Recombinant
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Single Crossover
One point of crossover occurs between the selected point on the parent organism
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NCO
No Crossover occurs between the selected points on the parent organism strings
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Double Crossover
Two-point crossover where two points to be selected on the parent organism strings. Everything between the two points is swapped between the parent organisms, rendering two child organisms:
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Coefficient of coincidence
Ratio of observed double crossovers to expected crossovers
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Interference
Degree to which one crossover interferes with additional crossovers
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Mapping function
A function to relate the map distance to the recombination rate. Also takes into consideration that some multiple crossovers will be undetected. Takes into account all crossovers.
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Quantitative trait
Some measurement such as height, weight, yield (not eye color or ordinal numbers like number of bristles)
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Heritability
Proportion of phenotypic variation due to genetic differences
0 = no genetic variability
1 = no environmental variablilty
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Broad Sense Heritablity
Proportion of the phenotyic variance that can be attributed to genetic variance
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Narrow Sense Heritability
Proportion of the phenotypic variance that can be attributed to additive genetic variance
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Mass selection
Also truncation selection. A type of selection where we are interested in increasing some quantitative trait through selective breeding
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Selection Differential (SD)
The selection differential is the difference of the base population mean and the mean of the selected parents.
I x Sigma
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Selection Response (SR)
Difference in mean of original vs mean of offspring
H2SD
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Genotypic Array
Set of genomic frequencies
PAA+QAa+Raa
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Gametic Array
Set of allelic frequencies
pA+qa
p=P+1/2Q, q=R+1/2Q
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Homozygosity
Organism that possesses two identical alleles at a locus
-In regards to Hardy-Weinberg: Fraction of homozygotes in the population
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Heterozygosity
Organism that possesses two different alleles at a locus
-In regards to Hardy-Weinberg: Fraction of heterozygotes in the population
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Polymorphism
having multiple alleles of a gene within a population, usually expressing different phenotypes
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Hardy-Weinberg equilibrium
Important principle of population genetics stating that, in a large, randomly mating population not affected by mutation, migration, or natural selection, allelic frequencies will not change and genotype frequencies stabilize after one generation the proportion is p2, 2pq, q2, where p equals the frequency of allele A and q equals the frequency of allele a.
p2AA+2pqAa+p2aa
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Directional Selection
Selection in which one trait or allele is favored over another. Favored allele is eventually fixed in the population and the other is lost.
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Balancing Selection
All alleles remain in population but heterozygous fitness is greatest
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Dispersive Selection
Fitness of heterozygote is smaller than either of the homozygotes
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Overdominance
Selection in which the heterozygote has higher fitness than than of either homozygote; also called heterozygote advantage
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Underdominance
Selection in which the heterozygote has lower fitness than that of either homozygote
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Mean Fitness
The sum of the fitnesses of the genotypes of a population weighted by their proportions; hence a weighted mean fitness.
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Genetic Drift (Random Drift)
Change in allelic frequency due to sampling error
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Founder Population
Small population colonizing a new area.
-Small size
-Not representative of entire population
-Undergo Strong Selection
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Ploidy
is the number of complete sets of chromosomes in a biological cell.
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Euploidy
True copy number. Refers to mutations that involve excess or deficiency of all all all of the chromosome types
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Aneuploidy
Derived from a nondisjunction event within a single species. Normally infertile and have an odd number of copies of haploid number
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Nondisjunction
Failure of homologous chromosomes or sister chromatids to separate in meiosis or mitosis
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Autoreplication
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Duplication
Adding portions of the chromosome
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Deletion
Mutation in which one or more nucleotides are deleted from a DNA sequence
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Inversion
When the order of the DNA is rearranged form normal order on the chromosome
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Partial Monosomy
Monosomy refers to lack of one chromosome of the normal complement. Partial monosomy can occur in unbalanced translocations or deletions, in which only a portion of the chromosome is present in a single copy
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Partial Trisomy
Trisomy refers to the presence of three copies, instead of the normal two
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Autoploidy
Derived from a nondisjunction event within single species. Excess or deficiency in single chromosome
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Allopolyploidy
Having two or more complete sets of chromosomes derived from different species.
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Translocation
Movement of a chromosome segment to a nonhomologous chromosome or to a region within the same chromosome; also movement of a ribosome along mRNA in the course of translation
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Transposition
Movement of a transposable genetic element from one site to another. Replicative transposition increases the number of copies of the transposable element; nonreplicative transposition does not increase the number of copies
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Fusion
Where 2 chromosomes come together
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Fission
Where 2 Chromosomes split
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Behavior
Reaction of an organism to environmental stimuli
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Chemotaxis
is the phenomenon in which bodily cells, bacteria, and other single-cell or multicellular organisms direct their movements according to certain chemicals in their environment.
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Phototaxis
occurs when a whole organism moves in response to the stimulus light.
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Environmental Bias
Example: Fish in streams inevitably face upstream
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Concordance
Percentage of twin pairs in which both twins have a particular trait
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Twin studies
Allows scientists to study human differences based on environment and genetics when they have itentical (monozygotic twins)genetics or are raised in same environment but have similar genes (monozygotic)
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Single gene behavioral traits
behavioral traits the are the result of single genes
Examples: Lesch-Nyhan Disease, Fragile X, Hygienic Bees
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Threshold trait
A trait that falls into natural groups that originate not in categorically distinct causes but in whether or not the outcome attains critical values; e.g., gallstones may result from a categorical cause or from unusual levels of causal factors that themselves show no evidence of grouping.
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comparative studies
studying breeds/species with extreme traits often helps us to understand behavioral traits
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Plasticity
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Selection Intensity
Variable in Mass selection equations (I)
Given for proportion
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Standardized Selection Point
Value in Mass selection equations (Z)
Given for proportion
Z=(x-mu)/sigma
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Mean
Mu
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Standard Deviation
Sigma
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Proportion selected
p
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Assortative Mating
When mates are chosen based on the similarity of their phenotypes. Results in an increase in homozygosity
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Pericentric Inversion
Includes centrosome