Term
|
Definition
Picornavirus
more common in sanitary nations - fecal oral route. 2-3 week incubation.
Test via neutralization of spinal or stool.
Clinical - sub, fever, aseptic meningitis, Paralytic (spinal, bulbar)
Vaccine - live, attenuated (IgA, IgG) or killed (IgG only, no herd immunity) |
|
|
Term
|
Definition
Virus: Picornavirus, enterovirus
Diseases: Meningitis, hand foot mouth
Epi:worldwide, summer and fall
Transmission: Humans, fecal Oral, aerosol
Pathogenesis: Viremia, GI tract
Lab Diagnosis: CPE, titer (IgG), Neutralization
NoVax |
|
|
Term
|
Definition
Virus: Picorna, entero
Diseases: aseptic meningitis, URI, dirrhea, hem. conjuct.
Epi: worldwide
Transmission: Fecal Oral
Pathogenesis: Entero, Viremia.
Lab: Isolation of virus in tissue, too many types for serology.
NoVax |
|
|
Term
|
Definition
Virus: Picornavirus, rhino
Diseases: common cold
Epi: most common, fall winter
Transmission: aerosol, surface to mucosal
Patho: limited to URI, no viremia.
Diagnostic: cell culture, rarely used
NoVax, too many serotypes. |
|
|
Term
| Norwalk Virus (norovirus) |
|
Definition
Virus: Picornavirus (calcivirus)
Disease:dirrhea
Epi: group settings, carribean
Transmission: Fecal Oral
Pathogenesis:GI tract
Lab: PCR, rarely
NoVax |
|
|
Term
|
Definition
Virus:Reovirus
Diseases: viral gastroenteritis
Epi: worldwide
Transmission: Fecal Oral
Patho: GI, water dirrhea
Lab: stool, ELISA
Vaccine: live attenuated (most common), and live reassortant (5 strain) |
|
|
Term
|
Definition
Virus:Adenovirus
Diseases: Upper/Lower URI, conjunctivitis, common cold
Epi: Military recruits, worldwide
Trans: Respiratory, eyes, fecal oral
Pathogenesis:URI, eyes
Diagnostic: CPE, ABtiter, flantibody
Vaccine: military, 3,4,7 |
|
|
Term
|
Definition
Virus:orthomyxovirus
Diseases: Influenza A,B
Epi: Epidemics caused by drift, Pandemics caused by shift. Animal and human hosts. Animal hosts cause shift. Viremia not common.
Trans:aerosol
Patho:URI, short incubation.
Diagnostics: Serum, florescent antibody
Vaccine:killed, live attenuated
Chemo:neuroamdidase inhibitors (tamiflu, relenza) |
|
|
Term
| Paramyxoviruses (Croup, SRV |
|
Definition
Virus:Paramyxoviruses
Diseases: RSV, Parainfluenza (Mumps, Measels) CROUP
EPI:no shift, subclinical. Virimea only in MM.
Trans:Aerosol
Patho: URI, LRI
Diagnostic:Hemmaglutination.
Vaccine:Passive, Highdose antibody
Chemo:some, aerosol. |
|
|
Term
|
Definition
picornavirus
Epi:Fecal, brief viremia. short incubation
Disease: aches, vomiting, jaundice. Immune activated liver attack.
Lab: IgM titer
Treatment: none
Killed vaccine, plus hi-dose Ig |
|
|
Term
|
Definition
Hepadnavirus
Trans:blood, birth, STD. Long incubation
Patho: causes immune attack. chronic carrier state (5%) Risk of carcinoma.
Lab:HBsAb (surface) - potential to miss for window-phase.
Treatment:a interferon, reverse trans inhibitor
Vaccine: Killed, high Ig serum, education |
|
|
Term
|
Definition
picornavirus
Epi:Blood (most common). Possible STD/maternal
Patho:immune response. Chronic carrier possible. carcinoma possible
Lab: HCV serum, PCR (viral load)
Treatment:alpha interferon, ribavirin
No Vax, No Ig |
|
|
Term
|
Definition
defective virus - HBV surface antigen
Epi:blood,STD,maternal
Path:carrier state, chronic
Lab: Dantigen or Dantibody
Treatment: alpha interferon
Vaccine:HBV |
|
|
