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Viruses
N/A
38
Pathology
Graduate
02/16/2012

Additional Pathology Flashcards

 


 

Cards

Term
Parvoviridae-B-19
Definition
Single Stranded DNA
aplastic anemia
Term
Poxviridae
Definition
small pox
double stranded DNA
only one that does not replicate in the nucleus
Term
Herpesviridae
Definition
double stranded DNA
cytomegalovirus
epstein-barr virus
vricella zoster virus
herpes simplex virus (1 and 2)
Human herpes virus 6,7,8
cold sores, encephalitis, chicken pox/zoster, mononucleosis, pneumonitis, congenital defects, mental retardation, cerebral palsy, retinitis, Kaposi's sarcoma and other tumors
Term
adenoviridae
Definition
adenovirus
double stranded DNA
uncommon cold
conjunctivitis, gastroenteritis
Term
PAPILLOMAVIRIDAE
(progressive multifocal)
Definition
papilloma virus- associated with 99% of all cervical cancers
Double stranded DNA
warts, cervical hyperplasia
Term
Human Cytomegaloviruses (HCMV)
Definition
outer lipid envelope surrounding a capsid
contains both DNA and RNA
must bind to a sell surface heparan sulfate proteoglycan
manifests disease in most organ systems
Treat with ganciclovir and valganciclovir for immunocompromised patients
Term
Cytomegalic Inclusion Disease (CID)
Definition
condition caused by infection with CMV
rash, thrombocytopenic purpura
cerebral calcification (owl like inclusions)
birth defects, cerebral palsy
mononucleosis
systemic infections in organ/tissue transplants
Term
HIV initial acute infection
Definition
CD4 + levels drop
results in mono like syndrome with a burst of virus
Term
HIV clinical latent period
Definition
blood levels of HIV drop
replication continues in lymph nodes
Term
HIV late phase
Definition
CD4+ cells significantly drop
lymph nodes destroyed
virus levels high-correlates with AIDS development
opportunistic infections
Term
AIDS
Definition
HIV 1
Term
Cervical Carcinoma
Definition
HPV 16, 18, 31
papillomavirus
Term
chickenpox
Definition
varicella virus
Term
cold sores
Definition
herpes simplex virus 1
herpesvirus
Term
common cold
Definition
adenoviruses, coronaviruses, rhinoviruses (picornavirus)
Term
diarrhea
Definition
norwalk virus (calicivirus)
rotavirus (reovirus)
Term
genital herpes
Definition
herpes simplex virus 2
herpesvirus
Term
hemorrhagic fevers
Definition
dengue virus (flavivirus)
ebola and margus viruses (filovirus)
lassa fever virus (arenavirus)
Term
hepatitis
Definition
hep a virus (picornavirus)
hep b virus (hepadnavirus)
hep c virus (flavivirus)
Term
influenza
Definition
influenza A and B
helical, enveloped, -ss RNA 8 seg
Term
measles
Definition
measles virus
helical, enveloped, - ss RNA cont
Term
mononucleosis
Definition
epstein-barr virus (herpes virus)
cytomegalovirus (herpes virus)
Term
mumps
Definition
mumps virus
Term
poliomyelitis
Definition
poliovirus 1,2, and 3
Term
rabies encephalitis
Definition
rabies virus
helical, enveloped, -ss cont.
Term
SARS
Definition
SARS coronavirus
helical, Enveloped, +ss RNA cont.
Term
smallpox
Definition
variola virus
complex, enveloped, ds linear DNA
Term
warts
Definition
HPV 1,2, and 4
Term
yellow fever
Definition
yellow fever virus
Term
polio
Definition
icosahedral
naked
+ ss RNA
Term
West Nile
Definition
icosahedral
enveloped
+ss RNA
Term
HIV
Definition
icosahedral
enveloped
+ ss RNA 2 copies
Term
Ebola
Definition
helical
enveloped
- ss RNA cont
Term
Rift V.
Definition
helical
enveloped
-ss RNA 3 seg.
Term
Lassa
Definition
helical
enveloped
-ss RNA 2 seg
Term
Papilloma
Definition
icosahedral, naked, ds circular DNA
Term
Hep B
Definition
Icosahedral, enveloped, ds circle grapped DNA
Term
CMV, EBV, VZ structure
Definition
icosahedral, enveloped, ds linear DNA
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