collagen fibers begin to cross-link
elastic fiber synthesis decreases |
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Definition
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Term
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Definition
| thickening of corneum and stratum granulosum |
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Term
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Definition
| cells of corneum retain nuclei, normally occurs in oral cavity, may occur with some skin conditions |
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Term
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Definition
abnormal epidermal thickening, usually stratum spinosum
rete pegs
associated with chronic inflammatory conditions |
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Term
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Definition
| epidermal extensions into papillary later are abnormally long |
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Term
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Definition
| inflammation of the skin, can be acute or chronic |
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Term
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Definition
| inflammatory condition, thought to be allergic |
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Term
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Definition
chronic inflammatory condition caused by excessive proliferation of keratinocytes and accelereated upward cellular migration
characterized by acanthosis and erythematous scaly white lesions
perateratosis with microabcesses in epidermis
inflammation and angiogenesis in dermis |
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Term
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Definition
invades dermis but rarely metastasizes
most frequent in areas exposed to sunlight |
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Term
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Definition
| tumors well demarcated and highly keratinized |
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