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Anatomy Chapter 3: foundations tissue and early embryology
2013 Emily
105
Anatomy
Undergraduate 1
01/20/2013

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Term
Identify the four primary tissue types
Definition
There are 4 primary tissue types: epithelial tissue; connective tissue; muscle tissue and neural tissue
Term
Four characteristics of epithelia?
Definition
Characteristics of epithelia include cellularity, polarity, attachment, avascularity and regeneration
Term
What are two specializations of epithelial cells?
Definition
Specializations of epithelial cells include production of secretions, movement of fluids over the surface and movement of fluids through the epithelium itself.
Term
You look at a tissue under the microscope and see a simple squamous epithelium. Can this be a sample of surface skin?
Definition
No a simple squamous epithelium does not provide enough protection against infection, abrasion and dehydration, and is not found on the skin surface
Term
Why is the epithelium regeneration a necessity in a gland that releases its product by holocrine secretion. What occurs in this mode of secretion?
Definition
In holocrine secretion, the entire gland cell is destroyed during the secretory process. Further secretion by the gland requires regeneration of cells to replace those lost during secretion.
Term
Ceruminous glans of the external acoustic meatus of the ear release their products by apocrine secretion. What occurs in this mode of secretion?
Definition
During apocrine secretion, the secretory product and the apical portion of the cell cytoplasm are shed
Term
What functions are associated with a simple columnar epithelium
Definition
A simple epithelium provides protection and may be involved in both absorption and secretion
Term
Identify the three basic components of all connective tissues?
Definition
The three basic components of connective tissue are specialized cells, extracellular protein fibers, and a fluid called ground substances
Term
What is a major difference between connective tissue proper and spporting connective tissue?
Definition
Connective tissue proper refers to connective tissue with many types of cells and extracellular fibers in syrupy ground substance. Supporting connective tissues (cartilage and bone) have a less diverse cell polulation and a matrix that contains closely packed fibers. The matrix is either gel-like (Cartilage) or calcified (Bone)
Term
What are the 2 general classes of cells in connective tissue proper? What cells are found in each class?
Definition
The two types of cells in connective tissue proper are fixed cells and wandering cells. Fixed cells include fibroblasts, fibrocytes, fixed macrophages, adipocytes, mesenchymal cells, and sometimes melanocytes. Wandering cells include free macrophages, mast cells, lymphocytes, plasmocytes, eosinnnophils and neutrophils.
Term
Lack of Vitamin C in the diet interferes with the ability of fibroblasts to produce collagen. What effect might this limited ability to produce collagen have on connective tissue?
Definition
Collagen fibers add strength to connective tissue. We would expect Vitamin C deficiencey to result in the production of connective tissue that is weaker and more prone to damage.
Term
What type of membrane lines passageways of the respiratory and digestive system? Why is this type of membrane suited to these areas?
Definition
Mucous membrane line passageways that communicate with the exterior. They form a barrier that resists the entry of pathogens they must remain moist at all times.
Term
Provide another name for the superficial fascia What does it do?
Definition
ANother name for the superfical fascia is subcutaneous layer or hypodermis. It seperates the skin from underlying tissues and organs. It provides insulation and padding and lets the skin or underlying structures move independently
Term
You are asked to locate the pericardium.. What type of membrance is this and where would you find it?
Definition
The pericardium is a serous membrane that lines the pericardial cavity that covers the heart.
Term
What are the functions of the cutaneous membrane?
Definition
The cutaneous membrane of the skin covers the surface of the body. It consists of a statified squamaous epithelium and an underlying layer of areolar tissue reinforced by a layer of dense connective tissue.
Term
What type of muscle tissue has small, tapering cells with single nuclei and no obvious striations?
Definition
smooth muscle
Term
Why is skeletal muscle called striated voluntary muscle?
Definition
skeletal muscle cells have a banded or striated appearance because of the organization of actin and myosin filaments within the cells
Term
Which tissue is specialized for the conduction of electrical impulses from one body region to another.
Definition
neural tissue
Term
Match the numbered item with the most closely related lettered item.
1. skeletal muscle
2. mast cell
3. avascular
4. transitional
5. globlet cell

a. urinary bladder
b.striated
c. unicellular, exocrine gland
d. wandering cell
e. all epithelia
Definition
1. skeletal muscle = b. striated
2. mast cell = d. wandering cell
3. avascular = e. all epithelia
4. transitional = a. urinary bladder
5. globlet cell = c. unicellular, exocrine gland
Term
Match the numbered item with the most closely related lettered item.

1. collagen
2. cartilage
3. simple epithelium
4. ground substance
5. holocrine secretion

a. connective tissue component
b. tendon
c. single cell layer
d. cell destroyed
e. lacunae
Definition
1. collagen = b.tendon
2. cartilage = e. lacunae
3. simple epithelium = c. single cell layer
4. ground substance = a. connective tissue component
5. holocrine secretion = d. cell destroyed
Term
Epithelial cells do:
Definition
- cover every exposed surface of the body
-line the digestive, respiratory, reproductive and urinary tracts
-line internal cavities and passageways
Term
What is the dense connective tissue that forms the capsules that suround many organs?
Definition
deep fascia
Term
the reduction of friction between the parietal and visceral surfaces of an internal cavity is the function of ?
Definition
Serous membranes
Term
Characteristic of epithelial cells?
Definition
-consists of single or multiple cell layer.
- They always have a free surface exposed to the external enviroment or some inner chamber or passageway.
- They are avascular
Term
Functions of connective tissue include:
Definition
-establishing structural framework for the body
-transporting fluids and dissolved materials
- storing energy reserves
Term
Property of smooth muscle tissue
Definition
- is composed of small cells with tapering ends
- can replace cells and regenerate after a injury
- contracts with or witout nervous stimulation
Term
Tissue changes with age include?
Definition
-decrease ability to repair
-less efficient tissue maintenance
- thinner epithelia
Term
What type of supporting tissue is found in the pinna of the ear and the tip of the nose?
Definition
elastic cartilage
Term
An epithelium is connected to underlying connective tissue by?
Definition
a basal lamina
Term
Name the wandering cells found in connective tissue proper?
Definition
eosinophils, neutrophils, and mast cells
Term
How does the role of a tissue in the body differ from that of a single cell?
Definition
A single cell is the unit of structure and function, whereas groups of cells work together as units called tissues
Term
A layer of glcoproteins and a network of fine filaments that perform limited functions together act as a barrier that restrict the movement of proteins and other large molecules from the connective tissue to epithelium. this describes rhe structure and function of ?
Definition
the reticular lamina
Term
Connective tissue cells that respond to injury or infection by dividing to produce daughter cells that differentiate into other cell types are?
Definition
mesenchymal cells
Term
How does a tendon function?
Definition
A tendon is made of cords of dense regular connective tissue that attaches a skeletal muscle to a bone. The collagen fibers run along the long axis of the tendon and transfer the pull of the contracting muscle to the bone.
Term
what is the difference between exocrine and endocrine secretions?
Definition
Exocrine secretions occur in ducts that lead onto surfaces, enocrine secretions occur in intersitical fluid and then into the blood vessels.
Term
What is the significance of the cilia on the respiratory epithelium?
Definition
The presence of cilia at the surface of the epithelium means that the mucous layer, which rest on the epithelium surface, will be kept moving and the respiratory surface will bekept clean.
Term
Why does pinching the skin usually not distort or damage the underlying muscle?
Definition
The skin is seperated from the muscles by a layer of loose connective tissue. The loose connective tissue provides padding and elastic properties that permit a considerable amount of independent movement of the two layers.
Term
How does a tendon differ from an aponeurosis?
Definition
While a tendon is made of cords of dense regular connective tissue, an aponeurosis is made of a sheet or ribbon of connective that resembles a flat tendon. Aponeuroses may cover the surface of muscles an assist superfical muscles in attaching to one another or to other stucture.
Term
What are germinative cells and what is their function?
Definition
Germinative cells are stem cells usually found in the deepest layer of epithelium. They divide to replace cells lost or destroyed at the epithelial surface.
Term
Primary function of connective tissue?
Definition
fill internal spaces
provide structure support
-store energy
Term
Primary function of muscle tissue?
Definition
contracts to produce active movement
Term
Primary function neural tissue
Definition
conducts electrical impulses

carries information
Term
function of epitheial tissue?
Definition
Physical protection, controls permeability, provide sensation produces secretions
Term
microvilli-
Definition
increase the surface area of the cell. Found a lot in cells specialized for absorption and secretion
Term
Sterocilia
Definition
Are long microvilli. found in male reproductive tract and inner ear.
Term
Cilia
Definition
Beat in a coordination fashion and move substance along the surface of the epithelial cell. Found in the respiratory tract.
Term
Name the epithelial tissue layers
Definition
simple or stratified
Term
Name the cell shape of the epithelial tissue
Definition
Sauamous, cuboidal or columnar,
Term
Epithelial tissue
Special cases (name) where?
Definition
Transitional and pseudostratified columnar
*Line the respiratory system and hollow conducting organs organs of the urinary system (bladder)
Term
Stratified Squamous epithelium

Location

Function
Definition
Location: surface of the skin;ining of the throat, mouth, esophagus, rectum, anus and vagina

Functions: Provide physicial protection against abrasion, pathogens, and chemical attack
Term
Simple Cuboidal epithelium
Location?
Function?
Definition
Location: glands, ducts, portion of kidney tubules, thyroid gland

Functions: limited protection, secretion and absorption
Term
stratified cuboidal epithelium
Location?
Function?
Definition
Location : Lining some ducts (rare)
Function: Secretion, protection and absorption
Term
Simple Columnar epithelium
Location
Function
Definition
Location: lining of stomach, intestine, gallbladder, uterine tubes and collecting ducts of kidney

function: protection, secretion and absorption
Term
Stratified Columnar epithelium:
Location
function
Definition
Location: small areas of pharynx, epiglottis, anus, mammary gland, salvary gland ducts, and urethra

Function : protection
Term
Pseudostratified Ciliated Columnar Epithelium

Location:

Function:
Definition
Location: Lining of Nasal cavity; trachea and bronchi and portions of the male reproductive track

Functions: Protection and secretion
Term
Transitional Epithelium
Location
Function
Definition
Locations: urinary bladder; renal pelvis and ureters

Functions: permits expansion and recoil after stretching
Term
Secretory Sheets
Function
Location
Definition
Function: are secreted onto an epithelial surface and travel through a duct.
Location: Found in stomach and secretes acids and enzymes
Term
Mixed Endorcine gland
Example: and produces
Definition
Mixed exocrine gland. Example is submandibular salivary gland
produces both serous (water and enzyme) and mucus secretions
Term
Name 3 types of protein fibers
Definition
Collagen
Elastic
Reticular
Term
Collagen fibers (Describe)
Definition
are tough and resistant to pulling forces. They are long, straight and unbranced and often occur in bundles
Term
elastic fibers (describe)
Definition
are smaller and freely branch. Can be stretched to 150% of their relaxed length
Term
reticular fibers (describe)
Definition
form branching networks
Term
Describe ground substance
Definition
colorless and has no specific shape.
supports cells and provides a medium through which substances are exchanged.
can range from a fluid-like consistency (plasma of blood) to solid (as in bone)
Term
List 2 specialized cells and describe
Definition
Fixed cells- are stationary and are involved in the maintenance repair and energy storage.

Wandering cells are mobilized during infection or injury
Term
List the fixed cells
Definition
Fibroblast
fibrocytes
fixed macrophages
adipocytes
mesenchymal cells
melanocytes
Term
List the wandering cells
Definition
free macrophages
mast cells
lymphocytes
neutrophils and esinophils
Term
fibroblasts
Definition
fixed cells-produces connective tissue fibers
Term
fibrocytes
Definition
fixed cells- maintain connective tissue fibers and matrix
Term
fixed macrophages
Definition
fixed cells-phagocytize pathogens and damaged cells
Term
adipocytes
Definition
fixed cells- store lipid reserves
Term
mesenchymal cells
Definition
fixed cells- connective tissue stem cells that can differeniate into other cell types
Term
melanocytes
Definition
fixed cells- synthesize melanin
Term
free macrophages
Definition
wandering cells-mobile/traveling phagocytic cells-(derived from monocytes of the blood)
Term
mast cells
Definition
wandering cell- stimulate local inflammation
Term
lymphocytes
Definition
wandering cells-participate in immune response
Term
neutrophils and eosinophils
Definition
wandering cells -small phagocytic blood cells that mobilize during infection or tissue injury
Term
Name the three types of loose connective tissue?
Definition
1. Areolar tissue
2. Adipose tissue
3. reticular tissue
Term
Areolar tissue
Location
and Function
Definition
Locations: within and deep to the dermis of skin, and covered by epithelial linings of the digestive, respiratory, and urinary tracts between muscles, around blood vessels, nerves, and around joints.

Functions: cushions organs, provides support but permits independent movement; phagocytic cells provide defense against pathogens
Term
Adipose tissue

Location:

Function:
Definition
Adipose tissue
location: deep into the skin, especially ar sides, buttocks, breast, padding around eyes and kidney

Functions: provides padding and cushion shocks; insulates (reduces heat loss) stores energy
Term
Reticular tissue:
Location
Functions
Definition
Locations: liver, kidney, spleen, lymph nodes and bone marrow

functions: provides supporting framework
Term
Dense connective tissue- Name three types
Definition
1. Dense regular connective tissue
2. Elastic tissue
3.Dense irregular connective tissue
Term
Dense regular connective Tissue

Location

Functions
Definition
location: Between skeletal muscles and skeleton ; between bones or stabilizing positions of internal organs (ligaments) covering skeletal muscles; deep fasciae

Functions: provide firm attachment; conducts pull of muscles; reduces friction between muscles; stabilizes relative positions of bones
Term
Elastic tissue

Location and funtion
Definition
Elastic tissue:
Locations: between vertebrae of the spinal column; ligaments supporting the penis; ligaments supporting transitional epithelia in blood vessel walls
Functions: stabilizes positions of vertebrae and penis; cushions shocks, permits expansion and contraction of organs
Term
Dense irregular connective tissue
Location and functions
Definition
locations: capsules of visceral organs; periostea and perichondria; nerve and muscle sheaths; dermis

Functions: Provides strength to resist forces applied from many directions; help prevent overexpansion of organs such as the bladder.
Term
Fluid Connective tissue
(includes blood and lymph)

List
Definition
Red blood cells
White blood cells (monocyte, lymphocytes, eosinophil, neutrophil, basophil)
platelets
Term
Supporting connective tissue (cartilage)List the 3
Definition
1. Hyaline cartilage
2. elastic cartilage
3. Fibrous cartilage
Term
Hyaline cartilage:

location and function
Definition
Location: between tips of ribs and bones of sternum; covering bone surfaces at synovial joints; supporting larynx (voice box) trachea and bronchi; forming part of nasal septum

functions: provides stiff but somewhat flexible support, reduces friction between bony surfaces
Term
Elastic cartilage:

Location

Function
Definition
Location: auricle of external ear; epiglolottis; auditory canal; cuneiform cartilages of larynx

functions: provides support, but tolerates distortion without damage and returns to orginal shape.
Term
Fibrous cartilage
location:
Functions:
Definition
Location: pads within knee joint; between public bones of pelvis; intervertebral dics

Funtion: resists compression; prevents bone-tobone contact; limits relative movement
Term
supporting connective tissue
Definition
Bone
Term
membranes -a combination of epithelial and connective tissue what are the 4 types
Definition
1. mucous membrane
2. serous membrane
3. cutaneous
4. synovial
Term
mucous membrane
describe and location
Definition
lines body cavities that open directly to the exterior

the type of epithelial tissue depends on the location (ex: digestive system- simple columnar; respiratory system: pseudostratified columnar)
Term
Serous Membrane (serosa)
Definition
mesothelium secretes serous fluid that lubricates the layers and reduces friction.
lines body cavities that do not open to the exterior (parietal layer) and covers organs in the cavitiy (visceral cavity)
Term
list the clinical conditions that can effect the serous membrane linings.
Definition
Pleurisy, Pericarditis, peritonitis, ascites
Term
cutaneous membrane (skin)

Describe
Definition
includes the epidermis and dermis

varies in thickness in different parts of the body
Term
synovial membrane
describe
Definition
lines the cavities of freely moveable joints; incomplete epithelial layer and secretes synovial fluid
Term
Connective Tissue Functions
Definition
-Provides strength and stability
-Maintains relative positions of internal organs
-provides route for distribution of blood vessels, lymph and nerves
Term
Connective Tissue Components:
Definition
superfical fascia/subcutaneous layer/hypodermis
deep fascia
suberous fascia
Term
superficial fascia-connective tissue framwork
Definition
Between skin and underlying organs

areolar tissue and adipose tissue

also known as subcutaneous layer or hypodermis
Term
connective tissue framework deep fascia
Definition
forms strong, fibrous internal framework

dense connective tissue
bound to capsules, tendons and ligaments
Term
connective tissue framework- subserous fascia
Definition
located between serous membranes and deep fascia
areolar tissue
Term
List the three muscle tissues:
Definition
1. skeletal
2. Cardiac
3. Smooth
Term
Describe skeletal muscle tissue
Location and funtion
Definition
skeletal muscle- cells are long, cylindrical striated and multinucleate

Location: Combined with connective tissues and neural tissue in skeletal muscles

Function: Moves or stabilizes the position of the skeleton; guards entrance and exits to the digestive, respiratory, and urinary tracts; generates heat, protects internal organs
Term
Cardiac muscle tissue

Describe:
Location:
Funtions
Definition
celles are short, branched, and striated, usually with single nucleus; cells are interconnected by intercalated discs
Location: Heart
Functions circulate blood; maintains blood pressure
Term
Smooth muscle tissue:
Describe
Locations
Functions
Definition
Cells are short, spindle-shaped, and nonstriated with a single, centeral nucleus
Location: found in walls of blood vessels and in digestive, respiratory, urinary and reproductive organs
functions: moves food, urine, and reproductive tract secretions; controls diameter of respiratory passageways; regulates diameter of blood vessels
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