Term
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Definition
| hemopoietic stem cell undergoes malignant transformation into a primitive, undifferentiated cell with abnormal longevity |
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Term
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Definition
| most common pediatric cancer |
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Term
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Definition
| long lived hematopoietic progenitor cell causes high circulating number of blasts, replacement of normal marrow by malignant cells and the potential for leukemic infiltration of the CNS and abdominal organs |
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Term
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Definition
| this is the 2nd most common death in children less than 15yrs old and has a secondary raise in incidence after age 45 but can occur at any age |
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Term
| CBC and peripheral blood smear 1st then bone marrow examination |
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Definition
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Term
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Definition
| Life threatening disease in which the cells that normally develop into neutrophils, basophils and eosinophils and monocytes become cancerous and rapidly replace normal cells in the bone marrow |
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Term
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Definition
| The most common pediatric cancer |
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Term
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Definition
| anemia, bruising, petechia,epistaxis, bleeding gums or menstrual irregularity,fever of unknown origin, lymphadenopathy, splenomegaly, hepatomegaly |
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Term
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Definition
| Dx with bone marrow exam. tx chemo or stem cell transplantation |
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