Term
| T/F Viruses can make their own proteins |
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Definition
|
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Term
| T/F Viruses replicate by "division" |
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Definition
| False, they are assembled |
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Term
| T/F the DNA of a virus can be linear or circular |
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Definition
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Term
| T/F Viral DNA is only double stranded |
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Definition
| False, it can be single stranded |
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Term
| T/F Viral RNA is only positive sense |
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Definition
| False, it can be positive, negative, double-stranded, or ambisense |
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Term
| What is the function of the virus capsid or envelope? |
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Definition
| Package space, protection, delivery vehicle |
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Term
| T/F removal of the outer surface of a virus will render it inactive |
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Definition
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Term
| What part of the virus is made for the ability to withstand harsh environmental conditions |
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Definition
|
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Term
| T/F the envelope is able to withstand harsh environmental conditions |
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Definition
| False, it can readily be disrupted |
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Term
| T/F an enveloped virus may withstand the intestinal tract |
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Definition
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Term
| The simplest viral structures are? |
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Definition
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Term
| T/F all of the negative strand RNA viruses are enveloped |
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Definition
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Term
| The interstitial space between the nucleocapsid and the envelope is called the _____? |
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Definition
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Term
| What are the eight steps to viral replication? |
|
Definition
| 1. Recognition of target cell 2. Attachment 3. Penetration 4. Uncoating 5. Synthesis 6. Assembly 7. Budding 8. Release |
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|
Term
| What are the four steps in early phase replication? |
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Definition
| Recognition, attachment, penetration, and uncoating |
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|
Term
| What are the steps involved with the late phase? |
|
Definition
| Synthesis, Assembly, Budding, and release |
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Term
| The uncoating stage renders a virus non-infective and unidentifiable, is called what phase? |
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Definition
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Term
| The period in which extracellular infectious virus is not detected and includes the eclipse period is termed? |
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Definition
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Term
| The yield of infectious viruses per cell is also called? |
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Definition
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Term
| The receptors on a cell for a virus may be composed of _____ and_____? |
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Definition
| Proteins and carbohydrates on glycoproteins |
|
|
Term
| What is the receptor and target cell of the Epstein Barr virus? |
|
Definition
| C3d receptor on the B cell |
|
|
Term
| What is the receptor and target cell of HIV? |
|
Definition
| CD4 receptor on a Helper T cell |
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|
Term
| How do most non-enveloped viruses enter the cell? |
|
Definition
|
|
Term
|
Definition
| When the capsid proteins are exposed (during attachment) they help the viral genome slip through the membrane |
|
|
Term
| How do most enveloped viruses enter the cell? |
|
Definition
| They fuse membranes and deliver the genome directly |
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|
Term
| What are the most important steps in viral replication? |
|
Definition
| Transcription, Translation, and Replication |
|
|
Term
| What enzyme do DNA viruses use to make mRNA? |
|
Definition
| DNA dependent RNA polymerase II |
|
|
Term
| Where do most RNA viruses produce mRNA? |
|
Definition
|
|
Term
| T/F the host cell provides the enzymes for RNA viruses to replicate |
|
Definition
| False, the host cell has no means for replicating RNA |
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|
Term
| What two types of viruses are classified as infectious nucleic acids? |
|
Definition
| Naked genome DNA viruses and Positive sense RNA viruses. Due to the ability to initiate replication upon injection into the cell |
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Term
| The site of replication initiation of a DNA virus is called? |
|
Definition
|
|
Term
| T/F the smaller the DNA virus the more dependent it is on the host cell |
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Definition
|
|
Term
| The RNA virus genome must encode for what enzymes? |
|
Definition
| RNA-dependent RNA Polymerases |
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|
Term
| Transcription and replication of the negative strand RNA viruses occurs where? |
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Definition
|
|
Term
| T/F RNA viruses are prone to mutation |
|
Definition
|
|
Term
| What RNA-dependent DNA polymerase can be found in retroviruses? |
|
Definition
|
|
Term
| For a virus to acquire an envelope it must use a process known as_____? |
|
Definition
|
|
Term
| What determines the site of budding? |
|
Definition
| the type of genome and the protein sequence |
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|
Term
| Naked viruses are generally released from the host cell by what process? |
|
Definition
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|
Term
| Enveloped viruses are generally released from the host cell by what process? |
|
Definition
|
|
Term
| T/F viruses may also spread their infection to daughter cells rather than other host cells |
|
Definition
|
|
Term
| What is the most common route for viral infection? |
|
Definition
|
|
Term
|
Definition
| the transport of the virus in the blood |
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|
Term
| Definition: Abortive infection |
|
Definition
|
|
Term
| Definition: Lytic infection |
|
Definition
|
|
Term
| Definition: Persistant infection |
|
Definition
| Infection without cell death |
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|
Term
| Definition: Nonpermissive cell |
|
Definition
| Does not allow the replication of certain types of viruses |
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|
Term
| Definition: Permissive cell |
|
Definition
| Cell provides all the machinery to support complete replication of virus |
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|
Term
| Definition: Semipermissive cell |
|
Definition
| Cell may support some but not all steps to replication |
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|
Term
| A DNA virus that stimulates uncontrollable cell growth is called a ______ virus? |
|
Definition
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