cosm / cosmo  

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universe             

~spelling    cosmo  =  cosm + vowel

        cosmic - having to do with the universe
        cosmologist - an expert in the study universe

maniac  

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one who is obsessed

        pyromaniac - one who is obsessed with fire
        theomaniac - one who  is obsessed with a god            

un --  

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not

        unaware - not aware                  

  unclean - not clean

demon / demono    

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=    evil spirits    

~spelling    demono = demon + vowel

        demonologist – an expert in the study of evil spirits
        demonic - having to do with evil spirits

Caution:  Not "demonstrate"   (de + monstr)

therm / thermo

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=    heat

            geothermal - having to do with the earth's heat
            thermodynamics - the study of the power of heat                       

Note:  --thermy    =    production of heat

ance &  ence / ancy & ency        

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     condition of being          

difference - condition of being different
reliance - condition of relying