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week 4
perception test
9
Biochemistry
Undergraduate 1
05/17/2013

Additional Biochemistry Flashcards

 


 

Cards

Term

what type of enzyme is chymotrypsin?

 

mettaloprotease

serine protease

aspartyl protease

cysteine protease

histidine protease

Definition
a serine protease
Term

Sarin is a nerve gas that attcks the enzyme acetylcholinesterase. it is structurally related to the molecule DIPF, which is used as an irreversible inhibitor of enzymes. with which amino acid do sarin and DIPF react with?

 

methionine, tryptophan, serine, histidine or cysteine?

Definition
serine
Term

what types of inhibitors are useful for mapping enzyme active sites?

 

non-competitive

competitve

affinity labels

group-specific reagents

suicide inhibitors

Definition
affinity labels, group-specific reagents and suicide inhibitors
Term
what does the catalytic triad found in many protease enzymes do?
Definition
it provides a reaction site that undergoes both acid-base and covalent catalysis during the cleavage of peptide bonds in the substrate
Term
if the plot of the reaction rate of an enzyme against substrate concentration produces a sigmoidal curve, then the enzyme is said to be what type of enzyme?
Definition
an allosteric enzyme
Term
what are isozymes?
Definition
enzymes that have the same function but different properties and are encoded by different genes
Term

zymogens are:

 

inactive enzymes

fibrous proteins involved in blood clotting

highly active proteases

coenzymes

protease inhibitors

Definition
they are inactive enzymes
Term

which of the following are mechainsm for the regulation of enzyme activity?

 

alkylation

phosphorylation

thermal activation

feedback inhibition

proteolytic cleavage

Definition

feedback inhibition 

proteolytic cleavage

  and phosphorylation

 

Term

true or false?

 

one of the effects of glycogen phosphorylation is to alter the net charge of the protein?

Definition
this is true
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