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Water-Soluable Vitamin
Water-Soluable Vitamin
94
Medical
Undergraduate 4
04/23/2008

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Cards

Term

What can transfer amino groups (NH3) to a keto acid to form the nonessential amino acids?

Definition
Vitamin B6
Term
Scaly dermatitis, anemia(small cell type), depression, confusion, abnormal brain wave pattern and convulsions.
Definition
Vitamin B6 deficiency
Term
Required for the synthesis of serotonin for tryptophan.
Definition
Vitamin B6
Term
Required for the synthesis of nucleic acids and heme(nonprotein portion of hemoglobin)
Definition
Vitamin B6
Term
Early symptoms include depression and confusion
Definition
Vitamin B6 Deficiency
Term
Advanced symptoms include abnormal brain wave patterns and convulsions.
Definition
Vitamin B6 deficiency
Term
required for the conversion of tryptophan to niacin.
Definition
Vitamin B6
Term
Influences cognitive performance, immune function and steroid hormone activity.
Definition
Vitamin B6
Term
RDA - Adults (19-50) 1.3mg/day with an Upper Limit of 100 mg/day
Definition
Vitamin B6
Term
Toxic effects include irreversible nerve degeneration.
Definition
Vitamin B6
Term
Significant sources of Vitamin B6 inlcude:
Definition
Meat, poultry, fish, legumes,liver, noncitrus fruits and fortified cereals.
Term
Three forms of Vitamin B6 are:
Definition
Pyridoxal, pyridoxine and pyridoxamine. All can form coenzyme PLP (pyridoxal phosphate).
Term
What can interfer with the absorption of vitamin    B6?
Definition
Alchohol disloges PLP and INH is an antagonist. INH is a medication used to treat tuberculosis bacteria.
Term
Foods lose ___ when heated.
Definition

Vitamin B6

Term
The bioavailability of this vitamin is lower in plant-derived foods than in nimal-derived foods.
Definition
Vitamin B6
Term
___ and ___ help cells to multiple including red blood cells and cells lining the GI tract.
Definition
Vitamin b12 and folate.
Term
Thiamine is the vitamin portion of the coenzyme ___?
Definition
TPP (Thiamine pyrophosphate)
Term
TPP assists in ____?
Definition
metabolism
Term
The main roles thiamine plays include:
Definition

(1) Removing a carbon from pyruvate to form acetyl coenzyme A and carbon dioxide.

 

(2) In the TCA cycle, TPP removes a carbon from a 5 carbon-compound to form a 4 carbon compound.

 

(3) occupies a special site in on the membranes of nerve cells. Processes in nerves and their respodning tissues, the muscles, rely heavily on thiamine.

Term
Nerve processes and their responding tissues, the muscles, rely heavily on ____?
Definition
Thiamine.
Term
Another name for Vitamin B1 is?
Definition
Thiamine
Term
Another name for Thiamine is?
Definition
Vitamin B1
Term
People who derive most their enery from empty-kcalorie items, like alcohol, risk ____?
Definition
Thiamine deficiency
Term

Wernicke-Korsakoff syndrome is a result of ____ deficiency?

Definition
Thiamine
Term
Thiamine deficiency can result in the disease ___?
Definition
Beriberi
Term
The symptoms of Beriberi include:
Definition
Damage to nervous systems as well as to the heart and other muscles.
Term
Deficiency symptoms include: Enlarged heart, cardiac failure, muscular weakness, apathy, poor short-term memory, confusion, irritability, anorexia and weight loss.
Definition
Thiamine Deficiency
Term
Thiamine Deficiency includes:
Definition
Enlarged heart, cardiac failure, muscular weakness, apathy, poor short-term memory, confusion, irritability, anorexia and weight loss.
Term
Significant sources of thiamine include:
Definition
Whole-grain, fortified or enriched grain products such as cornflakes and pork. Moderate amounts are in all nutritious food.
Term
IS there an Upper Limit for Thiamine, and if so, what is it?
Definition
No. There is no Upper Limit set.
Term
Toxicity Symptoms of thiamine include:
Definition
none reported.
Term
What effect does alcohol play on thiamine?
Definition
Alcohol impairs thiamine absorption and enhances the thiamine excretion in the urine.
Term
Diseases that can result from Thiamine deficiency include:
Definition
Beriberi and Wernicke-Korsakoff syndrome.
Term

An excellent source of thiamine is:

Definition

3 oz broiled, lean pork chop.

Term
The coenzyme forms of Riboflavin include:
Definition
FMN and FAD
Term
FMN and FAD both:
Definition
Accept 2 hydrogens during from the TCA cycle and delivery them to the electron transport chain.
Term
Symptoms of Riboflavin Deficiency include:
Definition

Inflammation of the mouth, skin, eyes and Gi track.

 

Inflammed eyelid, reddening of the cornea, photophobia, cheilosis (cracks in the corners of the mouth) and glossitis (loss of surface of the mouth) and inflammation characterized by skin lessons covered with greasy scales.

Term
Greatest contribution of Riboflavin come from?
Definition
Milk and milk products.
Term
A vegan who does not consume milk or milk products needs to acquire riboflavin from?
Definition

Dark greens and enriched grains.

Term
Another name for Riboflavin is?
Definition
Vitamin B2
Term
Another name for Riboflavin is?
Definition
Vitamin B2
Term
Chief function of riboflavin include:
Definition
Energy metabolism
Term
Can be easily destroyed by Ultraviolet or flouressent light.
Definition
Riboflavin
Term
The name niacin describes two stuctures ___ and ___.
Definition
Nicotinic acid and nicotinamide.
Term
The body can easily convert ____ to nicotinamide which is the major form of niacin in the blood.
Definition
Nicotinic acid
Term
NAD is simular to FAD in the regards that they both:
Definition
carry hydrogen from the TCA cycle to the electron transport chain.
Term
1 mg of niacin is equal to:
Definition
60 mg of tryptophan
Term
The body can convert ____ to niacin.
Definition
Tryptophan
Term
The Upper Limit of Niacin is
Definition
35 mg/day
Term
Niacin Deficiency disease, Pellagra produces symptoms of:
Definition

The four D's.

 

Diarrhea, Dermititis, dementia and eventually death.

Term
Diarrhea, abdominal pain, vomiting, glossitis, depression, apathy, fatigue, loss of memory, headache and bilateral symmetrical rash on areas exposed to sunlight.
Definition
Niacin Deficiency
Term
Niacin Deficiency include:
Definition
Diarrhea, abdominal pain, vomitting, glossitis, depression, apathy, fatigue, loss of memory, headache and bilateral symmetrical rash in areas exposed to sunlight.
Term

niacin flush results from exceeding the Upper Limit of 35mg/day and is the result of ___ and has the symptoms of____:

Definition
High doses of nicotinic acid. Nicotinic acid dilates the capillaries and causes a tingly sensation that can be painful.
Term
Toxic Symptoms of Niacin include:
Definition
painful flush, hives and rash (niacin flush), excessive sweating, blured vission, liver damage and impaired glucose tolerance.
Term
Corn has niacin, but the problem is?
Definition
most of the niacin is bound in complex carbohydrates and small peptides making it unavailable for absorption. Futhermore, corn is high in Leucine, which interfers with the tryptophan-to-niacin conversion.
Term
What amino acid can interfer with the tryptophan-to-niacin coversion?
Definition
Leucine
Term
Diets high in protein are never lacking ____.
Definition
niacin
Term
Major sources of niacin can be found in____ but alternatives include____.
Definition
Meat, Poultry and fish. Alternatives include: Enriched and whole grains, mushrooms, green leafy vegetables.
Term
A vegetarian can meet the niacin requirements with?
Definition
Enriched and whole grain, mushrooms, asparagus, and leafy green vegetables.
Term
Niacin is ___ vulnerable to losses during food preparation and storage than other water-soluble vitamins.
Definition
Less vulnerable
Term

How well does niacin hold up to heat from cooking?

Definition
Niacin can withstand reasonable cooking times.
Term
How does thiamine hold up to cooking.
Definition
Thiamine is destroyed prolonged cooking.
Term
What hinders thiamine in food?
Definition
Prolonged cooking destroys thiamine. Also, thiamine leaches into water when boiled or blanched.
Term
how does thiamine and niacin react to water?
Definition
They leach into it.
Term
What is another name for niacin?
Definition
Vitamin B3
Term
What is another name for Vitamin B3?
Definition
Niacin
Term
Biotin plays an important role in metabolism as a coenzyme that
Definition
carries activated carbon dioxide.
Term
What critical role does Biotin play in the TCA cycle?
Definition
It delivers a carbon to 3-carbon pyruvate to replenish oxaloacetate, the 4-carbon compound needed to combine with acetyl CoA to keep the TCA cycle turning.
Term
Outside of its role in the TCA cycle, The biotin coenzyme serves crucial roles in
Definition
gluconeogenesis, fatty acid synthesis and the breakdown of certain fatty acids and amino acids.
Term
Gluconeogenesis
Definition
The synthesis of glucose from noncarbohydrate sources such as amino acids and glycerol.
Term
Biotin is needed in very large or very small amounts?
Definition
very small amounts.
Term
How often do deficiencies in biotin occur?
Definition
rarely.
Term
What are significant sources of biotin?
Definition
Biotin is widespread in foods, so eating a variety of foods protects against biotin deficiency.
Term
Some ____ is synthesized by the GI tract, but the amount does not contribute much.
Definition
biotin.
Term
Some biotin can be synthesized by the?
Definition
GI Tract.
Term
What are the toxicity symptoms from biotin?
Definition
None are reported.
Term
What are the Biotin deficiency symptoms?
Definition
Depression, lethargy, hallucinations, numb or tingling sinsation in the arms and legs; red, scaly rash arount the eyes, nose and mouth; hair loss.
Term
Depression, lethargy, hallucinations, numb or tingling sinsation in the arms and legs; red, scaly rash arount the eyes, nose and mouth; hair loss.
Definition
Biotin Deficiency.
Term
Biotin deficiency includes ___,lethargy, hallucinations, numb or tingling sensation in the arms and legs, red scaly rash around eyes, nose and mouth; hair loss.
Definition
Depression
Term
Biotin deficiency includes depression, __________, hallucinations, numb or tingling sensation in the arms and legs, red scaly rash around eyes, nose and mouth; hair loss.
Definition
lethargy
Term
Biotin deficiency includes depression, lethargy, ________________, numb or tingling sensation in the arms and legs; red scaly rash around eyes, nose and mouth; hair loss.
Definition
hallucinations
Term
Biotin deficiency includes depression, lethargy, hallucinations, ________________; red scaly rash around eyes, nose and mouth; hair loss.
Definition
numb or tingling sensation in the arms and legs
Term
Biotin deficiency includes depression, lethargy, hallucinations, numb or tingling sensation in the arms and legs; ________________; hair loss.
Definition
red scaly rash around eyes, nose and mouth
Term
Biotin deficiency includes depression, lethargy, hallucinations, numb or tingling sensation in the arms and legs; red scaly rash around the eyes, nose and mouth; ________________.
Definition
hair loss
Term
What is special about Pantothenic Acid?
Definition
It is involved in over 100 different steps in the synthesis of lipids, neurotransmitters, steriod hormones and hemoglobin as part of the chemical structure of coenzyme A - the CoA that forms acetyl CoA.
Term
What are the symptoms
Definition
Deficiencies are rare, but symptoms include general failure of body's systems, GI distress, fatigue and neurological disturbances.
Term
Vitamin B6 deficiency symptoms
Definition
depression and confusion followed by by abnormal brain wave patterns and convulsions.
Term
What is important about vitamin B6?
Definition
It can transfer amoino groups (nh2) to keto acids to make the nonessencial amino acids. It is required for transferring tryptophan to niacin and for the synthesis of nucleic acids and heme (the nonprotein portion of hemoglobin)
Term
What are the toxic symptoms of Vitamin B6
Definition
Depression, fatigue, headaches, irritability, nerve damage causing numbness and muscle weakness leading to an inability to walk, convulsions and skin lesions.
Term
where is vitamin b6 stored?
Definition
unlike other water-soluable vitamins, vitamin b6 is stored in the muscle tissue.
Term
What does homocysteine do and what fixes it.
Definition
Homocysteine is an naturally occuring amino acid that is associated with blood clots and arterial wall deterioration. Folate acid breaks down homocysteine. Fortified grain products have Folate acid in it.
Term
What are the main functions of Folate?
Definition

Part of the coenzymes THf (Terahydrofolate) and DHF (Dihydrofolate) which are required for DNA synthesis and therefore important in new cell formation.

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