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Unit 4.1 - Cardiovascular Function & Control
BMS235 Quiz 4
49
Veterinary Medicine
Undergraduate 1
04/03/2018

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Term
absolute refractory period (ARP)
Definition
the time during which the cardiac cell cannot depolarize regardless of the strength of the stimulus
Term
acetylcholine
Definition
a neurotransmitter that slows down the rate of the heart by decreasing SA node automaticity
Term
alpha 1 (α1) receptors
Definition
receptors located on peripheral vasculature (skin, subcutaneous tissue, mucous membranes), GI tract, kidneys, etc.; causes arteriolar vasoconstriction when stimulated
Term
alpha 2 (α2) receptors
Definition
receptors located on the pre-synapatic terminal of the neuron that releases norepinephrine; when stimulated by the release of norepinephrine (or drugs that mimic norepinephrine), these receptors shut down further release of norepinephrine, providing a sedative effect on the animal
Term
aorta
Definition
the main artery of the body that carries oxygenated blood away from the heart and into systemic circulation
Term
aortic valve
Definition
the semilunar valve that lies between the left ventricle and the aorta; controls the flow of blood from the left ventricle out to the body (systemic circulation)
Term
arrhythmia
Definition
abnormal rhythm of the heart caused by disrupted electrical activity
Term
atrial-ventricular node (AV node)
Definition
receives the wave of depolarization from the SA node to depolarize the ventricles
Term
automaticity
Definition
the ability of a cell to depolarize spontaneously
Term
beta 1 (β1) receptors
Definition
receptors located on the SA node, AV node, and cardiac muscle; increase heart rate and force of contraction
Term
beta 2 (β2) receptors
Definition
receptors located on the bronchioles of the lungs and blood vessels of the skeletal muscles; causes bronchodilation and vasodilation to assist in fight or flight
Term
bundle of His
Definition
the pacemaker of the ventricles when the depolarization wave from the SA node can't reach the ventricles
Term
bundle branches
Definition
Term
cholinergic blockers
Definition
drugs that block acetylcholine receptors and increase heart rate
Term
cholinergic receptors
Definition
receptors that bind to acetylcholine to slow the rate of the heart by slowing conduction of the depolarization wave from atria to ventricles
Term
congestive heart failure
Definition
weak cardiac muscles
Term
depolarization
Definition
occurs by sodium channels opening to allow an influx of sodium ions across the cell membrane of polarized cells; this removes the charged "poles" of the cell membrane
Term
efflux
Definition
the movement of ions out of a cell
Term
fast sodium channels
Definition
allow sodium ions to quickly influx by following their concentration gradient
Term
fibrillation
Definition
an arrhythmia that occurs when the chambers of the heart are not contracting in a coordinated manner
Term
influx
Definition
the movement of ions into a cell
Term
left atrium
Definition
the chamber of the heart that receives oxygenated blood from the lungs (pulmonary circulation)
Term
left ventricle
Definition
the chamber of the heart that pumps oxygenated blood out to the body (systemic circulation)
Term
mitral valve
Definition
the left atrioventricular (AV) valve that lies between the left atrium and left ventricle and has 2 cusps (bicuspid)
Term
narrow therapeutic index
Definition
the effective concentrations of a drug are very close to concentrations that produce toxicity
Term
P wave
Definition
represents depolarization of the atria on an ECG
Term
parasympathetic nervous system (PSNS)
Definition
the component of the autonomic nervous system that regulates functions related to rest and restoration
Term
phase 0
Definition
rapid sodium influx via fast channels, interior of the cell is very positively charged
Term
phase 1
Definition
potassium channels open, interior of cell becomes less positive/more negatively charged
Term
phase 2
Definition
influx of calcium ions keeps the charge on the interior cell membrane more positive despite potassium leaving the cell
Term
phase 3
Definition
calcium channels close while potassium ions continue to efflux out of the cell
Term
phase 4
Definition
resting phase, base line; the cell will remain in this phase until stimulated again
Term
pulmonic (pulmonary) valve
Definition
a semilunar valve that lies between the right ventricle and the pulmonary artery; controls the flow of deoxygenated blood to the lungs for reoxygenation
Term
Purkinje fibers
Definition
Term
QRS complex
Definition
large wave on an ECG that represents depolarization of the ventricles
Term
relative refractory period
Definition
the time during which the cardiac cell may depolarize if sufficient stimulus is provided
Term
repolarization
Definition
occurs when sodium channels shut and potassim channels open, allowing potassium ions out of the cell and re-establishing poles across the cell membrane
Term
right atrium
Definition
the chamber of the heart where deoxygenated blood returns from the body (systemic circulation)
Term
right ventricle
Definition
the chamber of the heart that pumps deoxygenated blood to the lungs (pulmonary circulation) for reoxygenation
Term
sinoatrial node (SA node)
Definition
known as the "pacemaker" of the heart because it depolarizes spontaneously and more frequently that any other cell in the heart
Term
sodium-potassium-ATPase pump
Definition
the enzyme responsible for pumping sodium ions out of the cell and potassium ions into the cell
Term
sympathetic nervous system
Definition
the component of the autonomic nervous system that regulates functions related to fight or flight
Term
T wave
Definition
represents ventricular repolarization on an ECG
Term
tricuspid valve
Definition
the right atrioventricular (AV) valve that lies between the right atrium and right ventricle and has three cusps
Term
vena cava
Definition
large veins that carry deoxygenated blood from the body into the right atrium of the heart
Term
wave of depolarization
Definition
an influx of sodium ions that causes adjacent sodium channels to also open up in a wave along the cell
Term
PR segment
Definition
the flat period on an ECG that represents the delay between the depolarization of the atria and the depolarization of the ventricles; occurs when the depolarization wave is passing through the AV node to get to the ventricles
Term
beta blockers
Definition
drugs that block beta receptors to decrease heart rate
Term
adrenergic receptors
Definition
receptors that bind to norepinephrine or epinephrine to increase heart rate and speed up conduction of the depolarization wave from atria to ventricles; also stimulates cardiac muscles to contract with greater force
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