Term
| What are the three cell layers of a papillary hidradenoma? |
|
Definition
| Two cell layers with luminal glandular cells and underlying myoepithelial cells |
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Term
| You find a case of pelvic inflammatory disease and, upon culture, you come across intracellular gram (-) diplococcus species. What could it be? |
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Definition
|
|
Term
| Chancroid, in addition to single or multiple painful chancres, is accompanied by what else? |
|
Definition
| suppurative inguinal lymphadenopathy |
|
|
Term
| What structures are diagnostic of Granuloma inguinale? |
|
Definition
| Donovan bodies (located within macrophages and detected by silver stain) |
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Term
| With Granuloma inguinale, what happens to the lymphatics? |
|
Definition
| They undergo fibrosis and lead to massive edema of the external genitalia. |
|
|
Term
| What is the species that causes lymphogranuloma venereum? |
|
Definition
|
|
Term
| What is the species that causes granuloma inguinale? |
|
Definition
|
|
Term
| Describe the pathogenesis of lymphogranuloma venereum? |
|
Definition
| Initially short-lived vulvar ulcer followed by subsequent painful inguinal and perirectal lymphadenopathy which may become suppurative (buboes) |
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|
Term
| What is the most common vulvar cancer and how may it appear as? |
|
Definition
| Squamous cell carcinoma (may appear as "leukoplakia") |
|
|
Term
| How does extramammary Paget disease clinically present? |
|
Definition
| as a erythematous patch usually on the labia majora |
|
|
Term
| How is extramammary Paget disease different from the Paget disease of the breast? |
|
Definition
| There is uno underlying invasive carcinoma (confined to the epithelium) |
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|
Term
| What stain do we use to help distinguish extramammary Paget disease from a malignant melanoma? |
|
Definition
| Mucin stain (also want a negative HMB 45 marker) |
|
|
Term
| When is the peak incidence for malignant melanoma? |
|
Definition
|
|
Term
| What stains help confirm amelanotic lesions as being malignant melanomas? |
|
Definition
| S-100, HMB 45, and MART-1 |
|
|
Term
| Hematocolpos of the vagina results from what? |
|
Definition
|
|
Term
| What are the two common cysts of the Vagina? |
|
Definition
| Gartner duct cyst, mucous cyst (minor ducts) |
|
|
Term
| Gartner's duct cysts are derived from what? |
|
Definition
| remnants of the Wolffian ducts (mesonephric ducts) |
|
|
Term
| What causes atrophic vaginitis? |
|
Definition
| postmenopausal estrogen deficiency |
|
|
Term
| For Gardnerella vaginitis, what are seen on a wet prep or PAP smear? |
|
Definition
|
|
Term
| Vaginal adenosis arose primarily through what action? |
|
Definition
| expectant mothers taking DES to prevent spontaenous abortion |
|
|
Term
| Vaginal adenosis is derived from what,and what is it a precursor to? |
|
Definition
| derived from remnants of mullerian glands/ precursor lesion to clear cell adenocarcinoma |
|
|
Term
| What is the most common vaginal malignancy of girls less than 5 years old? |
|
Definition
| embryonal rhabdomyosarcoma |
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