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ZOO 3115; Dr. Cherrington, Respiration (04-15)
Study material for UW ZOO 3115, Exam 3
37
Physiology
Undergraduate 3
05/05/2015

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Term
(04-15) In a lung volume and pressure, what is delta P at the beginning of inspiration? (Vander 13.13)
Definition
delta P = 0-0
Term
(04-15) What is the equation for delta P?
Definition
delta P = Palv - Patm
Term
(04-15) In a lung volume and pressure, what is Pip at the beginning of inspiration? (Vander 13.13)
Definition
Pip = -4
Term
(04-15) In a lung volume and pressure, what is the transpulmonary pressure at the beginning of inspiration? (Vander 13.13)
Definition
Transp = 0 - (-4) = +4
Term
(04-15) In a lung volume and pressure, what is delta P in mid inspiration? (Vander 13.13)
Definition
delta P = (-1) - 0 = -1; Air is moving in.
Term
(04-15) In a lung volume and pressure, what is Pip in mid-inspiration? (Vander 13.13)
Definition
-6
Term
(04-15) In a lung volume and pressure, what is transpulmonary pressure in mid inspiration? (Vander 13.13)
Definition
Trans = (-1) - (-6) = 5
Term
(04-15) In a lung volume and pressure, what is delta P at the end of inspiration? (Vander 13.13)
Definition
delta P = 0 - 0 = 0; No airflow
Term
(04-15) In a lung volume and pressure, what is Pip at the end of inspiration? (Vander 13.13)
Definition
Pip = -7
Term
(04-15) In a lung volume and pressure, what is the transpulmonary pressure at the end of inspiration? (Vander 13.13)
Definition
Transp = 0 - (-7) = +7; This is the point of the highest tension
Term
(04-15) In a lung volume and pressure, what is delta P at mid-expiration? (Vander 13.13)
Definition
delta P = 1 - 0 = 1; Airflow is going out
Term
(04-15) In a lung volume and pressure, what is Pip at mid-expiration? (Vander 13.13)
Definition
Pip = -5
Term
(04-15) In a lung volume and pressure, what is the transpulmonary pressure at mid-expiration? (Vander 13.13)
Definition
Transp = 1 - (-5) = +6
Term
(04-15) What is pneumothorax? What is its consequence?
Definition
A puncture of the pleural sac, causing it to equilibrate with air. It results in a collapsed lung.
Term
(04-15) How is pneumothorax treated?
Definition
1) close the outer wound so air can't get into the chest cavity 2) release air trapped in chest cavity 3) seal hole in actual lung
Term
(04-15) Define lung compliance. Why is it important?
Definition
the "stretchiness" of alveoli. this determines how much they respond to pressure difference.
Term
(04-15) Give the formula for lung compliance
Definition
compliance = (delta V) / (delta P); "How much change in volume for a given change in pressure"
Term
(04-15) Between a basketball, a balloon, and a plastic bag, which is the most compliant? What disease does this imitate?
Definition
The plastic bag; similar to emphyzema
Term
(04-15) Between a basketball, a balloon, and a plastic bag, which requires more pressure to get the same volume change?
Definition
Basketball
Term
(04-15) Between a basketball, a balloon, and a plastic bag, which is the "stiff" lung?
Definition
Basketball
Term
(04-15) Between a basketball, a balloon, and a plastic bag, which is a "loose lung"
Definition
Plastic bag
Term
(04-15) Between a basketball, a balloon, and a plastic bag, which would likely have fibrosis or scarring?
Definition
Basketball
Term
(04-15) What does compliance depend on? Which is primary?
Definition
Material properties of the lung, surface tension (primary)
Term
(04-15) Why don't our lungs collapse?
Definition
Intrapleural pressure is negative; lung surfactant secreted by Type II cells reduces surface tension
Term
(04-15) What is the cause of infant respiratory distress syndrome?
Definition
a deficiency in lung surfactant
Term
(04-15) What are the treatments for infant respiratory distress syndrome?
Definition
Cow surfactant used to suplement deficiency; positive-pressure ventilation
Term
(04-15) What is spirometry?
Definition
measuring lung volumes
Term
(04-15) What is the tidal volume of the lungs? (VT)
Definition
Appproximately 500 mL of each breath in and out
Term
(04-15) What is the expiratory reserve volume? (ERV)
Definition
Maximal exhalation after the tidal volume
Term
(04-15) What is inspiratory reserve volume? (IRV)
Definition
the maximal inspiration after tidal volume
Term
(04-15) What is the vital capacity of the lungs? (VT) What is the formula?
Definition
The combination of tidal volume, expiratory reserve volume, and inspiratory reserve volume; VT = Vt + IRV + ERV
Term
(04-15) What is residual volume in the lungs?
Definition
The air left in lungs after maximal expiratory reserve volume
Term
(04-15) What does a vitalograph show? Which factor is on the y-axis/x-axis?
Definition
a measure of exhaled volume in liters (y-axis) vs. time in seconds 9x-axis)
Term
(04-15) On a vitalograph, what is an FVC?
Definition
Forced Vital Capacity
Term
(04-15) On a vitalograph, what is FEV1? What is it a measure of?
Definition
The amount of air blown off in 1 second. This is a measurement of resistance.
Term
(04-15) From a vitalograph, what is the useful formula to discover disease?
Definition
(FEV1 / FVC) (100%)
Term
(04-15) What are the three main obstructive respiratory diseases?
Definition
Asthma (bronchial smooth muscle spasms); bronchitis (excessive mucus production); Cystic fibrosis
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