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ZOO4232-EXAM 1
Parasitology Exam 1 Notes
279
Microbiology
Undergraduate 4
09/29/2013

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Term
Since Pathogenic Parasites rely on their hosts for survival, the population dynamics of the parasite are influenced by the population dynamics of the hosts. The host population will likely contain which of the following?
Definition
a. individuals who are susceptible
b. individuals who are infected
c. individuals who have been infected but have never recovered
*d. all of the above
Term
While an {_______} lives mainly on the surface of its host, an {________} lives mainly in the body of its host.
Definition
ectoparasite, endoparasite
Term
What constitutes an epidemic?
Definition
a. 25 outbreaks
b. 50 outbreaks
c. 1 outbreak
d. 10 outbreaks
*e. all of the above
Term
Elevated levels of which immune cells indicate a worm infection?
Definition
a. basophils
b. eosinophils
Term
A disease involving a parasite that has accidentally infected a human; the normal host for the parasite is an animal.
Definition
*a. zoonosis
Term
Hemoflagellates are transmitted by which organisms?
Definition
*B) Insects
Term
The family Trypanosomatidae, contain two genera that parasitize humans, which are Genus Leishmania and Genus Trypanosoma.
Definition
True
Term
Which is not a form of transformation that is undergone by Leishmania?
Definition
*B. Use of amino acids as a nitrogen source
Term
Leishmania parasites enter cells by {__________}.
Definition
phagocytosis
Term
Of the three developmental stages in ticks, which stage is the most significant in human infection?
Definition
*b. nymph
Term
Which one of these is NOT a natural host resistance to Plasmodium infections?
Definition
*e. Fructose-6-phosphate deficiency
Term
The cysts of Balantidium coli have cilia.
Definition
True
Term
Giardia lambilia replicates via a process called longitudinal binary fission.
Definition
True
Term
Vector(s) of Chagas disease include which of the following. (HINT: Recognize the difference between a vector and the actual parasite which causes the disease)
Definition
b. Triatoma infestans
c. Rhodnius prolixus
*d. B and C
Term
In Kinetoplastids RNA editing is the process of postranscriptional sequence alteration via {_______} or {_____} of uridylate residues at specific sites of Mitochondrial RNA.
Definition
Insertion / Deletion
Term
Acute Chagas disease is mostly found in:
Definition
*a. children under 10
Term
What is the main downfall to using a blood smear to diagnose a T.cruzi infection?
Definition
*b. Can only find parasites in blood during acute phases of disease
Term
Trypanosoma cruzi is found only in
Definition
*b. the Americas
Term
Which of the following is true of Trypanosoma cruzi?
Definition
*d. The vector is the Reduviid bug
Term
The West Nile Virus only infects the human species.
Definition
False
Term
[_____] is the vector responsible for "sleeping sickness."
Definition
*b. Tsetse fly
Term
Mucosal Leishmaniasis are primary lesions of the mucous memebranes such as the nose and oral cavity
Definition
False
Term
All of the following are differences between slender and stumpy trypomastigotes, except
Definition
*d. cytoskeleton composition
Term
T. cruzi is the causative agent of {______} disease
Definition
Chagas / Trypanosomiasis
Term
T. cruzi parasites are ONLY found in the Americas--if a person is infected with them, they can't have acquired it from any other place in the world.
Definition
True
Term
In the fourth morphological form among hemoflagellates, many types of polymorphism are exhibited. These are
Definition
a. long, slender trypomastigote
b. stumpy trypomastigote
*d. a & b
Term
In Plasmodium, the asexual phase [_____], occurs in the human, whereas the sexual phase [______], occurs in the mosquito
Definition
*b. schizogony;gamogony
Term
Which of the following parasitic stages is characterized by asexual division?
Definition
*d. Schizont
Term
Which alteration of the vagina will help treat T. vaginalis?
Definition
*a. Lowering the pH to 4.5
Term
The metronidazole drug used to treat T. vaginalis forms an intermediate that is toxic, damaging DNA and other macromolecules.
Definition
True
Term
How would one describe the parasites of T. vaginalis when observed in a wet mount?
Definition
*d. Very active
Term
What structure in Trichomonas resemble the mitochondria?
Definition
*c. Hydrogenosome
Term
How does T. vaginalis change the pH of the vagina?
Definition
*b. It makes it more alkaline
Term
Infection of T. vaginalis in women is seen less if:
Definition
*b. They use oral contraceptives
Term
Men are assymptomatic carriers of Trichomonas vaginalis.
Definition
True
Term
The trophozoites of Trichomonas species are very active and motile.
Definition
True
Term
Dientamoeba fragilis is not invasive.
Definition
True
Term
Giardia produces an IgA [____]
Definition
*b. Protease
Term
Giardia lamblia infection is commonly seen in:
Definition
a. Children 6-10 years of age
b. Daycare centers
c. Homosexual males
d. Wilderness campers
*e. All of the above
Term
What gives the feces of individuals infected with Giardia lamblia its distinctive smell?
Definition
*c. The layer of fat present
Term
If you let feces of an individual with Giardia lamblia settle, a layer of fat will become apparent.
Definition
True
Term
Maturing cysts in Giardia lamblia gain:
Definition
*b. two more nuclei
Term
Cysts are the site of nuclear division in Giardia lamblia.
Definition
True
Term
The entire life span of the four species of Plasmodium that infect humans is spent in two hosts: the female mosquito insect vector and a human host.
Definition
True
Term
This complex of organelles are found in the sporozoite and merozoite stages of the life cycles of these organisms
Definition
*b. apical complex
Term
Babesiosis, toxoplasmosis, cryptosporidiosis, isosporiasis and cyclosporidiosis belong to the phylum Apicomplexa.
Definition
True
Term
The "eyes" in Giardia lamblia are its [_____].
Definition
*a. Nuclei
Term
A fool-proof way to detect infection by an amoeba is through the discovery of cysts in feces.
Definition
False
Term
[______] results in intermittend watery diarrhea with stools containing mucus and blood.
Definition
*c. Balantidial dysentery
Term
Which of the following are human reservoirs of Balantidium coli?
Definition
a. Pigs
c. Monkeys
*e. A and C
Term
The cysts of Balantidium coli have cilia.
Definition
True
Term
Balantidium coli undergoes sexual reproduction by [______]
Definition
Conjugation
Term
Balantidium coli undergoes sexual reproduction by [_____]
Definition
Conjugation
Term
[_____] is associated with contamination of contact lens fluid.
Definition
*a. Acanthamoeba keratitis
Term
Naegleria fowleri produce sucker-like appendages or [_____] that 'nibble' away at the tissue culture cells.
Definition
*a. amebostomes
Term
High prevalence of antibodies to Naegleria is found in [_____]
Definition
*a. young adults in southeastern USA
Term
Both trophozoites and cysts are found in Acanthamoeba species.
Definition
True
Term
Both trophozoites and cysts are found in Naegleria fowleri.
Definition
False
Term
Free-living amoebas are intestinal blood parasites.
Definition
False
Term
The American form of trypanosomiasis is caused by Trypanosoma vivax.
Definition
False
Term
Fluctuations in the number of Trypanosoma brucei gambiense is widely attributed to its ability to vary the chemical composition of its [_____]
Definition
*a. variant surface glycoproteins (VSGs)
Term
The infective morophological form of the protozoan Trypanosoma in humans is the______.
Definition
*b. metacyclic trypomastigote
Term
In humans, the initial sign of cutaneous leishmaniasis infection is______.
Definition
*c. vascularized papule
Term
When the identification of intracellular amastigotes from blood and tissue smears are inconclusive, xenodiagnosis can be used but is often time consuming.
Definition
True
Term
In a leishmaniasis infection, replacement of infected cells produces hyperplasia and consequent enlargement of visceral organs associated with the system, such as the [______] and [______]
Definition
*a. spleen and liver
Term
Which of the following are the three clinical manifestations of Leishmania in humans?
Definition
*b. visceral, cutaneous, mucocutaneous
Term
The causative agent for visceral leishmaniasis, also known as dumdum fever, or kala-azar, is:
Definition
*c. Leishmania donovani
Term
Leishmaniasis is considered an opportunistic infection and is grouped among those diseases that take advantage of immunocompromised individuals.
Definition
True
Term
Each of the following statements concerning Trichomonas vaginalis is correct except:
Definition
*d. T. vaginalis causes dysentry
Term
In RNA editing in kinetoplastids,what does TUTase stand for?
Definition
*b. 3'terminal uridylyl transferase
Term
Visceral Leishmaniasis mainly infects the elderly people of Europe.
Definition
False
Term
What is the correct taxonomy of the parasite T. cruzi from phylum to genus?
Definition
*b. Sarcomastigophora, Mastigophora, Kinestoplastida, Trypanosomatidae, Trypanosoma
Term
What organelle in the cytoplasm of Protozoa is used mainly for osmoregulation?
Definition
*b. Contractile Vacuole
Term
What is the main function of IgE?
Definition
*b. triggering histamine release from mast cells
Term
All of the following are characteristics of hemoflagellates except:
Definition
*c. numerous mitochondria
Term
The most important question to ask during the differential diagnosis of an infection from T. brucei is:
Definition
*b. Has the patient been to east or west Africa
Term
The vector for T. brucei brucei, T. brucei gambiense, and T. brucei rhodesiense is:
Definition
*c. tsetse fly
Term
What do xenodiagnosis studies show?
Definition
*a. There is communication between parasites and vectors that recruit parasites to feeding vectors
Term
The cell-funeral hypothesis explains how:
Definition
*d. T. cruzi infection results in host T cells killing other host cells
Term
One of the most significant presentations of Chagas disease, caused by T. cruzi, is:
Definition
*a. heart complications
Term
T.cruzi demonstrates intracellular pathogenesis through lysosome-mediated entry of an infected cell.
Definition
True
Term
Hemoflagellates have cyst forms.
Definition
False
Term
How do the trypomastigote, epimastigote, promastigote, and amastigote forms differ regarding the overall morphology of the hemoflagellates?
Definition
*c. location of kinetoplast relative to nucleus and the single flagellum
Term
Along with a kinetoplast, hemoflagellates also have:
Definition
*c. glycosomes
Term
What is the difference between the Stercoraria and Salivaria subgenuses of the genus Trypanosoma of the Hemoflagellates?
Definition
*a. location of where the parasite develops in the vector
Term
The tissue inflammatory response during amoebiasis is initiated and fueled by a combination of human and amoebic factors and ultimately leads to basophil-mediated intestinal destruction.
Definition
False
Term
Which is true about free living amoeba Naegleira fowleri:
Definition
*a. There is no cyst stage in humans
Term
Metronidazole is effective against:
Definition
a. worms
b. anaerobes
c. Giardia
*d. all of the above
Term
You're attempting to identify a sample of unknown bacteria. You've been told it belongs to the genus Entamoeba, but you still need to determine the species. Looking under a microscope, you see jagged chromosomal bars and nuclei predominately located around the outside. Based on this information, what is this bacteria?
Definition
*c. E. coli
Term
In regards to Plasmodium falciparum, once the parasite gets into red blood cells and is dividing, what is the duration of the fever free period?
Definition
*c. 36-72 hours
Term
Which of the following is pathogenic under the Sub-order Tubulina?
Definition
*b. Entamoeba
Term
Metronidazole is a typical drug used to treat visceral protozoa.
Definition
True
Term
Which of the following is a mode of transmission for amoeba?
Definition
a. water
b. food-borne
*d. a and b
Term
Primary amoebic meningoencephalitis (PAM) due to Naegleria fowleri, if diagnosed in time, can be treated with the following:
Definition
*c. intravenous and intrathecal amphotericin B and miconazole, plus rifampin
Term
An effective way to reduce specific visceral protozoal infection such as E. hystolytica and G. lamblia is to:
Definition
*b. Boil drinking water, add 1.25-3 grams of iodine per liter of water in endemic areas
Term
Which of the following is not a symptom of Intestinal Disease (Amebic Colitis)?
Definition
*d. weight gain
Term
Ciliates are found in which Phylum?
Definition
*a. Ciliophora
Term
Ciliates have which kinds of vacuoles?
Definition
a. contractile
c. food
*d. a and c
Term
Naegleria fowleri "nibble" away at cells by means of sucker-like appendages called {________}
Definition
amebostomes
Term
Cysts can be killed by:
Definition
*b. boiling
Term
Ionophore-like proteins called {_______} mediate cytolytic and apoptotic effects among epithelial cells and neutrophils.
Definition
amoebapores
Term
Amoeba-induced inflammations in the intestine leads to {_______}-mediated intestinal destruction.
Definition
neutrophil
Term
Immobile parasites can invade the intestine.
Definition
False
Term
Amebic Liver abscess, induced by Trophozoites, is:
Definition
*c. destruction of liver cells
Term
The mucosa of the intestines gets thinner with Amebic Colitis.
Definition
False
Term
Hallmarks of intestinal disease (amebic colitis) include:
Definition
a. flask shaped lesions
b. diarrhea, dysentery, GI pain
*d. a and b
Term
Pentatrichomonas hominis
Definition
a. have 5 free flagellar
b. reside in the large intestine
c. are thought to be associated with bowel disease
*d. all of the above
Term
Trichomonas tenax have 4 free flagellar
Definition
True
Term
Backpacker's disease is the popular name of the infection caused by:
Definition
*b. Giardia
Term
Giardia lambia divides by binary fission in the {_________} direction.
Definition
longitudinal
Term
Amoebaphore A in Entamoeba histolytica trophozoites cause liver abscesses whereas amoebaphores B and C are the causative agents of amoebic colitis.
Definition
True
Term
All of the following are nonpathogenic flagellates except:
Definition
*b. Trichomonas vaginalis
Term
Giardia has no mitochondria but can use oxygen when available.
Definition
True
Term
Amoebaphore A in Entamoeba histolytica trophozoites cause liver abscesses whereas amoebaphores B and C are the causative agents of amoebic colitis.
Definition
True
Term
In which morphological form of Entamoeba histolytica is the organism considered pathogenic?
Definition
*a. Trophozoite
Term
What are the end products in the metabolization of lactate in Trichomonads?
Definition
a. Formate
b. Acetate
*d. a and b
Term
The carrier state of amoebiasis is known as:
Definition
*d. Luminal amoebiasis
Term
Species in the genus of Trichomonas do not have cysts.
Definition
True
Term
Which of the following species causes malabsorption of fats, fat soluble substances and Vitamin B12?
Definition
*a. Giardia
Term
Which of the following statements is false?
Definition
*d. Tsetse flies lay their eggs in the shallow water, making it easy to find and eliminate their eggs.
Term
Which type of cyst from some amoebae parasites, found in humans and domestic animals, contains chromatoidal bars?
Definition
*d. E. coli
Term
Many protozoa form cysts which are round cytoplasmic masses surrounded by a rigid or semi-rigid cyst wall secreted by an organism. Which of the following is not true of cysts?
Definition
*b. The cyst form of an organism is not the infective form of a parasite.
Term
Biopsy specimens were taken from patients infected with just Naegleria and patients infected with just Acanthamoeba. What is the difference observed between the two different biopsy specimens?
Definition
*d. Both cysts and trophozoites are found in the specimen from patient infected with Acanthamoeba, only trophozoites are found in the specimen from the patient infected with Naegleria, however.
Term
Which of the following is false about primary amebic meningoencephalitis?
Definition
*b. Cysts found in CSF and high neutrophil count.
Term
Which of the following speicies are free living amoebae?
Definition
*a. Naegleria fowleri and Hartmanella
Term
Which of the following is false about Entamoeba gingivalis?
Definition
*a. The mature cyst has the size of 15 um.
Term
The mature cyst of Entamoeba histolytica usually has 8 nuclei.
Definition
False
Term
Which of the following species belong to suborder Tubulina?
Definition
*c. Entamoeba histolytica, Entamoeba gingivalis, Iodamoeba buctschlii
Term
Which of the following species has the biggest size in suborder Tubulina?
Definition
*b. Entamoeba gingivalis
Term
Species in sub-phylum Mastigophora use pseudopodia for locomotion.
Definition
False
Term
Species in sub-phylum Sarcodina use flagella for locomotion.
Definition
False
Term
Genitourinary amebiasis is one of the extraintestinal diseases caused by trophozoite- induced cell destruction.
Definition
True
Term
Which of the following is extraintestinal diseases caused by trophozoites of Entamoeba histolytica?
Definition
a. Amebic liver abscess
b. Pulmonary Amebiasis
c. Brain abscess.
*d. All of the above
Term
The two main functions of Entamoeba histolytica’s mediators of pathogenesis are:
Definition
a. Attachment to host’s epithelia cells in the large intestine, and protection against binding of antibody and attachment
b. Attachment to host’s epithelia cells in the large intestine, and protection against phagocytosis by neutrophils.
c. Attachment to host’s epithelia cells in the large intestine, and protection against phagocytosis by macrophages.
*d. None of the above.
Term
Which of the following is true about Entamoeba histolytica?
Definition
a. It belongs in the class Lobosea
b. It has mitosomes.
*d. a and b are correct
Term
Non-pathogenic amoeba usually have ________ in their trophozoites.
Definition
*b. Bacteria
Term
Which of the following endoparasites is parasite of digestive tract?
Definition
a. Giardia lambia
b. Entamoeba histolytica
c. Balantidium coli
*d. All of the above
Term
Intestinal and Urogential Flagellates are members of the phylum:
Definition
*e. Sarcomastigophora
Term
Giardia requires _______ cysts to establish infection.
Definition
*b. 10-100
Term
{_________} is the fatty and smelly stool often associated with Giardia.
Definition
Steatorrhea
Term
The incubation period of Giardia is {________}.
Definition
1-2 weeks
Term
Which of the following is a similarity between prokaryotes and eukaryotes?
I. Both share an identical genetic language.
II. Both share a common set of membrane-bound organelles. III. Both have plasma membrane of similar construction.
IV. Both share common metabolic pathways.
Definition
*c. I , III and IV
Term
What are some of the symptoms associated with Amebic Colitis?
Definition
a. Gastro-intestinal pain
b. Diarrhea
c. Weight loss
*d. All of the above
Term
About how much of the world’s population is infected with E. histolytica?
Definition
*b. 10%
Term
What is a main characteristic of Entamoeba coli?
Definition
*a. has 8 nuclei
Term
What is a unique feature of Entamoeba histolytica?
Definition
*d. Has central nucleolus
Term
Endodyogeny is a form of endopolyogeny where what is formed?
Definition
*b. Two daughter cells
Term
Many protozoa form cysts.
Definition
True
Term
Which of the following is considered to be the world's most prevalent intestinal parasite?
Definition
*d. Giardia
Term
One way to distinguish between Entomoeba histolytica and Entomoeba coli is by the number of nuclei, the chromatoidal bars, and the size of the cysts.
Definition
True
Term
Which genus is pathogenic out of the suborder Tubulina?
Definition
*c. Entamoeba
Term
What is commonly found inside pathogenic amoebas?
Definition
*c. Erythrocytes
Term
{__________} attracts phagocytes to a pathogen.
Definition
Opsonization
Term
Early and late endosomes are distinguished on the basis of what? (Select all that apply)
Definition
*a. Buoyant density
*c. pH
*d. protein composition
Term
Which of the following is NOT a host type?
Definition
*a. Obligate Host
Term
Which of the following supports the immature (not fully developed) form of a parasite?
Definition
*c. Intermediate host
Term
This cell allows macrophages to engulf foreign particles in the host. {__________}
Definition
Cytoskeleton
Term
Which is true of the genus Trichomonas?
Definition
a. they have free flagella
b. no cyst form
c. anatomically site specific
*d. these are all true
Term
A few components of the innate immune system are macrophages, the lining of internal tracts, secretions, soluble blood proteins, and the skin.
Definition
True
Term
Metronidazole is a drug used to treat facultative aerobes such as Giardia and Entamoeba histolytica.
Definition
False
Term
Which of the following statements is incorrect?
Definition
*b. Cyst is the main form of transmission
Term
Which of the following processes can be further studied to develop anti-protozoan drugs?
Definition
*d. The signaling pathway involves that leads to the biosynthesis of cyst wall components.
Term
What of the following statements is true about protozoa?
Definition
*a. Have encystation that protect it against unfavorable environmental conditions.
Term
Schizogony is a type of protozoa’s sexual reproduction, and sygany is a type of asexual reproduction.
Definition
False
Term
Entamoeba histolytica and Escherichia coli can both have a maximum of 4 nuclei in its cyst form.
Definition
False
Term
In an archeological dig, you find and unknown organism. You dissect the flagellum and find that the microtubules are arranged in a 9+2 structure. Based on this structure you can conclude that this organism...
Definition
*b. is a eukaryote
Term
Which of the following is not a mediator of the pathogenesis of Entamoeba histolytica?
Definition
*d. hard external shell not sensitive to bodily changes
Term
A patient with Amebiasis complains of gastro-intestinal pain and diarrhea. A stool sample taken from this patient will most likely contain...
Definition
*c. Entamoeba histolytica trophozoites
Term
Sasha was diagnosed HIV positive 5 years ago. Upon her recent trip to Cabo San Luca, Mexico she returned with diarrhea, nausea and vomiting and dehydration. She also felt muscle cramps and weakness. Her physician prescribed her medication for Cholera, but the symptoms remained. What parasitic infection best described Sasha’s symptomatology?
Definition
*b. C. parvum
Term
As a general rule among flagellates the principle means of locomotion is flagellar, where as among amoeba it is pseudopodial.
Definition
True
Term
Humans are the definitive host for round worms because humans harbor the reproducing adult roundworms. Depending on the species, the adult female nematode produces either fertilized eggs or Larvae. Which route is incorrect?
Definition
a. Eggs maybe immediately infective by being ingested
b. Eggs or larvae may require a period of external development to reach the infective stage
c. An insect may transmit eggs or larvae to a new host
*d. None of the above
Term
What distinguishes a pathogenic amoeba from a nonpathogenic is the ability to transform from the cyst form to the trophozoite form:
Definition
False
Term
Which of the following is NOT true of Balantidium?
Definition
*d. It is among the smallest members of Protozoa
Term
Which of the following parasites causes African sleeping sickness?
Definition
*b. Trypanosoma brucei
Term
During pairing of homologous chromosomes,crossover of chromosomes may result in the formation of recombinant.
Definition
*C. Chromosomes
Term
Naegleria is commonly found in fresh water lakes in ponds in Florida and the southern U.S.
Definition
True
Term
In ciliates, the numerous basal bodies are interconnected by a series of subpellicular [_______] or neurofibrils.
Definition
*b. microfilaments
Term
Which of the following endoparasites is parasite of digestive tract?
Definition
a. Giardia lamblia
b. Entamoeba histolytica
c. Balantidium coli
*d. All of the above
Term
Which type of pseudopodia is the most common form among parasitic amoebae?
Definition
*b. Lobopodia
Term
[________] 1. Crescent shaped membrane
Definition
Pelta
Term
[________] 2. Rodlike structure that runs along the base of the undulating membrane
Definition
Costa
Term
[________] 3. Supporting structure embedded along the longitudinal axis on the cytoplasm
Definition
Axostyle
Term
Which of the following processes does not involve sexual reproduction?
Definition
*c. Schizogony
Term
Endodyogeny is a specialized sexual reproduction involving nuclear exchange and union after cells join.
Definition
False
Term
Which of the following are true about cysts:
I) They are the infective or transmissible form of parasite.
II) They protect against unfavorable external environmental conditions.
III) They are the site for morphogenesis and nuclear division.
Definition
*d. I, II, and III
Term
Which enzymes are located within dynein arms of an axoneme?
Definition
*a. ATPases
Term
Which of the following protozoans are particularly notorious for causing primary amoebic meningoencephalitis?
Definition
*b. Naegleria fowleri
Term
Why is the fatality rate for those infected with Naegleria fowleri so high?
Definition
a. Death occurs only a few days after symptoms surface
b. Most diagnoses are made post mortem
c. Treatment options are few and provide limited effectiveness
*d. All of the above
Term
During asexual reproduction in Protozoa, the process of fission takes place in which sequence?
Definition
*c. organelles, nucleus, cytoplasm
Term
Members of the sub-phylum Sarcodina have which characteristic?
Definition
*d. usage of pseudopods for locomotion
Term
Members of the phylum Sarcomastigophora have:
Definition
*c. Flagella and/or Pseudopodia
Term
If you encounter an organism that has a macronucleus and a micronucleus, you can tell that you are NOT dealing with a ciliate.
Definition
False
Term
Well-defined nuclei bounded by nuclear envelopes are characteristic of ALL protozoa.
Definition
True
Term
How are microtubules within axoneme of motile flagella/cilia organized?
Definition
*d. 9+2
Term
Balantidium coli is in Phylum {_______}
Definition
Ciliophora
Term
What is the size of Protozoa?
Definition
*b. 1-150 micrometers
Term
What is the purpose of encystation?
Definition
a. protection against unfavorable external environmental conditions
b. nuclear division
c. parasite transmission
*d. all of the above
Term
Organisms in Protozoa are:
Definition
*c. single-celled, eukaryotic
Term
Protozoa can reproduce both sexually and asexually.
Definition
True
Term
Native cells first encounter which of the following cell receptors:
Definition
b. IgM
c. IgD
*d. both b and c
Term
There are five different classes of antibodies distinguished by heavy chains called Isotypes. Which class is associated with hypersensitivity?
Definition
*c. IgE
Term
Antigen-presenting cells that activate helper T cells must express which of the following on their surfaces?
Definition
*C. Class II MHC antigens
Term
What is the portion of antigen that is bound by a given antibody or recognized by T cell defined as?
Definition
*b. Antigenic determinant
Term
Which Immunoglobulin comprises as much as 80% of all antibodies in the blood?
Definition
*a. IgG
Term
Globular proteins are produced by which immune cell type?
Definition
*b. B Cells
Term
Where do T-Cells mature?
Definition
*b. Thymus
Term
During primary and secondary immune responses, the antibody or antibodies involved is/are:
Definition
a. IgM
b. IgA
c. IgG
*d. Two of the above
Term
The response of IgG during a first exposure is exactly the same as it is during a second exposure.
Definition
False
Term
The innate immune response is specific to a microbe.
Definition
False
Term
All the following are true of the adaptive immune response except?
Definition
*b. The magnitude of the response decreases with every encounter
Term
Which of the following are associated with MHC class II?
Definition
a. binding of peptides from molecules that are internalized by cell
b. CD4+ T cells
Term
The HIV virus targets which type of cell as a receptor?
Definition
*b. CD4 T-cells
Term
A deficiency in this immunoglobulin isotype, the major isotype found in the intestinal tract, can lead to higher susceptibility to Giardia infection. Which isotype is it?
Definition
*a. IgA
Term
Which of the following is a similarity between phagocytosis and endocytosis?
Definition
*c. They are both part of the immune system.
Term
According to the clonal selection theory, B cells become committed to antibody formation..
Definition
*b. In the absence of the antigen
Term
Antibodies are specific to their native conformations.
Definition
True
Term
Immunological memory provides long-term immunity.
Definition
True
Term
T cells bind to antigens in their native conformations.
Definition
False
Term
Which Immunoglobulin can form a pentamer?
Definition
*c. IgM
Term
Each antibody has how many equivalent binding sites?
Definition
*b. Two
Term
Regarding adaptive immune response, what increases with each encounter?
Definition
*E. Magnitude of response and Affinity only
Term
Which of the following statements is FALSE regarding B cells?
Definition
*d. B cells commitment to antibody specificity occurs after exposure to the antigen
Term
What is the most prevalent immunoglobulin isotype found in serum (blood)?
Definition
*a. IgG
Term
High levels of eosinophils are often indicative of worms.
Definition
True
Term
Which of the following is NOT a characteristic of Adaptive Immune Response?
Definition
*c. It is not specific to microbe
Term
Most immune cells originate from stem cells found in bone marrow.
Definition
True
Term
Which of the following cytokines is INCORRECTLY paired with its function?
Definition
*b. IL 10; stimulates B-cell differentiation
Term
In a humoral reaction, specialized molecules in the circulatory system interact with the parasite, forming immune complexes.
Definition
True
Term
Insecticides are the most ecological way to control intermediate hosts.
Definition
False
Term
Except certain viral infections, parasitic diseases are more difficult to control than other infectous diseases.
Definition
True
Term
Parasites reproduce fast with a large number of progeny.
Definition
False
Term
Caterpillars are invading a small garden. Certain plants in the garden set off a pheromone. Wasp migrate and kill the caterpillars. What type of interaction is this?
Definition
*b. Tritrophic interaction
Term
A hosts spleen and red blood cells have become enlarged because of a parasite. What type of effect does this parasite have on the host?
Definition
*d. Hypertrophy
Term
Constant cell damage, which causes death of cells or tissues, is an example of:
Definition
*c. Necrosis
Term
Each time our bodies encounter an antigen, there is refinement of the immune response so that next time, our bodies are better at recognizing the invading entity. This is an example of which of the following?
Definition
*a. increasing affinity within the adaptive immune response
Term
Th1 cells characteristically secrete interleukin 2, gamma interferon, and tumor necrosis factor (TNF)
Definition
True
Term
T-cells are activated by which of the following?
Definition
*b. clonal selection
Term
The components of innate immunity in eukaryotic cells include:
Definition
a. secretions
b. linings of internal tracts
c. Phagocytic cells (macrophages, neutrophils. and natural killer cells.
*d. all of the above
Term
Which of the following is NOT true of antibodies?
Definition
*c. Antibodies are produced by both B cells and T cells.
Term
T cells...
Definition
*d. Are unique in that they can only recognize antigens presented to them by another cell (usually a macrophage).
Term
Component proteins are part of cellular innate immunity.
Definition
False
Term
What type of immune cells derived from myeloid progenitor cells is specialized for parasitic infection?
Definition
*d. Eosinophil
Term
One important group of opsonin molecules is complement protein.
Definition
True
Term
The main difference between B cells and T cells mentioned in lecture is that:
Definition
*c. Only B cells secrete their immunoglobulin receptors as plasma antibodies.
Term
Which of the following is not a type of membrane protein?
Definition
*b. cytoskeletal proteins
Term
The main difference between phagocytosis and endocytosis is:
Definition
*d. the participation of actin in phagocytosis
Term
Intermediate filaments is composed of:
Definition
*b. alpha keratins
Term
A cell can respond to a signal by:
Definition
a. activating enzyme activity
b. changing its cytoskeleton
Term
The inner and outer leaflets of the plasma membrane bilayer feature identical lipid profiles.
Definition
False
Term
What are blood-borne factors that can coat particles to be ingested?
Definition
*c. Opsonins
Term
Drugs that limit or restrict worm mobility in the gastrointestinal tract MOST LIKELY involve which of the following cell feature that helps increase the effectiveness of the treatment?
Definition
*b. the worm's cytoskeleton
Term
Lipid-soluble molecules, such as alcohols, cannot diffuse through the plasma membrane.
Definition
False
Term
[___________] proteins are covalently linked to membrane via a lipid molecule.
Definition
Lipid anchored
Term
Which of the following describes the fluid-mosaic model of the plasma membrane?
Definition
*b. phospholipid bilayer with embedded proteins
Term
Which is NOT a part of the eukaryotic cell nucleus?
Definition
*a. Ribosomes
Term
Which of the following is true about phagocytosis (e.g., the endocytic pathway of parasites)?
Definition
*b. Phagocytosis is dependent on microfilaments.
Term
Which of the following is incorrect?
Definition
a. Being diploid allows the parasites to combine its chromosome and generates diversity.
b. The advantage of being diploid is different from the advantage of sexual reproduction in parasites.
*c. All parasites known are diploid.
d. DNA is packaged into chromosomes
Term
Which of the following is not involved in motility of the cell?
Definition
*c. keratin
Term
Which of the following is false regarding commensal microbes?
Definition
a. Antigenic and can elicit antibody responses
b. Synthesize metabolites that are essential nutrients for the host
c. Acquired by infection
*d. All of the above are true
Term
Which characteristic is not true of the plasma membrane?
Definition
*b. It ensures compartmentalization within the cell.
Term
What parasite can survive the harsh conditions of lysosomes fusing to the phagosome in which it is contained and prevent the host from killing it?
Definition
*c. Leishmania
Term
What are the classes of phagocytic receptors?
Definition
*b. opsonin-dependent and non-opsonin dependent
Term
What are the classes of endosomes?
Definition
*a. early and late
Term
Phagocytosis is the process by which:
Definition
*c. specialized cells (macrophages, neutrophils, dendritic cells) internalize particulate material greater than 0.5um in diameter.
Term
All of the following are classifications of membrane proteins in a eukaryotic cell EXCEPT:
Definition
*c. phagocytic
Term
The [________] is the site where synthesized proteins and other materials are sorted, modified and from where they are transported to specific cellular destinations.
Definition
Golgi Apparatus
Term
Which of the following membrane proteins include receptors?
Definition
a. Integral Proteins
c. Lipid Anchored Proteins
Term
What are the functions of the cytoskeleton?
Definition
a. Provide movement of cilia and flagella
b. Transport materials and organelles within the cell
Term
MHC class I and class II are present in all cells, making them antigen presenting cells.
Definition
False
Term
The host-pathogen interaction always results in disease.
Definition
False
Term
[________] Circular RNA with no protein coat
Definition
Viroid
Term
[________] Virus injects genetic information into host cell DNA and becomes a provirus
Definition
Lysogenic Infection
Term
[________] Virus hijacks host cell machinery to replicate itself; kills host cell
Definition
Lytic infection
Term
[________] Is not a living cell
Definition
Virus
Term
Which of the following proteins span the membrane?
Definition
*b. integral proteins
Term
The endoplasmic reticulum performs the following function(s)?
Definition
a. Protein synthesis
b. Lipid synthesis
Term
Some cyanobacteria as well as plants are capable of performing photosynthesis.
Definition
True
Term
The following can be found in both Prokaryotes and Eukaryotes except?
Definition
*c. Nucleus
Term
What is the significance of membranes to host-parasite relations?
Definition
*a. The parasite has to avoid activating the host via membrane proteins
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