Term
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Definition
Calmodulin (made up of 4 Ca2+ ions) – it activates adenylate cyclase and phosphodiesterase
Calcium binds to a protein to form Troponin – found in cardiac muscle
Cell communication
Controls endocrine gland secretion
Needed for blood coagulation |
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Term
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Definition
| (made up of 4 Ca2+ ions) – it activates adenylate cyclase and phosphodiesterase |
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Term
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Definition
Part of the cell membrane structure
Energy
Gene Replication |
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Term
| Regulation of Calcium & Phosphate |
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Definition
Parathyroid Hormone
Calcitronin
Vitamin D |
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Term
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Definition
Opposite of PTH
Produced by C-cell of PT gland
Net effect:
↓ Ca2+
↑ Phosphate
Hypercalcemia: stimulates release
Hypocalcemia: inhibits release |
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Term
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Definition
| Stimulates membrane transport of Ca2+ b/t cells |
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Term
| Primary Hyperparathyroidism |
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Definition
| leads to hypercalcemia/hypophosphatemia → hypercalciuria → urolithiasis/nephrocalcinosis (kidney stones) |
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Term
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Definition
rare, genetic
Leads to renal osteodystrophy (ROD)
No renal excretion of phosphate |
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Term
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Definition
rare, genetic, X-linked
Defect in renal absorption of phosphate
↑ excretion of phosphate in urine |
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Term
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Definition
| deficency in PTH caused by infection or parathyroidectomy |
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Term
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Definition
| PTH level is normal or high means that there is a receptor problem |
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Term
| Effect of Hypercalcemia on Calcitronin |
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Definition
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Term
| Effect of Hypocalcemia on Calcitronin |
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Definition
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Term
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Definition
| cannot use because of chelation |
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Term
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Definition
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Term
| Citrate/Lactate and Calcium |
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Definition
can bind to free calcium to make ligands
falsely decreased result for an ionized calcium test
they are ok for total calcium tests |
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Term
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Definition
| favors disassociation of Ca2+ from ligands and proteins |
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Term
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Definition
| favor association of Ca2+ from free Ca2+ to proteins and ligands |
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Term
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Definition
| form Troponin – found in cardiac muscle |
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Term
| Regulation of Calcium & Phosphate |
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Definition
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Definition
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