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Week 3, Neurulation
Medical School Devo
23
Other
Graduate
08/28/2011

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Cards

Term
What is the secondary neurulation?
Definition
a growth that comes from the primitive streak called the caudal eminence. This will eventually form a lumen and fuse with the neural canal around S2(conus medullaris)
Term
When do neural crest cells develope?
Definition
As the neural plate is folding up to make the neural tube
Term
What is Hirschsprung's Diesease?
Definition
Failure of enteric ganglia to develope (from neural crest cells) results in parts of the bowel being unable to initiate peristalsis
Term
Neural crest cells give rise to?
Definition
Prevertebral ganglia, enteric ganglia, dorsal root ganglia, melanocytes, craniofacial cartiledge and bone, pia and arachnoid mater, etc
Term
What is the central canal?
Definition
Cerebro-spinal fluid filled space running the entire spinal cord and contiguous with the ventricles of the brain. Remains of the developmental neural tube
Term
What is the mantel layer of the brain and spinal cord?
Definition
The mantel layer of the brain and spinal corWha is the presumptive grey matter
Term
What is the marginal layer of the brain and spinal cord?
Definition
The marginal layer is the presumptive white matter of the brain and spinal cord
Term
What forms the neural arch?
Definition
The lamina and pedicle of each vertebrae make one neural arch
Term
How does the neural arch form
Definition
Sclerotome on either end of the neural tube grows towards each other and forms the vertebrae
Term
The ribs form from what cell?
Definition
Somite cells
Term
The sternum forms from what cell?
Definition
Mesoderm (mesenchymal condensations)
Term
What is Spina Bifida?
Definition
Malformation of the neural arch leaving the spinal cord exposed
Term
Neural tube defects can be broadly categorized into what two categories?
Definition
Defects arising from failure of the neural tube to close (less severe)

Defects arising from failure of the neural tube to differentiate (more severe)
Term
What does mening mean?
Definition
Dealing with meninges
Term
What does Myelo mean?
Definition
Having to do with the spinal cord
Term
What does Encephalo mean?
Definition
having to do with brain tissue
Term
What does Cele mean?
Definition
having the dura-arachnoid sleeve continuous with the skin
Term
What does Cranio mean?
Definition
Term
What does Cranio mean?
Definition
Having to do with the brain
Term
What does Rachis mean?
Definition
Having to do with the backbone
Term
What does Shisis mean?
Definition
a fissure
Term
What does Inion mean?
Definition
External occipital protuberance of the skull
Term
What are the causes of Neural Tube defects?
Definition
Insulin, High Plasma Glucose, Maternal Diabetes, Retinoic Acid, Valprioic Acid, Hyperthermia, Vitamin A
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