Term
| Name the 3 functions of the complement system. |
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Definition
| Pathogen destruction, opsonisation and inflammatory mediators |
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Term
| What is bound to initiate the Classical pathway? |
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Definition
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Term
| What binds to Pathogen surface mannose initiating the lectin pathway? |
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Definition
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Term
| What initiates the Alternative pathway? |
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Definition
| Spontaneous splitting of C3. |
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Term
| In the classical pathway C3 convertase is formed by what? |
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Definition
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Term
| In the complement system, C5 initiates what? |
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Definition
| The formation of the membrane attacking complex. |
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Term
| The membrane attacking complex of complement is formed by what? |
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Definition
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Term
| Name 3 ways the body 'safeguards' against the complement system. |
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Definition
| Unbound C3 is inactivated by blood proteins, C3 convertase inactivation is increased by cell surface proteins and MAC 'kicked off' by cell surface proteins. |
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Term
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Definition
| Cell specific small soluble proteins. |
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Term
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Definition
| Sub-group of cytokines responsible for the recruitment of phagocytes. |
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