Term
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Definition
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Term
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Definition
| 3-8yr period before menopause when the ovary begins to show signs of failure: |
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Term
| signs in menses of perimenopause: |
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Definition
| variation in menstrual cycle length and >FSH |
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Term
| process where oocytes are lost through degredation: |
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Definition
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Term
|
Definition
| # of oocytes capable of responding to FSH/LH decreases |
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Term
| pathophysiology (ovaries and uterus) of menopause: |
|
Definition
1. 2. 3. >FSH/LH
4. Endometrial development stops (5. menstrual cycles become irregular then cease |
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Term
| first physical manifestation of ovarian failure/< Estrogen production: |
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Definition
| vasomotor sx: hot flashes |
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Term
| hot flashes usually resolve wn: |
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Definition
| 2-3yrs or 3-6wks w hormone therapy |
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Term
| general effects of menopause:7 |
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Definition
1. vasomotor changes
2. sleep disturbances
3. urogenital changes
4. mood changes
5. sexual dysfxn
6. hair/skin/nail changes
7. osteoporosis |
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Term
| 4 urogenital changes of menopause: |
|
Definition
1. vaginal dryness
2. atrophy
3. increased vaginal pH
4. loss of urethrovesical junction support |
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Term
| list hiar/skin/nail changes: |
|
Definition
| 1. free androgens = facial hair
3. thin/brittle nails |
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Term
|
Definition
1. Estrogen replacement
2. Ca++ (1500mg/d)
3. Vit D (800mg/d)
4. weight bearing activity (30min/d) |
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Term
| list 3 bisphosphonates that inhibit osteoclast absorption: |
|
Definition
1. risendronat
2. ibandronate
3. alenfronate |
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Term
| 5 non-hormonal regimens for osteoporosis: |
|
Definition
1. risendronate
2. ibandronate
3. alendronate
4. calcium carbonate
5. raloxifene |
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Term
| serum lipid changes during menopause: |
|
Definition
1. Total cholesterol >
2. HDL <
3. LDL > |
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|
Term
| define premature ovarian failure: |
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Definition
|
|
Term
| dx of premature ovarian failure is confirmed by: |
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Definition
|
|
Term
| how does low body weight affect menopause: |
|
Definition
| adipose helps to produce and store estrogen, |
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|
Term
| dx criteria for menopause: |
|
Definition
| >45yo, amenorrhea for 12mo, absence of other causes + s/Sx |
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Term
|
Definition
1. hormone therapy
2. anti-depressants
3. soy/phytoestrogens
4. herbal |
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Term
| continuous unopposed estrogens from hormone therapy could result in: |
|
Definition
| 1. endometrial hyperplasia/CA |
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Term
| progestin must be given a minimum of __ ___ ea mo |
|
Definition
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Term
| 6 contraindications to hormone therapy: |
|
Definition
1. estrogen dependant malignancies
2. unexplained abn uterine bleeding
3. Hx of thromboembolism
4. liver dz
5. known/suspected pregnancy
6. hypersensativity |
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Term
|
Definition
| 1. when sx do not respond to non-medical tx |
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|
Term
| DEXA scan is recommended at age: |
|
Definition
| 65 or earlier if indicated |
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